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The map label for this gene is pdxA [H]

Identifier: 92113047

GI number: 92113047

Start: 1033856

End: 1034875

Strand: Direct

Name: pdxA [H]

Synonym: Csal_0919

Alternate gene names: 92113047

Gene position: 1033856-1034875 (Clockwise)

Preceding gene: 92113046

Following gene: 92113048

Centisome position: 27.97

GC content: 71.27

Gene sequence:

>1020_bases
ATGGCCTCCTCCCCGCTACTGGCCCTGACCACGGGGGAGCCCGCGGGGATCGGGCCGGATCTGACGCTGGCCCTGGCCGC
GTCGTGGGGGACGCTCGAAGCACGTGTCGTGGCGGTCGGCGATCCGGCATTGCTGGCCGCGCGTGCCGCGCGCCTGGCGC
TTGACGTACGCATCGTGCCGCTCGCCGACGGCGACCCGGTGCCGTCCCCCCGCGACGGGGTGCTGCCGGTGTGGCCCGTG
GCCCTGCGCGCACCGGTGGAGGCCGGGCGCCTCGATCCTGCCAATGCCGGCTATGTGCTCGAGACGCTCGATGTCGCCAT
CGCCGCGTGTCGCCAGGGGCGCGCCGATGCCATGGTGACCGCTCCCTTGCACAAGGGGGCCATCATCGAAGGCGGCTATC
CCGACTTCACCGGCCATACCGAGTATCTGCGCGATGCCTGCGATGTCGACGAGGTAGTCATGCTGCTGGCCACCGAGCGC
ACCGAACCGGCATTGCGCGTGGCGCTGGCCACGACGCACCTGCCCTTGCGTGCGGTGGCCGATGCCATCGACGCCGGCGG
GCTGCGGCGCGTGCTGACGATCCTCGAGGCGGACCTGCGGCGCCGCTTCGGCATCGCGCGGCCACGCATCCTGGTCTGCG
GTCTTAACCCGCATGCCGGTGAAGATGGCCATCTGGGCGTGGAGGAGCGTGATATCATCGCGCCGACACTCGCGGCGATG
CGCGGCGAGGGCCTGGACCTCGTCGGCCCCCTGCCCGCCGATACCCTGTTCACGCCGCGCCATCTGGCCGATGCCGATGC
GGTGTTGGCCATGTACCACGACCAGGGCCTGCCGGTACTGAAGTACGCCGGTTTTGGCGAGGCCGCCAACGTGACCCTGG
GCTTGCCGTTGATTCGCACTTCCGTGGATCACGGCACGGCGCTCGATCTGGCCGGAAGCGGCCGGGCCGAGGCCGGCAGC
CTGCGCGTGGCGCTCGATGTCGCCGTCCGCATGGTCCGTGGTGGCACGTCTCGCCCCTGA

Upstream 100 bases:

>100_bases
CGCTGTTCCAGCGCAAGGTGAGCGACGAGATGGAAGCCTGGACGCAGGAAATCCGCTCCGGGGCCTATATCGACAACCGC
CTGGAAGACGGCCGCCAGTG

Downstream 100 bases:

>100_bases
ATGCCCGATTTCCCCAAGGAACACGCAACGCCCATGTCCAATCGCCCTCCGGCCCATCAGGCCCGTAAACGCTTCGGCCA
GAATTTCTTGCGCGACACCG

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MASSPLLALTTGEPAGIGPDLTLALAASWGTLEARVVAVGDPALLAARAARLALDVRIVPLADGDPVPSPRDGVLPVWPV
ALRAPVEAGRLDPANAGYVLETLDVAIAACRQGRADAMVTAPLHKGAIIEGGYPDFTGHTEYLRDACDVDEVVMLLATER
TEPALRVALATTHLPLRAVADAIDAGGLRRVLTILEADLRRRFGIARPRILVCGLNPHAGEDGHLGVEERDIIAPTLAAM
RGEGLDLVGPLPADTLFTPRHLADADAVLAMYHDQGLPVLKYAGFGEAANVTLGLPLIRTSVDHGTALDLAGSGRAEAGS
LRVALDVAVRMVRGGTSRP

Sequences:

>Translated_339_residues
MASSPLLALTTGEPAGIGPDLTLALAASWGTLEARVVAVGDPALLAARAARLALDVRIVPLADGDPVPSPRDGVLPVWPV
ALRAPVEAGRLDPANAGYVLETLDVAIAACRQGRADAMVTAPLHKGAIIEGGYPDFTGHTEYLRDACDVDEVVMLLATER
TEPALRVALATTHLPLRAVADAIDAGGLRRVLTILEADLRRRFGIARPRILVCGLNPHAGEDGHLGVEERDIIAPTLAAM
RGEGLDLVGPLPADTLFTPRHLADADAVLAMYHDQGLPVLKYAGFGEAANVTLGLPLIRTSVDHGTALDLAGSGRAEAGS
LRVALDVAVRMVRGGTSRP
>Mature_338_residues
ASSPLLALTTGEPAGIGPDLTLALAASWGTLEARVVAVGDPALLAARAARLALDVRIVPLADGDPVPSPRDGVLPVWPVA
LRAPVEAGRLDPANAGYVLETLDVAIAACRQGRADAMVTAPLHKGAIIEGGYPDFTGHTEYLRDACDVDEVVMLLATERT
EPALRVALATTHLPLRAVADAIDAGGLRRVLTILEADLRRRFGIARPRILVCGLNPHAGEDGHLGVEERDIIAPTLAAMR
GEGLDLVGPLPADTLFTPRHLADADAVLAMYHDQGLPVLKYAGFGEAANVTLGLPLIRTSVDHGTALDLAGSGRAEAGSL
RVALDVAVRMVRGGTSRP

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=332, Percent_Identity=55.421686746988, Blast_Score=345, Evalue=3e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 35262; Mature: 35131

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASSPLLALTTGEPAGIGPDLTLALAASWGTLEARVVAVGDPALLAARAARLALDVRIVP
CCCCCEEEEECCCCCCCCCCEEEEEEECCCCEEEEEEEECCHHHHHHHHHHEEEEEEEEE
LADGDPVPSPRDGVLPVWPVALRAPVEAGRLDPANAGYVLETLDVAIAACRQGRADAMVT
ECCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEE
APLHKGAIIEGGYPDFTGHTEYLRDACDVDEVVMLLATERTEPALRVALATTHLPLRAVA
CCCCCCEEEECCCCCCCCCHHHHHHHCCHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHH
DAIDAGGLRRVLTILEADLRRRFGIARPRILVCGLNPHAGEDGHLGVEERDIIAPTLAAM
HHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHH
RGEGLDLVGPLPADTLFTPRHLADADAVLAMYHDQGLPVLKYAGFGEAANVTLGLPLIRT
CCCCCEEECCCCCCCCCCCHHHCCCHHEEEEEECCCCCEEEECCCCCCCCEEECCHHEEE
SVDHGTALDLAGSGRAEAGSLRVALDVAVRMVRGGTSRP
CCCCCCEEEECCCCCCCCCCEEEHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ASSPLLALTTGEPAGIGPDLTLALAASWGTLEARVVAVGDPALLAARAARLALDVRIVP
CCCCEEEEECCCCCCCCCCEEEEEEECCCCEEEEEEEECCHHHHHHHHHHEEEEEEEEE
LADGDPVPSPRDGVLPVWPVALRAPVEAGRLDPANAGYVLETLDVAIAACRQGRADAMVT
ECCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEE
APLHKGAIIEGGYPDFTGHTEYLRDACDVDEVVMLLATERTEPALRVALATTHLPLRAVA
CCCCCCEEEECCCCCCCCCHHHHHHHCCHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHH
DAIDAGGLRRVLTILEADLRRRFGIARPRILVCGLNPHAGEDGHLGVEERDIIAPTLAAM
HHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHH
RGEGLDLVGPLPADTLFTPRHLADADAVLAMYHDQGLPVLKYAGFGEAANVTLGLPLIRT
CCCCCEEECCCCCCCCCCCHHHCCCHHEEEEEECCCCCEEEECCCCCCCCEEECCHHEEE
SVDHGTALDLAGSGRAEAGSLRVALDVAVRMVRGGTSRP
CCCCCCEEEECCCCCCCCCCEEEHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA