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The map label for this gene is surA

Identifier: 92113046

GI number: 92113046

Start: 1032549

End: 1033856

Strand: Direct

Name: surA

Synonym: Csal_0918

Alternate gene names: 92113046

Gene position: 1032549-1033856 (Clockwise)

Preceding gene: 92113045

Following gene: 92113047

Centisome position: 27.93

GC content: 65.37

Gene sequence:

>1308_bases
ATGCGCTTGAGATCGTTCGCCTTTCTGGGCTTCATGCTGCTGGTGGCGATGGCGCCATCGATGGCGTCGGCGCAGCCCCA
GCCGCTGGACCGCATCGTGGCGGTCGTCAACAAGGATGCGATCATGCAGAGCCGGCTCGAGGATCGCGTCACGCAGGTGC
GCCGCCAAATGGCGAGCCGCAACGTTCCCGCGCCGAACGAGGCGGATCTGCGACGCCAGGTGCTCGACCGCATGATTCTC
GAGCAGATTCAGCTGCAGATGGCCGAGCGCGCCAACTTGAGCATCGACGATACCCAGCTCAACGCGACCGTGCGGGGTAT
CGCCGAGGACAACGGCATGTCGATGGACGAGTTCGCCGATGCCCTCGAGGAAGATGGCATGTCCCTGGCCTCGATGCGCG
AGCAGGTGCGTCGCGAGATGCTGTTGCGTCAGGTACAGCAGAGCCAGGTCGCGAGCCGCGTCAACGTCACCGACCGCGAA
GTGGAACGTTACCTCGATCAGCAAGGCGAGACCGCCGATACCGCGTATCATCTCGCCCACATTCTCGTCTCGGTGCCCGA
GTCGCCCACGCCCGAGCAGGTCGAGCAGGCACAGGCCAAGGTGCGTGACTTGTATCGGCAGTTGCAGAATGGCGCCAACT
TCGCGCAGCTCGCGACGGCCGAGTCCGACGGCCAGCAGGCGCTGTCGGGCGGCGACCTCGGGTGGCGGCGTGGCGATCAG
CTGCCCAGCCTGTTCGCCGACGTGGTGCCCACGCTATCCAACGGCGAGGTCAGCGAGCCCATTCGCAGCCCCAGCGGCTT
CCATCTGGTCAAGCTGATCGATACGCGTGGCCAGCAGGGCGAGCAGAAGCGCGTGGTCACCGAGAACCGTGTGCGCCATA
TCCTGATCGGCACCAACCCGAACCGCAACGATCAGCAGGCCGAAGCGCTGGCCCGCGACATACGTCAGCGTATCGCCAAT
GGCGAGAGTTTCGCCGCGCTGGCACAGGAATACAGCGACGACGATGGCAGCGCCCTCGACGGCGGCGAGCTGGGCTGGAC
GCGTCCCGGCCAGATGGTGCCGGCGTTCGAAGATGCCGTGAAAGCGCTGGATGTCGGTGAACTGTCGCAGCCGGTACGTT
CACGCTTCGGGTACCACGTGATCGAGCTCGAGGATCGGCGTCGTCAGGACGTGACCCGCGACGCGCAGCGCGAGCAGATT
CGTCAGACGCTGTTCCAGCGCAAGGTGAGCGACGAGATGGAAGCCTGGACGCAGGAAATCCGCTCCGGGGCCTATATCGA
CAACCGCCTGGAAGACGGCCGCCAGTGA

Upstream 100 bases:

>100_bases
CGATTCCCGGCTACCGGGCGACGCGCTTCTGATCCACGCTGGCAGGTATTCACCGTCGGTGCTCGCGCCGACCACAAGAC
AGTAACGTAGAGAGGACTTC

Downstream 100 bases:

>100_bases
TGGCCTCCTCCCCGCTACTGGCCCTGACCACGGGGGAGCCCGCGGGGATCGGGCCGGATCTGACGCTGGCCCTGGCCGCG
TCGTGGGGGACGCTCGAAGC

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MRLRSFAFLGFMLLVAMAPSMASAQPQPLDRIVAVVNKDAIMQSRLEDRVTQVRRQMASRNVPAPNEADLRRQVLDRMIL
EQIQLQMAERANLSIDDTQLNATVRGIAEDNGMSMDEFADALEEDGMSLASMREQVRREMLLRQVQQSQVASRVNVTDRE
VERYLDQQGETADTAYHLAHILVSVPESPTPEQVEQAQAKVRDLYRQLQNGANFAQLATAESDGQQALSGGDLGWRRGDQ
LPSLFADVVPTLSNGEVSEPIRSPSGFHLVKLIDTRGQQGEQKRVVTENRVRHILIGTNPNRNDQQAEALARDIRQRIAN
GESFAALAQEYSDDDGSALDGGELGWTRPGQMVPAFEDAVKALDVGELSQPVRSRFGYHVIELEDRRRQDVTRDAQREQI
RQTLFQRKVSDEMEAWTQEIRSGAYIDNRLEDGRQ

Sequences:

>Translated_435_residues
MRLRSFAFLGFMLLVAMAPSMASAQPQPLDRIVAVVNKDAIMQSRLEDRVTQVRRQMASRNVPAPNEADLRRQVLDRMIL
EQIQLQMAERANLSIDDTQLNATVRGIAEDNGMSMDEFADALEEDGMSLASMREQVRREMLLRQVQQSQVASRVNVTDRE
VERYLDQQGETADTAYHLAHILVSVPESPTPEQVEQAQAKVRDLYRQLQNGANFAQLATAESDGQQALSGGDLGWRRGDQ
LPSLFADVVPTLSNGEVSEPIRSPSGFHLVKLIDTRGQQGEQKRVVTENRVRHILIGTNPNRNDQQAEALARDIRQRIAN
GESFAALAQEYSDDDGSALDGGELGWTRPGQMVPAFEDAVKALDVGELSQPVRSRFGYHVIELEDRRRQDVTRDAQREQI
RQTLFQRKVSDEMEAWTQEIRSGAYIDNRLEDGRQ
>Mature_435_residues
MRLRSFAFLGFMLLVAMAPSMASAQPQPLDRIVAVVNKDAIMQSRLEDRVTQVRRQMASRNVPAPNEADLRRQVLDRMIL
EQIQLQMAERANLSIDDTQLNATVRGIAEDNGMSMDEFADALEEDGMSLASMREQVRREMLLRQVQQSQVASRVNVTDRE
VERYLDQQGETADTAYHLAHILVSVPESPTPEQVEQAQAKVRDLYRQLQNGANFAQLATAESDGQQALSGGDLGWRRGDQ
LPSLFADVVPTLSNGEVSEPIRSPSGFHLVKLIDTRGQQGEQKRVVTENRVRHILIGTNPNRNDQQAEALARDIRQRIAN
GESFAALAQEYSDDDGSALDGGELGWTRPGQMVPAFEDAVKALDVGELSQPVRSRFGYHVIELEDRRRQDVTRDAQREQI
RQTLFQRKVSDEMEAWTQEIRSGAYIDNRLEDGRQ

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains

Homologues:

Organism=Escherichia coli, GI1786238, Length=420, Percent_Identity=39.5238095238095, Blast_Score=300, Evalue=1e-82,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): SURA_CHRSD (Q1QZ33)

Other databases:

- EMBL:   CP000285
- RefSeq:   YP_572974.1
- ProteinModelPortal:   Q1QZ33
- SMR:   Q1QZ33
- STRING:   Q1QZ33
- GeneID:   4027425
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_0918
- NMPDR:   fig|290398.4.peg.910
- eggNOG:   COG0760
- HOGENOM:   HBG391483
- OMA:   RHILIKT
- BioCyc:   CSAL290398:CSAL_0918-MONOMER
- HAMAP:   MF_01183
- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N; SSF109998 Trigger_fac_C_bac

EC number: =5.2.1.8

Molecular weight: Translated: 48963; Mature: 48963

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS01096 PPIC_PPIASE_1; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLRSFAFLGFMLLVAMAPSMASAQPQPLDRIVAVVNKDAIMQSRLEDRVTQVRRQMASR
CCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NVPAPNEADLRRQVLDRMILEQIQLQMAERANLSIDDTQLNATVRGIAEDNGMSMDEFAD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHH
ALEEDGMSLASMREQVRREMLLRQVQQSQVASRVNVTDREVERYLDQQGETADTAYHLAH
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHH
ILVSVPESPTPEQVEQAQAKVRDLYRQLQNGANFAQLATAESDGQQALSGGDLGWRRGDQ
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHCCCCCCCCCCCC
LPSLFADVVPTLSNGEVSEPIRSPSGFHLVKLIDTRGQQGEQKRVVTENRVRHILIGTNP
HHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHCCCCEEEECCCC
NRNDQQAEALARDIRQRIANGESFAALAQEYSDDDGSALDGGELGWTRPGQMVPAFEDAV
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
KALDVGELSQPVRSRFGYHVIELEDRRRQDVTRDAQREQIRQTLFQRKVSDEMEAWTQEI
HHHCHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSGAYIDNRLEDGRQ
HCCCCHHHHHCCCCC
>Mature Secondary Structure
MRLRSFAFLGFMLLVAMAPSMASAQPQPLDRIVAVVNKDAIMQSRLEDRVTQVRRQMASR
CCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NVPAPNEADLRRQVLDRMILEQIQLQMAERANLSIDDTQLNATVRGIAEDNGMSMDEFAD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHH
ALEEDGMSLASMREQVRREMLLRQVQQSQVASRVNVTDREVERYLDQQGETADTAYHLAH
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHH
ILVSVPESPTPEQVEQAQAKVRDLYRQLQNGANFAQLATAESDGQQALSGGDLGWRRGDQ
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHCCCCCCCCCCCC
LPSLFADVVPTLSNGEVSEPIRSPSGFHLVKLIDTRGQQGEQKRVVTENRVRHILIGTNP
HHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHCCCCEEEECCCC
NRNDQQAEALARDIRQRIANGESFAALAQEYSDDDGSALDGGELGWTRPGQMVPAFEDAV
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
KALDVGELSQPVRSRFGYHVIELEDRRRQDVTRDAQREQIRQTLFQRKVSDEMEAWTQEI
HHHCHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSGAYIDNRLEDGRQ
HCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA