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The map label for this gene is lptD

Identifier: 92113045

GI number: 92113045

Start: 1030015

End: 1032480

Strand: Direct

Name: lptD

Synonym: Csal_0917

Alternate gene names: 92113045

Gene position: 1030015-1032480 (Clockwise)

Preceding gene: 92113040

Following gene: 92113046

Centisome position: 27.86

GC content: 65.29

Gene sequence:

>2466_bases
ATGGGCAAGCGACTCTTCTGGACTGCCCTCTCAGGCTTGATGGTGAGCGCTGCCCACGCGGCGCCTCCCGCCCCCCTGCC
CGCGCAGCAGCTCGATTGGCAACCCTGGGGCGACCAGGCGCCGAATGGCGCGCTGTGCAGCGGACGTTACGTCGAACCGG
GCTATCGGTTGTCCGCCGGTGATACGCCCCGGCAAGTGCGCACCGATTCCGCTACCGCCGCCTACGGCGATGGCGGCGCC
ACCGTGCTCGCCGGCGAGGTGGTGCTGCGCCGCGACGATACCCAGCTCGAGGCGCCTCGCGTGCGGGTCAACGCGGAGCG
CGATCGAGCCTTCGCCGAAGGCCCGACGGCGGTTCGCTATCCCGGCCTGCTGGTGCGTGGCGGTGACGCGAGCATGGCGC
TGGACGGCGATGCCGCGCAAGTCGACAACGCCCACTACGTGATCCACGAGCAACGCGTGCGCGGCGATGCGATCGAGCTG
CAGCGTCTGCCGGATGGCCGCTACCGTCTCGACGATGCCAGCTTCACCACCTGCGAACCGGGGAACCGCCTGTGGCGCAT
GGTGGGCAGTGACGTGACCCTGGATCGCGCCGAAGGGTTCGGTACCGCCACGCACGCACGCCTGGAAATGGGCGATGTGC
CGGTCTTCTACTGGCCCTGGCTGCGCTTTCCCATCGACGACCGCCGGCAAAGCGGTTTTCTGTGGCCGACGCTCGGCTTC
TCGGGCGATGGACTGGATTATACCCAGCCTTATTACCTCAACCTGGCGCCCAACTACGACGCCACCCTCTCGCCGCGCTG
GATGAGCGAGCATGGGACCATGCTGGGCGGCGAATTCCGCTATCTGTTCGGCAGCGACCAGGGCACCATCGAGGGGGCGT
ACCTGGCCAGCGACAAGGGCGGCGCCAGCGACAACCCCAACGATCCCGACGATGCCTTCGAGGATGAGTCGCGCTGGTAC
ATCGACTATCGCCATGCGGGGCGTTTCTCGCCGCGCCTGGACTATCAGCTGGCCTACGGGGCGGCGAGCGACGGTCGTTA
CTTCGATGACTTCGGGCGCGATTTCGCCGAGCAGGATACCGATCATCTGCTGCGCCTGGCACGTACGACCTATCGCGGCG
ATACCTGGCGACTGGACGCGCGCGCGCAGGGCTACCAGAAGCTCGATTACCCACTCGACGAGGACGACAAGCCGTTCTAC
CGCCTGCCGAGCCTGAGCGCCGACGCCCGCTGGCGCCAGGACAGCGGCTTCTATCAGGAGTGGAATTCCAACGCGACCTA
TTTCTGGCGCGATCTCCACGGCGTCGACAGCCAGGGACGCTGGACGGACGAGGAAACCGGCAATCGGCGCACCATTCCGC
TGCGCGAGGCCGCCAACGGGTCGCGCTTGCATCTGACGCCGGCCCTGGGATGGCGGGCCGAGCCCAGTTGGGGCTTTCTC
GAGCCGCGCGCGCAGCTCTGGCAGTCGAGCTACCAGCTCGATTACGGCAACCGGCAGACCGACCGCGACGAGAACCCCTC
GCTGGTGGCGCCGGTCCTCTCGATGGATTCGGGATTGATCTTCGAGCGCGATACCTCGCTGTTCGGTAGCGACTGGCGCC
AGACGCTGGAGCCACGGCTTTATTACGCCTATGTGCCGGAGCGCGACCAGAGCGATTTCCCCGACTTCGATACCAGCGAG
CGGGCCGTGTCCTGGGGGCAGCTGTGGTCCCCTTACCGCTTCACCGGCGCCGATCGTCTGGGAGATGTCAACAAGCTGTC
CTACGGCGCCTCGACACGCTTCCTGGAAGACGATACCGGGCGCGAGCGCCTGTCGCTGTCGGTGGGGCAGAGCAGCTACT
TCTCCGATCGCAACATCGACATGAACGGCGATCCGGACACCTTGCCGAACAAGGAACGCAACTATCAGGACTGGTACAAC
GCCACGCGGGATCGTTCGCCGGTGATCACGCAGCTCGACTGGCGGATCAGCGAACGCTGGCGTAGCCGTTATGCCTGGTT
TTACGATGCCGACCGCAGCGTGACCGAAAAGGCCTCGGCGTACCTGCAATACAACGATCCCGCGGGGCATGTGTTGAACC
TTGGCTACAGTTGGCAACTCGAAGGGTTCGAGCCGGCGGATGATGCCGAGGATCGCCTGGGCTACAACCGCGAGGATTAC
GACGTGTCCTTCGCCTACCAGGCGACGCCGAGCCTGGACCTGATCGGCCGTTTCTTGTACGACAACACCAACGACCGTGC
CATGGAGCAACTGGCGGGGGTGCAGTTCAATGACTGCTGTTCGGCGGTGCAGCTGGTCTGGCGTGAATGGATCGAGGACA
ACGACACCGCCAATACCATCGATGACGACTATACGGACCGCGGCGTATTCTTGCGTTTCGTGTTCAAGGGTCTGGGTGGC
GTCGGCCAGGAAGCCGACACCTACTTCGAGGAAGCGATTCCCGGCTACCGGGCGACGCGCTTCTGA

Upstream 100 bases:

>100_bases
GTCGCGTGGTATCTGCGTGTGTCGCGTGCCCCTCGCGAGGCAGACGCACGCGACAGGGGCTGTATAATACCGATTCCACT
CGGCAAGGACACAGAGGACC

Downstream 100 bases:

>100_bases
TCCACGCTGGCAGGTATTCACCGTCGGTGCTCGCGCCGACCACAAGACAGTAACGTAGAGAGGACTTCATGCGCTTGAGA
TCGTTCGCCTTTCTGGGCTT

Product: organic solvent tolerance protein

Products: NA

Alternate protein names: Organic solvent tolerance protein

Number of amino acids: Translated: 821; Mature: 820

Protein sequence:

>821_residues
MGKRLFWTALSGLMVSAAHAAPPAPLPAQQLDWQPWGDQAPNGALCSGRYVEPGYRLSAGDTPRQVRTDSATAAYGDGGA
TVLAGEVVLRRDDTQLEAPRVRVNAERDRAFAEGPTAVRYPGLLVRGGDASMALDGDAAQVDNAHYVIHEQRVRGDAIEL
QRLPDGRYRLDDASFTTCEPGNRLWRMVGSDVTLDRAEGFGTATHARLEMGDVPVFYWPWLRFPIDDRRQSGFLWPTLGF
SGDGLDYTQPYYLNLAPNYDATLSPRWMSEHGTMLGGEFRYLFGSDQGTIEGAYLASDKGGASDNPNDPDDAFEDESRWY
IDYRHAGRFSPRLDYQLAYGAASDGRYFDDFGRDFAEQDTDHLLRLARTTYRGDTWRLDARAQGYQKLDYPLDEDDKPFY
RLPSLSADARWRQDSGFYQEWNSNATYFWRDLHGVDSQGRWTDEETGNRRTIPLREAANGSRLHLTPALGWRAEPSWGFL
EPRAQLWQSSYQLDYGNRQTDRDENPSLVAPVLSMDSGLIFERDTSLFGSDWRQTLEPRLYYAYVPERDQSDFPDFDTSE
RAVSWGQLWSPYRFTGADRLGDVNKLSYGASTRFLEDDTGRERLSLSVGQSSYFSDRNIDMNGDPDTLPNKERNYQDWYN
ATRDRSPVITQLDWRISERWRSRYAWFYDADRSVTEKASAYLQYNDPAGHVLNLGYSWQLEGFEPADDAEDRLGYNREDY
DVSFAYQATPSLDLIGRFLYDNTNDRAMEQLAGVQFNDCCSAVQLVWREWIEDNDTANTIDDDYTDRGVFLRFVFKGLGG
VGQEADTYFEEAIPGYRATRF

Sequences:

>Translated_821_residues
MGKRLFWTALSGLMVSAAHAAPPAPLPAQQLDWQPWGDQAPNGALCSGRYVEPGYRLSAGDTPRQVRTDSATAAYGDGGA
TVLAGEVVLRRDDTQLEAPRVRVNAERDRAFAEGPTAVRYPGLLVRGGDASMALDGDAAQVDNAHYVIHEQRVRGDAIEL
QRLPDGRYRLDDASFTTCEPGNRLWRMVGSDVTLDRAEGFGTATHARLEMGDVPVFYWPWLRFPIDDRRQSGFLWPTLGF
SGDGLDYTQPYYLNLAPNYDATLSPRWMSEHGTMLGGEFRYLFGSDQGTIEGAYLASDKGGASDNPNDPDDAFEDESRWY
IDYRHAGRFSPRLDYQLAYGAASDGRYFDDFGRDFAEQDTDHLLRLARTTYRGDTWRLDARAQGYQKLDYPLDEDDKPFY
RLPSLSADARWRQDSGFYQEWNSNATYFWRDLHGVDSQGRWTDEETGNRRTIPLREAANGSRLHLTPALGWRAEPSWGFL
EPRAQLWQSSYQLDYGNRQTDRDENPSLVAPVLSMDSGLIFERDTSLFGSDWRQTLEPRLYYAYVPERDQSDFPDFDTSE
RAVSWGQLWSPYRFTGADRLGDVNKLSYGASTRFLEDDTGRERLSLSVGQSSYFSDRNIDMNGDPDTLPNKERNYQDWYN
ATRDRSPVITQLDWRISERWRSRYAWFYDADRSVTEKASAYLQYNDPAGHVLNLGYSWQLEGFEPADDAEDRLGYNREDY
DVSFAYQATPSLDLIGRFLYDNTNDRAMEQLAGVQFNDCCSAVQLVWREWIEDNDTANTIDDDYTDRGVFLRFVFKGLGG
VGQEADTYFEEAIPGYRATRF
>Mature_820_residues
GKRLFWTALSGLMVSAAHAAPPAPLPAQQLDWQPWGDQAPNGALCSGRYVEPGYRLSAGDTPRQVRTDSATAAYGDGGAT
VLAGEVVLRRDDTQLEAPRVRVNAERDRAFAEGPTAVRYPGLLVRGGDASMALDGDAAQVDNAHYVIHEQRVRGDAIELQ
RLPDGRYRLDDASFTTCEPGNRLWRMVGSDVTLDRAEGFGTATHARLEMGDVPVFYWPWLRFPIDDRRQSGFLWPTLGFS
GDGLDYTQPYYLNLAPNYDATLSPRWMSEHGTMLGGEFRYLFGSDQGTIEGAYLASDKGGASDNPNDPDDAFEDESRWYI
DYRHAGRFSPRLDYQLAYGAASDGRYFDDFGRDFAEQDTDHLLRLARTTYRGDTWRLDARAQGYQKLDYPLDEDDKPFYR
LPSLSADARWRQDSGFYQEWNSNATYFWRDLHGVDSQGRWTDEETGNRRTIPLREAANGSRLHLTPALGWRAEPSWGFLE
PRAQLWQSSYQLDYGNRQTDRDENPSLVAPVLSMDSGLIFERDTSLFGSDWRQTLEPRLYYAYVPERDQSDFPDFDTSER
AVSWGQLWSPYRFTGADRLGDVNKLSYGASTRFLEDDTGRERLSLSVGQSSYFSDRNIDMNGDPDTLPNKERNYQDWYNA
TRDRSPVITQLDWRISERWRSRYAWFYDADRSVTEKASAYLQYNDPAGHVLNLGYSWQLEGFEPADDAEDRLGYNREDYD
VSFAYQATPSLDLIGRFLYDNTNDRAMEQLAGVQFNDCCSAVQLVWREWIEDNDTANTIDDDYTDRGVFLRFVFKGLGGV
GQEADTYFEEAIPGYRATRF

Specific function: Involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis

COG id: COG1452

COG function: function code M; Organic solvent tolerance protein OstA

Gene ontology:

Cell location: Cell outer membrane

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptD family

Homologues:

Organism=Escherichia coli, GI1786239, Length=792, Percent_Identity=26.7676767676768, Blast_Score=257, Evalue=3e-69,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): LPTD_CHRSD (Q1QZ34)

Other databases:

- EMBL:   CP000285
- RefSeq:   YP_572973.1
- STRING:   Q1QZ34
- GeneID:   4027424
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_0917
- NMPDR:   fig|290398.4.peg.909
- eggNOG:   COG1452
- OMA:   TPYYWNI
- BioCyc:   CSAL290398:CSAL_0917-MONOMER
- HAMAP:   MF_01411
- InterPro:   IPR020889
- InterPro:   IPR005653
- InterPro:   IPR007543

Pfam domain/function: PF03968 OstA; PF04453 OstA_C

EC number: NA

Molecular weight: Translated: 93650; Mature: 93519

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKRLFWTALSGLMVSAAHAAPPAPLPAQQLDWQPWGDQAPNGALCSGRYVEPGYRLSAG
CCCEEHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCEECCCCEECCC
DTPRQVRTDSATAAYGDGGATVLAGEVVLRRDDTQLEAPRVRVNAERDRAFAEGPTAVRY
CCCCCEECCCCCEEECCCCCEEEEEEEEEECCCCCCCCCEEEEECHHCCHHHCCCCEEEC
PGLLVRGGDASMALDGDAAQVDNAHYVIHEQRVRGDAIELQRLPDGRYRLDDASFTTCEP
CCEEEECCCCCEEECCCHHHCCCCEEEEEHHHCCCCEEEEEECCCCCEEECCCCCCCCCC
GNRLWRMVGSDVTLDRAEGFGTATHARLEMGDVPVFYWPWLRFPIDDRRQSGFLWPTLGF
CHHHHHHHCCCCEEECCCCCCCCEEEEEEECCCCEEEECEEECCCCCCCCCCEEEEECCC
SGDGLDYTQPYYLNLAPNYDATLSPRWMSEHGTMLGGEFRYLFGSDQGTIEGAYLASDKG
CCCCCCCCCCEEEEECCCCCCCCCCCHHHCCCCEECCEEEEEEECCCCCEEEEEEECCCC
GASDNPNDPDDAFEDESRWYIDYRHAGRFSPRLDYQLAYGAASDGRYFDDFGRDFAEQDT
CCCCCCCCCCHHCCCCCEEEEEEECCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHH
DHLLRLARTTYRGDTWRLDARAQGYQKLDYPLDEDDKPFYRLPSLSADARWRQDSGFYQE
HHHHHHHHHHCCCCEEEECCHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCHHH
WNSNATYFWRDLHGVDSQGRWTDEETGNRRTIPLREAANGSRLHLTPALGWRAEPSWGFL
HCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEHHHCCCCCEEEEEECCCCCCCCCCCCC
EPRAQLWQSSYQLDYGNRQTDRDENPSLVAPVLSMDSGLIFERDTSLFGSDWRQTLEPRL
CHHHHHHHHCCEECCCCCCCCCCCCCCEEEHHHHCCCCEEEECCCCHHHHHHHHHCCCEE
YYAYVPERDQSDFPDFDTSERAVSWGQLWSPYRFTGADRLGDVNKLSYGASTRFLEDDTG
EEEECCCCCCCCCCCCCCHHHHHHHHHCCCCEEECCCHHCCCCHHCCCCCCCCEECCCCC
RERLSLSVGQSSYFSDRNIDMNGDPDTLPNKERNYQDWYNATRDRSPVITQLDWRISERW
CEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEHHHHHHHH
RSRYAWFYDADRSVTEKASAYLQYNDPAGHVLNLGYSWQLEGFEPADDAEDRLGYNREDY
HHCEEEEEECCCCHHHHCEEEEEECCCCCCEEECCEEEEECCCCCCCCHHHHCCCCCCCC
DVSFAYQATPSLDLIGRFLYDNTNDRAMEQLAGVQFNDCCSAVQLVWREWIEDNDTANTI
EEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCC
DDDYTDRGVFLRFVFKGLGGVGQEADTYFEEAIPGYRATRF
CCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
GKRLFWTALSGLMVSAAHAAPPAPLPAQQLDWQPWGDQAPNGALCSGRYVEPGYRLSAG
CCEEHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCEECCCCEECCC
DTPRQVRTDSATAAYGDGGATVLAGEVVLRRDDTQLEAPRVRVNAERDRAFAEGPTAVRY
CCCCCEECCCCCEEECCCCCEEEEEEEEEECCCCCCCCCEEEEECHHCCHHHCCCCEEEC
PGLLVRGGDASMALDGDAAQVDNAHYVIHEQRVRGDAIELQRLPDGRYRLDDASFTTCEP
CCEEEECCCCCEEECCCHHHCCCCEEEEEHHHCCCCEEEEEECCCCCEEECCCCCCCCCC
GNRLWRMVGSDVTLDRAEGFGTATHARLEMGDVPVFYWPWLRFPIDDRRQSGFLWPTLGF
CHHHHHHHCCCCEEECCCCCCCCEEEEEEECCCCEEEECEEECCCCCCCCCCEEEEECCC
SGDGLDYTQPYYLNLAPNYDATLSPRWMSEHGTMLGGEFRYLFGSDQGTIEGAYLASDKG
CCCCCCCCCCEEEEECCCCCCCCCCCHHHCCCCEECCEEEEEEECCCCCEEEEEEECCCC
GASDNPNDPDDAFEDESRWYIDYRHAGRFSPRLDYQLAYGAASDGRYFDDFGRDFAEQDT
CCCCCCCCCCHHCCCCCEEEEEEECCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHH
DHLLRLARTTYRGDTWRLDARAQGYQKLDYPLDEDDKPFYRLPSLSADARWRQDSGFYQE
HHHHHHHHHHCCCCEEEECCHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCHHH
WNSNATYFWRDLHGVDSQGRWTDEETGNRRTIPLREAANGSRLHLTPALGWRAEPSWGFL
HCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEHHHCCCCCEEEEEECCCCCCCCCCCCC
EPRAQLWQSSYQLDYGNRQTDRDENPSLVAPVLSMDSGLIFERDTSLFGSDWRQTLEPRL
CHHHHHHHHCCEECCCCCCCCCCCCCCEEEHHHHCCCCEEEECCCCHHHHHHHHHCCCEE
YYAYVPERDQSDFPDFDTSERAVSWGQLWSPYRFTGADRLGDVNKLSYGASTRFLEDDTG
EEEECCCCCCCCCCCCCCHHHHHHHHHCCCCEEECCCHHCCCCHHCCCCCCCCEECCCCC
RERLSLSVGQSSYFSDRNIDMNGDPDTLPNKERNYQDWYNATRDRSPVITQLDWRISERW
CEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEHHHHHHHH
RSRYAWFYDADRSVTEKASAYLQYNDPAGHVLNLGYSWQLEGFEPADDAEDRLGYNREDY
HHCEEEEEECCCCHHHHCEEEEEECCCCCCEEECCEEEEECCCCCCCCHHHHCCCCCCCC
DVSFAYQATPSLDLIGRFLYDNTNDRAMEQLAGVQFNDCCSAVQLVWREWIEDNDTANTI
EEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCC
DDDYTDRGVFLRFVFKGLGGVGQEADTYFEEAIPGYRATRF
CCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA