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The map label for this gene is rstA [H]

Identifier: 92112801

GI number: 92112801

Start: 750523

End: 751242

Strand: Direct

Name: rstA [H]

Synonym: Csal_0669

Alternate gene names: 92112801

Gene position: 750523-751242 (Clockwise)

Preceding gene: 92112797

Following gene: 92112802

Centisome position: 20.3

GC content: 61.81

Gene sequence:

>720_bases
ATGGATGACAGCTTGGACAGCAGCAAACATCACGATCACGTCCTGATCATAGAGGACGACGAGCGGCTGGCGCACTTGAC
GCGCGAATATCTCGAGGCCAACGAGTTCCGGGTCGACCTGGAATACGACGGCGCGCGTGCCGTCGAACGCATCCTCGATG
AACAGCCGGACATAGTGATTCTCGACCTCATGCTACCCGGTGAGGATGGCCTTTCCATCTGCCGCCGGGTACGCGGCCAT
TACGCCGGCCCTATCCTCATGTTGACCGCGCGTACCGATGACATGGACCAGGTCCTGGGGCTCGAAATGGGGGCGGACGA
CTACGTGCCCAAACCCGTTCAGCCGCGTGTCCTGCTGGCGCGCATGCGAGCCTTGCTGCGGCGCGCCGATACACTGGATG
CAGCCAGCGGGGCCACACGACTGACCTTCGGCAATCTGCTCATCGATAGCGCCACCCGCGAAGCATGGCTCGACGACGAG
CGCATCGACCTGACCAGCGCCGAGTTCGATCTGTTGTGGCTGCTGGCCGACAATGCGGGACGCGTGCTGACCCGGGAGGA
AATCTTCTCGCAGTTGCGGGGGATCAAGTACGACGGTCAGGATCGTTCGATCGACGTGCGCGTATCGCGAATCCGGCCCA
AGATCGGCGACGATCCCAATCATCCGCACCGGATCAAGACCGTGCGCAGCAAGGGCTATCTTTTCGTCAGGGATAGCTGA

Upstream 100 bases:

>100_bases
GACAGACAAGAAAGGCGCGCTAGACAATAAAAAAGAGGCGAAAGGAACTCGCACGACAAGGCCGAAGGTAGGCAGGGCTT
CATGGCACCAATGCAAAGGG

Downstream 100 bases:

>100_bases
CGTTGATCCGGCGCACACTGTCGGATAGCACCTTCCTGCGTGTGTATGCGCTATTGCTGCTCGCGCTGGTGCTGACCTTC
GGGCTGGCCCTGCTCGGCTA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MDDSLDSSKHHDHVLIIEDDERLAHLTREYLEANEFRVDLEYDGARAVERILDEQPDIVILDLMLPGEDGLSICRRVRGH
YAGPILMLTARTDDMDQVLGLEMGADDYVPKPVQPRVLLARMRALLRRADTLDAASGATRLTFGNLLIDSATREAWLDDE
RIDLTSAEFDLLWLLADNAGRVLTREEIFSQLRGIKYDGQDRSIDVRVSRIRPKIGDDPNHPHRIKTVRSKGYLFVRDS

Sequences:

>Translated_239_residues
MDDSLDSSKHHDHVLIIEDDERLAHLTREYLEANEFRVDLEYDGARAVERILDEQPDIVILDLMLPGEDGLSICRRVRGH
YAGPILMLTARTDDMDQVLGLEMGADDYVPKPVQPRVLLARMRALLRRADTLDAASGATRLTFGNLLIDSATREAWLDDE
RIDLTSAEFDLLWLLADNAGRVLTREEIFSQLRGIKYDGQDRSIDVRVSRIRPKIGDDPNHPHRIKTVRSKGYLFVRDS
>Mature_239_residues
MDDSLDSSKHHDHVLIIEDDERLAHLTREYLEANEFRVDLEYDGARAVERILDEQPDIVILDLMLPGEDGLSICRRVRGH
YAGPILMLTARTDDMDQVLGLEMGADDYVPKPVQPRVLLARMRALLRRADTLDAASGATRLTFGNLLIDSATREAWLDDE
RIDLTSAEFDLLWLLADNAGRVLTREEIFSQLRGIKYDGQDRSIDVRVSRIRPKIGDDPNHPHRIKTVRSKGYLFVRDS

Specific function: Member of the two-component regulatory system rstB/rstA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=45.6896551724138, Blast_Score=191, Evalue=4e-50,
Organism=Escherichia coli, GI1789809, Length=235, Percent_Identity=42.9787234042553, Blast_Score=180, Evalue=9e-47,
Organism=Escherichia coli, GI2367329, Length=232, Percent_Identity=37.0689655172414, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=37.6681614349776, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1788394, Length=232, Percent_Identity=35.3448275862069, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=39.2857142857143, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=32.4675324675325, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=34.070796460177, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=31.1111111111111, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=37.0535714285714, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=33.0357142857143, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1790552, Length=227, Percent_Identity=34.8017621145374, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=31.304347826087, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=37.3873873873874, Blast_Score=110, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27258; Mature: 27258

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDSLDSSKHHDHVLIIEDDERLAHLTREYLEANEFRVDLEYDGARAVERILDEQPDIVI
CCCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHCCCCCEEE
LDLMLPGEDGLSICRRVRGHYAGPILMLTARTDDMDQVLGLEMGADDYVPKPVQPRVLLA
EEEEECCCHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHCCCCCCCCCCCCCCHHHHHH
RMRALLRRADTLDAASGATRLTFGNLLIDSATREAWLDDERIDLTSAEFDLLWLLADNAG
HHHHHHHHHCCCCCCCCCEEEEECCEEEECCHHHHHCCCCCEEEECCCEEEEEEEECCCC
RVLTREEIFSQLRGIKYDGQDRSIDVRVSRIRPKIGDDPNHPHRIKTVRSKGYLFVRDS
CEEEHHHHHHHHCCCEECCCCCEEEEEEEEECCCCCCCCCCCHHEEEEECCCEEEEECC
>Mature Secondary Structure
MDDSLDSSKHHDHVLIIEDDERLAHLTREYLEANEFRVDLEYDGARAVERILDEQPDIVI
CCCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHCCCCCEEE
LDLMLPGEDGLSICRRVRGHYAGPILMLTARTDDMDQVLGLEMGADDYVPKPVQPRVLLA
EEEEECCCHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHCCCCCCCCCCCCCCHHHHHH
RMRALLRRADTLDAASGATRLTFGNLLIDSATREAWLDDERIDLTSAEFDLLWLLADNAG
HHHHHHHHHCCCCCCCCCEEEEECCEEEECCHHHHHCCCCCEEEECCCEEEEEEEECCCC
RVLTREEIFSQLRGIKYDGQDRSIDVRVSRIRPKIGDDPNHPHRIKTVRSKGYLFVRDS
CEEEHHHHHHHHCCCEECCCCCEEEEEEEEECCCCCCCCCCCHHEEEEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 1495392 [H]