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The map label for this gene is rstB [H]

Identifier: 92112802

GI number: 92112802

Start: 751245

End: 752897

Strand: Direct

Name: rstB [H]

Synonym: Csal_0670

Alternate gene names: 92112802

Gene position: 751245-752897 (Clockwise)

Preceding gene: 92112801

Following gene: 92112804

Centisome position: 20.32

GC content: 68.06

Gene sequence:

>1653_bases
TTGATCCGGCGCACACTGTCGGATAGCACCTTCCTGCGTGTGTATGCGCTATTGCTGCTCGCGCTGGTGCTGACCTTCGG
GCTGGCCCTGCTCGGCTATCTCGTGGTCGATCAAGTGCGCCAGGAGAACTACCGTGAACGCCTCGCCAGCGGGCCGATGC
AGGTGCTCGCGCAACTCGCCGCCGAGCAGCCGGCCGCGGAACGCGACGAGTGGCTGGCGTCGATGTCGTCGACCCTGGGC
GTGCCCATGACACTGCGACCCATGAACGGTGTCGCGTTGAGCTATTTCGAGCGTTCTCGCCTCGATGAGGGGCGCCCCCT
GATCGAGCGTCACGACTCGGCCTGGTCGGCATTGCGCCGCCTGCCGGACACGGACTGGCTGTTGGAAGTGCGTGTCGGGG
CGCTCAAGGAGATGCAGTTGCGGGGCGCCACCGAGGCGTTGCGGACCTGGCTCAGCGGGGTCTCGGAAGACGAGAGTGCC
GCGCGCCTGGCGCGGCTCAAGCGTGCCTTCAAGATTCCCCTGGGGGTGGCGCCGGAGCCACCGTCGGGGGTCGACCCCAT
TCAACAGGCGCGGCTCGAGGGAGGCGAAGTCGTCGTGCGTCTCGAGCCGGGGCTCGGGGTGCTCTACGTGCATGCGCGTC
TGGGATCGGACCGCTGGCTGACGATCGGGCCGATTCCTTCCTTCGAACCGATGCCGGTATCGCTGGCGCTCGCCTTGCTG
GGGATCGTGCTGCTGGTGCTGGCCGGCACCATCTATCTCGTGGTGCGCGGCGTGGAGGGACGCGTGGAGCGTCTGGAGCG
GGCGGCGACACGCATCGCCGGGGGCCACCTGGATACCCGCGTCAAGGTGGAGAGCAGCGACTTCCTGGGGCGCCTGGGCA
TGGCGTTCAACGGCATGGCCGCCCAGGTGCAGTCGTTGCTGCGCACCCAGCAGGAAATGATTCGCGCCGTGTCCCATGAG
CTGCGTACCCCGGTGGCGCGAATTCGCTTCGCCGTGCAGATGGTCGAGGACATGACCGACGAGCCGGTGGTGCGCCGCCA
GCTGCAGGATATCGACGGCGATATCGAGGAGCTCGATCAACTGGTCGACGAGATCCTGACGTACGCCCGTCTGGGCAGCG
ACAGTGCCCAGGGCATCCAGCTCGCCACTGAAACCACCGACTGCCGGGCCATGGCACGTCGCGTGGTCGAGACGCTGGCG
CCGCTGCATCCGCACCTGACGCTGGAAGTGCTGGATGGCGAGGACGTCGACGTCGAGGCCGACCCGCGCTATCTGCAGCG
TGCGCTTTCCAACCTGGTGGCCAACGCGTGCCGGCATGCGGAAGCGCGTGTCTGGGTGCGGGTGATGCGCGACCCCCGTG
CGGTTCGTCTGGATGTCGAAGACGACGGCGCCGGGGTGCCCGAAGCCGATCGTCTGCTGATCTTCAAGCCTTTCGCGCGG
CTCGACGACAGCCGCACGCGGCGCTCCGGAGGCTACGGGCTGGGGCTGTCCATCGTGCAGAAAATCATGATCTGGCACGG
CGGTAGCGTGGTGGTCGAGCGCAGCACGGAACTCGGCGGCGCGCGCTTCAGTCTGCTGCTGTCCACCGCCGGAGTGGCCC
AGCACGAGCGGCGCCAGGGCAAGGCCAGGCCGTCGCACGGTGGCGAGGCCTGA

Upstream 100 bases:

>100_bases
TATCGCGAATCCGGCCCAAGATCGGCGACGATCCCAATCATCCGCACCGGATCAAGACCGTGCGCAGCAAGGGCTATCTT
TTCGTCAGGGATAGCTGACG

Downstream 100 bases:

>100_bases
TGCCCGGGGCGGTGCCTACGCCGGCTTGATGCCCGCGAGGACGGCGAAGGACGTTTCCCTCGCGGTGCGCAGAAAATCCT
CCATCCACGGGGCGTCGCGG

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 550; Mature: 550

Protein sequence:

>550_residues
MIRRTLSDSTFLRVYALLLLALVLTFGLALLGYLVVDQVRQENYRERLASGPMQVLAQLAAEQPAAERDEWLASMSSTLG
VPMTLRPMNGVALSYFERSRLDEGRPLIERHDSAWSALRRLPDTDWLLEVRVGALKEMQLRGATEALRTWLSGVSEDESA
ARLARLKRAFKIPLGVAPEPPSGVDPIQQARLEGGEVVVRLEPGLGVLYVHARLGSDRWLTIGPIPSFEPMPVSLALALL
GIVLLVLAGTIYLVVRGVEGRVERLERAATRIAGGHLDTRVKVESSDFLGRLGMAFNGMAAQVQSLLRTQQEMIRAVSHE
LRTPVARIRFAVQMVEDMTDEPVVRRQLQDIDGDIEELDQLVDEILTYARLGSDSAQGIQLATETTDCRAMARRVVETLA
PLHPHLTLEVLDGEDVDVEADPRYLQRALSNLVANACRHAEARVWVRVMRDPRAVRLDVEDDGAGVPEADRLLIFKPFAR
LDDSRTRRSGGYGLGLSIVQKIMIWHGGSVVVERSTELGGARFSLLLSTAGVAQHERRQGKARPSHGGEA

Sequences:

>Translated_550_residues
MIRRTLSDSTFLRVYALLLLALVLTFGLALLGYLVVDQVRQENYRERLASGPMQVLAQLAAEQPAAERDEWLASMSSTLG
VPMTLRPMNGVALSYFERSRLDEGRPLIERHDSAWSALRRLPDTDWLLEVRVGALKEMQLRGATEALRTWLSGVSEDESA
ARLARLKRAFKIPLGVAPEPPSGVDPIQQARLEGGEVVVRLEPGLGVLYVHARLGSDRWLTIGPIPSFEPMPVSLALALL
GIVLLVLAGTIYLVVRGVEGRVERLERAATRIAGGHLDTRVKVESSDFLGRLGMAFNGMAAQVQSLLRTQQEMIRAVSHE
LRTPVARIRFAVQMVEDMTDEPVVRRQLQDIDGDIEELDQLVDEILTYARLGSDSAQGIQLATETTDCRAMARRVVETLA
PLHPHLTLEVLDGEDVDVEADPRYLQRALSNLVANACRHAEARVWVRVMRDPRAVRLDVEDDGAGVPEADRLLIFKPFAR
LDDSRTRRSGGYGLGLSIVQKIMIWHGGSVVVERSTELGGARFSLLLSTAGVAQHERRQGKARPSHGGEA
>Mature_550_residues
MIRRTLSDSTFLRVYALLLLALVLTFGLALLGYLVVDQVRQENYRERLASGPMQVLAQLAAEQPAAERDEWLASMSSTLG
VPMTLRPMNGVALSYFERSRLDEGRPLIERHDSAWSALRRLPDTDWLLEVRVGALKEMQLRGATEALRTWLSGVSEDESA
ARLARLKRAFKIPLGVAPEPPSGVDPIQQARLEGGEVVVRLEPGLGVLYVHARLGSDRWLTIGPIPSFEPMPVSLALALL
GIVLLVLAGTIYLVVRGVEGRVERLERAATRIAGGHLDTRVKVESSDFLGRLGMAFNGMAAQVQSLLRTQQEMIRAVSHE
LRTPVARIRFAVQMVEDMTDEPVVRRQLQDIDGDIEELDQLVDEILTYARLGSDSAQGIQLATETTDCRAMARRVVETLA
PLHPHLTLEVLDGEDVDVEADPRYLQRALSNLVANACRHAEARVWVRVMRDPRAVRLDVEDDGAGVPEADRLLIFKPFAR
LDDSRTRRSGGYGLGLSIVQKIMIWHGGSVVVERSTELGGARFSLLLSTAGVAQHERRQGKARPSHGGEA

Specific function: Member of the two-component regulatory system rstB/rstA. RstB functions as a membrane-associated protein kinase that phosphorylates rstA (Potential) [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787894, Length=392, Percent_Identity=31.8877551020408, Blast_Score=176, Evalue=4e-45,
Organism=Escherichia coli, GI1790346, Length=270, Percent_Identity=31.4814814814815, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1789808, Length=324, Percent_Identity=29.0123456790123, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1786600, Length=241, Percent_Identity=29.8755186721992, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1788393, Length=284, Percent_Identity=27.8169014084507, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1786783, Length=383, Percent_Identity=24.2819843342037, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI87082128, Length=284, Percent_Identity=26.4084507042254, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1789149, Length=337, Percent_Identity=25.2225519287834, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1790861, Length=299, Percent_Identity=30.4347826086957, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790551, Length=234, Percent_Identity=29.0598290598291, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788549, Length=225, Percent_Identity=27.1111111111111, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI145693157, Length=269, Percent_Identity=24.5353159851301, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87081816, Length=345, Percent_Identity=25.5072463768116, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1788279, Length=298, Percent_Identity=28.1879194630872, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1786912, Length=238, Percent_Identity=28.1512605042017, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 60740; Mature: 60740

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRRTLSDSTFLRVYALLLLALVLTFGLALLGYLVVDQVRQENYRERLASGPMQVLAQLA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
AEQPAAERDEWLASMSSTLGVPMTLRPMNGVALSYFERSRLDEGRPLIERHDSAWSALRR
HCCCCCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHCCCCCCCHHHHCCHHHHHHHH
LPDTDWLLEVRVGALKEMQLRGATEALRTWLSGVSEDESAARLARLKRAFKIPLGVAPEP
CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
PSGVDPIQQARLEGGEVVVRLEPGLGVLYVHARLGSDRWLTIGPIPSFEPMPVSLALALL
CCCCCHHHHHHCCCCCEEEEECCCCCEEEEEEECCCCCEEEECCCCCCCCCHHHHHHHHH
GIVLLVLAGTIYLVVRGVEGRVERLERAATRIAGGHLDTRVKVESSDFLGRLGMAFNGMA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHCHHH
AQVQSLLRTQQEMIRAVSHELRTPVARIRFAVQMVEDMTDEPVVRRQLQDIDGDIEELDQ
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHH
LVDEILTYARLGSDSAQGIQLATETTDCRAMARRVVETLAPLHPHLTLEVLDGEDVDVEA
HHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCC
DPRYLQRALSNLVANACRHAEARVWVRVMRDPRAVRLDVEDDGAGVPEADRLLIFKPFAR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEEECCHHH
LDDSRTRRSGGYGLGLSIVQKIMIWHGGSVVVERSTELGGARFSLLLSTAGVAQHERRQG
CCCHHHHCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCC
KARPSHGGEA
CCCCCCCCCC
>Mature Secondary Structure
MIRRTLSDSTFLRVYALLLLALVLTFGLALLGYLVVDQVRQENYRERLASGPMQVLAQLA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
AEQPAAERDEWLASMSSTLGVPMTLRPMNGVALSYFERSRLDEGRPLIERHDSAWSALRR
HCCCCCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHCCCCCCCHHHHCCHHHHHHHH
LPDTDWLLEVRVGALKEMQLRGATEALRTWLSGVSEDESAARLARLKRAFKIPLGVAPEP
CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
PSGVDPIQQARLEGGEVVVRLEPGLGVLYVHARLGSDRWLTIGPIPSFEPMPVSLALALL
CCCCCHHHHHHCCCCCEEEEECCCCCEEEEEEECCCCCEEEECCCCCCCCCHHHHHHHHH
GIVLLVLAGTIYLVVRGVEGRVERLERAATRIAGGHLDTRVKVESSDFLGRLGMAFNGMA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHCHHH
AQVQSLLRTQQEMIRAVSHELRTPVARIRFAVQMVEDMTDEPVVRRQLQDIDGDIEELDQ
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHH
LVDEILTYARLGSDSAQGIQLATETTDCRAMARRVVETLAPLHPHLTLEVLDGEDVDVEA
HHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCC
DPRYLQRALSNLVANACRHAEARVWVRVMRDPRAVRLDVEDDGAGVPEADRLLIFKPFAR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEEECCHHH
LDDSRTRRSGGYGLGLSIVQKIMIWHGGSVVVERSTELGGARFSLLLSTAGVAQHERRQG
CCCHHHHCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCC
KARPSHGGEA
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 2646639; 1925016; 1495392 [H]