| Definition | Chromohalobacter salexigens DSM 3043 chromosome, complete genome. |
|---|---|
| Accession | NC_007963 |
| Length | 3,696,649 |
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The map label for this gene is polS [H]
Identifier: 92112771
GI number: 92112771
Start: 715640
End: 716425
Strand: Direct
Name: polS [H]
Synonym: Csal_0638
Alternate gene names: 92112771
Gene position: 715640-716425 (Clockwise)
Preceding gene: 92112770
Following gene: 92112772
Centisome position: 19.36
GC content: 67.94
Gene sequence:
>786_bases ATGAAACTCGACAAGCGAACGGCAGTGGTGACCGGTGGCGCGCGCGGGATCGGCCTGGCGATCGTCAAGGGCTATCTGCG GGAAGGGGCGCGCGTGGCGATCGCCGATATCGACACCGACGCCGCCGAGCAGGCGGTCGCCGAGATTCGGGCCGAGGTCG ACGAGGCGCCGGTGATGGCGGTGCGGCTCGACGTGGCCGACGCCGACTCGCGCCAGGCGATGATCGCGGCCGTCGAGGCG CGTTTCGGCGGTATCGACATCCTCGTCAACAATGCGGCGGTATTCGACATGGCCCCGGTGCTCGAGGTCAGCGAGGCCAG CTATGACCGGCAATTCGGCATCAACGTCAAGGGGACCTTCTTCACCCTGCAGGCGGTGGCGGCGCATATGGTCGAGCGCG GCCAGGGCGGCAAGATCATCAACATGGCCTCCCAGGCCGGGCGCCGCGGCGAGCCCCTGGTCAGCATGTACTGCGCCTCC AAGGCCGCGGTGATCAGCCTCACCCAGTCCTGCGGCCTCGCCCTGATCAAGCACCGCATCAACGTCAACGGCATCGCCCC CGGGGTGGTCGACACCCCCATGTGGGACGAGGTCGATGCCTTGTTCGCGCGCTACGAGAACCGCCCGGCCGGCGAGAAGA AGCGCCTGGTCGGCGAGGCGGTGCCCTATGGTCGCATGGGGCGTCCCGAAGACCATGTCGGCGCGGCGGTGTTCCTGGCT TCCGCCGACAGCGATTACGTGGTGGCACAGACGCTGAACGTCGATGGCGGCAACTGGATGAGCTGA
Upstream 100 bases:
>100_bases GCGAGCGTCACGCCGTGCGCTGAAGACCGCCGGGGGGATATGGCCGACGGCCCGAAGCTGGCGCTTCATCATGACTTCAC TCGAACAAGGAACCACAGCG
Downstream 100 bases:
>100_bases TCATGAGCGCAGACCTGCCTCGCTTCGATATCGTCACCGCCGGCGAGCTGCTCGCCGAATTCGTCGCCGAACGACCCGGC CAGCGCTTCGACGTGCCGGG
Product: sorbitol dehydrogenase
Products: NA
Alternate protein names: L-iditol 2-dehydrogenase; Polyol dehydrogenase [H]
Number of amino acids: Translated: 261; Mature: 261
Protein sequence:
>261_residues MKLDKRTAVVTGGARGIGLAIVKGYLREGARVAIADIDTDAAEQAVAEIRAEVDEAPVMAVRLDVADADSRQAMIAAVEA RFGGIDILVNNAAVFDMAPVLEVSEASYDRQFGINVKGTFFTLQAVAAHMVERGQGGKIINMASQAGRRGEPLVSMYCAS KAAVISLTQSCGLALIKHRINVNGIAPGVVDTPMWDEVDALFARYENRPAGEKKRLVGEAVPYGRMGRPEDHVGAAVFLA SADSDYVVAQTLNVDGGNWMS
Sequences:
>Translated_261_residues MKLDKRTAVVTGGARGIGLAIVKGYLREGARVAIADIDTDAAEQAVAEIRAEVDEAPVMAVRLDVADADSRQAMIAAVEA RFGGIDILVNNAAVFDMAPVLEVSEASYDRQFGINVKGTFFTLQAVAAHMVERGQGGKIINMASQAGRRGEPLVSMYCAS KAAVISLTQSCGLALIKHRINVNGIAPGVVDTPMWDEVDALFARYENRPAGEKKRLVGEAVPYGRMGRPEDHVGAAVFLA SADSDYVVAQTLNVDGGNWMS >Mature_261_residues MKLDKRTAVVTGGARGIGLAIVKGYLREGARVAIADIDTDAAEQAVAEIRAEVDEAPVMAVRLDVADADSRQAMIAAVEA RFGGIDILVNNAAVFDMAPVLEVSEASYDRQFGINVKGTFFTLQAVAAHMVERGQGGKIINMASQAGRRGEPLVSMYCAS KAAVISLTQSCGLALIKHRINVNGIAPGVVDTPMWDEVDALFARYENRPAGEKKRLVGEAVPYGRMGRPEDHVGAAVFLA SADSDYVVAQTLNVDGGNWMS
Specific function: Catalyzes the oxidation of D-glucitol (sorbitol) to D- fructose, galactitol to D-tagatose and of L-iditol [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=265, Percent_Identity=33.9622641509434, Blast_Score=125, Evalue=4e-29, Organism=Homo sapiens, GI7705925, Length=262, Percent_Identity=33.206106870229, Blast_Score=122, Evalue=4e-28, Organism=Homo sapiens, GI32483357, Length=259, Percent_Identity=32.8185328185328, Blast_Score=122, Evalue=4e-28, Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=28.8461538461538, Blast_Score=106, Evalue=2e-23, Organism=Homo sapiens, GI31542939, Length=239, Percent_Identity=30.1255230125523, Blast_Score=103, Evalue=2e-22, Organism=Homo sapiens, GI126723750, Length=262, Percent_Identity=29.0076335877863, Blast_Score=99, Evalue=5e-21, Organism=Homo sapiens, GI59889578, Length=238, Percent_Identity=32.7731092436975, Blast_Score=97, Evalue=2e-20, Organism=Homo sapiens, GI5031737, Length=255, Percent_Identity=30.1960784313725, Blast_Score=96, Evalue=5e-20, Organism=Homo sapiens, GI40254992, Length=255, Percent_Identity=28.2352941176471, Blast_Score=95, Evalue=6e-20, Organism=Homo sapiens, GI224922801, Length=174, Percent_Identity=32.7586206896552, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI66933014, Length=261, Percent_Identity=30.6513409961686, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI10190704, Length=261, Percent_Identity=27.2030651340996, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI33667109, Length=193, Percent_Identity=32.1243523316062, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI126723191, Length=184, Percent_Identity=32.0652173913043, Blast_Score=81, Evalue=8e-16, Organism=Homo sapiens, GI109715829, Length=243, Percent_Identity=27.9835390946502, Blast_Score=80, Evalue=3e-15, Organism=Homo sapiens, GI4503817, Length=226, Percent_Identity=27.8761061946903, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI4758504, Length=265, Percent_Identity=25.6603773584906, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI7706318, Length=212, Percent_Identity=29.2452830188679, Blast_Score=75, Evalue=8e-14, Organism=Homo sapiens, GI210032110, Length=189, Percent_Identity=27.5132275132275, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI4504505, Length=200, Percent_Identity=29, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI4503301, Length=230, Percent_Identity=24.3478260869565, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI225579078, Length=202, Percent_Identity=28.7128712871287, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI142976729, Length=187, Percent_Identity=24.5989304812834, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI166795268, Length=206, Percent_Identity=27.6699029126214, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI83715985, Length=262, Percent_Identity=24.4274809160305, Blast_Score=65, Evalue=6e-11, Organism=Homo sapiens, GI20149619, Length=190, Percent_Identity=26.8421052631579, Blast_Score=65, Evalue=7e-11, Organism=Homo sapiens, GI186928839, Length=206, Percent_Identity=26.6990291262136, Blast_Score=65, Evalue=9e-11, Organism=Escherichia coli, GI1790717, Length=259, Percent_Identity=35.1351351351351, Blast_Score=140, Evalue=9e-35, Organism=Escherichia coli, GI1789208, Length=263, Percent_Identity=37.2623574144487, Blast_Score=139, Evalue=3e-34, Organism=Escherichia coli, GI87082160, Length=259, Percent_Identity=33.976833976834, Blast_Score=116, Evalue=2e-27, Organism=Escherichia coli, GI87082100, Length=267, Percent_Identity=33.7078651685393, Blast_Score=115, Evalue=3e-27, Organism=Escherichia coli, GI1788459, Length=260, Percent_Identity=31.1538461538462, Blast_Score=114, Evalue=9e-27, Organism=Escherichia coli, GI1789057, Length=260, Percent_Identity=30.7692307692308, Blast_Score=112, Evalue=2e-26, Organism=Escherichia coli, GI1787905, Length=257, Percent_Identity=33.852140077821, Blast_Score=108, Evalue=5e-25, Organism=Escherichia coli, GI1787335, Length=260, Percent_Identity=29.6153846153846, Blast_Score=102, Evalue=2e-23, Organism=Escherichia coli, GI1786812, Length=262, Percent_Identity=30.9160305343511, Blast_Score=102, Evalue=4e-23, Organism=Escherichia coli, GI1789378, Length=265, Percent_Identity=27.9245283018868, Blast_Score=94, Evalue=9e-21, Organism=Escherichia coli, GI2367175, Length=256, Percent_Identity=29.6875, Blast_Score=85, Evalue=4e-18, Organism=Escherichia coli, GI2367365, Length=253, Percent_Identity=29.6442687747036, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1787820, Length=183, Percent_Identity=31.1475409836066, Blast_Score=74, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17561402, Length=257, Percent_Identity=31.1284046692607, Blast_Score=127, Evalue=5e-30, Organism=Caenorhabditis elegans, GI25147288, Length=260, Percent_Identity=33.0769230769231, Blast_Score=115, Evalue=2e-26, Organism=Caenorhabditis elegans, GI17555706, Length=258, Percent_Identity=31.0077519379845, Blast_Score=109, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17562906, Length=266, Percent_Identity=30.8270676691729, Blast_Score=107, Evalue=6e-24, Organism=Caenorhabditis elegans, GI17562990, Length=267, Percent_Identity=28.4644194756554, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=29.6992481203008, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17559104, Length=272, Percent_Identity=30.1470588235294, Blast_Score=103, Evalue=6e-23, Organism=Caenorhabditis elegans, GI17560150, Length=271, Percent_Identity=28.4132841328413, Blast_Score=103, Evalue=6e-23, Organism=Caenorhabditis elegans, GI17560676, Length=256, Percent_Identity=29.296875, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI193204405, Length=272, Percent_Identity=29.0441176470588, Blast_Score=100, Evalue=8e-22, Organism=Caenorhabditis elegans, GI17560220, Length=273, Percent_Identity=26.3736263736264, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17562904, Length=269, Percent_Identity=28.996282527881, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17562908, Length=266, Percent_Identity=28.9473684210526, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17562910, Length=269, Percent_Identity=26.3940520446097, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI115534694, Length=260, Percent_Identity=30, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI17538480, Length=268, Percent_Identity=27.9850746268657, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI71994604, Length=258, Percent_Identity=27.1317829457364, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17551412, Length=272, Percent_Identity=27.5735294117647, Blast_Score=91, Evalue=7e-19, Organism=Caenorhabditis elegans, GI71994600, Length=257, Percent_Identity=27.2373540856031, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17563726, Length=267, Percent_Identity=28.4644194756554, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI72000259, Length=266, Percent_Identity=29.3233082706767, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17560332, Length=273, Percent_Identity=27.8388278388278, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17567345, Length=193, Percent_Identity=29.5336787564767, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17536025, Length=256, Percent_Identity=26.5625, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17561272, Length=243, Percent_Identity=27.9835390946502, Blast_Score=84, Evalue=9e-17, Organism=Caenorhabditis elegans, GI17538486, Length=267, Percent_Identity=27.3408239700375, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17536651, Length=255, Percent_Identity=27.0588235294118, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17565030, Length=271, Percent_Identity=28.0442804428044, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17508651, Length=254, Percent_Identity=29.1338582677165, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17538182, Length=266, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI193203117, Length=198, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17508895, Length=197, Percent_Identity=27.9187817258883, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17544670, Length=272, Percent_Identity=23.8970588235294, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI193203115, Length=193, Percent_Identity=27.4611398963731, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17564282, Length=214, Percent_Identity=25.7009345794392, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17568967, Length=199, Percent_Identity=27.1356783919598, Blast_Score=70, Evalue=8e-13, Organism=Caenorhabditis elegans, GI71982365, Length=143, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=4e-11, Organism=Saccharomyces cerevisiae, GI6323882, Length=195, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=3e-17, Organism=Saccharomyces cerevisiae, GI6322861, Length=197, Percent_Identity=26.3959390862944, Blast_Score=70, Evalue=2e-13, Organism=Saccharomyces cerevisiae, GI6324126, Length=257, Percent_Identity=26.4591439688716, Blast_Score=68, Evalue=1e-12, Organism=Drosophila melanogaster, GI24639444, Length=257, Percent_Identity=34.6303501945525, Blast_Score=123, Evalue=1e-28, Organism=Drosophila melanogaster, GI21355319, Length=257, Percent_Identity=31.5175097276265, Blast_Score=112, Evalue=2e-25, Organism=Drosophila melanogaster, GI23397609, Length=260, Percent_Identity=28.4615384615385, Blast_Score=95, Evalue=5e-20, Organism=Drosophila melanogaster, GI21357041, Length=259, Percent_Identity=27.7992277992278, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI24643142, Length=256, Percent_Identity=29.296875, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI24644339, Length=260, Percent_Identity=27.6923076923077, Blast_Score=86, Evalue=3e-17, Organism=Drosophila melanogaster, GI221331218, Length=199, Percent_Identity=30.6532663316583, Blast_Score=82, Evalue=5e-16, Organism=Drosophila melanogaster, GI24665243, Length=199, Percent_Identity=30.6532663316583, Blast_Score=82, Evalue=5e-16, Organism=Drosophila melanogaster, GI281364892, Length=163, Percent_Identity=32.5153374233129, Blast_Score=81, Evalue=7e-16, Organism=Drosophila melanogaster, GI28571526, Length=261, Percent_Identity=27.9693486590038, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI17737361, Length=266, Percent_Identity=27.4436090225564, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI221331216, Length=200, Percent_Identity=30.5, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI24665247, Length=200, Percent_Identity=30.5, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI24656154, Length=210, Percent_Identity=29.5238095238095, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI19922628, Length=210, Percent_Identity=29.5238095238095, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI116007236, Length=196, Percent_Identity=29.5918367346939, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI24640492, Length=191, Percent_Identity=26.1780104712042, Blast_Score=71, Evalue=9e-13, Organism=Drosophila melanogaster, GI21355631, Length=165, Percent_Identity=26.6666666666667, Blast_Score=71, Evalue=9e-13, Organism=Drosophila melanogaster, GI21358495, Length=195, Percent_Identity=27.6923076923077, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI28573296, Length=208, Percent_Identity=28.3653846153846, Blast_Score=69, Evalue=5e-12, Organism=Drosophila melanogaster, GI161076371, Length=201, Percent_Identity=28.3582089552239, Blast_Score=69, Evalue=5e-12, Organism=Drosophila melanogaster, GI24641232, Length=200, Percent_Identity=28, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI161076933, Length=190, Percent_Identity=27.8947368421053, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24584748, Length=190, Percent_Identity=27.8947368421053, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24581726, Length=181, Percent_Identity=27.0718232044199, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI18859837, Length=192, Percent_Identity=29.1666666666667, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI116007234, Length=196, Percent_Identity=29.0816326530612, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI24580925, Length=194, Percent_Identity=28.3505154639175, Blast_Score=65, Evalue=6e-11, Organism=Drosophila melanogaster, GI281364494, Length=208, Percent_Identity=26.4423076923077, Blast_Score=65, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.14 [H]
Molecular weight: Translated: 27679; Mature: 27679
Theoretical pI: Translated: 4.99; Mature: 4.99
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 3.8 %Met (Translated Protein) 4.6 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 3.8 %Met (Mature Protein) 4.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKLDKRTAVVTGGARGIGLAIVKGYLREGARVAIADIDTDAAEQAVAEIRAEVDEAPVMA CCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCCCEEE VRLDVADADSRQAMIAAVEARFGGIDILVNNAAVFDMAPVLEVSEASYDRQFGINVKGTF EEEEECCCCCCHHEEEEEHHCCCCEEEEECCEEEEECCCHHHHHCCCCCCEECCCCCCHH FTLQAVAAHMVERGQGGKIINMASQAGRRGEPLVSMYCASKAAVISLTQSCGLALIKHRI HHHHHHHHHHHHCCCCCCEEEEHHHCCCCCCCHHHHHHCCCHHEEEEHHHHHHHHHHHHC NVNGIAPGVVDTPMWDEVDALFARYENRPAGEKKRLVGEAVPYGRMGRPEDHVGAAVFLA CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEE SADSDYVVAQTLNVDGGNWMS ECCCCEEEEEEEECCCCCCCC >Mature Secondary Structure MKLDKRTAVVTGGARGIGLAIVKGYLREGARVAIADIDTDAAEQAVAEIRAEVDEAPVMA CCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCCCEEE VRLDVADADSRQAMIAAVEARFGGIDILVNNAAVFDMAPVLEVSEASYDRQFGINVKGTF EEEEECCCCCCHHEEEEEHHCCCCEEEEECCEEEEECCCHHHHHCCCCCCEECCCCCCHH FTLQAVAAHMVERGQGGKIINMASQAGRRGEPLVSMYCASKAAVISLTQSCGLALIKHRI HHHHHHHHHHHHCCCCCCEEEEHHHCCCCCCCHHHHHHCCCHHEEEEHHHHHHHHHHHHC NVNGIAPGVVDTPMWDEVDALFARYENRPAGEKKRLVGEAVPYGRMGRPEDHVGAAVFLA CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEE SADSDYVVAQTLNVDGGNWMS ECCCCEEEEEEEECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7551049 [H]