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The map label for this gene is obgE

Identifier: 92112609

GI number: 92112609

Start: 524167

End: 525354

Strand: Direct

Name: obgE

Synonym: Csal_0476

Alternate gene names: 92112609

Gene position: 524167-525354 (Clockwise)

Preceding gene: 92112608

Following gene: 92112610

Centisome position: 14.18

GC content: 66.16

Gene sequence:

>1188_bases
ATGCAGTTCGTCGACGAAGCCTCGATCATCGTGGAGGCCGGCAAGGGTGGCAATGGCTGCCTGAGTTTCCGGCGCGAGAA
GTACGTTCCCAAGGGCGGGCCGGACGGCGGCGACGGTGGGCACGGCGGCAGCGTCTACCTGATCGGTGACGAATCCCTCA
ATACGCTGATCGACTTCAAGTATCAGCGCTTCTACAAGGCACCCAACGGTCAGCCGGGACAAGGGCGCCAGATGAGCGGT
CGCAACGGCGAGGACCTGCACGTCAAGGTGCCGGTGGGGACCACGGTGATCGACGAGGACACCCTCGAGGTGATCGCCGA
CGTGACCGAGGCCGGCCAGGTCGTGCTCGTGGCCCAGGCGGGCCGCCGTGGACTGGGGAACATCCATTTCAAGTCCTCCA
CCAACCGGGCGCCGCGCAAGACCACGCCGGGCACCGAGGGGGAGCGTCGCAACCTGCGCTTCGAAATGAAGGTGATGGCC
GACGTGGGCCTGCTGGGCGTGCCCAATGCCGGCAAGTCGACCCTGATTCGTGCCGTCTCGGCGGCCAAGCCCAAGGTGGC
CAACTACCCCTTCACCACGCTGGTACCCAATCTCGGCGTGGTCAAGCTGGGGACCCACGAGCACTTCGTGATGGCCGACG
TGCCTGGCTTGATCGAGGGAGCCTCGGACGGCGCAGGCCTGGGCTTGCGCTTTCTCAAGCACCTGACCCGGACACGGTTG
CTGCTGCACGTGGTCGATGTGGCGCCGTTCGACGAGAGCGATCCCGTGGACAGCGCGCGTGCCATCGCGCATGAACTCGA
GCAGTTTTCCGCCACGCTGGCCGAACGGCCGCGCTGGCTGGTGCTCAACAAGCTCGACCTGCTCCCCGAGGAGGAGCGCC
CGTCGACGGTCGACGACATCGTCGAGCGGCTGGCGTGGTCGGGACCGGTCTACAAGATCTCCGCCATCAGTGGCGATGGC
ACCCAAGCCCTGGTGCAGGCGGCGCACCGCTGGTTGACGGAGCAGCGCCAGCTGGAAGCAGAAGACGAGACGGCCTTCGA
GCATGAGCGCGAGATGCGTCGACGCATGGAAGACGAAGCCGTGGCGCGTGCCGAGGCGCGCATGTCCCGCAAGCGCAAGC
CGGCCGAGGACGATGACGACGATTTCGACGAAGACGATTACGACGTCGAAGTGGAGTACGCGCCGTGA

Upstream 100 bases:

>100_bases
TGTCGTCTCCGCCTGAGACCACCGCGAACGATGAAGGAAAAGGCCCCGCCCAGGCGGGGCCTTTTCGTATTGGGCGGCCG
TGGCCGCCGGGAGAGTGTCC

Downstream 100 bases:

>100_bases
TGCGGCCGCAAGGAGACGTGAACCGGTGAGCGAATCGCAGTCGGCAAGCCGCGATGCCCTGCGTCGGGCGCGGCGTGTCG
TGGTCAAGATCGGAAGTGCG

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MQFVDEASIIVEAGKGGNGCLSFRREKYVPKGGPDGGDGGHGGSVYLIGDESLNTLIDFKYQRFYKAPNGQPGQGRQMSG
RNGEDLHVKVPVGTTVIDEDTLEVIADVTEAGQVVLVAQAGRRGLGNIHFKSSTNRAPRKTTPGTEGERRNLRFEMKVMA
DVGLLGVPNAGKSTLIRAVSAAKPKVANYPFTTLVPNLGVVKLGTHEHFVMADVPGLIEGASDGAGLGLRFLKHLTRTRL
LLHVVDVAPFDESDPVDSARAIAHELEQFSATLAERPRWLVLNKLDLLPEEERPSTVDDIVERLAWSGPVYKISAISGDG
TQALVQAAHRWLTEQRQLEAEDETAFEHEREMRRRMEDEAVARAEARMSRKRKPAEDDDDDFDEDDYDVEVEYAP

Sequences:

>Translated_395_residues
MQFVDEASIIVEAGKGGNGCLSFRREKYVPKGGPDGGDGGHGGSVYLIGDESLNTLIDFKYQRFYKAPNGQPGQGRQMSG
RNGEDLHVKVPVGTTVIDEDTLEVIADVTEAGQVVLVAQAGRRGLGNIHFKSSTNRAPRKTTPGTEGERRNLRFEMKVMA
DVGLLGVPNAGKSTLIRAVSAAKPKVANYPFTTLVPNLGVVKLGTHEHFVMADVPGLIEGASDGAGLGLRFLKHLTRTRL
LLHVVDVAPFDESDPVDSARAIAHELEQFSATLAERPRWLVLNKLDLLPEEERPSTVDDIVERLAWSGPVYKISAISGDG
TQALVQAAHRWLTEQRQLEAEDETAFEHEREMRRRMEDEAVARAEARMSRKRKPAEDDDDDFDEDDYDVEVEYAP
>Mature_395_residues
MQFVDEASIIVEAGKGGNGCLSFRREKYVPKGGPDGGDGGHGGSVYLIGDESLNTLIDFKYQRFYKAPNGQPGQGRQMSG
RNGEDLHVKVPVGTTVIDEDTLEVIADVTEAGQVVLVAQAGRRGLGNIHFKSSTNRAPRKTTPGTEGERRNLRFEMKVMA
DVGLLGVPNAGKSTLIRAVSAAKPKVANYPFTTLVPNLGVVKLGTHEHFVMADVPGLIEGASDGAGLGLRFLKHLTRTRL
LLHVVDVAPFDESDPVDSARAIAHELEQFSATLAERPRWLVLNKLDLLPEEERPSTVDDIVERLAWSGPVYKISAISGDG
TQALVQAAHRWLTEQRQLEAEDETAFEHEREMRRRMEDEAVARAEARMSRKRKPAEDDDDDFDEDDYDVEVEYAP

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=325, Percent_Identity=39.6923076923077, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI111955139, Length=365, Percent_Identity=32.0547945205479, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI111955063, Length=207, Percent_Identity=35.2657004830918, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI4758796, Length=118, Percent_Identity=35.5932203389831, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1789574, Length=342, Percent_Identity=57.3099415204678, Blast_Score=372, Evalue=1e-104,
Organism=Escherichia coli, GI1787454, Length=140, Percent_Identity=35, Blast_Score=72, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17508313, Length=327, Percent_Identity=39.1437308868502, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17552324, Length=312, Percent_Identity=31.0897435897436, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17555344, Length=118, Percent_Identity=34.7457627118644, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17509631, Length=128, Percent_Identity=33.59375, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321962, Length=162, Percent_Identity=38.2716049382716, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6319281, Length=126, Percent_Identity=33.3333333333333, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20129375, Length=329, Percent_Identity=39.5136778115502, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24585318, Length=372, Percent_Identity=33.0645161290323, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI17981711, Length=118, Percent_Identity=34.7457627118644, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_CHRSD (Q1R0C0)

Other databases:

- EMBL:   CP000285
- RefSeq:   YP_572537.1
- ProteinModelPortal:   Q1R0C0
- STRING:   Q1R0C0
- GeneID:   4026500
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_0476
- NMPDR:   fig|290398.4.peg.14
- eggNOG:   COG0536
- HOGENOM:   HBG716038
- OMA:   YIQADEN
- ProtClustDB:   PRK12298
- BioCyc:   CSAL290398:CSAL_0476-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 43395; Mature: 43395

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFVDEASIIVEAGKGGNGCLSFRREKYVPKGGPDGGDGGHGGSVYLIGDESLNTLIDFK
CCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHH
YQRFYKAPNGQPGQGRQMSGRNGEDLHVKVPVGTTVIDEDTLEVIADVTEAGQVVLVAQA
HHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEECHHHHHHHHHHHCCCCEEEEEEC
GRRGLGNIHFKSSTNRAPRKTTPGTEGERRNLRFEMKVMADVGLLGVPNAGKSTLIRAVS
CCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCEEECCCCCHHHHHHHHH
AAKPKVANYPFTTLVPNLGVVKLGTHEHFVMADVPGLIEGASDGAGLGLRFLKHLTRTRL
HCCCCCCCCCHHHHCCCCCEEEECCCCEEEEECCCHHHCCCCCCCCHHHHHHHHHHHHHH
LLHVVDVAPFDESDPVDSARAIAHELEQFSATLAERPRWLVLNKLDLLPEEERPSTVDDI
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHCCCCCCCCCHHHHH
VERLAWSGPVYKISAISGDGTQALVQAAHRWLTEQRQLEAEDETAFEHEREMRRRMEDEA
HHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
VARAEARMSRKRKPAEDDDDDFDEDDYDVEVEYAP
HHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECC
>Mature Secondary Structure
MQFVDEASIIVEAGKGGNGCLSFRREKYVPKGGPDGGDGGHGGSVYLIGDESLNTLIDFK
CCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHH
YQRFYKAPNGQPGQGRQMSGRNGEDLHVKVPVGTTVIDEDTLEVIADVTEAGQVVLVAQA
HHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEECHHHHHHHHHHHCCCCEEEEEEC
GRRGLGNIHFKSSTNRAPRKTTPGTEGERRNLRFEMKVMADVGLLGVPNAGKSTLIRAVS
CCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCEEECCCCCHHHHHHHHH
AAKPKVANYPFTTLVPNLGVVKLGTHEHFVMADVPGLIEGASDGAGLGLRFLKHLTRTRL
HCCCCCCCCCHHHHCCCCCEEEECCCCEEEEECCCHHHCCCCCCCCHHHHHHHHHHHHHH
LLHVVDVAPFDESDPVDSARAIAHELEQFSATLAERPRWLVLNKLDLLPEEERPSTVDDI
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHCCCCCCCCCHHHHH
VERLAWSGPVYKISAISGDGTQALVQAAHRWLTEQRQLEAEDETAFEHEREMRRRMEDEA
HHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
VARAEARMSRKRKPAEDDDDDFDEDDYDVEVEYAP
HHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA