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The map label for this gene is lsrR [H]

Identifier: 92112491

GI number: 92112491

Start: 400851

End: 401831

Strand: Direct

Name: lsrR [H]

Synonym: Csal_0358

Alternate gene names: 92112491

Gene position: 400851-401831 (Clockwise)

Preceding gene: 92112490

Following gene: 92112492

Centisome position: 10.84

GC content: 64.93

Gene sequence:

>981_bases
ATGAGTGAGCGTGCCGAGAGCGCCGATGTTGCGCTGATGACCGAAATTGCCACGTTGTATTACGTGGAGGGGGAGACCCA
GGAGGCCATCGCCAACCGGCTGGGCATTTCGCGCGTCAAGGCCGGGCGCCTGTTGAAGCGCGCGCATGCCGAGGGCATCG
TCGACGTACGCGTGCGCCAGCACCCGGCGGTGAGCGCCGAGCTCGAACAGGCGCTGATCCGGCGTTTCGGCATCAAGCGG
GCGTTGATCGCGCTCGATCACGCCGATCCGGATACCCAGCGTTCCGGTGTGGCCAGCCTGGTGGCGGATCATCTCTCTCG
TTCGCTGCACGACGGTTCGATCGTGGCGGTGGGCATGGGACGCAATGTAGGGGCCGTGGCCGATAACGTGTTCGAACAGG
GGGAGCGCAAATGCTCGTTCGTTTGCGCGATCGGCGGATCCCTGCGCGCCGGGGAGTACATGAATCCCGATCATATCTGT
CGCCGACTGGCGATGAAGTACGGCGGGGAAAGCGAGACGCTGTATGCGCCGGCGCTCGTGCAGAATCCGGCGCTGCGCGA
CTCGATGTATGAAAACCCCACCGTGCGCCAGACCCTGGACCGCGCGCGGCGGGCGGATGTCGCCTTGATCGGCGTGGGCG
ACCTCAGCGAGGACAGCAACATGGTGCGCATGGGCTGGTTCACGCCGCAGGAAATCGCCGAGGCACGCCTGTCGGGCACG
GTGGGCGACATGATGGGGTATGACTTCATCGACATGCATGGCCGCCCCTCGGAAACGCCGATGCAGGGGCGGGTCATCGG
CCTGACCATAACCGATCTGGCGCGAATTCCCGATGTCGTGGCCATCGCCAGCGAGAATACCAAGGCGGCGGGGATTCTCG
GCGCCCTGCGTACGGGCGTCATCGATACCTTGGCCACTAGCGTCACCAACGCTCACACCATCCTGCGCCTGGACGAGGCG
ACGACTTCTCAGGCGTCTTGA

Upstream 100 bases:

>100_bases
AAACCTTTCGTGACCCGCCGCGCGTCTGATCGCCGAGAGCACGCTTGTTCGCTGTGGTATCTTGTGCGCATCGTTCGAGC
GGATCGCGTGAGGAGCAGTC

Downstream 100 bases:

>100_bases
GGCATTCGTCGCATGACAGGGAGAGGGTTTGATCACATGAACATGAATTTGTTCATGTGATCGTCTTTGCTATGGGTAAT
CATGGCGCCAGATCATGGAT

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MSERAESADVALMTEIATLYYVEGETQEAIANRLGISRVKAGRLLKRAHAEGIVDVRVRQHPAVSAELEQALIRRFGIKR
ALIALDHADPDTQRSGVASLVADHLSRSLHDGSIVAVGMGRNVGAVADNVFEQGERKCSFVCAIGGSLRAGEYMNPDHIC
RRLAMKYGGESETLYAPALVQNPALRDSMYENPTVRQTLDRARRADVALIGVGDLSEDSNMVRMGWFTPQEIAEARLSGT
VGDMMGYDFIDMHGRPSETPMQGRVIGLTITDLARIPDVVAIASENTKAAGILGALRTGVIDTLATSVTNAHTILRLDEA
TTSQAS

Sequences:

>Translated_326_residues
MSERAESADVALMTEIATLYYVEGETQEAIANRLGISRVKAGRLLKRAHAEGIVDVRVRQHPAVSAELEQALIRRFGIKR
ALIALDHADPDTQRSGVASLVADHLSRSLHDGSIVAVGMGRNVGAVADNVFEQGERKCSFVCAIGGSLRAGEYMNPDHIC
RRLAMKYGGESETLYAPALVQNPALRDSMYENPTVRQTLDRARRADVALIGVGDLSEDSNMVRMGWFTPQEIAEARLSGT
VGDMMGYDFIDMHGRPSETPMQGRVIGLTITDLARIPDVVAIASENTKAAGILGALRTGVIDTLATSVTNAHTILRLDEA
TTSQAS
>Mature_325_residues
SERAESADVALMTEIATLYYVEGETQEAIANRLGISRVKAGRLLKRAHAEGIVDVRVRQHPAVSAELEQALIRRFGIKRA
LIALDHADPDTQRSGVASLVADHLSRSLHDGSIVAVGMGRNVGAVADNVFEQGERKCSFVCAIGGSLRAGEYMNPDHICR
RLAMKYGGESETLYAPALVQNPALRDSMYENPTVRQTLDRARRADVALIGVGDLSEDSNMVRMGWFTPQEIAEARLSGTV
GDMMGYDFIDMHGRPSETPMQGRVIGLTITDLARIPDVVAIASENTKAAGILGALRTGVIDTLATSVTNAHTILRLDEAT
TSQAS

Specific function: In the absence of autoinducer 2 (AI-2), represses transcription of the lsrACDBFGE operon and its own transcription. In the presence of AI-2, lsrR is inactivated by binding phospho- AI-2, leading to the transcription of the lsr genes [H]

COG id: COG2390

COG function: function code K; Transcriptional regulator, contains sigma factor-related N-terminal domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sorC transcriptional regulatory family [H]

Homologues:

Organism=Escherichia coli, GI1787791, Length=310, Percent_Identity=28.3870967741935, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI87082414, Length=303, Percent_Identity=23.4323432343234, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04198 Sugar-bind [H]

EC number: NA

Molecular weight: Translated: 35141; Mature: 35010

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERAESADVALMTEIATLYYVEGETQEAIANRLGISRVKAGRLLKRAHAEGIVDVRVRQ
CCCCCCCCCHHHHHHHEEEEEECCCHHHHHHHHHCHHHHHHHHHHHHHHHCCEEEEEECC
HPAVSAELEQALIRRFGIKRALIALDHADPDTQRSGVASLVADHLSRSLHDGSIVAVGMG
CCCHHHHHHHHHHHHHCHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECC
RNVGAVADNVFEQGERKCSFVCAIGGSLRAGEYMNPDHICRRLAMKYGGESETLYAPALV
CCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCHHH
QNPALRDSMYENPTVRQTLDRARRADVALIGVGDLSEDSNMVRMGWFTPQEIAEARLSGT
CCCCHHHHHCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCEEEEECCCHHHHHHHHHCCC
VGDMMGYDFIDMHGRPSETPMQGRVIGLTITDLARIPDVVAIASENTKAAGILGALRTGV
HHHHHCCCEEECCCCCCCCCCCCEEEEEEHHHHHHCCCEEEEECCCCCHHHHHHHHHHHH
IDTLATSVTNAHTILRLDEATTSQAS
HHHHHHHHCCCEEEEEECCCCCCCCC
>Mature Secondary Structure 
SERAESADVALMTEIATLYYVEGETQEAIANRLGISRVKAGRLLKRAHAEGIVDVRVRQ
CCCCCCCCHHHHHHHEEEEEECCCHHHHHHHHHCHHHHHHHHHHHHHHHCCEEEEEECC
HPAVSAELEQALIRRFGIKRALIALDHADPDTQRSGVASLVADHLSRSLHDGSIVAVGMG
CCCHHHHHHHHHHHHHCHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECC
RNVGAVADNVFEQGERKCSFVCAIGGSLRAGEYMNPDHICRRLAMKYGGESETLYAPALV
CCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCHHH
QNPALRDSMYENPTVRQTLDRARRADVALIGVGDLSEDSNMVRMGWFTPQEIAEARLSGT
CCCCHHHHHCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCEEEEECCCHHHHHHHHHCCC
VGDMMGYDFIDMHGRPSETPMQGRVIGLTITDLARIPDVVAIASENTKAAGILGALRTGV
HHHHHCCCEEECCCCCCCCCCCCEEEEEEHHHHHHCCCEEEEECCCCCHHHHHHHHHHHH
IDTLATSVTNAHTILRLDEATTSQAS
HHHHHHHHCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA