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The map label for this gene is siaT [H]

Identifier: 92112439

GI number: 92112439

Start: 343861

End: 345147

Strand: Direct

Name: siaT [H]

Synonym: Csal_0305

Alternate gene names: 92112439

Gene position: 343861-345147 (Clockwise)

Preceding gene: 92112438

Following gene: 92112440

Centisome position: 9.3

GC content: 62.47

Gene sequence:

>1287_bases
ATGGGGAGTGAAATGATTGGCGGTATCGGCCTGGCCTTGCTGCTGGTGCTGATGATGCTGCGCGTGCCGGTGGCGCTGAC
GATGCTCATCGTCGGGGTGGTGGGTTTCTCGCAGGTCATCAACATGGGCGCGGCCCTGTCGATGGTCAAATCCGTGCCCG
TGGAGGTGCTGTCGAACTACAGCTTCAGCGCGGTGCCCATGTTCATCCTCATGGGCGTGCTGGCCGCGCATTCGGGCATG
GCCGGGAAGCTGTTCAATTCCACCCGCGTCATCTGTGGCGGCTGGAAAGGCGGCCTGGCCATCGCGGCGATCGGTTCTTG
CGGCATCTTCTCGGCGATTTCCGGCTCCTCCCTGGCTACCGCGAGCACCATGACCCGCGTCGCCCTCCCGGAGATGGAGC
GTTACGGCTACAACCGTGGCCTGGCGACAGGGGCGCTGGCCGCCGGCGGCACGCTGGGCATCATGATTCCGCCGAGCATC
GCGCTTTTGATCTACGCCATCCTGACCGAGCAATCGGTGGGCGACATGTTCATGGCGGGGCTCATTCCCGGCCTGATGGG
GCTGTTGTTCTATTCGCTGGCGATCACGGTGGTGATGCGGCTCAAGCCGTCGTTGGCCGTGGCCGGCGAATCCACCACCT
GGAGCGAGAAGGTCAAGTCCCTGGTGGGCCTGGTGCCGTTCTTCGGTGTCTTCCTGCTGCTCATCCTGGGGATCTATTTC
GGTGCCTTCACGCCCACCGAGGGGGCGAGCGTCGGGGCCTTCGCCACCTTGCTGTATGCCGTGGCCAAAGGCATGCGCGC
CCGGGGCTTGTGGCAGTCGGTACAGGAAACGCTGGCGCTTTCCTCGGTCGTCTTCTTCATGCTGGTCGGGGCCGAGACGC
TGGGCTATTTCATCTCGGTATCGCGGATCTCCTTCACCATCAGCGATTTCCTGTTCAGCCTGGATCTCACTCCGATCGTC
GTGCTGCTGTGCATCCTGCTGCTGTACTTCGTGCTCGGCATGTTCATGGACTCCATCGCCATGCTGGTGATCACCGTGCC
GGTGGTGTTTCCGATCATTCAGAGCGTGGGCATCGACCCGGTCTGGTTCGGCATCGTGACGGTACTGACCGTCGAGCTGG
GCTTGATCACGCCGCCAGTGGGAATGAACGTCTTCGTCATCAAGGCCATGGCTCCCCACGTGGGGTTGGGCGAGATCTTC
AAGGGGGTCGCGCCCTTCATCGCCGCCGATTTCGTGCGCCTGGCGCTATTGATCGCATTTCCCGTACTCAGTCTGTTTCT
CATCTGA

Upstream 100 bases:

>100_bases
ATCTATCTTTTTGCCGCCTTCCTGAGTGCGTTGCTCAGCTTGCGTAGCCTGCTGCATGTGCTGCTGAGCGGCGTCTTCGG
CCAAGAGGAGGAAACCGCTC

Downstream 100 bases:

>100_bases
TTCCAGGAGTGGAACGCGCGAGTGGTATGAAAGGACACAAACGCTAGCCATCAACACATCATGAGGTACCAACAATGAAA
ACAATCTATTACGCCGCTGG

Product: TRAP dicarboxylate transporter subunit DctM

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MGSEMIGGIGLALLLVLMMLRVPVALTMLIVGVVGFSQVINMGAALSMVKSVPVEVLSNYSFSAVPMFILMGVLAAHSGM
AGKLFNSTRVICGGWKGGLAIAAIGSCGIFSAISGSSLATASTMTRVALPEMERYGYNRGLATGALAAGGTLGIMIPPSI
ALLIYAILTEQSVGDMFMAGLIPGLMGLLFYSLAITVVMRLKPSLAVAGESTTWSEKVKSLVGLVPFFGVFLLLILGIYF
GAFTPTEGASVGAFATLLYAVAKGMRARGLWQSVQETLALSSVVFFMLVGAETLGYFISVSRISFTISDFLFSLDLTPIV
VLLCILLLYFVLGMFMDSIAMLVITVPVVFPIIQSVGIDPVWFGIVTVLTVELGLITPPVGMNVFVIKAMAPHVGLGEIF
KGVAPFIAADFVRLALLIAFPVLSLFLI

Sequences:

>Translated_428_residues
MGSEMIGGIGLALLLVLMMLRVPVALTMLIVGVVGFSQVINMGAALSMVKSVPVEVLSNYSFSAVPMFILMGVLAAHSGM
AGKLFNSTRVICGGWKGGLAIAAIGSCGIFSAISGSSLATASTMTRVALPEMERYGYNRGLATGALAAGGTLGIMIPPSI
ALLIYAILTEQSVGDMFMAGLIPGLMGLLFYSLAITVVMRLKPSLAVAGESTTWSEKVKSLVGLVPFFGVFLLLILGIYF
GAFTPTEGASVGAFATLLYAVAKGMRARGLWQSVQETLALSSVVFFMLVGAETLGYFISVSRISFTISDFLFSLDLTPIV
VLLCILLLYFVLGMFMDSIAMLVITVPVVFPIIQSVGIDPVWFGIVTVLTVELGLITPPVGMNVFVIKAMAPHVGLGEIF
KGVAPFIAADFVRLALLIAFPVLSLFLI
>Mature_427_residues
GSEMIGGIGLALLLVLMMLRVPVALTMLIVGVVGFSQVINMGAALSMVKSVPVEVLSNYSFSAVPMFILMGVLAAHSGMA
GKLFNSTRVICGGWKGGLAIAAIGSCGIFSAISGSSLATASTMTRVALPEMERYGYNRGLATGALAAGGTLGIMIPPSIA
LLIYAILTEQSVGDMFMAGLIPGLMGLLFYSLAITVVMRLKPSLAVAGESTTWSEKVKSLVGLVPFFGVFLLLILGIYFG
AFTPTEGASVGAFATLLYAVAKGMRARGLWQSVQETLALSSVVFFMLVGAETLGYFISVSRISFTISDFLFSLDLTPIVV
LLCILLLYFVLGMFMDSIAMLVITVPVVFPIIQSVGIDPVWFGIVTVLTVELGLITPPVGMNVFVIKAMAPHVGLGEIFK
GVAPFIAADFVRLALLIAFPVLSLFLI

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=354, Percent_Identity=28.8135593220339, Blast_Score=127, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 44986; Mature: 44855

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSEMIGGIGLALLLVLMMLRVPVALTMLIVGVVGFSQVINMGAALSMVKSVPVEVLSNY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SFSAVPMFILMGVLAAHSGMAGKLFNSTRVICGGWKGGLAIAAIGSCGIFSAISGSSLAT
CCHHHHHHHHHHHHHHCCCCCHHHHCCCEEEECCCCCCCHHHHHCCCHHHHHCCCCCHHH
ASTMTRVALPEMERYGYNRGLATGALAAGGTLGIMIPPSIALLIYAILTEQSVGDMFMAG
HHHHHHHHHHHHHHCCCCCCCCHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
LIPGLMGLLFYSLAITVVMRLKPSLAVAGESTTWSEKVKSLVGLVPFFGVFLLLILGIYF
HHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAFTPTEGASVGAFATLLYAVAKGMRARGLWQSVQETLALSSVVFFMLVGAETLGYFISV
CCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRISFTISDFLFSLDLTPIVVLLCILLLYFVLGMFMDSIAMLVITVPVVFPIIQSVGIDP
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
VWFGIVTVLTVELGLITPPVGMNVFVIKAMAPHVGLGEIFKGVAPFIAADFVRLALLIAF
HHHHHHHHHHHHHHHCCCCCCCCEEEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
PVLSLFLI
HHHHHHHC
>Mature Secondary Structure 
GSEMIGGIGLALLLVLMMLRVPVALTMLIVGVVGFSQVINMGAALSMVKSVPVEVLSNY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SFSAVPMFILMGVLAAHSGMAGKLFNSTRVICGGWKGGLAIAAIGSCGIFSAISGSSLAT
CCHHHHHHHHHHHHHHCCCCCHHHHCCCEEEECCCCCCCHHHHHCCCHHHHHCCCCCHHH
ASTMTRVALPEMERYGYNRGLATGALAAGGTLGIMIPPSIALLIYAILTEQSVGDMFMAG
HHHHHHHHHHHHHHCCCCCCCCHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
LIPGLMGLLFYSLAITVVMRLKPSLAVAGESTTWSEKVKSLVGLVPFFGVFLLLILGIYF
HHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAFTPTEGASVGAFATLLYAVAKGMRARGLWQSVQETLALSSVVFFMLVGAETLGYFISV
CCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRISFTISDFLFSLDLTPIVVLLCILLLYFVLGMFMDSIAMLVITVPVVFPIIQSVGIDP
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
VWFGIVTVLTVELGLITPPVGMNVFVIKAMAPHVGLGEIFKGVAPFIAADFVRLALLIAF
HHHHHHHHHHHHHHHCCCCCCCCEEEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
PVLSLFLI
HHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]