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The map label for this gene is ttcA [H]

Identifier: 91785571

GI number: 91785571

Start: 4627865

End: 4628875

Strand: Reverse

Name: ttcA [H]

Synonym: Bxe_A0206

Alternate gene names: 91785571

Gene position: 4628875-4627865 (Counterclockwise)

Preceding gene: 91785572

Following gene: 91785570

Centisome position: 94.55

GC content: 60.83

Gene sequence:

>1011_bases
ATGAATGCTCCGGAAATCCTGAACGGCGCCACTGCCGCCGCGCCCGCCGGTACAGGCGAGGCGACGCCAGTCCACGCGCG
CGCCAGATCGCCGCTCACGCGCCGCGAACAGAAGGAAGCGTACGAGAACAACAAGCTGTTCAAGCGGCTCGCGCGCCAGG
TCGGCGAGGCGATCGTCGACTTCAACATGATCGAGGACGGCGACAAGGTGATGGTCTGCCTGTCCGGCGGCAAGGACAGC
TATGCGATGCTCGAAATCCTGATGCGGCTGCGCGAGCGCGCGCCGATCAACTTCGACATCGTCGCCGTCAATCTCGACCA
GAAGCAGCCGGGCTTTCCCGAGCACGTGCTGCCCGAGTACCTGAAGCAGCTCGACATTCCGTTTCACATCGAGAATCAGG
ATACGTACAGCATCGTCAAGCGGCTGGTGCCGGAAGGCAAGACCACCTGCTCGCTGTGCTCGCGGCTGCGGCGCGGCATT
CTGTACCGCGTGGCGGGTGAACTGGGCGCGACCAAGATCGCGCTCGGCCATCATCGCGACGACATTCTGCAAACGCTGCT
GCTGAACATGTTCTACGGCGGCAAGCTGAAGGGCATGCCGCCCAAGCTGCAATCCGACGACGGCAAGAATATCGTGATCC
GCCCGCTTGCCTACGTGAAGGAAACCGATCTGGAGAAGTACGCCGAGCTGCGCGAATTCCCGATCATTCCGTGCAACCTG
TGCGGCAGCCAGCCGAATCTCAAGCGCGCGGAAATGAAGGCACTGGTCCGCGACTGGGAGAAACGCTTCCCGGGCCGCAT
TGAAAATATGTTCAATGCGTTGGCGAATGTCGTGCCCTCGCATTTGATGGATCACAAGCTGTTTCCATTCGCTGGCCTGC
GGGCGACCGGCGAGGCCGATCCGCAAGGCGATATTGCATTCGACGAAGAGCCGTGTTCGACCGACAGCGGTAATAGCACG
ACGCTTGACGGAGCGAAATCGATTGCAATCGTCCAGTTTGACGATCTTTGA

Upstream 100 bases:

>100_bases
GCAAGTGCGGGCGGCGCGTGTGTCGACGGAAAAGCCGGACGTTTATCCCGACTGCGACGCGGTGGGCGTCGAGGTCTTCC
GTATCAAGGAGGATTGAGCC

Downstream 100 bases:

>100_bases
CCAAAACGCCCGTGGCACGGGCGTCTCCGCGCATTCCAGTTTGCAACGAGGCCGCTCAAGCGGCCTTTTCTGCTAGAGGG
TGCGTGTTAGAATCGTCGGC

Product: C32 tRNA thiolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MNAPEILNGATAAAPAGTGEATPVHARARSPLTRREQKEAYENNKLFKRLARQVGEAIVDFNMIEDGDKVMVCLSGGKDS
YAMLEILMRLRERAPINFDIVAVNLDQKQPGFPEHVLPEYLKQLDIPFHIENQDTYSIVKRLVPEGKTTCSLCSRLRRGI
LYRVAGELGATKIALGHHRDDILQTLLLNMFYGGKLKGMPPKLQSDDGKNIVIRPLAYVKETDLEKYAELREFPIIPCNL
CGSQPNLKRAEMKALVRDWEKRFPGRIENMFNALANVVPSHLMDHKLFPFAGLRATGEADPQGDIAFDEEPCSTDSGNST
TLDGAKSIAIVQFDDL

Sequences:

>Translated_336_residues
MNAPEILNGATAAAPAGTGEATPVHARARSPLTRREQKEAYENNKLFKRLARQVGEAIVDFNMIEDGDKVMVCLSGGKDS
YAMLEILMRLRERAPINFDIVAVNLDQKQPGFPEHVLPEYLKQLDIPFHIENQDTYSIVKRLVPEGKTTCSLCSRLRRGI
LYRVAGELGATKIALGHHRDDILQTLLLNMFYGGKLKGMPPKLQSDDGKNIVIRPLAYVKETDLEKYAELREFPIIPCNL
CGSQPNLKRAEMKALVRDWEKRFPGRIENMFNALANVVPSHLMDHKLFPFAGLRATGEADPQGDIAFDEEPCSTDSGNST
TLDGAKSIAIVQFDDL
>Mature_336_residues
MNAPEILNGATAAAPAGTGEATPVHARARSPLTRREQKEAYENNKLFKRLARQVGEAIVDFNMIEDGDKVMVCLSGGKDS
YAMLEILMRLRERAPINFDIVAVNLDQKQPGFPEHVLPEYLKQLDIPFHIENQDTYSIVKRLVPEGKTTCSLCSRLRRGI
LYRVAGELGATKIALGHHRDDILQTLLLNMFYGGKLKGMPPKLQSDDGKNIVIRPLAYVKETDLEKYAELREFPIIPCNL
CGSQPNLKRAEMKALVRDWEKRFPGRIENMFNALANVVPSHLMDHKLFPFAGLRATGEADPQGDIAFDEEPCSTDSGNST
TLDGAKSIAIVQFDDL

Specific function: Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) [H]

COG id: COG0037

COG function: function code D; Predicted ATPase of the PP-loop superfamily implicated in cell cycle control

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TtcA family [H]

Homologues:

Organism=Escherichia coli, GI1787606, Length=274, Percent_Identity=70.4379562043796, Blast_Score=414, Evalue=1e-117,
Organism=Caenorhabditis elegans, GI193211090, Length=242, Percent_Identity=33.0578512396694, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17540090, Length=231, Percent_Identity=29.004329004329, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24651972, Length=255, Percent_Identity=28.2352941176471, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012089
- InterPro:   IPR014729
- InterPro:   IPR011063 [H]

Pfam domain/function: PF01171 ATP_bind_3 [H]

EC number: NA

Molecular weight: Translated: 37418; Mature: 37418

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPEILNGATAAAPAGTGEATPVHARARSPLTRREQKEAYENNKLFKRLARQVGEAIVD
CCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FNMIEDGDKVMVCLSGGKDSYAMLEILMRLRERAPINFDIVAVNLDQKQPGFPEHVLPEY
HHEECCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCHHHHHHH
LKQLDIPFHIENQDTYSIVKRLVPEGKTTCSLCSRLRRGILYRVAGELGATKIALGHHRD
HHHCCCCEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHH
DILQTLLLNMFYGGKLKGMPPKLQSDDGKNIVIRPLAYVKETDLEKYAELREFPIIPCNL
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCHHC
CGSQPNLKRAEMKALVRDWEKRFPGRIENMFNALANVVPSHLMDHKLFPFAGLRATGEAD
CCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
PQGDIAFDEEPCSTDSGNSTTLDGAKSIAIVQFDDL
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCC
>Mature Secondary Structure
MNAPEILNGATAAAPAGTGEATPVHARARSPLTRREQKEAYENNKLFKRLARQVGEAIVD
CCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FNMIEDGDKVMVCLSGGKDSYAMLEILMRLRERAPINFDIVAVNLDQKQPGFPEHVLPEY
HHEECCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCHHHHHHH
LKQLDIPFHIENQDTYSIVKRLVPEGKTTCSLCSRLRRGILYRVAGELGATKIALGHHRD
HHHCCCCEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHH
DILQTLLLNMFYGGKLKGMPPKLQSDDGKNIVIRPLAYVKETDLEKYAELREFPIIPCNL
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCHHC
CGSQPNLKRAEMKALVRDWEKRFPGRIENMFNALANVVPSHLMDHKLFPFAGLRATGEAD
CCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
PQGDIAFDEEPCSTDSGNSTTLDGAKSIAIVQFDDL
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA