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The map label for this gene is glmU [H]

Identifier: 91785570

GI number: 91785570

Start: 4626378

End: 4627781

Strand: Reverse

Name: glmU [H]

Synonym: Bxe_A0207

Alternate gene names: 91785570

Gene position: 4627781-4626378 (Counterclockwise)

Preceding gene: 91785571

Following gene: 91785569

Centisome position: 94.52

GC content: 65.03

Gene sequence:

>1404_bases
GTGTTAGAATCGTCGGCTCCAAACTCGTCTATTTGCGGTGCCATGAACATTGTGATTTTGGCGGCAGGCACCGGCAAGCG
CATGCGGTCCGCGCTTCCCAAAGTGCTGCATCCCCTGGCCGGTCGGCCGCTCCTCGCTCACGTCATCGACACGGCTCGCA
CGCTCAAGCCCACGCATCTCGTGGTAGTGATCGGCCACGGCGCCGAAGCCGTGCGCAAAGCCGTGGCGGCGCCGGACGTG
CAGTTCGCCGTGCAGGAGCAGCAGCTCGGCACGGGCCACGCGGTGCAGCAGGCGTTGCCGCTGCTCGATCCGTCCGCGCC
CACGCTGGTGCTTTACGGCGACGTGCCGCTTACGCGTGCCGGCACGCTGCAGGCGTTGACCGATCGCGCGGGGCAGGGCG
GCTACGGCGTGCTCACCGTCACGCTGGCTGATCCGAGCGGTTACGGGCGCATCGTGCGCGATGCGCATGGCAAGGTGGCG
CGCATCGTCGAGCAGAAAGACGCTACGCCCGAGCAGCTCGCGATCGCCGAGATCAACACCGGCATCATCGTCGCGCCGAC
CGAACGTCTGGGCGACTGGCTCGCCGCGCTGAAGAACGACAATGCGCAAGGCGAGTTCTATCTGACCGACGCGGTGGAAA
TGGCGATCGAGGCTGGCCTCGAAGTCGTCACCACGCAACCGGACCACGAATGGGAAACGCTCGGCGTGAACAGCAAGCAG
CAGCTTGCCGAACTGGAGCGGATTCATCAGCGCAACGTGGCTGACGCGTTGCTGGTCGCGGGCGTGACACTCGCCGATCC
GGCGCGTCTGGACGTGCGCGGCACGCTCGAATGCGGCCGCGATGTCTCGATCGACGTGAACTGCGTATTCGAAGGCCGTG
TCACGCTGGCCGACAACGTCACCGTCGGGCCGAACTGCGTGATCCGCAATGCGAACATCGGCGCCGGTACGCGCGTCGAC
GCGTTCACCCATATCGAAGGCGCCGAGGTCGGCGCGAATGTCGTGCTCGGACCGTATGCGCGCTTGCGCCCCGGTGCTTC
GCTGCACGACGAGTCGCATGTCGGCAACTTCGTCGAGGTGAAGAACGCGGTGCTCGGTCACGGTTCGAAGGCGAATCACC
TCACGTATATCGGCGACGCGGATATCGGCGCGCGGGTGAACATCGGCGCGGGCACCATCACCTGCAATTACGATGGCGCG
AACAAATTCCGCACGATTATCGAAGACGACGTGTTCGTCGGTTCGGACACGCAACTGGTCGCGCCGGTGCGTGTGAAGCG
CGGCGCCACGATCGCGGCGGGCACCACGGTCTGGAAGGACGTCGAAGCTGATGCACTGGTCCTGAACGACAAGACGCAAA
CTAGCAGAACGGGCTACGTGCGCCCGACCAAAAAGAAGAGCTGA

Upstream 100 bases:

>100_bases
AGTTTGACGATCTTTGACCAAAACGCCCGTGGCACGGGCGTCTCCGCGCATTCCAGTTTGCAACGAGGCCGCTCAAGCGG
CCTTTTCTGCTAGAGGGTGC

Downstream 100 bases:

>100_bases
TGGGTACGACGCGCGCCCGAGGCGCGCTCCTTGAAACCCGGCACTAGCACTGAAAAAGGAATGATCCATGTGTGGCATTG
TCGGCGCGGTAGCGCAACGT

Product: UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MLESSAPNSSICGAMNIVILAAGTGKRMRSALPKVLHPLAGRPLLAHVIDTARTLKPTHLVVVIGHGAEAVRKAVAAPDV
QFAVQEQQLGTGHAVQQALPLLDPSAPTLVLYGDVPLTRAGTLQALTDRAGQGGYGVLTVTLADPSGYGRIVRDAHGKVA
RIVEQKDATPEQLAIAEINTGIIVAPTERLGDWLAALKNDNAQGEFYLTDAVEMAIEAGLEVVTTQPDHEWETLGVNSKQ
QLAELERIHQRNVADALLVAGVTLADPARLDVRGTLECGRDVSIDVNCVFEGRVTLADNVTVGPNCVIRNANIGAGTRVD
AFTHIEGAEVGANVVLGPYARLRPGASLHDESHVGNFVEVKNAVLGHGSKANHLTYIGDADIGARVNIGAGTITCNYDGA
NKFRTIIEDDVFVGSDTQLVAPVRVKRGATIAAGTTVWKDVEADALVLNDKTQTSRTGYVRPTKKKS

Sequences:

>Translated_467_residues
MLESSAPNSSICGAMNIVILAAGTGKRMRSALPKVLHPLAGRPLLAHVIDTARTLKPTHLVVVIGHGAEAVRKAVAAPDV
QFAVQEQQLGTGHAVQQALPLLDPSAPTLVLYGDVPLTRAGTLQALTDRAGQGGYGVLTVTLADPSGYGRIVRDAHGKVA
RIVEQKDATPEQLAIAEINTGIIVAPTERLGDWLAALKNDNAQGEFYLTDAVEMAIEAGLEVVTTQPDHEWETLGVNSKQ
QLAELERIHQRNVADALLVAGVTLADPARLDVRGTLECGRDVSIDVNCVFEGRVTLADNVTVGPNCVIRNANIGAGTRVD
AFTHIEGAEVGANVVLGPYARLRPGASLHDESHVGNFVEVKNAVLGHGSKANHLTYIGDADIGARVNIGAGTITCNYDGA
NKFRTIIEDDVFVGSDTQLVAPVRVKRGATIAAGTTVWKDVEADALVLNDKTQTSRTGYVRPTKKKS
>Mature_467_residues
MLESSAPNSSICGAMNIVILAAGTGKRMRSALPKVLHPLAGRPLLAHVIDTARTLKPTHLVVVIGHGAEAVRKAVAAPDV
QFAVQEQQLGTGHAVQQALPLLDPSAPTLVLYGDVPLTRAGTLQALTDRAGQGGYGVLTVTLADPSGYGRIVRDAHGKVA
RIVEQKDATPEQLAIAEINTGIIVAPTERLGDWLAALKNDNAQGEFYLTDAVEMAIEAGLEVVTTQPDHEWETLGVNSKQ
QLAELERIHQRNVADALLVAGVTLADPARLDVRGTLECGRDVSIDVNCVFEGRVTLADNVTVGPNCVIRNANIGAGTRVD
AFTHIEGAEVGANVVLGPYARLRPGASLHDESHVGNFVEVKNAVLGHGSKANHLTYIGDADIGARVNIGAGTITCNYDGA
NKFRTIIEDDVFVGSDTQLVAPVRVKRGATIAAGTTVWKDVEADALVLNDKTQTSRTGYVRPTKKKS

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG1207

COG function: function code M; N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1790168, Length=453, Percent_Identity=56.0706401766004, Blast_Score=496, Evalue=1e-141,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 49286; Mature: 49286

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLESSAPNSSICGAMNIVILAAGTGKRMRSALPKVLHPLAGRPLLAHVIDTARTLKPTHL
CCCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEE
VVVIGHGAEAVRKAVAAPDVQFAVQEQQLGTGHAVQQALPLLDPSAPTLVLYGDVPLTRA
EEEEECCHHHHHHHHCCCCCEEEEEHHHCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCC
GTLQALTDRAGQGGYGVLTVTLADPSGYGRIVRDAHGKVARIVEQKDATPEQLAIAEINT
CHHHHHHHCCCCCCEEEEEEEEECCCCCCHHHHHCCCHHHHHHHHCCCCHHHEEEEEECC
GIIVAPTERLGDWLAALKNDNAQGEFYLTDAVEMAIEAGLEVVTTQPDHEWETLGVNSKQ
CEEEECHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHCCCEEEECCCCCCEEECCCCCHH
QLAELERIHQRNVADALLVAGVTLADPARLDVRGTLECGRDVSIDVNCVFEGRVTLADNV
HHHHHHHHHHCCHHHHHHHCCCEECCCCEEEEEEECCCCCCCEEEEEEEEECEEEEECCE
TVGPNCVIRNANIGAGTRVDAFTHIEGAEVGANVVLGPYARLRPGASLHDESHVGNFVEV
EECCCEEEEECCCCCCCCCCEEEECCCCCCCCCEEECCHHHCCCCCCCCCHHHCCCHHHH
KNAVLGHGSKANHLTYIGDADIGARVNIGAGTITCNYDGANKFRTIIEDDVFVGSDTQLV
HHHHHCCCCCCCEEEEEECCCCCCEEEECCEEEEEECCCCHHHHHHHCCCEEECCCCEEE
APVRVKRGATIAAGTTVWKDVEADALVLNDKTQTSRTGYVRPTKKKS
EEEEECCCCEEEECCCEEECCCCCEEEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLESSAPNSSICGAMNIVILAAGTGKRMRSALPKVLHPLAGRPLLAHVIDTARTLKPTHL
CCCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEE
VVVIGHGAEAVRKAVAAPDVQFAVQEQQLGTGHAVQQALPLLDPSAPTLVLYGDVPLTRA
EEEEECCHHHHHHHHCCCCCEEEEEHHHCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCC
GTLQALTDRAGQGGYGVLTVTLADPSGYGRIVRDAHGKVARIVEQKDATPEQLAIAEINT
CHHHHHHHCCCCCCEEEEEEEEECCCCCCHHHHHCCCHHHHHHHHCCCCHHHEEEEEECC
GIIVAPTERLGDWLAALKNDNAQGEFYLTDAVEMAIEAGLEVVTTQPDHEWETLGVNSKQ
CEEEECHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHCCCEEEECCCCCCEEECCCCCHH
QLAELERIHQRNVADALLVAGVTLADPARLDVRGTLECGRDVSIDVNCVFEGRVTLADNV
HHHHHHHHHHCCHHHHHHHCCCEECCCCEEEEEEECCCCCCCEEEEEEEEECEEEEECCE
TVGPNCVIRNANIGAGTRVDAFTHIEGAEVGANVVLGPYARLRPGASLHDESHVGNFVEV
EECCCEEEEECCCCCCCCCCEEEECCCCCCCCCEEECCHHHCCCCCCCCCHHHCCCHHHH
KNAVLGHGSKANHLTYIGDADIGARVNIGAGTITCNYDGANKFRTIIEDDVFVGSDTQLV
HHHHHCCCCCCCEEEEEECCCCCCEEEECCEEEEEECCCCHHHHHHHCCCEEECCCCEEE
APVRVKRGATIAAGTTVWKDVEADALVLNDKTQTSRTGYVRPTKKKS
EEEEECCCCEEEECCCEEECCCCCEEEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA