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The map label for this gene is maeB [H]

Identifier: 91785496

GI number: 91785496

Start: 4557640

End: 4559922

Strand: Reverse

Name: maeB [H]

Synonym: Bxe_A0283

Alternate gene names: 91785496

Gene position: 4559922-4557640 (Counterclockwise)

Preceding gene: 91785497

Following gene: 91785492

Centisome position: 93.14

GC content: 63.07

Gene sequence:

>2283_bases
ATGGACGAACAACTTAAGCAAAGCGCTCTCGCCTATCACCAGAACCCGAAACCCGGCAAGATTTCGGTCACCCCCACCAA
GCCGCTGTCGAACCAGCTCGATCTCTCGCTCGCATACTCGCCGGGCGTCGCCGCGGCGTGTATGGCGATCTACGACGAGC
CGCTCGACGCGCAGAAGTACACCTCGCGCGGCAACCTGGTCGGCGTGATCACCAATGGCACGGCCGTGCTCGGTCTCGGC
AACATCGGTCCGCTCGCCGCGAAACCCGTCATGGAAGGCAAGGGTTGCCTCTTCAAGAAATTCGCCGGCATCGACGTGTT
CGACATCGAACTCTCCGAGTCCGATCCGGACAAGCTCGTTGAGGCGATCGCCATGCTCGAGCCCACGCTCGGCGGCATCA
ACCTCGAAGACATCAAGGCGCCCGAGTGCTTCTACATCGAGAAGAAGCTGCGCGAGCGCATGAAGATTCCAGTCTTCCAC
GACGACCAGCACGGCACCGCGATCATCGCGTCGGCGGCGATCCTGAATGGTCTGAAAGTAGTCGGCAAGAAGCTCGGCGA
AGTGAAGCTCGTATGTTCCGGTGCGGGCGCGGCAGCGATCGCGTGTCTGGATCTGCTGGTGAACCTGGGCCTGTCGAAGA
AGAACATTCTGGTCACGGACTCCAAAGGCGTGATCTACGAAGGCCGCGGCAATCTCGATCCGTCGAAGGAACGTTACGCG
GCGAACACCGGCGCGCGCACGCTCGCTGACGCCATCCGCGGCGCCGACGTGTTCCTCGGCTGTTCGAGCGCGGGCGTGCT
GAAGCCGGAGATGGTCGCCGAAATGGGCACCCAGCCGCTGATTCTCGCGCTGGCGAATCCGGAGCCGGAAATCCGTCCGG
AAGACGCGAAGAAGGTTCGTCCGGACTGCATCATCGCGACCGGCCGTTCGGACTACCCGAACCAGGTCAACAACGTGCTG
TGCTTCCCGTTCATCTTCCGCGGCGCGCTGGACGTGGGCGCCACCACCATCACGGAAGAAATGAAGCTCGCGTGCGTGCG
CGCGATCGCCGAGCTGGCCGAAGAAACCGATCAGGGCGACGAAGTCGCGAAGGCCTACGAAGGCCACTCGCTGGAATTCG
GTCCCGAGTACCTGATTCCCAAGCCGTTCGATCCGCGCCTGATCATCAAGATCGCGCCGGCCGTCGCTCAGGCGGCAATG
GATTCGGGCGTTGCGACCCGTCCGATCAAGGACATGGACGCATACCGCGAAGAACTCGGCACCACGGTGTATCGCACCGG
CATGGTGATGCGTCCGGTGTTCGCCGCGGCGAAGTCGGAGCCGGCGCGCATCGTGTTCGCCGAAGGTGAAGACGAGCGCG
TGCTGCGTGCCGCGCAGTTCGTGCTGCTGGAAAAGATCGCCAGGCCGATTCTGGTTGGCCGTCCGTCGGTGATCGAGATG
CGTCTGAAAAAGATGGGCTCGAAGCTCAAGTGCGGCGACGACTTCGAGGTTGTCGATCCGGAGGACGATCCGCGCTATCA
GCAATCCTGGCAGGCCTATCACGAGCTCGGCGCGCGCGAAGGCGTGACGCCGGACGTGGCAAAGGCCGCCATGCGCAAGT
TCAATACGCTGATCGGCGCGATCCTCGTGCGCCTCGGCGAAGCCGACGGCATGATTTGCGGCATGATCGGCCAGTACCAC
ACGCACCTGAAGTTCATCGAACAGGTGCTGGGCAAAGCAGAGAACGTTCAGAACTTCGCGGCAATGAACCTGCTGATGCT
GCCGGGCCGCAATCTGTTCATCTGCGACACATACGTGAACGAGACGCCCACCGCCGAGCAACTGGCCGACATGACGATGC
TGGCTGCTGGCGAGATCGAGAAGTTCGGTATCACGCCGAAGGTCGCGTTGCTGTCGAACTCGAACTTCGGCAGCGCGCCT
TCTTCGTCGTCGCAGCGTATGGCCGCGGCTCGCAAGCTGATTGTCGAGCGCGCGCCAACGCTCGAGATCGACGGTGAGAT
GCACGGCGATGCGGCGTTGTCGGAAGCGGTGCGCAAGGCCGCGTTCCCCGGCACGACGCTGAGCGGCGAAGCCAACCTGC
TGATCATGCCGAACGTGGAAGCGGCGAACATCACGTACAACCTCCTGAAGATGATCGGCGGCGAAGGCGTGACGGTTGGC
CCGTTCCTGCTGGGCGCGGAAAAGCCGGTGCACATCCTGACGCCGGCGGCGACCGTGCGCCGGATCATCAACATGACGGC
GGTGGCTTCGGCCAACGCGCGCAAGCCGGCGAACGCGAAGTAA

Upstream 100 bases:

>100_bases
ATGCGCAAGCCGCCTCGGTCGATTATCCATTCGATAGATGTAAGCGACGCCGATGGTGCGGTGTGCCGGGCTCAATTACT
TACGTCTCGCAGGTCAGAAA

Downstream 100 bases:

>100_bases
TGCAGATGCCTTGAGGATTGAAGCGGCGCCTCGCCGAGGTGCCGGCTACGAGCCTGCCAGAACGCCACGGAAGTTGATTC
CGTGGCGTTTTTTGTATGCG

Product: malic enzyme

Products: NA

Alternate protein names: NADP-ME [H]

Number of amino acids: Translated: 760; Mature: 760

Protein sequence:

>760_residues
MDEQLKQSALAYHQNPKPGKISVTPTKPLSNQLDLSLAYSPGVAAACMAIYDEPLDAQKYTSRGNLVGVITNGTAVLGLG
NIGPLAAKPVMEGKGCLFKKFAGIDVFDIELSESDPDKLVEAIAMLEPTLGGINLEDIKAPECFYIEKKLRERMKIPVFH
DDQHGTAIIASAAILNGLKVVGKKLGEVKLVCSGAGAAAIACLDLLVNLGLSKKNILVTDSKGVIYEGRGNLDPSKERYA
ANTGARTLADAIRGADVFLGCSSAGVLKPEMVAEMGTQPLILALANPEPEIRPEDAKKVRPDCIIATGRSDYPNQVNNVL
CFPFIFRGALDVGATTITEEMKLACVRAIAELAEETDQGDEVAKAYEGHSLEFGPEYLIPKPFDPRLIIKIAPAVAQAAM
DSGVATRPIKDMDAYREELGTTVYRTGMVMRPVFAAAKSEPARIVFAEGEDERVLRAAQFVLLEKIARPILVGRPSVIEM
RLKKMGSKLKCGDDFEVVDPEDDPRYQQSWQAYHELGAREGVTPDVAKAAMRKFNTLIGAILVRLGEADGMICGMIGQYH
THLKFIEQVLGKAENVQNFAAMNLLMLPGRNLFICDTYVNETPTAEQLADMTMLAAGEIEKFGITPKVALLSNSNFGSAP
SSSSQRMAAARKLIVERAPTLEIDGEMHGDAALSEAVRKAAFPGTTLSGEANLLIMPNVEAANITYNLLKMIGGEGVTVG
PFLLGAEKPVHILTPAATVRRIINMTAVASANARKPANAK

Sequences:

>Translated_760_residues
MDEQLKQSALAYHQNPKPGKISVTPTKPLSNQLDLSLAYSPGVAAACMAIYDEPLDAQKYTSRGNLVGVITNGTAVLGLG
NIGPLAAKPVMEGKGCLFKKFAGIDVFDIELSESDPDKLVEAIAMLEPTLGGINLEDIKAPECFYIEKKLRERMKIPVFH
DDQHGTAIIASAAILNGLKVVGKKLGEVKLVCSGAGAAAIACLDLLVNLGLSKKNILVTDSKGVIYEGRGNLDPSKERYA
ANTGARTLADAIRGADVFLGCSSAGVLKPEMVAEMGTQPLILALANPEPEIRPEDAKKVRPDCIIATGRSDYPNQVNNVL
CFPFIFRGALDVGATTITEEMKLACVRAIAELAEETDQGDEVAKAYEGHSLEFGPEYLIPKPFDPRLIIKIAPAVAQAAM
DSGVATRPIKDMDAYREELGTTVYRTGMVMRPVFAAAKSEPARIVFAEGEDERVLRAAQFVLLEKIARPILVGRPSVIEM
RLKKMGSKLKCGDDFEVVDPEDDPRYQQSWQAYHELGAREGVTPDVAKAAMRKFNTLIGAILVRLGEADGMICGMIGQYH
THLKFIEQVLGKAENVQNFAAMNLLMLPGRNLFICDTYVNETPTAEQLADMTMLAAGEIEKFGITPKVALLSNSNFGSAP
SSSSQRMAAARKLIVERAPTLEIDGEMHGDAALSEAVRKAAFPGTTLSGEANLLIMPNVEAANITYNLLKMIGGEGVTVG
PFLLGAEKPVHILTPAATVRRIINMTAVASANARKPANAK
>Mature_760_residues
MDEQLKQSALAYHQNPKPGKISVTPTKPLSNQLDLSLAYSPGVAAACMAIYDEPLDAQKYTSRGNLVGVITNGTAVLGLG
NIGPLAAKPVMEGKGCLFKKFAGIDVFDIELSESDPDKLVEAIAMLEPTLGGINLEDIKAPECFYIEKKLRERMKIPVFH
DDQHGTAIIASAAILNGLKVVGKKLGEVKLVCSGAGAAAIACLDLLVNLGLSKKNILVTDSKGVIYEGRGNLDPSKERYA
ANTGARTLADAIRGADVFLGCSSAGVLKPEMVAEMGTQPLILALANPEPEIRPEDAKKVRPDCIIATGRSDYPNQVNNVL
CFPFIFRGALDVGATTITEEMKLACVRAIAELAEETDQGDEVAKAYEGHSLEFGPEYLIPKPFDPRLIIKIAPAVAQAAM
DSGVATRPIKDMDAYREELGTTVYRTGMVMRPVFAAAKSEPARIVFAEGEDERVLRAAQFVLLEKIARPILVGRPSVIEM
RLKKMGSKLKCGDDFEVVDPEDDPRYQQSWQAYHELGAREGVTPDVAKAAMRKFNTLIGAILVRLGEADGMICGMIGQYH
THLKFIEQVLGKAENVQNFAAMNLLMLPGRNLFICDTYVNETPTAEQLADMTMLAAGEIEKFGITPKVALLSNSNFGSAP
SSSSQRMAAARKLIVERAPTLEIDGEMHGDAALSEAVRKAAFPGTTLSGEANLLIMPNVEAANITYNLLKMIGGEGVTVG
PFLLGAEKPVHILTPAATVRRIINMTAVASANARKPANAK

Specific function: Unknown

COG id: COG0281

COG function: function code C; Malic enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family [H]

Homologues:

Organism=Homo sapiens, GI4505143, Length=358, Percent_Identity=27.6536312849162, Blast_Score=87, Evalue=7e-17,
Organism=Homo sapiens, GI62420882, Length=348, Percent_Identity=27.0114942528736, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI62420880, Length=348, Percent_Identity=27.0114942528736, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI239049447, Length=348, Percent_Identity=27.0114942528736, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI4505145, Length=350, Percent_Identity=27.1428571428571, Blast_Score=73, Evalue=1e-12,
Organism=Homo sapiens, GI270265879, Length=317, Percent_Identity=28.391167192429, Blast_Score=70, Evalue=7e-12,
Organism=Escherichia coli, GI1788806, Length=756, Percent_Identity=63.3597883597884, Blast_Score=981, Evalue=0.0,
Organism=Escherichia coli, GI1788800, Length=316, Percent_Identity=32.5949367088608, Blast_Score=141, Evalue=2e-34,
Organism=Escherichia coli, GI1788635, Length=349, Percent_Identity=30.0859598853868, Blast_Score=139, Evalue=8e-34,
Organism=Escherichia coli, GI87081919, Length=411, Percent_Identity=23.1143552311436, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322823, Length=268, Percent_Identity=28.7313432835821, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281362674, Length=491, Percent_Identity=26.6802443991853, Blast_Score=94, Evalue=5e-19,
Organism=Drosophila melanogaster, GI21356279, Length=491, Percent_Identity=26.6802443991853, Blast_Score=93, Evalue=6e-19,
Organism=Drosophila melanogaster, GI281362672, Length=491, Percent_Identity=26.6802443991853, Blast_Score=93, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24646388, Length=352, Percent_Identity=28.6931818181818, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24646386, Length=352, Percent_Identity=28.6931818181818, Blast_Score=87, Evalue=5e-17,
Organism=Drosophila melanogaster, GI78707242, Length=409, Percent_Identity=23.7163814180929, Blast_Score=67, Evalue=5e-11,
Organism=Drosophila melanogaster, GI78707238, Length=409, Percent_Identity=23.7163814180929, Blast_Score=67, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015884
- InterPro:   IPR012301
- InterPro:   IPR012302
- InterPro:   IPR012188
- InterPro:   IPR016040
- InterPro:   IPR002505 [H]

Pfam domain/function: PF00390 malic; PF03949 Malic_M; PF01515 PTA_PTB [H]

EC number: =1.1.1.40 [H]

Molecular weight: Translated: 81542; Mature: 81542

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEQLKQSALAYHQNPKPGKISVTPTKPLSNQLDLSLAYSPGVAAACMAIYDEPLDAQKY
CCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCCHHHH
TSRGNLVGVITNGTAVLGLGNIGPLAAKPVMEGKGCLFKKFAGIDVFDIELSESDPDKLV
CCCCCEEEEEECCEEEEEECCCCCCCCCCCCCCCCCHHHHHCCCEEEEEEECCCCHHHHH
EAIAMLEPTLGGINLEDIKAPECFYIEKKLRERMKIPVFHDDQHGTAIIASAAILNGLKV
HHHHHHCCCCCCCCHHHCCCCCHHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHHH
VGKKLGEVKLVCSGAGAAAIACLDLLVNLGLSKKNILVTDSKGVIYEGRGNLDPSKERYA
HHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEECCCCEEECCCCCCCCCHHHHH
ANTGARTLADAIRGADVFLGCSSAGVLKPEMVAEMGTQPLILALANPEPEIRPEDAKKVR
CCCCHHHHHHHHCCCEEEEECCCCCCCCHHHHHHCCCCCEEEEECCCCCCCCCCHHHHCC
PDCIIATGRSDYPNQVNNVLCFPFIFRGALDVGATTITEEMKLACVRAIAELAEETDQGD
CCEEEECCCCCCCHHHCCEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCH
EVAKAYEGHSLEFGPEYLIPKPFDPRLIIKIAPAVAQAAMDSGVATRPIKDMDAYREELG
HHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHCCCCCCCHHHHHHHHHHHC
TTVYRTGMVMRPVFAAAKSEPARIVFAEGEDERVLRAAQFVLLEKIARPILVGRPSVIEM
CHHHHCCCHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
RLKKMGSKLKCGDDFEVVDPEDDPRYQQSWQAYHELGAREGVTPDVAKAAMRKFNTLIGA
HHHHCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
ILVRLGEADGMICGMIGQYHTHLKFIEQVLGKAENVQNFAAMNLLMLPGRNLFICDTYVN
HHHHHCCCCCEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEEEEECCCCEEEEECCCC
ETPTAEQLADMTMLAAGEIEKFGITPKVALLSNSNFGSAPSSSSQRMAAARKLIVERAPT
CCCCHHHHHHHHHHHHCCHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCC
LEIDGEMHGDAALSEAVRKAAFPGTTLSGEANLLIMPNVEAANITYNLLKMIGGEGVTVG
EEECCCCCCHHHHHHHHHHHCCCCCEECCCCCEEEECCCCHHHHHHHHHHHHCCCCCEEC
PFLLGAEKPVHILTPAATVRRIINMTAVASANARKPANAK
CEEECCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MDEQLKQSALAYHQNPKPGKISVTPTKPLSNQLDLSLAYSPGVAAACMAIYDEPLDAQKY
CCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCCHHHH
TSRGNLVGVITNGTAVLGLGNIGPLAAKPVMEGKGCLFKKFAGIDVFDIELSESDPDKLV
CCCCCEEEEEECCEEEEEECCCCCCCCCCCCCCCCCHHHHHCCCEEEEEEECCCCHHHHH
EAIAMLEPTLGGINLEDIKAPECFYIEKKLRERMKIPVFHDDQHGTAIIASAAILNGLKV
HHHHHHCCCCCCCCHHHCCCCCHHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHHH
VGKKLGEVKLVCSGAGAAAIACLDLLVNLGLSKKNILVTDSKGVIYEGRGNLDPSKERYA
HHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEECCCCEEECCCCCCCCCHHHHH
ANTGARTLADAIRGADVFLGCSSAGVLKPEMVAEMGTQPLILALANPEPEIRPEDAKKVR
CCCCHHHHHHHHCCCEEEEECCCCCCCCHHHHHHCCCCCEEEEECCCCCCCCCCHHHHCC
PDCIIATGRSDYPNQVNNVLCFPFIFRGALDVGATTITEEMKLACVRAIAELAEETDQGD
CCEEEECCCCCCCHHHCCEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCH
EVAKAYEGHSLEFGPEYLIPKPFDPRLIIKIAPAVAQAAMDSGVATRPIKDMDAYREELG
HHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHCCCCCCCHHHHHHHHHHHC
TTVYRTGMVMRPVFAAAKSEPARIVFAEGEDERVLRAAQFVLLEKIARPILVGRPSVIEM
CHHHHCCCHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
RLKKMGSKLKCGDDFEVVDPEDDPRYQQSWQAYHELGAREGVTPDVAKAAMRKFNTLIGA
HHHHCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
ILVRLGEADGMICGMIGQYHTHLKFIEQVLGKAENVQNFAAMNLLMLPGRNLFICDTYVN
HHHHHCCCCCEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEEEEECCCCEEEEECCCC
ETPTAEQLADMTMLAAGEIEKFGITPKVALLSNSNFGSAPSSSSQRMAAARKLIVERAPT
CCCCHHHHHHHHHHHHCCHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCC
LEIDGEMHGDAALSEAVRKAAFPGTTLSGEANLLIMPNVEAANITYNLLKMIGGEGVTVG
EEECCCCCCHHHHHHHHHHHCCCCCEECCCCCEEEECCCCHHHHHHHHHHHHCCCCCEEC
PFLLGAEKPVHILTPAATVRRIINMTAVASANARKPANAK
CEEECCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 36376 [H]