Click here to switch to the map view.

The map label for this gene is lrp [H]

Identifier: 91785492

GI number: 91785492

Start: 4551097

End: 4551594

Strand: Reverse

Name: lrp [H]

Synonym: Bxe_A0287

Alternate gene names: 91785492

Gene position: 4551594-4551097 (Counterclockwise)

Preceding gene: 91785496

Following gene: 91785483

Centisome position: 92.97

GC content: 60.64

Gene sequence:

>498_bases
ATGGCCAATATAGAGATAGATGCCATCGACAGGCGGATTCTGGCGATCCTGCAGGAGAATGGCCGGCTGTCGAACCAGGA
GATCGCCGAGCGCGTCAATCTTTCGCCGAGTCCGTGTCTACGGCGTATCCGCCGGCTGGAAGAGAGCGGCGTGATCCGCA
GCTATGTCGCGTTGCTCGACGCGCAGCGGCTCGGGCTCGACTTGCTCGCGTATGTGAATGTGCGGTTGGAAAAACGCGGT
GGTTCGGCGCTCAGCCCGCGTGGCGACGCGACCCACGCCGATCTGTTTCGCGCGGCCGTTCAGGCGTGGCCCGAAGTGGT
GGCGTGCCATGCAATGACCGGCGAGATGGACTATCTGCTGCGTGTTCAAGTGGAGGATATGGCGCACTTTTCGCGCTTTG
TGCAGGACCAGTTGCTGCACCATCCATCCGTGATCGACGTGAAAACGAGCTTCTCGCTCGAAAAGATCAAGGAGACGACG
GCGCTGCCGATCTTGTGA

Upstream 100 bases:

>100_bases
AAGTGTAAAGGCCTGCTTGCGACGAAAACTTGCGAACTTAATCGCGTACCGATACGCTGACGCTATTTTCTAGCTCGATA
GACCGAACGGACGGCAGAAA

Downstream 100 bases:

>100_bases
GGCGCCGCCGCGCGCGCAGGCGCTCGATAAAAAAAGGGCAGTTCACTCGTGAACTGCCCTTTTTTGTGAACCGCGAAGCT
ATCAGGCTGCAGCCGCAACC

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MANIEIDAIDRRILAILQENGRLSNQEIAERVNLSPSPCLRRIRRLEESGVIRSYVALLDAQRLGLDLLAYVNVRLEKRG
GSALSPRGDATHADLFRAAVQAWPEVVACHAMTGEMDYLLRVQVEDMAHFSRFVQDQLLHHPSVIDVKTSFSLEKIKETT
ALPIL

Sequences:

>Translated_165_residues
MANIEIDAIDRRILAILQENGRLSNQEIAERVNLSPSPCLRRIRRLEESGVIRSYVALLDAQRLGLDLLAYVNVRLEKRG
GSALSPRGDATHADLFRAAVQAWPEVVACHAMTGEMDYLLRVQVEDMAHFSRFVQDQLLHHPSVIDVKTSFSLEKIKETT
ALPIL
>Mature_164_residues
ANIEIDAIDRRILAILQENGRLSNQEIAERVNLSPSPCLRRIRRLEESGVIRSYVALLDAQRLGLDLLAYVNVRLEKRGG
SALSPRGDATHADLFRAAVQAWPEVVACHAMTGEMDYLLRVQVEDMAHFSRFVQDQLLHHPSVIDVKTSFSLEKIKETTA
LPIL

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=160, Percent_Identity=40, Blast_Score=124, Evalue=2e-30,
Organism=Escherichia coli, GI87081742, Length=159, Percent_Identity=40.251572327044, Blast_Score=124, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 18556; Mature: 18424

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANIEIDAIDRRILAILQENGRLSNQEIAERVNLSPSPCLRRIRRLEESGVIRSYVALLD
CCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHH
AQRLGLDLLAYVNVRLEKRGGSALSPRGDATHADLFRAAVQAWPEVVACHAMTGEMDYLL
HHHHHHHHHHHHHHEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHE
RVQVEDMAHFSRFVQDQLLHHPSVIDVKTSFSLEKIKETTALPIL
EEHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCCCC
>Mature Secondary Structure 
ANIEIDAIDRRILAILQENGRLSNQEIAERVNLSPSPCLRRIRRLEESGVIRSYVALLD
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHH
AQRLGLDLLAYVNVRLEKRGGSALSPRGDATHADLFRAAVQAWPEVVACHAMTGEMDYLL
HHHHHHHHHHHHHHEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHE
RVQVEDMAHFSRFVQDQLLHHPSVIDVKTSFSLEKIKETTALPIL
EEHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]