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The map label for this gene is rpoC [H]

Identifier: 91785472

GI number: 91785472

Start: 4521677

End: 4525915

Strand: Reverse

Name: rpoC [H]

Synonym: Bxe_A0307

Alternate gene names: 91785472

Gene position: 4525915-4521677 (Counterclockwise)

Preceding gene: 91785473

Following gene: 91785471

Centisome position: 92.44

GC content: 59.92

Gene sequence:

>4239_bases
ATGAAAGCTCTGCTCGATCTATTCAAGCAAGTCCAACAGCCTGAAGTTTTTGACGCGATCAAGATCGGTCTGGCTTCGCC
GGACAAGATCCGTTCGTGGTCGTTCGGTGAAGTGAAGAAGCCGGAAACCATCAACTACCGGACGTTCAAGCCGGAACGCG
ATGGTTTGTTCTGCGCGAAGATCTTCGGGCCGATCAAAGACTACGAATGTCTTTGCGGTAAGTACAAGCGCCTGAAGCAT
CGTGGCGTGATCTGCGAGAAGTGCGGCGTCGAAGTGACGCTGGCGAAAGTGCGTCGCGAACGCATGGGCCACATCGAACT
GGCCTCGCCGGTTGCGCACATCTGGTTTTTGAAGTCGCTGCCGTCGCGTCTGGGCATGGTGCTCGACATGACGCTGCGCG
ATATCGAACGCGTGCTGTATTTCGAAGCATACGTGGTGATCGATCCGGGCATGACGCCGCTGAAAGCGCGGCAGATCATG
ACGGAAGAGGATTACTACAACAAGGTCGAAGAATACGGTGACGAATTCCGTGCCGAGATGGGCGCGGAAGGCGTGCGCGA
GCTGCTGCGCGCGATCAACATCGACGAACAGGTCGAGATGCTGCGCACCGAACTCAAGAACACGGGTTCGGAAGCGAAGA
TCAAGAAGTACGCGAAGCGCCTGAAGGTGCTCGAGGCTTTCCAGCGTTCGGGCATCAAGCCTGACTGGATGGTGCTCGAA
GTGCTGCCGGTGCTGCCGCCGGAACTGCGTCCGCTGGTGCCGCTCGACGGCGGCCGCTTCGCGACGTCGGACCTGAACGA
CCTGTATCGCCGCGTGATCAACCGTAACAACCGGTTGAAGCGTCTGCTCGAACTGAAGGCGCCTGAAATCATCGTCCGCA
ACGAAAAGCGGATGCTGCAGGAAGCCGTCGATTCGCTGCTCGACAACGGTCGCCGCGGTAAGGCCATGACCGGCGCGAAC
AAGCGTCCGCTGAAGTCGCTCGCTGACATGATCAAGGGTAAGGGCGGTCGTTTCCGTCAGAACCTGCTTGGTAAGCGCGT
CGACTATTCGGGCCGTTCGGTGATCGTGGTCGGCCCGACGCTCAAGCTGCATCAGTGCGGTCTGCCGAAGCTGATGGCGC
TCGAACTGTTCAAGCCGTTCATCTTCAACAAGCTCGAAGTGATGGGTGTCGCTACCACCATCAAGGCCGCGAAGAAGGAA
GTCGAGAACCAGACGCCGGTGGTGTGGGACATTCTCGAAGAAGTCATTCGTGAACATCCGGTCATGCTGAACCGTGCGCC
TACGCTTCACCGTCTCGGCATTCAGGCTTTCGAGCCGGTGCTGATCGAAGGTAAGGCTATCCAGTTGCATCCGCTCGTTT
GCGCGGCGTTCAACGCCGACTTCGACGGTGACCAGATGGCTGTTCACGTGCCGCTGTCGCTGGAAGCGCAGATGGAAGCG
CGTACGTTGATGCTGGCGTCGAACAACATTCTGTTCCCGGCCAACGGCGATCCGTCGATCGTGCCGTCGCAGGATATCGT
GCTCGGTCTGTACTACGCGACCCGTGAAGCAGTGAACGCCAAGGGCGAAGGTCTGACGTTCACCGGCGTTTCGGAAGCGT
TGCGTGCGTACGAGAACAAGGAAGTCGAGCTGGCCTCGCGCGTCAACGTGCGGATCACGGAAATGGTCCATAACGAAGAC
AAGTCGGACGGTGCGCCGGCGTTCGTGCCGAAGATCTCGCTGTACGCGACCACCGTCGGCCGCGCAATCCTGTCGGAAAT
CCTTCCGCCGGGCCTGCCGTTTTCGGTGCTCAACAAGCCGCTGAAGAAGAAGGAAATCTCGCGCCTCATCAACACCGCAT
TCCGCAAGTGCGGTCTGCGTGAAACGGTGATTTTCGCCGACCAGTTGATGCAGTCGGGTTTCCGTCTGGCAACGCGCGCT
GGTATCTCGATCTGCGTCGACGACATGCTCGTGCCGCCGCAGAAGGAAACCATCGTTGGCGACGCCGCGAAGAAGGTGAA
GGAATACGACCGTCAGTACATGTCGGGTCTCGTCACGTCGCAAGAGCGCTACAACAACGTGGTCGACATCTGGTCGGCAA
CGTCGGAAGCGGTCGGCAAGGCGATGATGGAACAGTTGTCGACGGAACCGGTCACGGATCGCGACGGCAACGAAACGCGT
CAGGAATCGTTCAACTCGATTTACATGATGGCGGACTCGGGTGCTCGTGGTTCCGCGGTTCAGATTCGTCAGCTGGCCGG
TATGCGTGGCCTGATGGCGAAGCCGGACGGCTCGATCATCGAGACGCCGATTACGGCGAACTTCCGTGAAGGCCTGAACG
TGTTGCAGTACTTCATCTCGACCCACGGCGCACGTAAGGGTCTGGCTGATACGGCACTGAAGACGGCGAACTCGGGTTAC
CTGACGCGTCGTCTCGTGGACGTGACGCAGGATCTGGTGGTGGTCGAGGACGATTGCGGTACGTCCAACGGCGTTGCCAT
GAAGGCGTTGGTCGAAGGCGGTGAAGTCGTCGAAGCGCTGCGTGACCGTATTCTCGGTCGCGTGACGGTGGCTGACGTCG
TCAATCCGGAATCGCAGGAAACCCTGTACGAAACGGGCACGTTGCTCGACGAAGATGCGGTCGAAGAAATCGAACGCCTC
GGCATCGACGAAGTGCGCGTGCGTACGCCGCTGACTTGCGAGACGCGTTACGGTCTGTGCGCAGCCTGCTACGGCCGCGA
CCTGGGCCGCGGCTCGTCGGTCAACGTCGGTGAAGCAGTCGGCGTGATCGCTGCTCAGTCGATCGGTGAACCGGGCACGC
AGCTTACGATGCGTACGTTCCACATCGGTGGTGCGGCATCGCGTGCGGCAGTGGCTTCGTCGGTTGAAGCGAAGTCGAAC
GGTACGGTGCGTTTCACCGCAACCATGCGTTACGTCACCAACGCGAAGGGCGAGCAGATCGTCATCTCGCGTTCGGGCGA
AGCGATGATCACCGACGACCACGGTCGCGAGCGCGAACGTCACAAGGTGCCGTACGGCGCGACGCTGTTGCAACTGGACG
GCGCGCAGATCAAGGCCGGCACGCAACTGGCCACGTGGGACCCGATGACGCGTCCGATCATCACCGAGTACGGTGGTACG
GTGAAGTTCGAAAACGTCGAAGAAGGCGTGACGGTTGCCAAGCAGATCGACGACGTGACGGGTCTGTCCACGCTGGTCGT
GATCGACGTGAAGCGTCGTGGTTCGCAAGCGTCGAAGACGGTGCGTCCGCAGGTCAAGCTGCTCGATGCGAACGGCGAAG
AAGTCAAGATCCCGAACACCGAGCACTCGGTGCAGATCGGCTTCCAGGTCGGCGCTCTGATCACCGTGAAGGATGGTCAG
CAAGTGCAGGTCGGTGAAGTGCTCGCACGGATCCCGACTGAATCGCAGAAGACGCGTGACATTACCGGCGGTCTGCCGCG
TGTGGCGGAACTGTTCGAAGCACGTTCGCCGAAGGACGCAGGTATCCTGGCGGAAGTCACGGGTACGACGTCGTTCGGTA
AGGACACGAAGGGCAAGCAGCGTCTCGTTATCACGGACCTCGAGGGCAACCAGCACGAGTTCCTGATCGCGAAGGAAAAG
CAGGTTCTGGTGCACGATGGTCAGGTCGTCAACAAGGGCGAAATGATCGTCGACGGGCCGGCGGATCCGCACGACATTCT
GCGTTTGCAGGGCGTCGAAGCGCTGTCGCGTTACATCGTGGACGAAGTGCAGGACGTGTACCGTCTGCAAGGCGTGAAGA
TCAACGACAAGCACATTGAAGTGATTGTTCGTCAGATGCTGCGCCGCGTGCAGATTACGGACAACGGCGATACGCGTTTC
ATCCCGGGCGAACAGGTCGAGCGGTCGGATATGCTCGACGAGAACGACCGTATGATCGCGGAAGACAAGCGTCCGGCAAC
GTACGAAAACGTGCTGCTCGGTATCACGAAGGCCTCGTTGTCGACCGATTCGTTCATCTCGGCGGCGTCGTTCCAGGAAA
CGACGCGCGTGCTGACCGAAGCGGCGATCATGGGCAAGCGCGACGACCTGCGTGGTCTGAAGGAAAACGTGATCGTCGGC
CGTCTGATTCCGGCCGGTACGGGTCTCGCGTTCCACAAGGCACGCAAGAGCAAGGAACTGTCCGACCGCGAGCGTTTCGA
TCAGATCGCAGCGGAAGAGTCGTTCGAATTCGGTACGCCGGAAACTCCGGCCGCCGAACAGCAGCACTCAGGCGAGTAA

Upstream 100 bases:

>100_bases
CGGCATGCCGGAATCCTTCAACGTGTTGGTGAAGGAAATCCGCTCGCTCGGTATCGATATCGACCTCGACCGCAACTAAT
CGGACTACGGAGAGAAAGCA

Downstream 100 bases:

>100_bases
GCTCAGGTCAGTGGCCGAGGCGGCACAAGCCGCCTCGGCTCACCAGCCAGCGAAGCCGCTCAGTTTCGACTGAGCGGCTT
TTTTTATGCGCTTTCTTTTT

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta' [H]

Number of amino acids: Translated: 1412; Mature: 1412

Protein sequence:

>1412_residues
MKALLDLFKQVQQPEVFDAIKIGLASPDKIRSWSFGEVKKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKH
RGVICEKCGVEVTLAKVRRERMGHIELASPVAHIWFLKSLPSRLGMVLDMTLRDIERVLYFEAYVVIDPGMTPLKARQIM
TEEDYYNKVEEYGDEFRAEMGAEGVRELLRAINIDEQVEMLRTELKNTGSEAKIKKYAKRLKVLEAFQRSGIKPDWMVLE
VLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPEIIVRNEKRMLQEAVDSLLDNGRRGKAMTGAN
KRPLKSLADMIKGKGGRFRQNLLGKRVDYSGRSVIVVGPTLKLHQCGLPKLMALELFKPFIFNKLEVMGVATTIKAAKKE
VENQTPVVWDILEEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQMEA
RTLMLASNNILFPANGDPSIVPSQDIVLGLYYATREAVNAKGEGLTFTGVSEALRAYENKEVELASRVNVRITEMVHNED
KSDGAPAFVPKISLYATTVGRAILSEILPPGLPFSVLNKPLKKKEISRLINTAFRKCGLRETVIFADQLMQSGFRLATRA
GISICVDDMLVPPQKETIVGDAAKKVKEYDRQYMSGLVTSQERYNNVVDIWSATSEAVGKAMMEQLSTEPVTDRDGNETR
QESFNSIYMMADSGARGSAVQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGY
LTRRLVDVTQDLVVVEDDCGTSNGVAMKALVEGGEVVEALRDRILGRVTVADVVNPESQETLYETGTLLDEDAVEEIERL
GIDEVRVRTPLTCETRYGLCAACYGRDLGRGSSVNVGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAVASSVEAKSN
GTVRFTATMRYVTNAKGEQIVISRSGEAMITDDHGRERERHKVPYGATLLQLDGAQIKAGTQLATWDPMTRPIITEYGGT
VKFENVEEGVTVAKQIDDVTGLSTLVVIDVKRRGSQASKTVRPQVKLLDANGEEVKIPNTEHSVQIGFQVGALITVKDGQ
QVQVGEVLARIPTESQKTRDITGGLPRVAELFEARSPKDAGILAEVTGTTSFGKDTKGKQRLVITDLEGNQHEFLIAKEK
QVLVHDGQVVNKGEMIVDGPADPHDILRLQGVEALSRYIVDEVQDVYRLQGVKINDKHIEVIVRQMLRRVQITDNGDTRF
IPGEQVERSDMLDENDRMIAEDKRPATYENVLLGITKASLSTDSFISAASFQETTRVLTEAAIMGKRDDLRGLKENVIVG
RLIPAGTGLAFHKARKSKELSDRERFDQIAAEESFEFGTPETPAAEQQHSGE

Sequences:

>Translated_1412_residues
MKALLDLFKQVQQPEVFDAIKIGLASPDKIRSWSFGEVKKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKH
RGVICEKCGVEVTLAKVRRERMGHIELASPVAHIWFLKSLPSRLGMVLDMTLRDIERVLYFEAYVVIDPGMTPLKARQIM
TEEDYYNKVEEYGDEFRAEMGAEGVRELLRAINIDEQVEMLRTELKNTGSEAKIKKYAKRLKVLEAFQRSGIKPDWMVLE
VLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPEIIVRNEKRMLQEAVDSLLDNGRRGKAMTGAN
KRPLKSLADMIKGKGGRFRQNLLGKRVDYSGRSVIVVGPTLKLHQCGLPKLMALELFKPFIFNKLEVMGVATTIKAAKKE
VENQTPVVWDILEEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQMEA
RTLMLASNNILFPANGDPSIVPSQDIVLGLYYATREAVNAKGEGLTFTGVSEALRAYENKEVELASRVNVRITEMVHNED
KSDGAPAFVPKISLYATTVGRAILSEILPPGLPFSVLNKPLKKKEISRLINTAFRKCGLRETVIFADQLMQSGFRLATRA
GISICVDDMLVPPQKETIVGDAAKKVKEYDRQYMSGLVTSQERYNNVVDIWSATSEAVGKAMMEQLSTEPVTDRDGNETR
QESFNSIYMMADSGARGSAVQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGY
LTRRLVDVTQDLVVVEDDCGTSNGVAMKALVEGGEVVEALRDRILGRVTVADVVNPESQETLYETGTLLDEDAVEEIERL
GIDEVRVRTPLTCETRYGLCAACYGRDLGRGSSVNVGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAVASSVEAKSN
GTVRFTATMRYVTNAKGEQIVISRSGEAMITDDHGRERERHKVPYGATLLQLDGAQIKAGTQLATWDPMTRPIITEYGGT
VKFENVEEGVTVAKQIDDVTGLSTLVVIDVKRRGSQASKTVRPQVKLLDANGEEVKIPNTEHSVQIGFQVGALITVKDGQ
QVQVGEVLARIPTESQKTRDITGGLPRVAELFEARSPKDAGILAEVTGTTSFGKDTKGKQRLVITDLEGNQHEFLIAKEK
QVLVHDGQVVNKGEMIVDGPADPHDILRLQGVEALSRYIVDEVQDVYRLQGVKINDKHIEVIVRQMLRRVQITDNGDTRF
IPGEQVERSDMLDENDRMIAEDKRPATYENVLLGITKASLSTDSFISAASFQETTRVLTEAAIMGKRDDLRGLKENVIVG
RLIPAGTGLAFHKARKSKELSDRERFDQIAAEESFEFGTPETPAAEQQHSGE
>Mature_1412_residues
MKALLDLFKQVQQPEVFDAIKIGLASPDKIRSWSFGEVKKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKH
RGVICEKCGVEVTLAKVRRERMGHIELASPVAHIWFLKSLPSRLGMVLDMTLRDIERVLYFEAYVVIDPGMTPLKARQIM
TEEDYYNKVEEYGDEFRAEMGAEGVRELLRAINIDEQVEMLRTELKNTGSEAKIKKYAKRLKVLEAFQRSGIKPDWMVLE
VLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPEIIVRNEKRMLQEAVDSLLDNGRRGKAMTGAN
KRPLKSLADMIKGKGGRFRQNLLGKRVDYSGRSVIVVGPTLKLHQCGLPKLMALELFKPFIFNKLEVMGVATTIKAAKKE
VENQTPVVWDILEEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQMEA
RTLMLASNNILFPANGDPSIVPSQDIVLGLYYATREAVNAKGEGLTFTGVSEALRAYENKEVELASRVNVRITEMVHNED
KSDGAPAFVPKISLYATTVGRAILSEILPPGLPFSVLNKPLKKKEISRLINTAFRKCGLRETVIFADQLMQSGFRLATRA
GISICVDDMLVPPQKETIVGDAAKKVKEYDRQYMSGLVTSQERYNNVVDIWSATSEAVGKAMMEQLSTEPVTDRDGNETR
QESFNSIYMMADSGARGSAVQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGY
LTRRLVDVTQDLVVVEDDCGTSNGVAMKALVEGGEVVEALRDRILGRVTVADVVNPESQETLYETGTLLDEDAVEEIERL
GIDEVRVRTPLTCETRYGLCAACYGRDLGRGSSVNVGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAVASSVEAKSN
GTVRFTATMRYVTNAKGEQIVISRSGEAMITDDHGRERERHKVPYGATLLQLDGAQIKAGTQLATWDPMTRPIITEYGGT
VKFENVEEGVTVAKQIDDVTGLSTLVVIDVKRRGSQASKTVRPQVKLLDANGEEVKIPNTEHSVQIGFQVGALITVKDGQ
QVQVGEVLARIPTESQKTRDITGGLPRVAELFEARSPKDAGILAEVTGTTSFGKDTKGKQRLVITDLEGNQHEFLIAKEK
QVLVHDGQVVNKGEMIVDGPADPHDILRLQGVEALSRYIVDEVQDVYRLQGVKINDKHIEVIVRQMLRRVQITDNGDTRF
IPGEQVERSDMLDENDRMIAEDKRPATYENVLLGITKASLSTDSFISAASFQETTRVLTEAAIMGKRDDLRGLKENVIVG
RLIPAGTGLAFHKARKSKELSDRERFDQIAAEESFEFGTPETPAAEQQHSGE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family [H]

Homologues:

Organism=Homo sapiens, GI4505939, Length=941, Percent_Identity=22.8480340063762, Blast_Score=177, Evalue=9e-44,
Organism=Homo sapiens, GI39725938, Length=853, Percent_Identity=25.9085580304807, Blast_Score=176, Evalue=2e-43,
Organism=Homo sapiens, GI103471997, Length=225, Percent_Identity=31.1111111111111, Blast_Score=86, Evalue=2e-16,
Organism=Escherichia coli, GI2367335, Length=1376, Percent_Identity=66.8604651162791, Blast_Score=1872, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=931, Percent_Identity=24.1675617615467, Blast_Score=172, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI25145495, Length=696, Percent_Identity=25.5747126436782, Blast_Score=169, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI71998295, Length=337, Percent_Identity=24.9258160237389, Blast_Score=89, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6320061, Length=894, Percent_Identity=23.9373601789709, Blast_Score=174, Evalue=9e-44,
Organism=Saccharomyces cerevisiae, GI6324690, Length=602, Percent_Identity=26.0797342192691, Blast_Score=155, Evalue=3e-38,
Organism=Drosophila melanogaster, GI17530899, Length=919, Percent_Identity=22.9597388465724, Blast_Score=170, Evalue=8e-42,
Organism=Drosophila melanogaster, GI281360912, Length=864, Percent_Identity=23.7268518518519, Blast_Score=157, Evalue=5e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754 [H]

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 156320; Mature: 156320

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALLDLFKQVQQPEVFDAIKIGLASPDKIRSWSFGEVKKPETINYRTFKPERDGLFCAK
CCHHHHHHHHHCCCHHHHHHHHCCCCCHHCCCCCCCCCCCCCCCCEEECCCCCCCEEEHH
IFGPIKDYECLCGKYKRLKHRGVICEKCGVEVTLAKVRRERMGHIELASPVAHIWFLKSL
HHCCCCHHHHHHHHHHHHHHCCCCHHHCCCEEHHHHHHHHHCCCEEHHHHHHHHHHHHHH
PSRLGMVLDMTLRDIERVLYFEAYVVIDPGMTPLKARQIMTEEDYYNKVEEYGDEFRAEM
HHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHH
GAEGVRELLRAINIDEQVEMLRTELKNTGSEAKIKKYAKRLKVLEAFQRSGIKPDWMVLE
CHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEHHH
VLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPEIIVRNEKRMLQ
HHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEECCHHHHHH
EAVDSLLDNGRRGKAMTGANKRPLKSLADMIKGKGGRFRQNLLGKRVDYSGRSVIVVGPT
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCEEEEECCC
LKLHQCGLPKLMALELFKPFIFNKLEVMGVATTIKAAKKEVENQTPVVWDILEEVIREHP
EEEHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
VMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQMEA
EEECCCCCHHHHCHHHCCCEEECCCEEEECCEEEEEECCCCCCCCEEEEECCCCCCCHHH
RTLMLASNNILFPANGDPSIVPSQDIVLGLYYATREAVNAKGEGLTFTGVSEALRAYENK
EEEEEECCCEEEECCCCCCCCCCCCCEEEEHHHHHHHHCCCCCCEEECCHHHHHHHHCCC
EVELASRVNVRITEMVHNEDKSDGAPAFVPKISLYATTVGRAILSEILPPGLPFSVLNKP
CEEEHHHCCEEEEEHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCC
LKKKEISRLINTAFRKCGLRETVIFADQLMQSGFRLATRAGISICVDDMLVPPQKETIVG
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHCCCCEEHHCCCCCCCCHHHHH
DAAKKVKEYDRQYMSGLVTSQERYNNVVDIWSATSEAVGKAMMEQLSTEPVTDRDGNETR
HHHHHHHHHHHHHHHHHHHCHHHHCCEEEHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHH
QESFNSIYMMADSGARGSAVQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFIS
HHCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHH
THGARKGLADTALKTANSGYLTRRLVDVTQDLVVVEDDCGTSNGVAMKALVEGGEVVEAL
HCCCCCCHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCCCCCCEEHHHHHCCHHHHHHH
RDRILGRVTVADVVNPESQETLYETGTLLDEDAVEEIERLGIDEVRVRTPLTCETRYGLC
HHHHHCCEEEHHHCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCEEECCCCEECCCCCHH
AACYGRDLGRGSSVNVGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAVASSVEAKSN
HHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHCCCCCC
GTVRFTATMRYVTNAKGEQIVISRSGEAMITDDHGRERERHKVPYGATLLQLDGAQIKAG
CEEEEEEEEEEECCCCCCEEEEECCCCEEEECCCCCCHHHHCCCCCCEEEEECCCEEECC
TQLATWDPMTRPIITEYGGTVKFENVEEGVTVAKQIDDVTGLSTLVVIDVKRRGSQASKT
CEEECCCCCCCCHHHHCCCEEEECCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHC
VRPQVKLLDANGEEVKIPNTEHSVQIGFQVGALITVKDGQQVQVGEVLARIPTESQKTRD
CCCEEEEEECCCCEEECCCCCCCEEEEEEEEEEEEECCCCEEHHHHHHHHCCCCCCCCCC
ITGGLPRVAELFEARSPKDAGILAEVTGTTSFGKDTKGKQRLVITDLEGNQHEFLIAKEK
CCCCCHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCEEEEEEECC
QVLVHDGQVVNKGEMIVDGPADPHDILRLQGVEALSRYIVDEVQDVYRLQGVKINDKHIE
EEEEECCEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHH
VIVRQMLRRVQITDNGDTRFIPGEQVERSDMLDENDRMIAEDKRPATYENVLLGITKASL
HHHHHHHHHEEECCCCCEECCCCCCCCHHHCCCCCCCEEECCCCCCCHHHHEEEEEHHCC
STDSFISAASFQETTRVLTEAAIMGKRDDLRGLKENVIVGRLIPAGTGLAFHKARKSKEL
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEEECCCCCHHHHHHHHCCCH
SDRERFDQIAAEESFEFGTPETPAAEQQHSGE
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKALLDLFKQVQQPEVFDAIKIGLASPDKIRSWSFGEVKKPETINYRTFKPERDGLFCAK
CCHHHHHHHHHCCCHHHHHHHHCCCCCHHCCCCCCCCCCCCCCCCEEECCCCCCCEEEHH
IFGPIKDYECLCGKYKRLKHRGVICEKCGVEVTLAKVRRERMGHIELASPVAHIWFLKSL
HHCCCCHHHHHHHHHHHHHHCCCCHHHCCCEEHHHHHHHHHCCCEEHHHHHHHHHHHHHH
PSRLGMVLDMTLRDIERVLYFEAYVVIDPGMTPLKARQIMTEEDYYNKVEEYGDEFRAEM
HHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHH
GAEGVRELLRAINIDEQVEMLRTELKNTGSEAKIKKYAKRLKVLEAFQRSGIKPDWMVLE
CHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEHHH
VLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPEIIVRNEKRMLQ
HHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEECCHHHHHH
EAVDSLLDNGRRGKAMTGANKRPLKSLADMIKGKGGRFRQNLLGKRVDYSGRSVIVVGPT
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCEEEEECCC
LKLHQCGLPKLMALELFKPFIFNKLEVMGVATTIKAAKKEVENQTPVVWDILEEVIREHP
EEEHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
VMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQMEA
EEECCCCCHHHHCHHHCCCEEECCCEEEECCEEEEEECCCCCCCCEEEEECCCCCCCHHH
RTLMLASNNILFPANGDPSIVPSQDIVLGLYYATREAVNAKGEGLTFTGVSEALRAYENK
EEEEEECCCEEEECCCCCCCCCCCCCEEEEHHHHHHHHCCCCCCEEECCHHHHHHHHCCC
EVELASRVNVRITEMVHNEDKSDGAPAFVPKISLYATTVGRAILSEILPPGLPFSVLNKP
CEEEHHHCCEEEEEHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCC
LKKKEISRLINTAFRKCGLRETVIFADQLMQSGFRLATRAGISICVDDMLVPPQKETIVG
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHCCCCEEHHCCCCCCCCHHHHH
DAAKKVKEYDRQYMSGLVTSQERYNNVVDIWSATSEAVGKAMMEQLSTEPVTDRDGNETR
HHHHHHHHHHHHHHHHHHHCHHHHCCEEEHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHH
QESFNSIYMMADSGARGSAVQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFIS
HHCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHH
THGARKGLADTALKTANSGYLTRRLVDVTQDLVVVEDDCGTSNGVAMKALVEGGEVVEAL
HCCCCCCHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCCCCCCEEHHHHHCCHHHHHHH
RDRILGRVTVADVVNPESQETLYETGTLLDEDAVEEIERLGIDEVRVRTPLTCETRYGLC
HHHHHCCEEEHHHCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCEEECCCCEECCCCCHH
AACYGRDLGRGSSVNVGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAVASSVEAKSN
HHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHCCCCCC
GTVRFTATMRYVTNAKGEQIVISRSGEAMITDDHGRERERHKVPYGATLLQLDGAQIKAG
CEEEEEEEEEEECCCCCCEEEEECCCCEEEECCCCCCHHHHCCCCCCEEEEECCCEEECC
TQLATWDPMTRPIITEYGGTVKFENVEEGVTVAKQIDDVTGLSTLVVIDVKRRGSQASKT
CEEECCCCCCCCHHHHCCCEEEECCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHC
VRPQVKLLDANGEEVKIPNTEHSVQIGFQVGALITVKDGQQVQVGEVLARIPTESQKTRD
CCCEEEEEECCCCEEECCCCCCCEEEEEEEEEEEEECCCCEEHHHHHHHHCCCCCCCCCC
ITGGLPRVAELFEARSPKDAGILAEVTGTTSFGKDTKGKQRLVITDLEGNQHEFLIAKEK
CCCCCHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCEEEEEEECC
QVLVHDGQVVNKGEMIVDGPADPHDILRLQGVEALSRYIVDEVQDVYRLQGVKINDKHIE
EEEEECCEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHH
VIVRQMLRRVQITDNGDTRFIPGEQVERSDMLDENDRMIAEDKRPATYENVLLGITKASL
HHHHHHHHHEEECCCCCEECCCCCCCCHHHCCCCCCCEEECCCCCCCHHHHEEEEEHHCC
STDSFISAASFQETTRVLTEAAIMGKRDDLRGLKENVIVGRLIPAGTGLAFHKARKSKEL
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEEECCCCCHHHHHHHHCCCH
SDRERFDQIAAEESFEFGTPETPAAEQQHSGE
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA