Click here to switch to the map view.

The map label for this gene is rpoB [H]

Identifier: 91785473

GI number: 91785473

Start: 4525937

End: 4530043

Strand: Reverse

Name: rpoB [H]

Synonym: Bxe_A0306

Alternate gene names: 91785473

Gene position: 4530043-4525937 (Counterclockwise)

Preceding gene: 91785474

Following gene: 91785472

Centisome position: 92.53

GC content: 59.58

Gene sequence:

>4107_bases
ATGCAATATTCCTTCACCGAGAAGAAGCGTATTCGCAAGAGTTTTGCGAAGCGCCCCATCGTTCACCAAGTACCTTTCCT
GCTGGCTACCCAGCTTGAATCATTCAGCACGTTTCTGCAAGCAGACACGTCGTCCACGCAACGCAAGCCGGAAGGCCTGC
AAGCTGCGTTTACCTCCGTTTTTCCCATTGTTTCGCATAACGGGTTCGCTCGTCTAGAGTTCGTCAGCTACATGCTGTCG
CCGCCGGCATTCAACATCAAGGAATGTCAGCAGCGCGGTTTGACCTATTGCTCGGCCCTGCGCGCGAAAGTGCGTCTGGT
GCTGCTCGACAAGGAATCCCCGAGCAAGCCGGTCGTCAAGGAAGTGAAGGAACAGGAAGTGTACATGGGCGAAATTCCGC
TCATGACGCCGACGGGTTCGTTCGTCATCAACGGCACGGAACGTGTGATCGTTTCGCAGCTGCACCGTTCGCCTGGCGTG
TTCTTCGAACACGACAAGGGCAAGACGCACAGCTCGGGCAAGCTGCTGTTCTCGGCACGTATCATTCCTTACCGCGGTTC
GTGGCTCGATTTTGAGTTCGACCCGAAGGATGTGCTGTACTTCCGCGTCGACCGCCGCCGCAAGATGCCGGTCACGATCC
TGCTGAAGGCAATCGGCCTCACGCCGGAACAGATCCTCGCAAACTTCTTCGTGTTCGACAATTTCACGCTGATGCCGGAA
GGCGCGCAGATGGAATTCGTGCCGGAGCGTTTGCGTGGTGAAGTCGCGCGTTTCGACATCACGGACCGTGACGGCAACGT
GATCGTCCAGAAGGACAAGCGGATCAACGCCAAGCACATTCGCGATCTCGACAACGCCAAGACCAAGTTCATCTCGGTCC
CGGAAGACTATTTGCTCGGCCGCGTGCTGGCGAAGAACGTGGTCGACGGCGACACGGGTGAAGTCATCGCTAACGCGAAC
GACGAAATCACGGAAACCGTGCTCGAGAAGCTGCGCGAGTCGAAGATCAAAGACATCCAGACGCTCTACACGAACGATCT
GGATCAAGGTCCGTACATCTCGTCGACACTGCGTATCGACGAAACCGCGGACAAGATGGCCGCGCGCATTGCAATTTACC
GCATGATGCGTCCGGGCGAGCCGCCGACCGAAGAAGCGGTCGAGGCGCTATTCAACCGTCTGTTCTACAGCGAAGACGCA
TACGACCTGTCCAAGGTGGGTCGTATGAAGTTCAATCGCCGTGTCGGCCGCGACGAAATCGTCGGTCCGATGACGCTGCA
AGACGACGATATCCTCGCCACGATCAAGATCCTGGTCGAGCTGCGTAACGGCAAGGGCGAAGTGGACGACATCGACCACT
TGGGCAATCGTCGTGTGCGTTGCGTCGGCGAACTGGCCGAAAACCAGTTCCGCGCCGGTCTCGTGCGTGTCGAACGTGCT
GTGAAGGAACGCCTCGGCCAGGCCGAAAGCGAAAACCTGATGCCGCACGATCTGATCAACTCGAAGCCGATTTCGTCGGC
GATTCGCGAGTTCTTCGGTTCGTCGCAGCTGTCGCAGTTCATGGACCAAACGAACCCGCTGTCGGAAATCACCCACAAGC
GCCGTGTTTCGGCTCTTGGCCCGGGCGGTTTGACGCGTGAGCGCGCCGGCTTTGAAGTCCGTGACGTGCATCCGACTCAC
TACGGTCGCGTGTGCCCGATTGAAACGCCGGAAGGTCCGAACATCGGCCTGATCAACTCGCTCGCTCTGTACGCGCACCT
GAACGAATACGGCTTCCTCGAAACGCCGTATCGCAAGGTCGTGGACAGCAAGGTGACCGATCAGATCGACTATCTGTCGG
CGATCGAAGAAGGCCGTTACGTGATCGCTCAGGCGAACGCGGCGGTGGCGGAAGACGGCTCGCTGACCGACGAACTGGTG
TCGTCGCGTGAAGCAGGCGAAACGCTGATGGTCACGCCGGACCGCATCCAGTACATGGACGTGGCGCCGTCGCAGATCGT
GTCGGTGGCAGCATCGCTGATTCCGTTCCTCGAGCACGATGACGCGAACCGCGCGTTGATGGGTTCGAACATGCAGCGTC
AGGCTGTGCCGTGTCTGCGTCCTGAAAAGGCCGTGGTCGGTACCGGTATCGAGCGCACGGTGGCAGTCGACTCGGGTACG
ACGGTTCAGGCATTCCGCGGTGGCGTGGTGGACTACGTCGACGCAGGCCGTATGGTGATCCGCGTGAACGATGACGAAGC
CGTTGCTGGCGACGTCGGCGTGGACATCTACAACCTGATCAAGTACACGCGTTCGAACCAGAACACGAACATCAACCAGC
GCCCGATCGTGAAGGTCGGCGACATCGTGTCGCGTGGCGACGTGCTGGCTGACGGCGCATCCACCGACCTCGGCGAACTG
GCTCTCGGCCAGAACATGCTGGTCGCGTTCATGCCGTGGAACGGCTACAACTTCGAAGACTCGATCCTGATCTCTGAGAA
GGTGGTTGCCGACGACCGTTACACGTCGATCCACATTGAAGAACTGAACGTCGTGGCTCGCGATACGAAGCTCGGACCGG
AAGAAATCACGCGCGACATCTCGAACCTGGCTGAAGTGCAACTCGGCCGTCTCGACGAGTCGGGCATCGTCTACATCGGC
GCTGAAGTCGAAGCAGGCGACGTGCTGGTCGGCAAGGTCACGCCGAAGGGCGAAACCCAGCTGACACCGGAAGAAAAGCT
GCTGCGCGCGATCTTCGGTGAGAAGGCTTCGGACGTGAAGGACACGTCGCTGCGCGTGCCGTCGGGCATGAGCGGCACCG
TGATCGACGTTCAAGTGTTCACGCGTGAAGGCATTCAGCGCGACAAGCGCGCGCAACAGATCATCGACGATGAACTGAAG
CGTTACCGCCTCGACCTGAACGACCAGCTGCGTATCGTGGAAGGCGACGCGTTCCAGCGTCTCGCACGTATGCTGACCGG
CAAGGTCGCGAACGGCGGTCCGAAGAAACTGGCGAAGGGCACGAAGATCGAACAGGCTTACCTGGAAGATCTGGATCACT
ACCACTGGTTCGACATCCGCCTCGCGGACGAAGAAGCAGCGGCACAGCTCGAAGCGATCAAGGACTCGATCGAACAGAAG
CGTCACCAGTTCGATCTGGCGTTCGAAGAAAAGCGCAAGAAACTCACGCAAGGCGACGAACTGCCGCCGGGCGTGTTGAA
GATGGTCAAGGTGTACCTGGCAGTCAAGCGCCGCCTGCAGCCTGGCGACAAGATGGCCGGCCGTCACGGTAACAAGGGCG
TGGTATCGAAGATCGTTCCGATCGAAGACATGCCGTACATGGCCGACGGCCGTCCGGCTGACGTCGTTCTGAACCCGCTC
GGCGTGCCGTCGCGGATGAACGTGGGTCAGGTTCTCGAAGTGCATCTGGGTTGGGCCGCGAAGGGTCTCGGCTGGCGTAT
CGGCGAAATGCTGCAGCGTCAGGCCAAGATCGCTGAACTGCGCGAATTCCTGACCAAGATCTACAACGAGTCGGGCCGCG
CTGAAGAGCTGGACAGCTTCACGGACGACGAAATCGTCGAACTGGCGAAGAACCTGCGCGAAGGCGTGCCGTTCGCTACG
CCGGTGTTCGACGGCGCGACGGAAGAGGAAATGTCGCGCGCGCTGGATCTCGCATTCCCGGACGACATCGCGAAGAACCT
CGGCATGACGCCGTCGAAGAACCAGGTGCGTCTGTACGACGGCCGCACGGGCGAAATGTTCGAACGTACGGTGACGGTCG
GCTACATGCACTACCTGAAACTGCACCACCTGGTCGACGACAAGATGCACGCGCGTTCCACGGGCCCGTACTCGCTCGTG
ACGCAGCAGCCGTTGGGCGGTAAGGCGCAATTCGGTGGCCAGCGTTTCGGTGAAATGGAAGTGTGGGCGCTCGAAGCGTA
CGGCGCATCGTACGTGCTGCAGGAAATGCTGACGGTGAAGTCGGACGACGTGACAGGCCGGACCAAGGTTTATGAAAACC
TGGTCAAGGGCGATCACGTGATCGACGCCGGCATGCCGGAATCCTTCAACGTGTTGGTGAAGGAAATCCGCTCGCTCGGT
ATCGATATCGACCTCGACCGCAACTAA

Upstream 100 bases:

>100_bases
AGCCATCGGACGGCCATCGGGTCTCAGTCGGTGAACACTCGGGTTGTCTCATCAAGGTATCCTGCCTCGACAACAATGCC
CGCCGTGATTCGGAGATCGT

Downstream 100 bases:

>100_bases
TCGGACTACGGAGAGAAAGCAATGAAAGCTCTGCTCGATCTATTCAAGCAAGTCCAACAGCCTGAAGTTTTTGACGCGAT
CAAGATCGGTCTGGCTTCGC

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta [H]

Number of amino acids: Translated: 1368; Mature: 1368

Protein sequence:

>1368_residues
MQYSFTEKKRIRKSFAKRPIVHQVPFLLATQLESFSTFLQADTSSTQRKPEGLQAAFTSVFPIVSHNGFARLEFVSYMLS
PPAFNIKECQQRGLTYCSALRAKVRLVLLDKESPSKPVVKEVKEQEVYMGEIPLMTPTGSFVINGTERVIVSQLHRSPGV
FFEHDKGKTHSSGKLLFSARIIPYRGSWLDFEFDPKDVLYFRVDRRRKMPVTILLKAIGLTPEQILANFFVFDNFTLMPE
GAQMEFVPERLRGEVARFDITDRDGNVIVQKDKRINAKHIRDLDNAKTKFISVPEDYLLGRVLAKNVVDGDTGEVIANAN
DEITETVLEKLRESKIKDIQTLYTNDLDQGPYISSTLRIDETADKMAARIAIYRMMRPGEPPTEEAVEALFNRLFYSEDA
YDLSKVGRMKFNRRVGRDEIVGPMTLQDDDILATIKILVELRNGKGEVDDIDHLGNRRVRCVGELAENQFRAGLVRVERA
VKERLGQAESENLMPHDLINSKPISSAIREFFGSSQLSQFMDQTNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHPTH
YGRVCPIETPEGPNIGLINSLALYAHLNEYGFLETPYRKVVDSKVTDQIDYLSAIEEGRYVIAQANAAVAEDGSLTDELV
SSREAGETLMVTPDRIQYMDVAPSQIVSVAASLIPFLEHDDANRALMGSNMQRQAVPCLRPEKAVVGTGIERTVAVDSGT
TVQAFRGGVVDYVDAGRMVIRVNDDEAVAGDVGVDIYNLIKYTRSNQNTNINQRPIVKVGDIVSRGDVLADGASTDLGEL
ALGQNMLVAFMPWNGYNFEDSILISEKVVADDRYTSIHIEELNVVARDTKLGPEEITRDISNLAEVQLGRLDESGIVYIG
AEVEAGDVLVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPSGMSGTVIDVQVFTREGIQRDKRAQQIIDDELK
RYRLDLNDQLRIVEGDAFQRLARMLTGKVANGGPKKLAKGTKIEQAYLEDLDHYHWFDIRLADEEAAAQLEAIKDSIEQK
RHQFDLAFEEKRKKLTQGDELPPGVLKMVKVYLAVKRRLQPGDKMAGRHGNKGVVSKIVPIEDMPYMADGRPADVVLNPL
GVPSRMNVGQVLEVHLGWAAKGLGWRIGEMLQRQAKIAELREFLTKIYNESGRAEELDSFTDDEIVELAKNLREGVPFAT
PVFDGATEEEMSRALDLAFPDDIAKNLGMTPSKNQVRLYDGRTGEMFERTVTVGYMHYLKLHHLVDDKMHARSTGPYSLV
TQQPLGGKAQFGGQRFGEMEVWALEAYGASYVLQEMLTVKSDDVTGRTKVYENLVKGDHVIDAGMPESFNVLVKEIRSLG
IDIDLDRN

Sequences:

>Translated_1368_residues
MQYSFTEKKRIRKSFAKRPIVHQVPFLLATQLESFSTFLQADTSSTQRKPEGLQAAFTSVFPIVSHNGFARLEFVSYMLS
PPAFNIKECQQRGLTYCSALRAKVRLVLLDKESPSKPVVKEVKEQEVYMGEIPLMTPTGSFVINGTERVIVSQLHRSPGV
FFEHDKGKTHSSGKLLFSARIIPYRGSWLDFEFDPKDVLYFRVDRRRKMPVTILLKAIGLTPEQILANFFVFDNFTLMPE
GAQMEFVPERLRGEVARFDITDRDGNVIVQKDKRINAKHIRDLDNAKTKFISVPEDYLLGRVLAKNVVDGDTGEVIANAN
DEITETVLEKLRESKIKDIQTLYTNDLDQGPYISSTLRIDETADKMAARIAIYRMMRPGEPPTEEAVEALFNRLFYSEDA
YDLSKVGRMKFNRRVGRDEIVGPMTLQDDDILATIKILVELRNGKGEVDDIDHLGNRRVRCVGELAENQFRAGLVRVERA
VKERLGQAESENLMPHDLINSKPISSAIREFFGSSQLSQFMDQTNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHPTH
YGRVCPIETPEGPNIGLINSLALYAHLNEYGFLETPYRKVVDSKVTDQIDYLSAIEEGRYVIAQANAAVAEDGSLTDELV
SSREAGETLMVTPDRIQYMDVAPSQIVSVAASLIPFLEHDDANRALMGSNMQRQAVPCLRPEKAVVGTGIERTVAVDSGT
TVQAFRGGVVDYVDAGRMVIRVNDDEAVAGDVGVDIYNLIKYTRSNQNTNINQRPIVKVGDIVSRGDVLADGASTDLGEL
ALGQNMLVAFMPWNGYNFEDSILISEKVVADDRYTSIHIEELNVVARDTKLGPEEITRDISNLAEVQLGRLDESGIVYIG
AEVEAGDVLVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPSGMSGTVIDVQVFTREGIQRDKRAQQIIDDELK
RYRLDLNDQLRIVEGDAFQRLARMLTGKVANGGPKKLAKGTKIEQAYLEDLDHYHWFDIRLADEEAAAQLEAIKDSIEQK
RHQFDLAFEEKRKKLTQGDELPPGVLKMVKVYLAVKRRLQPGDKMAGRHGNKGVVSKIVPIEDMPYMADGRPADVVLNPL
GVPSRMNVGQVLEVHLGWAAKGLGWRIGEMLQRQAKIAELREFLTKIYNESGRAEELDSFTDDEIVELAKNLREGVPFAT
PVFDGATEEEMSRALDLAFPDDIAKNLGMTPSKNQVRLYDGRTGEMFERTVTVGYMHYLKLHHLVDDKMHARSTGPYSLV
TQQPLGGKAQFGGQRFGEMEVWALEAYGASYVLQEMLTVKSDDVTGRTKVYENLVKGDHVIDAGMPESFNVLVKEIRSLG
IDIDLDRN
>Mature_1368_residues
MQYSFTEKKRIRKSFAKRPIVHQVPFLLATQLESFSTFLQADTSSTQRKPEGLQAAFTSVFPIVSHNGFARLEFVSYMLS
PPAFNIKECQQRGLTYCSALRAKVRLVLLDKESPSKPVVKEVKEQEVYMGEIPLMTPTGSFVINGTERVIVSQLHRSPGV
FFEHDKGKTHSSGKLLFSARIIPYRGSWLDFEFDPKDVLYFRVDRRRKMPVTILLKAIGLTPEQILANFFVFDNFTLMPE
GAQMEFVPERLRGEVARFDITDRDGNVIVQKDKRINAKHIRDLDNAKTKFISVPEDYLLGRVLAKNVVDGDTGEVIANAN
DEITETVLEKLRESKIKDIQTLYTNDLDQGPYISSTLRIDETADKMAARIAIYRMMRPGEPPTEEAVEALFNRLFYSEDA
YDLSKVGRMKFNRRVGRDEIVGPMTLQDDDILATIKILVELRNGKGEVDDIDHLGNRRVRCVGELAENQFRAGLVRVERA
VKERLGQAESENLMPHDLINSKPISSAIREFFGSSQLSQFMDQTNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHPTH
YGRVCPIETPEGPNIGLINSLALYAHLNEYGFLETPYRKVVDSKVTDQIDYLSAIEEGRYVIAQANAAVAEDGSLTDELV
SSREAGETLMVTPDRIQYMDVAPSQIVSVAASLIPFLEHDDANRALMGSNMQRQAVPCLRPEKAVVGTGIERTVAVDSGT
TVQAFRGGVVDYVDAGRMVIRVNDDEAVAGDVGVDIYNLIKYTRSNQNTNINQRPIVKVGDIVSRGDVLADGASTDLGEL
ALGQNMLVAFMPWNGYNFEDSILISEKVVADDRYTSIHIEELNVVARDTKLGPEEITRDISNLAEVQLGRLDESGIVYIG
AEVEAGDVLVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPSGMSGTVIDVQVFTREGIQRDKRAQQIIDDELK
RYRLDLNDQLRIVEGDAFQRLARMLTGKVANGGPKKLAKGTKIEQAYLEDLDHYHWFDIRLADEEAAAQLEAIKDSIEQK
RHQFDLAFEEKRKKLTQGDELPPGVLKMVKVYLAVKRRLQPGDKMAGRHGNKGVVSKIVPIEDMPYMADGRPADVVLNPL
GVPSRMNVGQVLEVHLGWAAKGLGWRIGEMLQRQAKIAELREFLTKIYNESGRAEELDSFTDDEIVELAKNLREGVPFAT
PVFDGATEEEMSRALDLAFPDDIAKNLGMTPSKNQVRLYDGRTGEMFERTVTVGYMHYLKLHHLVDDKMHARSTGPYSLV
TQQPLGGKAQFGGQRFGEMEVWALEAYGASYVLQEMLTVKSDDVTGRTKVYENLVKGDHVIDAGMPESFNVLVKEIRSLG
IDIDLDRN

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family [H]

Homologues:

Organism=Homo sapiens, GI33469941, Length=329, Percent_Identity=27.6595744680851, Blast_Score=115, Evalue=3e-25,
Organism=Homo sapiens, GI212286172, Length=329, Percent_Identity=27.6595744680851, Blast_Score=115, Evalue=3e-25,
Organism=Homo sapiens, GI4505941, Length=311, Percent_Identity=27.9742765273312, Blast_Score=112, Evalue=2e-24,
Organism=Homo sapiens, GI238908503, Length=131, Percent_Identity=38.9312977099237, Blast_Score=86, Evalue=3e-16,
Organism=Homo sapiens, GI238908505, Length=131, Percent_Identity=38.9312977099237, Blast_Score=86, Evalue=3e-16,
Organism=Escherichia coli, GI1790419, Length=1369, Percent_Identity=65.6683710737765, Blast_Score=1838, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17552304, Length=256, Percent_Identity=30.46875, Blast_Score=112, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI25144348, Length=309, Percent_Identity=27.831715210356, Blast_Score=94, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17506623, Length=85, Percent_Identity=42.3529411764706, Blast_Score=75, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6324781, Length=305, Percent_Identity=31.8032786885246, Blast_Score=127, Evalue=9e-30,
Organism=Saccharomyces cerevisiae, GI6324725, Length=257, Percent_Identity=31.1284046692607, Blast_Score=121, Evalue=6e-28,
Organism=Saccharomyces cerevisiae, GI6325267, Length=85, Percent_Identity=44.7058823529412, Blast_Score=78, Evalue=9e-15,
Organism=Drosophila melanogaster, GI17647877, Length=304, Percent_Identity=29.9342105263158, Blast_Score=117, Evalue=6e-26,
Organism=Drosophila melanogaster, GI17136444, Length=256, Percent_Identity=29.296875, Blast_Score=105, Evalue=2e-22,
Organism=Drosophila melanogaster, GI17136446, Length=86, Percent_Identity=44.1860465116279, Blast_Score=72, Evalue=3e-12,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724 [H]

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 153058; Mature: 153058

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYSFTEKKRIRKSFAKRPIVHQVPFLLATQLESFSTFLQADTSSTQRKPEGLQAAFTSV
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
FPIVSHNGFARLEFVSYMLSPPAFNIKECQQRGLTYCSALRAKVRLVLLDKESPSKPVVK
HHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHHEEEEEEEECCCCCCHHHH
EVKEQEVYMGEIPLMTPTGSFVINGTERVIVSQLHRSPGVFFEHDKGKTHSSGKLLFSAR
HHHHHHHEECCCCEECCCCCEEECCHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEEE
IIPYRGSWLDFEFDPKDVLYFRVDRRRKMPVTILLKAIGLTPEQILANFFVFDNFTLMPE
EEEECCCEEEEEECCCCEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCEEECCC
GAQMEFVPERLRGEVARFDITDRDGNVIVQKDKRINAKHIRDLDNAKTKFISVPEDYLLG
CCCCCCCHHHHCCCEEEEEEECCCCCEEEECCCCCCHHHHHHCCCCCCEEEECCHHHHHH
RVLAKNVVDGDTGEVIANANDEITETVLEKLRESKIKDIQTLYTNDLDQGPYISSTLRID
HHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEC
ETADKMAARIAIYRMMRPGEPPTEEAVEALFNRLFYSEDAYDLSKVGRMKFNRRVGRDEI
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHC
VGPMTLQDDDILATIKILVELRNGKGEVDDIDHLGNRRVRCVGELAENQFRAGLVRVERA
CCCCEECCCHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
VKERLGQAESENLMPHDLINSKPISSAIREFFGSSQLSQFMDQTNPLSEITHKRRVSALG
HHHHHCCCCCCCCCCHHHCCCCCHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHCCC
PGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLALYAHLNEYGFLETPYRKV
CCCCCHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHH
VDSKVTDQIDYLSAIEEGRYVIAQANAAVAEDGSLTDELVSSREAGETLMVTPDRIQYMD
HHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCEEEECCCCEEEEE
VAPSQIVSVAASLIPFLEHDDANRALMGSNMQRQAVPCLRPEKAVVGTGIERTVAVDSGT
CCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHCCCCCCCCCHHCCCCCCEEEEECCCC
TVQAFRGGVVDYVDAGRMVIRVNDDEAVAGDVGVDIYNLIKYTRSNQNTNINQRPIVKVG
CHHHHHCCCEEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEECC
DIVSRGDVLADGASTDLGELALGQNMLVAFMPWNGYNFEDSILISEKVVADDRYTSIHIE
CHHHCCCEEECCCCCCHHHHHCCCCEEEEEECCCCCCCCCCEEEEHHHCCCCCEEEEEEE
ELNVVARDTKLGPEEITRDISNLAEVQLGRLDESGIVYIGAEVEAGDVLVGKVTPKGETQ
HHEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECEECCCCEEEEECCCCCCCC
LTPEEKLLRAIFGEKASDVKDTSLRVPSGMSGTVIDVQVFTREGIQRDKRAQQIIDDELK
CCHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHH
RYRLDLNDQLRIVEGDAFQRLARMLTGKVANGGPKKLAKGTKIEQAYLEDLDHYHWFDIR
HHCCCCCCCEEEEECHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHCCCCEEEEEE
LADEEAAAQLEAIKDSIEQKRHQFDLAFEEKRKKLTQGDELPPGVLKMVKVYLAVKRRLQ
ECCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCC
PGDKMAGRHGNKGVVSKIVPIEDMPYMADGRPADVVLNPLGVPSRMNVGQVLEVHLGWAA
CCHHHCCCCCCCCCHHEECCCCCCCCCCCCCCHHEEECCCCCCCCCCCCCEEEEEECCHH
KGLGWRIGEMLQRQAKIAELREFLTKIYNESGRAEELDSFTDDEIVELAKNLREGVPFAT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCC
PVFDGATEEEMSRALDLAFPDDIAKNLGMTPSKNQVRLYDGRTGEMFERTVTVGYMHYLK
CCCCCCCHHHHHHHHCCCCCHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
LHHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASYVLQEMLTVK
HHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHC
SDDVTGRTKVYENLVKGDHVIDAGMPESFNVLVKEIRSLGIDIDLDRN
CCCCCCHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCCEEECCC
>Mature Secondary Structure
MQYSFTEKKRIRKSFAKRPIVHQVPFLLATQLESFSTFLQADTSSTQRKPEGLQAAFTSV
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
FPIVSHNGFARLEFVSYMLSPPAFNIKECQQRGLTYCSALRAKVRLVLLDKESPSKPVVK
HHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHHEEEEEEEECCCCCCHHHH
EVKEQEVYMGEIPLMTPTGSFVINGTERVIVSQLHRSPGVFFEHDKGKTHSSGKLLFSAR
HHHHHHHEECCCCEECCCCCEEECCHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEEE
IIPYRGSWLDFEFDPKDVLYFRVDRRRKMPVTILLKAIGLTPEQILANFFVFDNFTLMPE
EEEECCCEEEEEECCCCEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCEEECCC
GAQMEFVPERLRGEVARFDITDRDGNVIVQKDKRINAKHIRDLDNAKTKFISVPEDYLLG
CCCCCCCHHHHCCCEEEEEEECCCCCEEEECCCCCCHHHHHHCCCCCCEEEECCHHHHHH
RVLAKNVVDGDTGEVIANANDEITETVLEKLRESKIKDIQTLYTNDLDQGPYISSTLRID
HHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEC
ETADKMAARIAIYRMMRPGEPPTEEAVEALFNRLFYSEDAYDLSKVGRMKFNRRVGRDEI
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHC
VGPMTLQDDDILATIKILVELRNGKGEVDDIDHLGNRRVRCVGELAENQFRAGLVRVERA
CCCCEECCCHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
VKERLGQAESENLMPHDLINSKPISSAIREFFGSSQLSQFMDQTNPLSEITHKRRVSALG
HHHHHCCCCCCCCCCHHHCCCCCHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHCCC
PGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLALYAHLNEYGFLETPYRKV
CCCCCHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHH
VDSKVTDQIDYLSAIEEGRYVIAQANAAVAEDGSLTDELVSSREAGETLMVTPDRIQYMD
HHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCEEEECCCCEEEEE
VAPSQIVSVAASLIPFLEHDDANRALMGSNMQRQAVPCLRPEKAVVGTGIERTVAVDSGT
CCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHCCCCCCCCCHHCCCCCCEEEEECCCC
TVQAFRGGVVDYVDAGRMVIRVNDDEAVAGDVGVDIYNLIKYTRSNQNTNINQRPIVKVG
CHHHHHCCCEEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEECC
DIVSRGDVLADGASTDLGELALGQNMLVAFMPWNGYNFEDSILISEKVVADDRYTSIHIE
CHHHCCCEEECCCCCCHHHHHCCCCEEEEEECCCCCCCCCCEEEEHHHCCCCCEEEEEEE
ELNVVARDTKLGPEEITRDISNLAEVQLGRLDESGIVYIGAEVEAGDVLVGKVTPKGETQ
HHEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECEECCCCEEEEECCCCCCCC
LTPEEKLLRAIFGEKASDVKDTSLRVPSGMSGTVIDVQVFTREGIQRDKRAQQIIDDELK
CCHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHH
RYRLDLNDQLRIVEGDAFQRLARMLTGKVANGGPKKLAKGTKIEQAYLEDLDHYHWFDIR
HHCCCCCCCEEEEECHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHCCCCEEEEEE
LADEEAAAQLEAIKDSIEQKRHQFDLAFEEKRKKLTQGDELPPGVLKMVKVYLAVKRRLQ
ECCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCC
PGDKMAGRHGNKGVVSKIVPIEDMPYMADGRPADVVLNPLGVPSRMNVGQVLEVHLGWAA
CCHHHCCCCCCCCCHHEECCCCCCCCCCCCCCHHEEECCCCCCCCCCCCCEEEEEECCHH
KGLGWRIGEMLQRQAKIAELREFLTKIYNESGRAEELDSFTDDEIVELAKNLREGVPFAT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCC
PVFDGATEEEMSRALDLAFPDDIAKNLGMTPSKNQVRLYDGRTGEMFERTVTVGYMHYLK
CCCCCCCHHHHHHHHCCCCCHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
LHHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASYVLQEMLTVK
HHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHC
SDDVTGRTKVYENLVKGDHVIDAGMPESFNVLVKEIRSLGIDIDLDRN
CCCCCCHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA