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The map label for this gene is hisE

Identifier: 91785373

GI number: 91785373

Start: 4432522

End: 4432917

Strand: Reverse

Name: hisE

Synonym: Bxe_A0406

Alternate gene names: 91785373

Gene position: 4432917-4432522 (Counterclockwise)

Preceding gene: 91785374

Following gene: 91785372

Centisome position: 90.54

GC content: 65.66

Gene sequence:

>396_bases
ATGACGCAATCCACGCAAACCACGCCGTCCAACGCCGCGTCCACCACCGACACGCTGCTGCGCCTCGCGGCGATCATCGA
CAGCCGCAAGGGCGGCGATCCGGAGGTCTCGTATGTGTCGCGCCTGTTCCACAAAGGCGACGACGCGGTGCTGAAGAAGA
TCGGCGAAGAAGCCACCGAAGTCGTGCTGGCCGCCAAGGACGCACGCCACGGCGGCGCGCCGAAGGCGCTGGTCGGCGAA
GTCGCGGACTTATGGTTCCATTGCCTCGTCATGCTGTCGCACTTCGATCTGAGCCCGGCTGACGTGCTCGCCGAACTCGA
ACGCCGCGAAGGCATGTCGGGTATCGAGGAAAAGGCGCTGCGCAAGAGCCGCGACCGCGAGCAGAACGGCGACTGA

Upstream 100 bases:

>100_bases
GCCGCCACTCGTGCTTTTTCCAGAAATTCGAAGGCTCGGTGGAAGATGGCGACTGGGTTGCCGTCGACGCCGTGCTGAAA
GACCCCGAACAGATCTACAA

Downstream 100 bases:

>100_bases
GCGACGGCTGAGCGGCAACTGAGCGGAGGCCGAACGACGGACGTTCGGCGCACCGTCTTGAACTGGCGAGCAACGGCGCC
CATATTGCACTGAACGCATC

Product: phosphoribosyl-ATP pyrophosphatase

Products: NA

Alternate protein names: PRA-PH

Number of amino acids: Translated: 131; Mature: 130

Protein sequence:

>131_residues
MTQSTQTTPSNAASTTDTLLRLAAIIDSRKGGDPEVSYVSRLFHKGDDAVLKKIGEEATEVVLAAKDARHGGAPKALVGE
VADLWFHCLVMLSHFDLSPADVLAELERREGMSGIEEKALRKSRDREQNGD

Sequences:

>Translated_131_residues
MTQSTQTTPSNAASTTDTLLRLAAIIDSRKGGDPEVSYVSRLFHKGDDAVLKKIGEEATEVVLAAKDARHGGAPKALVGE
VADLWFHCLVMLSHFDLSPADVLAELERREGMSGIEEKALRKSRDREQNGD
>Mature_130_residues
TQSTQTTPSNAASTTDTLLRLAAIIDSRKGGDPEVSYVSRLFHKGDDAVLKKIGEEATEVVLAAKDARHGGAPKALVGEV
ADLWFHCLVMLSHFDLSPADVLAELERREGMSGIEEKALRKSRDREQNGD

Specific function: Histidine biosynthesis; second step. Histidine biosynthesis; third step. [C]

COG id: COG0140

COG function: function code E; Phosphoribosyl-ATP pyrophosphohydrolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PRA-PH family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HIS2_BURXL (Q13TR2)

Other databases:

- EMBL:   CP000270
- RefSeq:   YP_560579.1
- ProteinModelPortal:   Q13TR2
- SMR:   Q13TR2
- GeneID:   4006012
- GenomeReviews:   CP000270_GR
- KEGG:   bxe:Bxe_A0406
- HOGENOM:   HBG646527
- OMA:   ETVMAAK
- ProtClustDB:   PRK00400
- GO:   GO:0005737
- HAMAP:   MF_01020
- InterPro:   IPR008179
- InterPro:   IPR021130
- TIGRFAMs:   TIGR03188

Pfam domain/function: PF01503 PRA-PH

EC number: =3.6.1.31

Molecular weight: Translated: 14218; Mature: 14087

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQSTQTTPSNAASTTDTLLRLAAIIDSRKGGDPEVSYVSRLFHKGDDAVLKKIGEEATE
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHH
VVLAAKDARHGGAPKALVGEVADLWFHCLVMLSHFDLSPADVLAELERREGMSGIEEKAL
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHH
RKSRDREQNGD
HHHHHHCCCCC
>Mature Secondary Structure 
TQSTQTTPSNAASTTDTLLRLAAIIDSRKGGDPEVSYVSRLFHKGDDAVLKKIGEEATE
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHH
VVLAAKDARHGGAPKALVGEVADLWFHCLVMLSHFDLSPADVLAELERREGMSGIEEKAL
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHH
RKSRDREQNGD
HHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA