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The map label for this gene is murC [H]

Identifier: 91785292

GI number: 91785292

Start: 4340439

End: 4341842

Strand: Reverse

Name: murC [H]

Synonym: Bxe_A0487

Alternate gene names: 91785292

Gene position: 4341842-4340439 (Counterclockwise)

Preceding gene: 91785293

Following gene: 91785291

Centisome position: 88.68

GC content: 64.39

Gene sequence:

>1404_bases
ATGAAACACATCGTCAAACACATTCACTTTGTCGGCATCGGCGGTGTCGGCATGAGCGGCATCGCGGAGGTGCTGGTCAA
CCTCGGCTATCAGGTGAGCGGCTCGGATCTGACGAGCAACGCGATTACCGATCGCCTCGCCGCACTCGGCGCGCGCATCG
CGATCGGTCACGCTGCGGAGAACATTGAAGGCGCGAACGCGGTAGTCGTTTCTACCGCGGTGCGTAGTGACAATCCGGAA
GTGCTGGCCGCGCGCCATCGCCGCATTCCGATCGTGCCGCGTGCGGTGATGCTCGCGGAACTGATGCGCCTGAAGCAGGG
CATTGCAATTGCCGGCACGCACGGCAAGACCACGACCACCTCGCTGGTGGCGAGCGTGCTCGCCGCCGGTGGACTCGACC
CGACCTTCGTGATCGGCGGCCGGCTGATCAGCGCGGGCGCGAATGCGCGGCTCGGTACGGGCGACTTCATCGTCGCGGAA
GCCGACGAGTCGGACGCGTCGTTCCTGAATCTGTTCCCGGTGATCGAAGTCATCACGAACATCGACGCCGATCACATGGA
CACCTACGGCCACGACTTCGCGCGGCTCAAGCAGGCGTTCATCGAATTCACGCACCGTCTGCCGTTCTACGGCATCGCGG
TGCTGTGCGTCGACGATCCGAACGTGAAGGAAATCCTGCCGTTCGTGTCGAAGCCGATCATCCGCTACGGCTTCGCGCCG
GACGCGCAGGTGCGCGCGGTGAACGTACAGGCACGCGACGGCAAGATGCATTTTACGGCGATGCGCGAAGACGCGGCGCC
GCTCGACATCGTGCTGAACCTGCCGGGCGAGCACAACGTGCAGAACGCTTTGGCCGCCATTGCCATTGCGACTGAACTTG
AAGTGAAAGATGCCGATATCCAGCGAGCGCTGGCGGATTTCAACGGCGTGGGCCGACGCTTCCAGCGCTACGGCGAGGTG
CCGGTGTTCAGCGAAGGCAGCACGAACGGCGCGTACACACTGGTCGACGACTACGGTCATCACCCGGTCGAAATGGCGGC
CACGGTGGCGGCGGCGCGCGGCGCATTTCCGGGCCGGCGTCTGGTGCTGGCATTCCAGCCGCACCGCTTCACGCGTACGC
GTGACTGCTTCGAAGATTTTGTGAAAGTGCTGTCGACCGTCGACGCGTTGGTGCTGACCGAAGTCTATTCGGCCGGCGAG
TCGCCGATCGTCGCCGCGGACGGCCGCGCTCTCGCGCGTGCGCTGCGGGTGGCAGGCAAGGTCGAACCGGTGTTTGTCGA
TACGGTGGATGAAGTGCCGGACGCGCTCTCGGCGATAGTGCGCGACGGCGATGTGGTGATCACGATGGGCGCAGGTTCGA
TCGGCGGTGTGCCGGCTCGCCTCGCGCAGGAAACAAAGGTGTGA

Upstream 100 bases:

>100_bases
GTTCGCGCTCGCTCGCGAAACCCGACGCCACGGAACAGGTCGCGCAGATTTGCGCGACCGTGGCGGGTTCGATTTCGGGC
GCGAGCCCAGAAGGAAAGCA

Downstream 100 bases:

>100_bases
GTGAGATGAGCAGTATCGACCCCAAACAGTTCGGCAAGGTGGCAGTGCTGCTCGGCGGTAATTCCGCCGAGCGCGAGGTG
TCGCTCAATTCCGGGCGTCT

Product: UDP-N-acetylmuramate--L-alanine ligase

Products: NA

Alternate protein names: UDP-N-acetylmuramoyl-L-alanine synthetase [H]

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MKHIVKHIHFVGIGGVGMSGIAEVLVNLGYQVSGSDLTSNAITDRLAALGARIAIGHAAENIEGANAVVVSTAVRSDNPE
VLAARHRRIPIVPRAVMLAELMRLKQGIAIAGTHGKTTTTSLVASVLAAGGLDPTFVIGGRLISAGANARLGTGDFIVAE
ADESDASFLNLFPVIEVITNIDADHMDTYGHDFARLKQAFIEFTHRLPFYGIAVLCVDDPNVKEILPFVSKPIIRYGFAP
DAQVRAVNVQARDGKMHFTAMREDAAPLDIVLNLPGEHNVQNALAAIAIATELEVKDADIQRALADFNGVGRRFQRYGEV
PVFSEGSTNGAYTLVDDYGHHPVEMAATVAAARGAFPGRRLVLAFQPHRFTRTRDCFEDFVKVLSTVDALVLTEVYSAGE
SPIVAADGRALARALRVAGKVEPVFVDTVDEVPDALSAIVRDGDVVITMGAGSIGGVPARLAQETKV

Sequences:

>Translated_467_residues
MKHIVKHIHFVGIGGVGMSGIAEVLVNLGYQVSGSDLTSNAITDRLAALGARIAIGHAAENIEGANAVVVSTAVRSDNPE
VLAARHRRIPIVPRAVMLAELMRLKQGIAIAGTHGKTTTTSLVASVLAAGGLDPTFVIGGRLISAGANARLGTGDFIVAE
ADESDASFLNLFPVIEVITNIDADHMDTYGHDFARLKQAFIEFTHRLPFYGIAVLCVDDPNVKEILPFVSKPIIRYGFAP
DAQVRAVNVQARDGKMHFTAMREDAAPLDIVLNLPGEHNVQNALAAIAIATELEVKDADIQRALADFNGVGRRFQRYGEV
PVFSEGSTNGAYTLVDDYGHHPVEMAATVAAARGAFPGRRLVLAFQPHRFTRTRDCFEDFVKVLSTVDALVLTEVYSAGE
SPIVAADGRALARALRVAGKVEPVFVDTVDEVPDALSAIVRDGDVVITMGAGSIGGVPARLAQETKV
>Mature_467_residues
MKHIVKHIHFVGIGGVGMSGIAEVLVNLGYQVSGSDLTSNAITDRLAALGARIAIGHAAENIEGANAVVVSTAVRSDNPE
VLAARHRRIPIVPRAVMLAELMRLKQGIAIAGTHGKTTTTSLVASVLAAGGLDPTFVIGGRLISAGANARLGTGDFIVAE
ADESDASFLNLFPVIEVITNIDADHMDTYGHDFARLKQAFIEFTHRLPFYGIAVLCVDDPNVKEILPFVSKPIIRYGFAP
DAQVRAVNVQARDGKMHFTAMREDAAPLDIVLNLPGEHNVQNALAAIAIATELEVKDADIQRALADFNGVGRRFQRYGEV
PVFSEGSTNGAYTLVDDYGHHPVEMAATVAAARGAFPGRRLVLAFQPHRFTRTRDCFEDFVKVLSTVDALVLTEVYSAGE
SPIVAADGRALARALRVAGKVEPVFVDTVDEVPDALSAIVRDGDVVITMGAGSIGGVPARLAQETKV

Specific function: Cell wall formation [H]

COG id: COG0773

COG function: function code M; UDP-N-acetylmuramate-alanine ligase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MurCDEF family [H]

Homologues:

Organism=Escherichia coli, GI1786279, Length=459, Percent_Identity=54.2483660130719, Blast_Score=461, Evalue=1e-131,
Organism=Escherichia coli, GI1790680, Length=470, Percent_Identity=28.5106382978723, Blast_Score=157, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004101
- InterPro:   IPR013221
- InterPro:   IPR000713
- InterPro:   IPR016040
- InterPro:   IPR005758 [H]

Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]

EC number: =6.3.2.8 [H]

Molecular weight: Translated: 49622; Mature: 49622

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHIVKHIHFVGIGGVGMSGIAEVLVNLGYQVSGSDLTSNAITDRLAALGARIAIGHAAE
CCHHHHHHHEEEECCCCHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHEEECCHHC
NIEGANAVVVSTAVRSDNPEVLAARHRRIPIVPRAVMLAELMRLKQGIAIAGTHGKTTTT
CCCCCCEEEEEEEECCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHH
SLVASVLAAGGLDPTFVIGGRLISAGANARLGTGDFIVAEADESDASFLNLFPVIEVITN
HHHHHHHHHCCCCCEEEECCEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHC
IDADHMDTYGHDFARLKQAFIEFTHRLPFYGIAVLCVDDPNVKEILPFVSKPIIRYGFAP
CCCHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHCCHHHCCCCC
DAQVRAVNVQARDGKMHFTAMREDAAPLDIVLNLPGEHNVQNALAAIAIATELEVKDADI
CCEEEEEEEEECCCCEEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCEECHHHH
QRALADFNGVGRRFQRYGEVPVFSEGSTNGAYTLVDDYGHHPVEMAATVAAARGAFPGRR
HHHHHHHHHHHHHHHHHCCCCEECCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCE
LVLAFQPHRFTRTRDCFEDFVKVLSTVDALVLTEVYSAGESPIVAADGRALARALRVAGK
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHCC
VEPVFVDTVDEVPDALSAIVRDGDVVITMGAGSIGGVPARLAQETKV
CCEEEECCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHCCC
>Mature Secondary Structure
MKHIVKHIHFVGIGGVGMSGIAEVLVNLGYQVSGSDLTSNAITDRLAALGARIAIGHAAE
CCHHHHHHHEEEECCCCHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHEEECCHHC
NIEGANAVVVSTAVRSDNPEVLAARHRRIPIVPRAVMLAELMRLKQGIAIAGTHGKTTTT
CCCCCCEEEEEEEECCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHH
SLVASVLAAGGLDPTFVIGGRLISAGANARLGTGDFIVAEADESDASFLNLFPVIEVITN
HHHHHHHHHCCCCCEEEECCEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHC
IDADHMDTYGHDFARLKQAFIEFTHRLPFYGIAVLCVDDPNVKEILPFVSKPIIRYGFAP
CCCHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHCCHHHCCCCC
DAQVRAVNVQARDGKMHFTAMREDAAPLDIVLNLPGEHNVQNALAAIAIATELEVKDADI
CCEEEEEEEEECCCCEEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCEECHHHH
QRALADFNGVGRRFQRYGEVPVFSEGSTNGAYTLVDDYGHHPVEMAATVAAARGAFPGRR
HHHHHHHHHHHHHHHHHCCCCEECCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCE
LVLAFQPHRFTRTRDCFEDFVKVLSTVDALVLTEVYSAGESPIVAADGRALARALRVAGK
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHCC
VEPVFVDTVDEVPDALSAIVRDGDVVITMGAGSIGGVPARLAQETKV
CCEEEECCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA