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The map label for this gene is gltK [H]

Identifier: 91785180

GI number: 91785180

Start: 4214171

End: 4214848

Strand: Reverse

Name: gltK [H]

Synonym: Bxe_A0599

Alternate gene names: 91785180

Gene position: 4214848-4214171 (Counterclockwise)

Preceding gene: 91785181

Following gene: 91785179

Centisome position: 86.09

GC content: 59.88

Gene sequence:

>678_bases
ATGCACCATTTCGACTGGAGCGGTATTCCGGGCGCATTGCCTACGCTGTGGACCGGCGCCGTAGTCACTCTCAAGATCAC
GCTGATCGCGATCGTGTTCGGCATTATCTGGGGCACCGTTCTCGCGATGTTGCGGCTGTCGTCGTTCAAACCGTTCGAGT
GGTTCGCGAAGGGCTACGTGACGATCTTCCGTTCCATCCCGCTGGTGATGGTGCTGCTGTGGTTCTTCCTGATCGTGCCG
CAAGTGCTGCAGAACGTGCTCGGCCTGTCGGCGGATATCGACATTCGTCTTGCGTCGGCCATGGTCGCGTTCTCGCTGTT
CGAGGCCGCGTACTATTCGGAGATCATCCGCGCCGGCATTCAGGCCGTGCCGCGCGGACAGGTCAACGCGGCGTTCGCGC
TCGGCATGAACTACGCGCAGGCCATGCGCCTGATCGTGCTGCCGCAGGCATTCCGCGCGATGGTGCCGCTGCTGCTCACG
CAGGGTATCGTGCTGTTTCAGGATACGTCGCTCGTCTACGTAATCAGCCTCGCCGACTTCTTCCGCACCGCTACGAATAT
TGGCGACCGTGACGGTACGAATATCGAGATGGTACTGTTCGCGGGCGCGTGTTATTTCGTGGTCTGCGTGATCGCGTCGA
GCCTCGTCAAAGGTCTTCAGAAAAAGGTCGCAAGATGA

Upstream 100 bases:

>100_bases
CGGTCACGGTGGCGTACATGCTGATCAATCTGGTCGTGATGCAACTCATGCGCTGGGTCGAAGCGAAGACCCGGTTGCCC
GGCTATATCGGAGGCAAGTA

Downstream 100 bases:

>100_bases
TCTCTATCAAGAATGTTTCGAAGTGGTACGGTCAGTTTCAGGTGCTGACCGACTGCACGACGGAAGTCAAAAAAGGTGAA
GTGGTGGTGGTGTGCGGGCC

Product: His/Glu/Gln/Arg/opine ABC transporter inner membrane protein

Products: ADP; phosphate; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MHHFDWSGIPGALPTLWTGAVVTLKITLIAIVFGIIWGTVLAMLRLSSFKPFEWFAKGYVTIFRSIPLVMVLLWFFLIVP
QVLQNVLGLSADIDIRLASAMVAFSLFEAAYYSEIIRAGIQAVPRGQVNAAFALGMNYAQAMRLIVLPQAFRAMVPLLLT
QGIVLFQDTSLVYVISLADFFRTATNIGDRDGTNIEMVLFAGACYFVVCVIASSLVKGLQKKVAR

Sequences:

>Translated_225_residues
MHHFDWSGIPGALPTLWTGAVVTLKITLIAIVFGIIWGTVLAMLRLSSFKPFEWFAKGYVTIFRSIPLVMVLLWFFLIVP
QVLQNVLGLSADIDIRLASAMVAFSLFEAAYYSEIIRAGIQAVPRGQVNAAFALGMNYAQAMRLIVLPQAFRAMVPLLLT
QGIVLFQDTSLVYVISLADFFRTATNIGDRDGTNIEMVLFAGACYFVVCVIASSLVKGLQKKVAR
>Mature_225_residues
MHHFDWSGIPGALPTLWTGAVVTLKITLIAIVFGIIWGTVLAMLRLSSFKPFEWFAKGYVTIFRSIPLVMVLLWFFLIVP
QVLQNVLGLSADIDIRLASAMVAFSLFEAAYYSEIIRAGIQAVPRGQVNAAFALGMNYAQAMRLIVLPQAFRAMVPLLLT
QGIVLFQDTSLVYVISLADFFRTATNIGDRDGTNIEMVLFAGACYFVVCVIASSLVKGLQKKVAR

Specific function: Part of the binding-protein-dependent transport system for aspartate/glutamate; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786873, Length=224, Percent_Identity=70.9821428571429, Blast_Score=323, Evalue=8e-90,
Organism=Escherichia coli, GI1788226, Length=214, Percent_Identity=35.5140186915888, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI87082239, Length=209, Percent_Identity=33.9712918660287, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1786874, Length=179, Percent_Identity=30.7262569832402, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1787087, Length=227, Percent_Identity=26.8722466960352, Blast_Score=86, Evalue=1e-18,
Organism=Escherichia coli, GI1787030, Length=221, Percent_Identity=26.2443438914027, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1788645, Length=217, Percent_Identity=26.7281105990783, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1788646, Length=208, Percent_Identity=26.4423076923077, Blast_Score=77, Evalue=6e-16,
Organism=Escherichia coli, GI48994930, Length=130, Percent_Identity=32.3076923076923, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787086, Length=214, Percent_Identity=25.2336448598131, Blast_Score=68, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24786; Mature: 24786

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHHFDWSGIPGALPTLWTGAVVTLKITLIAIVFGIIWGTVLAMLRLSSFKPFEWFAKGYV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
TIFRSIPLVMVLLWFFLIVPQVLQNVLGLSADIDIRLASAMVAFSLFEAAYYSEIIRAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAVPRGQVNAAFALGMNYAQAMRLIVLPQAFRAMVPLLLTQGIVLFQDTSLVYVISLADF
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHH
FRTATNIGDRDGTNIEMVLFAGACYFVVCVIASSLVKGLQKKVAR
HHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHHFDWSGIPGALPTLWTGAVVTLKITLIAIVFGIIWGTVLAMLRLSSFKPFEWFAKGYV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
TIFRSIPLVMVLLWFFLIVPQVLQNVLGLSADIDIRLASAMVAFSLFEAAYYSEIIRAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAVPRGQVNAAFALGMNYAQAMRLIVLPQAFRAMVPLLLTQGIVLFQDTSLVYVISLADF
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHH
FRTATNIGDRDGTNIEMVLFAGACYFVVCVIASSLVKGLQKKVAR
HHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamate [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamate [Periplasm] + H2O = ADP + phosphate + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]