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The map label for this gene is lrp [H]

Identifier: 91785044

GI number: 91785044

Start: 4065723

End: 4066238

Strand: Reverse

Name: lrp [H]

Synonym: Bxe_A0736

Alternate gene names: 91785044

Gene position: 4066238-4065723 (Counterclockwise)

Preceding gene: 91785048

Following gene: 91785042

Centisome position: 83.06

GC content: 60.66

Gene sequence:

>516_bases
ATGAACGCGATCTCGCTCGACGCCACCGATTGCCGTATCTTGACGGTGCTTCAGCAAGAAGGACGGATCAGCAATCTCGA
CCTCGCGGAGCGTATCTCGCTCTCGCCGTCAGCCTGTCTGCGACGCCTGCGCCTGCTCGAAGAGCAGGGTGTCATCGAAC
ATTACCGCGCGTGTCTGAACCGCGAAGTGCTGGGATTCGAGCTGGAAGCGTTCGTGCAGGTGTCCATGCGCAACGACCAG
GAGAACTGGCACGAGCGCTTTGCGGACGCGGTGCGCGACTGGCCGGAAGTGGTCGGCGCGTTCGTCGTGACCGGCGAGAC
ACACTATCTGCTGCGCGTTCTCGCGCACAACCTCAAGCACTATTCGGATTTCGTGCTGCAGCGGCTCTACAAGGCGCCGG
GCGTGATGGATATCCGTTCGAATATCGTGCTGCAGACACTCAAGGAAGATTCGGGCGTGCCCGTTTCGTTAGTGAAGAAA
GCTAGCGGCCACGGCGCCGCGCACAACGATCGTTGA

Upstream 100 bases:

>100_bases
AATGATAGGTGGCTTGACGCGAAATGTGATTGCGAAAAAATCTCCTTCCAGGCCGTGTCTTGGAACATAATTTGAGATAA
ATGGGAAAGGGAGACCGAAT

Downstream 100 bases:

>100_bases
CGGCGCCGAAGGCCGCGCGTTCACAGCGGCTTGAGTCCGTGAAACTGGCCGTTCTGAAACACCAGGGGCGAGACTCCGGC
GGCATTTTCGTGCACGCCGC

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MNAISLDATDCRILTVLQQEGRISNLDLAERISLSPSACLRRLRLLEEQGVIEHYRACLNREVLGFELEAFVQVSMRNDQ
ENWHERFADAVRDWPEVVGAFVVTGETHYLLRVLAHNLKHYSDFVLQRLYKAPGVMDIRSNIVLQTLKEDSGVPVSLVKK
ASGHGAAHNDR

Sequences:

>Translated_171_residues
MNAISLDATDCRILTVLQQEGRISNLDLAERISLSPSACLRRLRLLEEQGVIEHYRACLNREVLGFELEAFVQVSMRNDQ
ENWHERFADAVRDWPEVVGAFVVTGETHYLLRVLAHNLKHYSDFVLQRLYKAPGVMDIRSNIVLQTLKEDSGVPVSLVKK
ASGHGAAHNDR
>Mature_171_residues
MNAISLDATDCRILTVLQQEGRISNLDLAERISLSPSACLRRLRLLEEQGVIEHYRACLNREVLGFELEAFVQVSMRNDQ
ENWHERFADAVRDWPEVVGAFVVTGETHYLLRVLAHNLKHYSDFVLQRLYKAPGVMDIRSNIVLQTLKEDSGVPVSLVKK
ASGHGAAHNDR

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=146, Percent_Identity=36.3013698630137, Blast_Score=102, Evalue=9e-24,
Organism=Escherichia coli, GI87081742, Length=150, Percent_Identity=32.6666666666667, Blast_Score=100, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 19392; Mature: 19392

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAISLDATDCRILTVLQQEGRISNLDLAERISLSPSACLRRLRLLEEQGVIEHYRACLN
CCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHC
REVLGFELEAFVQVSMRNDQENWHERFADAVRDWPEVVGAFVVTGETHYLLRVLAHNLKH
CCHHCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
YSDFVLQRLYKAPGVMDIRSNIVLQTLKEDSGVPVSLVKKASGHGAAHNDR
HHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MNAISLDATDCRILTVLQQEGRISNLDLAERISLSPSACLRRLRLLEEQGVIEHYRACLN
CCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHC
REVLGFELEAFVQVSMRNDQENWHERFADAVRDWPEVVGAFVVTGETHYLLRVLAHNLKH
CCHHCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
YSDFVLQRLYKAPGVMDIRSNIVLQTLKEDSGVPVSLVKKASGHGAAHNDR
HHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11157937; 11481430 [H]