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The map label for this gene is yeaE [H]

Identifier: 91784996

GI number: 91784996

Start: 4013375

End: 4014220

Strand: Reverse

Name: yeaE [H]

Synonym: Bxe_A0784

Alternate gene names: 91784996

Gene position: 4014220-4013375 (Counterclockwise)

Preceding gene: 91784998

Following gene: 91784983

Centisome position: 81.99

GC content: 66.08

Gene sequence:

>846_bases
ATGACGAGCGACATCGCAAGCGTGAGCCTGCCCGACGGCGAACGCATTCCGAAACTGGGACAGGGCACCTGGGAGATGGG
TGAGGTGCCGGCGCGGCGTGCCGCTGAGATCGACGCGCTGCGTTGCGGCATCGAACTCGGCATGACGTTGATCGACACGG
CGGAAATGTATGGCGACGGCGCGACCGAATCTCTGCTGGGCGTTGCGCTGGCCGGGTTGCGCGACAAGGTGTTTCTGGTC
AGCAAGGTGTATCCGCATAACGCCAGCCGGCGCGGCGTGATCGCGGCCTGCGAGCAGAGCCTCAAGCGTCTGAAGACGGA
TCAGCTCGATCTGTATCTGCTGCACTGGCGCGGCTCGGTGCCGCTCGCGGAAACGGTCGAGGGCTTCGAGGCGTTACGGC
GGGCGGGCAAGATTCGCCACTGGGGCGTCAGCAACTTCGACACCGCGGACATGGAAGAACTCGTCGCCACGCCGGGCGGC
GATGCGTGCGCAACCAATCAGATTCTCTACAACGTGGCGCGCCGCGGGCCGGAATTCGAACTGCTGCCGTGGCTCGCCGC
GCGCAAGATGCCGGCTATGGCGTACAGCCCGGTCGATCACGCACGCTTGCCGAAACGCTCGCCGCTCGACAATATCGCCG
ACGCGCGCGGCGTCTCGGTGTTCCAGGTGGCGCTCGCATGGGTGCTGCTCGCGCCCGGCGTGTTCGCGATTCCGAAGGCG
GGGCGCGCCGAGCATGTGCGCGACAACCATCGCGCGGCGCAACTGCAACTCGGCGCGGATGAACTGGCTGCCATCGACGC
GTATTTCAAACCGCCGCGCAGCAAGCGTCCGCTCGAAATGCTGTAA

Upstream 100 bases:

>100_bases
CGTTGAACCGCTAAACTCGTCGCTATGTTTTCGTGGCATACGCCGCGCATTCGCCTGCGCTGAGGCATTGCCGACCATTG
AGCCACTTCGAGGAGTCAGC

Downstream 100 bases:

>100_bases
GCGCGGCGGCGCCCGTTTGCCGCGCGACGGACGGTTCGCCGCGGGCGGCGGCTTATCGATGGCGTCGCACGCGCAATGGC
CGCGGCGGGCGCCTGATCAA

Product: aldo/keto reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MTSDIASVSLPDGERIPKLGQGTWEMGEVPARRAAEIDALRCGIELGMTLIDTAEMYGDGATESLLGVALAGLRDKVFLV
SKVYPHNASRRGVIAACEQSLKRLKTDQLDLYLLHWRGSVPLAETVEGFEALRRAGKIRHWGVSNFDTADMEELVATPGG
DACATNQILYNVARRGPEFELLPWLAARKMPAMAYSPVDHARLPKRSPLDNIADARGVSVFQVALAWVLLAPGVFAIPKA
GRAEHVRDNHRAAQLQLGADELAAIDAYFKPPRSKRPLEML

Sequences:

>Translated_281_residues
MTSDIASVSLPDGERIPKLGQGTWEMGEVPARRAAEIDALRCGIELGMTLIDTAEMYGDGATESLLGVALAGLRDKVFLV
SKVYPHNASRRGVIAACEQSLKRLKTDQLDLYLLHWRGSVPLAETVEGFEALRRAGKIRHWGVSNFDTADMEELVATPGG
DACATNQILYNVARRGPEFELLPWLAARKMPAMAYSPVDHARLPKRSPLDNIADARGVSVFQVALAWVLLAPGVFAIPKA
GRAEHVRDNHRAAQLQLGADELAAIDAYFKPPRSKRPLEML
>Mature_280_residues
TSDIASVSLPDGERIPKLGQGTWEMGEVPARRAAEIDALRCGIELGMTLIDTAEMYGDGATESLLGVALAGLRDKVFLVS
KVYPHNASRRGVIAACEQSLKRLKTDQLDLYLLHWRGSVPLAETVEGFEALRRAGKIRHWGVSNFDTADMEELVATPGGD
ACATNQILYNVARRGPEFELLPWLAARKMPAMAYSPVDHARLPKRSPLDNIADARGVSVFQVALAWVLLAPGVFAIPKAG
RAEHVRDNHRAAQLQLGADELAAIDAYFKPPRSKRPLEML

Specific function: Unknown

COG id: COG0656

COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI310109922, Length=287, Percent_Identity=29.2682926829268, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI5453543, Length=307, Percent_Identity=28.3387622149837, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI45446745, Length=307, Percent_Identity=28.3387622149837, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI4503285, Length=307, Percent_Identity=28.3387622149837, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI310109920, Length=307, Percent_Identity=28.3387622149837, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI24497583, Length=307, Percent_Identity=28.0130293159609, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI24497585, Length=305, Percent_Identity=26.8852459016393, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI223468663, Length=300, Percent_Identity=25.6666666666667, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI24497577, Length=310, Percent_Identity=24.5161290322581, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI5174391, Length=310, Percent_Identity=24.5161290322581, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI207028673, Length=127, Percent_Identity=36.2204724409449, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI310109926, Length=127, Percent_Identity=36.2204724409449, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI223718702, Length=168, Percent_Identity=30.952380952381, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI41327764, Length=165, Percent_Identity=32.7272727272727, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1788081, Length=271, Percent_Identity=53.5055350553505, Blast_Score=291, Evalue=3e-80,
Organism=Escherichia coli, GI1786400, Length=267, Percent_Identity=29.9625468164794, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI87081735, Length=297, Percent_Identity=25.9259259259259, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI87082198, Length=267, Percent_Identity=27.7153558052434, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI48994888, Length=273, Percent_Identity=29.6703296703297, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788070, Length=300, Percent_Identity=27.6666666666667, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787674, Length=258, Percent_Identity=26.7441860465116, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789199, Length=172, Percent_Identity=34.8837209302326, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17552492, Length=272, Percent_Identity=27.9411764705882, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17561298, Length=287, Percent_Identity=28.9198606271777, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71998625, Length=286, Percent_Identity=24.4755244755245, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17538386, Length=283, Percent_Identity=27.5618374558304, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17566692, Length=168, Percent_Identity=30.3571428571429, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17550248, Length=173, Percent_Identity=27.7456647398844, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324694, Length=303, Percent_Identity=27.3927392739274, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24657054, Length=307, Percent_Identity=25.7328990228013, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI45553081, Length=301, Percent_Identity=26.2458471760797, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24644950, Length=309, Percent_Identity=26.8608414239482, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21356425, Length=313, Percent_Identity=24.6006389776358, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24662789, Length=311, Percent_Identity=25.08038585209, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI20129731, Length=308, Percent_Identity=24.6753246753247, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 30689; Mature: 30557

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSDIASVSLPDGERIPKLGQGTWEMGEVPARRAAEIDALRCGIELGMTLIDTAEMYGDG
CCCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHCCC
ATESLLGVALAGLRDKVFLVSKVYPHNASRRGVIAACEQSLKRLKTDQLDLYLLHWRGSV
CHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCC
PLAETVEGFEALRRAGKIRHWGVSNFDTADMEELVATPGGDACATNQILYNVARRGPEFE
CHHHHHHHHHHHHHHCCEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCC
LLPWLAARKMPAMAYSPVDHARLPKRSPLDNIADARGVSVFQVALAWVLLAPGVFAIPKA
HHHHHHHHCCCCHHCCCCHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHCCCCEECCCC
GRAEHVRDNHRAAQLQLGADELAAIDAYFKPPRSKRPLEML
CCHHHHHHCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TSDIASVSLPDGERIPKLGQGTWEMGEVPARRAAEIDALRCGIELGMTLIDTAEMYGDG
CCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHCCC
ATESLLGVALAGLRDKVFLVSKVYPHNASRRGVIAACEQSLKRLKTDQLDLYLLHWRGSV
CHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCC
PLAETVEGFEALRRAGKIRHWGVSNFDTADMEELVATPGGDACATNQILYNVARRGPEFE
CHHHHHHHHHHHHHHCCEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCC
LLPWLAARKMPAMAYSPVDHARLPKRSPLDNIADARGVSVFQVALAWVLLAPGVFAIPKA
HHHHHHHHCCCCHHCCCCHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHCCCCEECCCC
GRAEHVRDNHRAAQLQLGADELAAIDAYFKPPRSKRPLEML
CCHHHHHHCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]