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The map label for this gene is cysM [H]

Identifier: 91784803

GI number: 91784803

Start: 3792758

End: 3793660

Strand: Reverse

Name: cysM [H]

Synonym: Bxe_A0990

Alternate gene names: 91784803

Gene position: 3793660-3792758 (Counterclockwise)

Preceding gene: 91784804

Following gene: 91784801

Centisome position: 77.49

GC content: 63.46

Gene sequence:

>903_bases
ATGGCTTACAAAACGATTGAAGACACGATCGGCAATACGCCGCTCGTGCAGCTCGTCCGGCTCCCCGACGACGAGATCCG
CAGCCGCAACAACGTGATCCTTGCGAAGCTCGAGGGCAACAACCCCGCGGGTTCGGTGAAGGATCGCCCGGCGTTGTCGA
TGATCAAGAAAGCGGAAGCGCGCGGGCGCATCAAGCCCGGCGACACGCTGATCGAATCGACCAGCGGCAACACCGGCATC
GCGCTGGCTATGGCGGCCGCGATCCGTGGCTACAAGATGGTGCTGATCATGCCGGAAGATCTGTCGGTGGAACGCCGTCA
GAGCATGGCCGCATACGGTGCGCAGATCGTGCTCACGCCGGTCACGGGCGGCATGGAGTACGCACGCGATCTGGCCGAGC
AGATGCAGCGCGAAGGCAAGGGCATCATCCTCGACCAGTTTGCCAATCCCGACAATCCGGCCGCGCACGTCGAAGGCACG
GGGCCGGAAATCTGGCGCGATACCGAAGGGCGCATTACCCACTTCGTGTCGTCGATGGGCACGACCGGCACGATCATGGG
CGTGTCCACCTATCTGAAAGAACAGAACCAGGCGATCGAGATCATCGGCGCGCAGCCCGAAGAGGGTTCGCGCATTCCGG
GCATCCGCAAATGGCCGGAAGCCTATCTGCCGAAGATTTTCGATCGCAGCCGCGTGGATCGTGTGGAGAACGTGAGCCAG
GCCGCCGCCGAGGCTATGGCGCGCCGTATGGCGTCGGTGGAGGGCATCTTTGCCGGCATCTCGTCGGGCGGCGCGTGCGA
AGTGGCGCTGCGCGTCGCGCGGCAGGTCGAGAACGCGACCATCGTGTTCATCGTTTGCGATCGCGGCGACCGTTATCTGT
CCACGGGTGTGTTTCCCGCTTAA

Upstream 100 bases:

>100_bases
CCTGCATCCATGCGCACAGAAGGGCCGCGCGGCAGGTGCGGGCACGGTGGTTTAGAATCGACGGATCAAGACTTCGCGCA
CCGACAGCACCCGAACCGAT

Downstream 100 bases:

>100_bases
ACGCTCTGCGGCGTTTCTCGTCCGTCAATGAAAAAAGCGCCGATTCGCAACCGGCGCTTTTTTCATGTCCACCCGTGAGG
CGGGCTCGTCGCGCCCGCTA

Product: cysteine synthase B

Products: NA

Alternate protein names: CSase B; O-acetylserine (thiol)-lyase B; OAS-TL B; O-acetylserine sulfhydrylase B [H]

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MAYKTIEDTIGNTPLVQLVRLPDDEIRSRNNVILAKLEGNNPAGSVKDRPALSMIKKAEARGRIKPGDTLIESTSGNTGI
ALAMAAAIRGYKMVLIMPEDLSVERRQSMAAYGAQIVLTPVTGGMEYARDLAEQMQREGKGIILDQFANPDNPAAHVEGT
GPEIWRDTEGRITHFVSSMGTTGTIMGVSTYLKEQNQAIEIIGAQPEEGSRIPGIRKWPEAYLPKIFDRSRVDRVENVSQ
AAAEAMARRMASVEGIFAGISSGGACEVALRVARQVENATIVFIVCDRGDRYLSTGVFPA

Sequences:

>Translated_300_residues
MAYKTIEDTIGNTPLVQLVRLPDDEIRSRNNVILAKLEGNNPAGSVKDRPALSMIKKAEARGRIKPGDTLIESTSGNTGI
ALAMAAAIRGYKMVLIMPEDLSVERRQSMAAYGAQIVLTPVTGGMEYARDLAEQMQREGKGIILDQFANPDNPAAHVEGT
GPEIWRDTEGRITHFVSSMGTTGTIMGVSTYLKEQNQAIEIIGAQPEEGSRIPGIRKWPEAYLPKIFDRSRVDRVENVSQ
AAAEAMARRMASVEGIFAGISSGGACEVALRVARQVENATIVFIVCDRGDRYLSTGVFPA
>Mature_299_residues
AYKTIEDTIGNTPLVQLVRLPDDEIRSRNNVILAKLEGNNPAGSVKDRPALSMIKKAEARGRIKPGDTLIESTSGNTGIA
LAMAAAIRGYKMVLIMPEDLSVERRQSMAAYGAQIVLTPVTGGMEYARDLAEQMQREGKGIILDQFANPDNPAAHVEGTG
PEIWRDTEGRITHFVSSMGTTGTIMGVSTYLKEQNQAIEIIGAQPEEGSRIPGIRKWPEAYLPKIFDRSRVDRVENVSQA
AAEAMARRMASVEGIFAGISSGGACEVALRVARQVENATIVFIVCDRGDRYLSTGVFPA

Specific function: Two Cysteine Synthase Enzymes Are Found. Both Catalyze The Same Reaction. Cysteine Synthase B Can Also Use Thiosulfate In Place Of Sulfide To Give Cysteine Thiosulfonate As A Product. [C]

COG id: COG0031

COG function: function code E; Cysteine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cysteine synthase/cystathionine beta- synthase family [H]

Homologues:

Organism=Homo sapiens, GI295821202, Length=302, Percent_Identity=36.7549668874172, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI295821200, Length=302, Percent_Identity=36.7549668874172, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI4557415, Length=302, Percent_Identity=36.7549668874172, Blast_Score=174, Evalue=1e-43,
Organism=Escherichia coli, GI2367138, Length=295, Percent_Identity=62.3728813559322, Blast_Score=367, Evalue=1e-103,
Organism=Escherichia coli, GI1788754, Length=317, Percent_Identity=43.5331230283912, Blast_Score=202, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI17562970, Length=302, Percent_Identity=42.7152317880795, Blast_Score=209, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17535051, Length=305, Percent_Identity=41.3114754098361, Blast_Score=209, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI32566674, Length=297, Percent_Identity=43.4343434343434, Blast_Score=207, Evalue=5e-54,
Organism=Caenorhabditis elegans, GI115535073, Length=300, Percent_Identity=40.3333333333333, Blast_Score=194, Evalue=5e-50,
Organism=Caenorhabditis elegans, GI17561720, Length=302, Percent_Identity=40.3973509933775, Blast_Score=187, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI25147552, Length=315, Percent_Identity=33.968253968254, Blast_Score=140, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI17534315, Length=317, Percent_Identity=35.6466876971609, Blast_Score=138, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI32566672, Length=212, Percent_Identity=37.7358490566038, Blast_Score=135, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6321594, Length=316, Percent_Identity=38.2911392405063, Blast_Score=181, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6321449, Length=333, Percent_Identity=31.8318318318318, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24643623, Length=311, Percent_Identity=37.620578778135, Blast_Score=168, Evalue=4e-42,
Organism=Drosophila melanogaster, GI20129101, Length=311, Percent_Identity=37.620578778135, Blast_Score=168, Evalue=4e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001216
- InterPro:   IPR005856
- InterPro:   IPR005858
- InterPro:   IPR001926 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =2.5.1.47 [H]

Molecular weight: Translated: 32493; Mature: 32361

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS00901 CYS_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYKTIEDTIGNTPLVQLVRLPDDEIRSRNNVILAKLEGNNPAGSVKDRPALSMIKKAEA
CCCCCHHHHCCCCCCEEEEECCCHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHH
RGRIKPGDTLIESTSGNTGIALAMAAAIRGYKMVLIMPEDLSVERRQSMAAYGAQIVLTP
CCCCCCCCCEEECCCCCCHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEE
VTGGMEYARDLAEQMQREGKGIILDQFANPDNPAAHVEGTGPEIWRDTEGRITHFVSSMG
CCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEECCCCHHHEECCCCHHHHHHHHCC
TTGTIMGVSTYLKEQNQAIEIIGAQPEEGSRIPGIRKWPEAYLPKIFDRSRVDRVENVSQ
CCEEHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AAAEAMARRMASVEGIFAGISSGGACEVALRVARQVENATIVFIVCDRGDRYLSTGVFPA
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEECCCCCCC
>Mature Secondary Structure 
AYKTIEDTIGNTPLVQLVRLPDDEIRSRNNVILAKLEGNNPAGSVKDRPALSMIKKAEA
CCCCHHHHCCCCCCEEEEECCCHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHH
RGRIKPGDTLIESTSGNTGIALAMAAAIRGYKMVLIMPEDLSVERRQSMAAYGAQIVLTP
CCCCCCCCCEEECCCCCCHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEE
VTGGMEYARDLAEQMQREGKGIILDQFANPDNPAAHVEGTGPEIWRDTEGRITHFVSSMG
CCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEECCCCHHHEECCCCHHHHHHHHCC
TTGTIMGVSTYLKEQNQAIEIIGAQPEEGSRIPGIRKWPEAYLPKIFDRSRVDRVENVSQ
CCEEHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AAAEAMARRMASVEGIFAGISSGGACEVALRVARQVENATIVFIVCDRGDRYLSTGVFPA
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]