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The map label for this gene is zraR [H]

Identifier: 91784764

GI number: 91784764

Start: 3753385

End: 3754779

Strand: Reverse

Name: zraR [H]

Synonym: Bxe_A1029

Alternate gene names: 91784764

Gene position: 3754779-3753385 (Counterclockwise)

Preceding gene: 91784774

Following gene: 91784763

Centisome position: 76.69

GC content: 64.52

Gene sequence:

>1395_bases
ATGGAACCCGCAACGCGACAACTGATTTACGTTTCGCGCGATCCCAGCGCGGAGCTGAATATCCGGTTTCATCAGCGCGG
CTGGCACGTCGAAGTCGTGGGGTCGGCGCGCGACGTGCGCCGGGCTGTTCGCGCCGGCATGGCGGCGGGCGGTTTGCTTG
ATCTGTCTAGCGATTTTCAGCCACACGAAATCGCTGCCTTCGAATCGTGCCTGACCATGCCGAATGTCGGCTGGGTTGCG
GCAACCATGCCTGGTCAACTGCAGGACGCCGCCTTGCGCCGGCTCGTGCGCGACTATTGTTTCGATTATGTGACGGTGCC
GTATTCGGGCGACAGGATCGTCGACTCGGTGGGTCATGCATACGGCATGATTTCATTGGGTGAACCGGCTTCCAACGACG
CCTCGCAAGGCGCCGAAGGCGAAATGGTCGGCTCGTGCGACGCCATGCTCGCGCTGTTCCGCTCGATCCGCAAAGTGGCG
ATGACCGACGCGCCGGTGTTCATCTCGGGCGAATCGGGCACCGGCAAGGAACTGACCGCGGTGGCGATTCACGAACGCTC
CGCGCGGCGCAACGCGCCTTTTGTGCCGATCAACTGCGGCGCGATTCCGCCGCATCTTCTGCAATCCGAATTATTCGGCT
ACGAGCGCGGCGCGTTCACCGGCGCCAATCAGCGCAAGATCGGCCGGGTGGAAGCGGCCAACGGCGGCACGCTGTTTCTC
GACGAAATCGGCGACCTGCCGCTCGAAAGCCAGGCGAGCCTGCTGCGCTTTCTGCAGGAACGCAAAGTGGAGCGGCTGGG
AGGGCATGGCGCGATCGACGTCGACGTGCGCATCATTTCGGCCACCCACGTGGATATGACCGCGGCGATGATCGAAGGGC
GTTTCCGTTCCGACCTGTATCACCGCTTATGCGTGCTGCAGATCGACGAACCGCCGCTGCGCGCACGTGGTAAGGATATC
GAACTGCTTGCCCGGCACATGCTCGAACGTTTCAAGAAGGATGCAAGCCGCCGCTTGCGCGGCTTCGCGCCGGATGCGAT
CGCGGCACTGCATAACTACGGCTGGCCGGGCAATGTGCGCGAGCTGATCAACCGGGTGCGGCGCGCTATCGTGATGTCGG
AAGGGCGCGCGATCACGGCACGCGATCTGGAGCTCGCCGAATACGTGGAGATCGTGCCTGTGTCGCTCGCGCAGGCGCGC
GAAGCGGCCGAACGGCAGGCGATCGAACTGGCGCTGCTGCGTCACCGCGGGCGTCTCGGCGACGCCGCGCAGGAGCTCGG
CATCTCGCGCGTCACGCTGTACCGGCTGCTGTGCTCGCACGGCATGCGGCATATGGAAGGCGAGCCGCTCGCTACGCCGC
ACGGCGACTTGCCGGCTTCGGTGCCGCATCTGTAA

Upstream 100 bases:

>100_bases
GGTTTTTGCTTTTTCGCGAATCCCGAATGAGTCAGCGTGTCTGAACTCGGTTCAGGTGCGTGCGTCATCCTTAACGTTCG
TTGACGAGAGGATCTGAATA

Downstream 100 bases:

>100_bases
TCGTTTGGCAGGCCGCGTGGTTCCAGCAGGCTCGCAAAACGGTTTCAGGGATGGTTCAGGGCGCGGTGGCCGTGCCGTGA
CCGGCTGCGCGTTGCCCGCG

Product: sigma-54 dependent trancsriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MEPATRQLIYVSRDPSAELNIRFHQRGWHVEVVGSARDVRRAVRAGMAAGGLLDLSSDFQPHEIAAFESCLTMPNVGWVA
ATMPGQLQDAALRRLVRDYCFDYVTVPYSGDRIVDSVGHAYGMISLGEPASNDASQGAEGEMVGSCDAMLALFRSIRKVA
MTDAPVFISGESGTGKELTAVAIHERSARRNAPFVPINCGAIPPHLLQSELFGYERGAFTGANQRKIGRVEAANGGTLFL
DEIGDLPLESQASLLRFLQERKVERLGGHGAIDVDVRIISATHVDMTAAMIEGRFRSDLYHRLCVLQIDEPPLRARGKDI
ELLARHMLERFKKDASRRLRGFAPDAIAALHNYGWPGNVRELINRVRRAIVMSEGRAITARDLELAEYVEIVPVSLAQAR
EAAERQAIELALLRHRGRLGDAAQELGISRVTLYRLLCSHGMRHMEGEPLATPHGDLPASVPHL

Sequences:

>Translated_464_residues
MEPATRQLIYVSRDPSAELNIRFHQRGWHVEVVGSARDVRRAVRAGMAAGGLLDLSSDFQPHEIAAFESCLTMPNVGWVA
ATMPGQLQDAALRRLVRDYCFDYVTVPYSGDRIVDSVGHAYGMISLGEPASNDASQGAEGEMVGSCDAMLALFRSIRKVA
MTDAPVFISGESGTGKELTAVAIHERSARRNAPFVPINCGAIPPHLLQSELFGYERGAFTGANQRKIGRVEAANGGTLFL
DEIGDLPLESQASLLRFLQERKVERLGGHGAIDVDVRIISATHVDMTAAMIEGRFRSDLYHRLCVLQIDEPPLRARGKDI
ELLARHMLERFKKDASRRLRGFAPDAIAALHNYGWPGNVRELINRVRRAIVMSEGRAITARDLELAEYVEIVPVSLAQAR
EAAERQAIELALLRHRGRLGDAAQELGISRVTLYRLLCSHGMRHMEGEPLATPHGDLPASVPHL
>Mature_464_residues
MEPATRQLIYVSRDPSAELNIRFHQRGWHVEVVGSARDVRRAVRAGMAAGGLLDLSSDFQPHEIAAFESCLTMPNVGWVA
ATMPGQLQDAALRRLVRDYCFDYVTVPYSGDRIVDSVGHAYGMISLGEPASNDASQGAEGEMVGSCDAMLALFRSIRKVA
MTDAPVFISGESGTGKELTAVAIHERSARRNAPFVPINCGAIPPHLLQSELFGYERGAFTGANQRKIGRVEAANGGTLFL
DEIGDLPLESQASLLRFLQERKVERLGGHGAIDVDVRIISATHVDMTAAMIEGRFRSDLYHRLCVLQIDEPPLRARGKDI
ELLARHMLERFKKDASRRLRGFAPDAIAALHNYGWPGNVRELINRVRRAIVMSEGRAITARDLELAEYVEIVPVSLAQAR
EAAERQAIELALLRHRGRLGDAAQELGISRVTLYRLLCSHGMRHMEGEPLATPHGDLPASVPHL

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=342, Percent_Identity=45.3216374269006, Blast_Score=268, Evalue=5e-73,
Organism=Escherichia coli, GI1788550, Length=357, Percent_Identity=42.296918767507, Blast_Score=263, Evalue=2e-71,
Organism=Escherichia coli, GI1790299, Length=371, Percent_Identity=40.4312668463612, Blast_Score=250, Evalue=2e-67,
Organism=Escherichia coli, GI1788905, Length=344, Percent_Identity=41.2790697674419, Blast_Score=248, Evalue=8e-67,
Organism=Escherichia coli, GI87082117, Length=281, Percent_Identity=45.9074733096085, Blast_Score=245, Evalue=6e-66,
Organism=Escherichia coli, GI1789233, Length=313, Percent_Identity=44.408945686901, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI1789087, Length=342, Percent_Identity=40.3508771929825, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI1786524, Length=319, Percent_Identity=42.9467084639498, Blast_Score=210, Evalue=1e-55,
Organism=Escherichia coli, GI87082152, Length=324, Percent_Identity=40.4320987654321, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI87081872, Length=314, Percent_Identity=38.2165605095541, Blast_Score=195, Evalue=6e-51,
Organism=Escherichia coli, GI1787583, Length=335, Percent_Identity=34.6268656716418, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI87081858, Length=293, Percent_Identity=32.4232081911263, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1789828, Length=242, Percent_Identity=34.7107438016529, Blast_Score=126, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 50985; Mature: 50985

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPATRQLIYVSRDPSAELNIRFHQRGWHVEVVGSARDVRRAVRAGMAAGGLLDLSSDFQ
CCCCCCEEEEEECCCCCEEEEEEECCCCEEEEECCHHHHHHHHHHCCCCCCCEECCCCCC
PHEIAAFESCLTMPNVGWVAATMPGQLQDAALRRLVRDYCFDYVTVPYSGDRIVDSVGHA
CHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCEEECCCCCCHHHHHHHHH
YGMISLGEPASNDASQGAEGEMVGSCDAMLALFRSIRKVAMTDAPVFISGESGTGKELTA
HEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEE
VAIHERSARRNAPFVPINCGAIPPHLLQSELFGYERGAFTGANQRKIGRVEAANGGTLFL
EEEEHHHHCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCEEEE
DEIGDLPLESQASLLRFLQERKVERLGGHGAIDVDVRIISATHVDMTAAMIEGRFRSDLY
ECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHH
HRLCVLQIDEPPLRARGKDIELLARHMLERFKKDASRRLRGFAPDAIAALHNYGWPGNVR
HCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHH
ELINRVRRAIVMSEGRAITARDLELAEYVEIVPVSLAQAREAAERQAIELALLRHRGRLG
HHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DAAQELGISRVTLYRLLCSHGMRHMEGEPLATPHGDLPASVPHL
CHHHHHCCHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MEPATRQLIYVSRDPSAELNIRFHQRGWHVEVVGSARDVRRAVRAGMAAGGLLDLSSDFQ
CCCCCCEEEEEECCCCCEEEEEEECCCCEEEEECCHHHHHHHHHHCCCCCCCEECCCCCC
PHEIAAFESCLTMPNVGWVAATMPGQLQDAALRRLVRDYCFDYVTVPYSGDRIVDSVGHA
CHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCEEECCCCCCHHHHHHHHH
YGMISLGEPASNDASQGAEGEMVGSCDAMLALFRSIRKVAMTDAPVFISGESGTGKELTA
HEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEE
VAIHERSARRNAPFVPINCGAIPPHLLQSELFGYERGAFTGANQRKIGRVEAANGGTLFL
EEEEHHHHCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCEEEE
DEIGDLPLESQASLLRFLQERKVERLGGHGAIDVDVRIISATHVDMTAAMIEGRFRSDLY
ECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHH
HRLCVLQIDEPPLRARGKDIELLARHMLERFKKDASRRLRGFAPDAIAALHNYGWPGNVR
HCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHH
ELINRVRRAIVMSEGRAITARDLELAEYVEIVPVSLAQAREAAERQAIELALLRHRGRLG
HHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DAAQELGISRVTLYRLLCSHGMRHMEGEPLATPHGDLPASVPHL
CHHHHHCCHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]