Click here to switch to the map view.

The map label for this gene is uvrY [H]

Identifier: 91784340

GI number: 91784340

Start: 3304001

End: 3304633

Strand: Reverse

Name: uvrY [H]

Synonym: Bxe_A1460

Alternate gene names: 91784340

Gene position: 3304633-3304001 (Counterclockwise)

Preceding gene: 91784341

Following gene: 91784339

Centisome position: 67.5

GC content: 61.14

Gene sequence:

>633_bases
ATGATTCGAGTGTTGATAGCTGACGACCATGCGATCGTCCGAGGTGGCTTCAGGCAGTTCGTCGCTGACGAGCCGGATAT
GTGCGTCGCGGCTGAAGCGGCCACCGGCGACGAAACCATCAGCCTCGTGCGCGAGCAGGCGTTCGACGTGGTGCTGCTCG
ACATCGCGATGCCGGACAAGAACGGCATCGACACCTTGCGCGTGATCAAGCAGGTGCGCCCGGAGCAGGGCGTGCTGATT
TTATCGGGCTACCCGGAGAGCCAGTACGCGATCAACCTGCTGCGCGCGGGTGCCAACGGTTATCTGAACAAGGATTGCGA
GCCCGACGAGATCGTGCGGGCAATTCGCGCGGTAGCGCGCGGGCACCGTTATCTCTCCGAGGCGGTCGCCGATACGCTCG
CCGACAACCTCGACAAACCGGCTGTCGGGCGGCCGCATGAAGCGCTCTCCGAGCGCGAGTTCCAGATCTTCTGCAAGCTC
GCGGCGGGGCAGATTCCCACGGAGATTGCGGAGGAACTGCATTTGTCCGTGAAGACGGTCAGTACCTATCGGGCCCGTGT
GCTGGAGAAAATGCGGTTGGCGAATAATGCCGATCTGACTTATTACGCGATCAAGAACGGCCTGATCGAATAA

Upstream 100 bases:

>100_bases
CGCCATGCGCCGCCGGGTTTTGCGATTCCGGCAGAAGCCAGACCGGAGGTCATTACAATGTCTGCTTTGGAGCGACTCCA
TTGCACGGACACCCAAACCG

Downstream 100 bases:

>100_bases
TGGACGATCGAGATATGCCGATGAACAGCGAATCCAACCCTGTTGCCGAGCCGGCCAGCCGCACGCCATTGCGCGTGTTG
CTGATCGAGGATTCGCCGCT

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MIRVLIADDHAIVRGGFRQFVADEPDMCVAAEAATGDETISLVREQAFDVVLLDIAMPDKNGIDTLRVIKQVRPEQGVLI
LSGYPESQYAINLLRAGANGYLNKDCEPDEIVRAIRAVARGHRYLSEAVADTLADNLDKPAVGRPHEALSEREFQIFCKL
AAGQIPTEIAEELHLSVKTVSTYRARVLEKMRLANNADLTYYAIKNGLIE

Sequences:

>Translated_210_residues
MIRVLIADDHAIVRGGFRQFVADEPDMCVAAEAATGDETISLVREQAFDVVLLDIAMPDKNGIDTLRVIKQVRPEQGVLI
LSGYPESQYAINLLRAGANGYLNKDCEPDEIVRAIRAVARGHRYLSEAVADTLADNLDKPAVGRPHEALSEREFQIFCKL
AAGQIPTEIAEELHLSVKTVSTYRARVLEKMRLANNADLTYYAIKNGLIE
>Mature_210_residues
MIRVLIADDHAIVRGGFRQFVADEPDMCVAAEAATGDETISLVREQAFDVVLLDIAMPDKNGIDTLRVIKQVRPEQGVLI
LSGYPESQYAINLLRAGANGYLNKDCEPDEIVRAIRAVARGHRYLSEAVADTLADNLDKPAVGRPHEALSEREFQIFCKL
AAGQIPTEIAEELHLSVKTVSTYRARVLEKMRLANNADLTYYAIKNGLIE

Specific function: Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. UvrY activates the transcription of the untranslated csrB RNA and of barA, in an autoregulatory loop. Mediates the

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=209, Percent_Identity=37.3205741626794, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI1790102, Length=199, Percent_Identity=38.1909547738693, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1788521, Length=190, Percent_Identity=35.2631578947368, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1786747, Length=201, Percent_Identity=28.8557213930348, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1787473, Length=182, Percent_Identity=31.8681318681319, Blast_Score=90, Evalue=9e-20,
Organism=Escherichia coli, GI1788712, Length=211, Percent_Identity=27.0142180094787, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788546, Length=204, Percent_Identity=26.9607843137255, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790437, Length=103, Percent_Identity=36.8932038834951, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23206; Mature: 23206

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRVLIADDHAIVRGGFRQFVADEPDMCVAAEAATGDETISLVREQAFDVVLLDIAMPDK
CEEEEEECCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHCEEEEEEECCCC
NGIDTLRVIKQVRPEQGVLILSGYPESQYAINLLRAGANGYLNKDCEPDEIVRAIRAVAR
CCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
GHRYLSEAVADTLADNLDKPAVGRPHEALSEREFQIFCKLAAGQIPTEIAEELHLSVKTV
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCHHHHHEEHHCCCCCHHHHHHHHHHHHHH
STYRARVLEKMRLANNADLTYYAIKNGLIE
HHHHHHHHHHHHHCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MIRVLIADDHAIVRGGFRQFVADEPDMCVAAEAATGDETISLVREQAFDVVLLDIAMPDK
CEEEEEECCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHCEEEEEEECCCC
NGIDTLRVIKQVRPEQGVLILSGYPESQYAINLLRAGANGYLNKDCEPDEIVRAIRAVAR
CCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
GHRYLSEAVADTLADNLDKPAVGRPHEALSEREFQIFCKLAAGQIPTEIAEELHLSVKTV
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCHHHHHEEHHCCCCCHHHHHHHHHHHHHH
STYRARVLEKMRLANNADLTYYAIKNGLIE
HHHHHHHHHHHHHCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]