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The map label for this gene is cysS

Identifier: 91784175

GI number: 91784175

Start: 3114218

End: 3115615

Strand: Reverse

Name: cysS

Synonym: Bxe_A1626

Alternate gene names: 91784175

Gene position: 3115615-3114218 (Counterclockwise)

Preceding gene: 91784180

Following gene: 91784174

Centisome position: 63.64

GC content: 61.73

Gene sequence:

>1398_bases
ATGGAATCACTGCGCATCTACAACACGCTCGCGCGTGACAAGCAAACTTTCGTGCCGCTGCAAGACGGTGTCGTGCGGAT
GTACGTCTGCGGGATGACCGTGTACGACTATTGTCACGTCGGTCATGCGCGGGTGATGGTCGTGTTCGACATCGTGCAGC
GCTGGTTGCGCACGCTCGGCTATAACGTGACCTACGTGCGCAATATCACCGATATTGATGACAAGATCATCCGCCGCGCG
GTCGAGAATGGCGAAACGATCAAGTCGCTGACCGACCGGTTCATCAAGGCACTGCATGAAGACGCGGACGCGCTCGGCAT
CCAGCGGCCCGACATCGAGCCGCGCGCGACTGATTTCATTCCGCAGATGCTCGGCATGATCGAGCGGCTCGAAGCGAACG
GCTACGCCTATCAGGCGAGCGACGGCGACGTGAACTACGCGGTGCGCAAGTTCGCGAACTACGGCAAGCTCTCGGGCAAA
TCGCTCGAAGATCTGCGCGCGGGCGAACGCGTCGCGGCGAACGACGCGAAGCAGGACCCGCTCGACTTCGTGCTGTGGAA
GCAGGCCAAGCCGCAAGAACCCGCCGACACCGGCTGGGATTCGAAGTACGGGCGCGGCCGTCCGGGCTGGCATATCGAAT
GCTCGGCAATGGGTTGCACGTTGCTCGGCGAACATTTTGACATTCATGGCGGCGGCCAGGACCTGCAGTTTCCGCACCAC
GAAAACGAGATTGCGCAAAGTGAAGCCGCTACCGGTCAAACCTTCGTCAATTTCTGGATGCACAACGGCTACGTACAGAT
CGACAATGAGAAGATGTCGAAGTCGTTGAACAACTTCTTTACGATTCGCGAAGTGTTGGCGCAGTACGACGCCGAGGTCG
TGCGGTTTTTCATCGCGCGTGCGCATTACCGCTCGCCGCTGAACTACAGCGACGTGCATATCGACGACGCCCGCAACGCC
CTCACGCGTCTGTACACCGCGCTGAAGGACGTCACGCCCGACGGCGCGGAACTCGACTGGAACGAAGCGTATGCGCAGCG
TTTCCAGGCAGCAATGAACGACGACTTCAACACGCCGGTCGCGGTATCGGTGTTGTTCGAGTTGGCAAGTGAAGTGAACC
GCACGCGCGACCCCGCGCTGGCCCGTCAATTGCGTTTGCTTGGCGCGGTAATCGGACTGCTCGGCCGTGAGCCGCGTGCC
TATCTGCAGCAGGCAGCGGGCGCAGCAGCGGTGGGCGCGCTCGAGGCCGCCGCGATCGAAGCGAAGATTGCCGCGCGCGC
GGCCGCGAAGCAGGCGAAGGACTTTGCGGCGGCAGACCGGATCCGGTCCGAATTGCTCGAGGCCGGCGTTGCACTTGAAG
ACAAACCCGGCGGGTTGACCGAGTGGCGGCGCGTGTGA

Upstream 100 bases:

>100_bases
GCACCGGTTTTGCTGTACGCGACGCACCCGCCGTCTGTTCGCTGGGCGCGGCGCGCATGAAACACATTGCGGATTTCTTT
CGGCCCACGCACCGTTCTCT

Downstream 100 bases:

>100_bases
GCGCACCTCGAGCTTCCCTTTGATCGACTCGCCAGGCAGGAGGCAGGATGGCAACGGCCACGAAGACGCCGGCTAAACGA
GCCGCGTCTCAAACAAACGC

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MESLRIYNTLARDKQTFVPLQDGVVRMYVCGMTVYDYCHVGHARVMVVFDIVQRWLRTLGYNVTYVRNITDIDDKIIRRA
VENGETIKSLTDRFIKALHEDADALGIQRPDIEPRATDFIPQMLGMIERLEANGYAYQASDGDVNYAVRKFANYGKLSGK
SLEDLRAGERVAANDAKQDPLDFVLWKQAKPQEPADTGWDSKYGRGRPGWHIECSAMGCTLLGEHFDIHGGGQDLQFPHH
ENEIAQSEAATGQTFVNFWMHNGYVQIDNEKMSKSLNNFFTIREVLAQYDAEVVRFFIARAHYRSPLNYSDVHIDDARNA
LTRLYTALKDVTPDGAELDWNEAYAQRFQAAMNDDFNTPVAVSVLFELASEVNRTRDPALARQLRLLGAVIGLLGREPRA
YLQQAAGAAAVGALEAAAIEAKIAARAAAKQAKDFAAADRIRSELLEAGVALEDKPGGLTEWRRV

Sequences:

>Translated_465_residues
MESLRIYNTLARDKQTFVPLQDGVVRMYVCGMTVYDYCHVGHARVMVVFDIVQRWLRTLGYNVTYVRNITDIDDKIIRRA
VENGETIKSLTDRFIKALHEDADALGIQRPDIEPRATDFIPQMLGMIERLEANGYAYQASDGDVNYAVRKFANYGKLSGK
SLEDLRAGERVAANDAKQDPLDFVLWKQAKPQEPADTGWDSKYGRGRPGWHIECSAMGCTLLGEHFDIHGGGQDLQFPHH
ENEIAQSEAATGQTFVNFWMHNGYVQIDNEKMSKSLNNFFTIREVLAQYDAEVVRFFIARAHYRSPLNYSDVHIDDARNA
LTRLYTALKDVTPDGAELDWNEAYAQRFQAAMNDDFNTPVAVSVLFELASEVNRTRDPALARQLRLLGAVIGLLGREPRA
YLQQAAGAAAVGALEAAAIEAKIAARAAAKQAKDFAAADRIRSELLEAGVALEDKPGGLTEWRRV
>Mature_465_residues
MESLRIYNTLARDKQTFVPLQDGVVRMYVCGMTVYDYCHVGHARVMVVFDIVQRWLRTLGYNVTYVRNITDIDDKIIRRA
VENGETIKSLTDRFIKALHEDADALGIQRPDIEPRATDFIPQMLGMIERLEANGYAYQASDGDVNYAVRKFANYGKLSGK
SLEDLRAGERVAANDAKQDPLDFVLWKQAKPQEPADTGWDSKYGRGRPGWHIECSAMGCTLLGEHFDIHGGGQDLQFPHH
ENEIAQSEAATGQTFVNFWMHNGYVQIDNEKMSKSLNNFFTIREVLAQYDAEVVRFFIARAHYRSPLNYSDVHIDDARNA
LTRLYTALKDVTPDGAELDWNEAYAQRFQAAMNDDFNTPVAVSVLFELASEVNRTRDPALARQLRLLGAVIGLLGREPRA
YLQQAAGAAAVGALEAAAIEAKIAARAAAKQAKDFAAADRIRSELLEAGVALEDKPGGLTEWRRV

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI13375695, Length=410, Percent_Identity=37.3170731707317, Blast_Score=247, Evalue=2e-65,
Organism=Homo sapiens, GI21269877, Length=300, Percent_Identity=36.6666666666667, Blast_Score=186, Evalue=6e-47,
Organism=Homo sapiens, GI62240992, Length=300, Percent_Identity=36.6666666666667, Blast_Score=185, Evalue=6e-47,
Organism=Homo sapiens, GI303304987, Length=300, Percent_Identity=36.6666666666667, Blast_Score=185, Evalue=7e-47,
Organism=Homo sapiens, GI10835051, Length=300, Percent_Identity=36.6666666666667, Blast_Score=185, Evalue=9e-47,
Organism=Escherichia coli, GI1786737, Length=471, Percent_Identity=55.8386411889597, Blast_Score=492, Evalue=1e-140,
Organism=Caenorhabditis elegans, GI17509795, Length=294, Percent_Identity=33.6734693877551, Blast_Score=167, Evalue=8e-42,
Organism=Caenorhabditis elegans, GI17509797, Length=294, Percent_Identity=33.6734693877551, Blast_Score=167, Evalue=9e-42,
Organism=Saccharomyces cerevisiae, GI6324082, Length=440, Percent_Identity=29.7727272727273, Blast_Score=197, Evalue=2e-51,
Organism=Drosophila melanogaster, GI19922218, Length=504, Percent_Identity=32.3412698412698, Blast_Score=225, Evalue=5e-59,
Organism=Drosophila melanogaster, GI19922364, Length=449, Percent_Identity=31.8485523385301, Blast_Score=179, Evalue=5e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYC_BURXL (Q13X60)

Other databases:

- EMBL:   CP000270
- RefSeq:   YP_559381.1
- ProteinModelPortal:   Q13X60
- SMR:   Q13X60
- GeneID:   4003755
- GenomeReviews:   CP000270_GR
- KEGG:   bxe:Bxe_A1626
- HOGENOM:   HBG327651
- OMA:   DFDALNM
- ProtClustDB:   PRK00260
- GO:   GO:0005737
- HAMAP:   MF_00041_B
- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR10890
- PRINTS:   PR00983
- SMART:   SM00840
- TIGRFAMs:   TIGR00435

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.16

Molecular weight: Translated: 52066; Mature: 52066

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 274-274

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESLRIYNTLARDKQTFVPLQDGVVRMYVCGMTVYDYCHVGHARVMVVFDIVQRWLRTLG
CCCHHHHHHHHCCCCCCCCHHCCCEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHC
YNVTYVRNITDIDDKIIRRAVENGETIKSLTDRFIKALHEDADALGIQRPDIEPRATDFI
CCEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCHHHHHH
PQMLGMIERLEANGYAYQASDGDVNYAVRKFANYGKLSGKSLEDLRAGERVAANDAKQDP
HHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHCCCHHHCCCCCCCC
LDFVLWKQAKPQEPADTGWDSKYGRGRPGWHIECSAMGCTLLGEHFDIHGGGQDLQFPHH
HHHHEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHCCCEEECCCCCCCCCCCC
ENEIAQSEAATGQTFVNFWMHNGYVQIDNEKMSKSLNNFFTIREVLAQYDAEVVRFFIAR
HHHHHHHHHCCCHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHYRSPLNYSDVHIDDARNALTRLYTALKDVTPDGAELDWNEAYAQRFQAAMNDDFNTPV
HHHCCCCCCCCEEECHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCHH
AVSVLFELASEVNRTRDPALARQLRLLGAVIGLLGREPRAYLQQAAGAAAVGALEAAAIE
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHH
AKIAARAAAKQAKDFAAADRIRSELLEAGVALEDKPGGLTEWRRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCC
>Mature Secondary Structure
MESLRIYNTLARDKQTFVPLQDGVVRMYVCGMTVYDYCHVGHARVMVVFDIVQRWLRTLG
CCCHHHHHHHHCCCCCCCCHHCCCEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHC
YNVTYVRNITDIDDKIIRRAVENGETIKSLTDRFIKALHEDADALGIQRPDIEPRATDFI
CCEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCHHHHHH
PQMLGMIERLEANGYAYQASDGDVNYAVRKFANYGKLSGKSLEDLRAGERVAANDAKQDP
HHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHCCCHHHCCCCCCCC
LDFVLWKQAKPQEPADTGWDSKYGRGRPGWHIECSAMGCTLLGEHFDIHGGGQDLQFPHH
HHHHEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHCCCEEECCCCCCCCCCCC
ENEIAQSEAATGQTFVNFWMHNGYVQIDNEKMSKSLNNFFTIREVLAQYDAEVVRFFIAR
HHHHHHHHHCCCHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHYRSPLNYSDVHIDDARNALTRLYTALKDVTPDGAELDWNEAYAQRFQAAMNDDFNTPV
HHHCCCCCCCCEEECHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCHH
AVSVLFELASEVNRTRDPALARQLRLLGAVIGLLGREPRAYLQQAAGAAAVGALEAAAIE
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHH
AKIAARAAAKQAKDFAAADRIRSELLEAGVALEDKPGGLTEWRRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA