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The map label for this gene is yfjP [H]

Identifier: 91784174

GI number: 91784174

Start: 3113121

End: 3113966

Strand: Reverse

Name: yfjP [H]

Synonym: Bxe_A1627

Alternate gene names: 91784174

Gene position: 3113966-3113121 (Counterclockwise)

Preceding gene: 91784175

Following gene: 91784173

Centisome position: 63.6

GC content: 65.84

Gene sequence:

>846_bases
GTGCATGCGCCCGTCGCGAAACGCGCGAAGGCGCCGCGTGCGAAGAGCAATGGCGCATTGCCGGCTGAACTGGCCGGCGA
CGTGCGGGAACTGGCCCGTGTGACAGGCGAGGGGCACGAAGGCGAAGTCGTGCGCAAGACGCGCGCATCCGCTGCCGCGG
GTGGCGAAGGGGCGAGCGCGAGCGAAGTCGCGGTGCCGGTGCAGATCGGCGGTCTCACGCCTGAAGTGACGCGGCCCGCG
TATTGGGACAAGGCGTGTGCCGACCTCGTCAAGCGCGACCGCATTCTGAAGAAGCTGATTCCGAAGTTCGGTCCGGTGCA
TCTGCTGAGCCGCGGCGATCCGTTCGTCACGCTCGCGCGCTCGGTGGTCGGACAGCAGATTTCCGTGGCCTCCGCGCAAG
CGGCCTGGGCGAAAGTCGAGGCCGCCTGTCCGAAGCTGGTGCCGCAGCAGTTCATCAAGCTCGGTCTGGAAAAGCTGACC
ACGTGCGGGTTGTCCAAACGCAAGGCCGAGTACGTGCTCGATCTCGCGCAGCATTTCGTTTCGGGTGCGCTGCACGTCGG
CAAATGGACGTCGATGGAAGACGAGGCGGTGATTGCCGAACTCACGCAGATTCGCGGCATTGGCCGCTGGACCGCGGAGA
TGTTCCTGATCTTCAATCTGTCGCGCCCGGATGTCCTGCCGCTCGACGACCTCGGGCTGATCCGCGCGATCAGCGTCAAC
TATTTCAGCGGCGAGCCGGTCACGCGCAGCGAAGCACGCGAGGTCGCCGCCAACTGGGAACCGTGGCGCACCGTCGCCAC
CTGGTATATGTGGCGTAGTCTCGACCCGCTGCCGGTCGACTACTGA

Upstream 100 bases:

>100_bases
GGTAAAGAAAGCATCGTCGAAAGCCGCCGGGGCGGCGGCCGGGATCGCAGCGGGCGCATCGAAAAAGACTTCGGTCAAAC
GCGCGCTCAACGGCGCGTCG

Downstream 100 bases:

>100_bases
AGAACAAGAAACGGGATCGGATCAAAACTATCGATTGTTAAAGATTGATAGTTGAGAAATGGTTTTGACATCGGCGAGCG
CGGTTAGAATACGCGCTGCC

Product: HhH-GPD superfamily base excision DNA repair protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MHAPVAKRAKAPRAKSNGALPAELAGDVRELARVTGEGHEGEVVRKTRASAAAGGEGASASEVAVPVQIGGLTPEVTRPA
YWDKACADLVKRDRILKKLIPKFGPVHLLSRGDPFVTLARSVVGQQISVASAQAAWAKVEAACPKLVPQQFIKLGLEKLT
TCGLSKRKAEYVLDLAQHFVSGALHVGKWTSMEDEAVIAELTQIRGIGRWTAEMFLIFNLSRPDVLPLDDLGLIRAISVN
YFSGEPVTRSEAREVAANWEPWRTVATWYMWRSLDPLPVDY

Sequences:

>Translated_281_residues
MHAPVAKRAKAPRAKSNGALPAELAGDVRELARVTGEGHEGEVVRKTRASAAAGGEGASASEVAVPVQIGGLTPEVTRPA
YWDKACADLVKRDRILKKLIPKFGPVHLLSRGDPFVTLARSVVGQQISVASAQAAWAKVEAACPKLVPQQFIKLGLEKLT
TCGLSKRKAEYVLDLAQHFVSGALHVGKWTSMEDEAVIAELTQIRGIGRWTAEMFLIFNLSRPDVLPLDDLGLIRAISVN
YFSGEPVTRSEAREVAANWEPWRTVATWYMWRSLDPLPVDY
>Mature_281_residues
MHAPVAKRAKAPRAKSNGALPAELAGDVRELARVTGEGHEGEVVRKTRASAAAGGEGASASEVAVPVQIGGLTPEVTRPA
YWDKACADLVKRDRILKKLIPKFGPVHLLSRGDPFVTLARSVVGQQISVASAQAAWAKVEAACPKLVPQQFIKLGLEKLT
TCGLSKRKAEYVLDLAQHFVSGALHVGKWTSMEDEAVIAELTQIRGIGRWTAEMFLIFNLSRPDVLPLDDLGLIRAISVN
YFSGEPVTRSEAREVAANWEPWRTVATWYMWRSLDPLPVDY

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, 3-methylguanine, 7-methylguanine, O2- methylthymine, and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG0122

COG function: function code L; 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alkylbase DNA glycosidase alkA family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320990, Length=197, Percent_Identity=32.48730964467, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR003265
- InterPro:   IPR003583
- InterPro:   IPR023170 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: =3.2.2.21 [H]

Molecular weight: Translated: 30599; Mature: 30599

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: PS00037 MYB_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHAPVAKRAKAPRAKSNGALPAELAGDVRELARVTGEGHEGEVVRKTRASAAAGGEGASA
CCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCC
SEVAVPVQIGGLTPEVTRPAYWDKACADLVKRDRILKKLIPKFGPVHLLSRGDPFVTLAR
CCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHH
SVVGQQISVASAQAAWAKVEAACPKLVPQQFIKLGLEKLTTCGLSKRKAEYVLDLAQHFV
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
SGALHVGKWTSMEDEAVIAELTQIRGIGRWTAEMFLIFNLSRPDVLPLDDLGLIRAISVN
HCCHHCCCCCCCCHHHHHHHHHHHHCCHHHHEEEEEEEECCCCCCCCCCCCCHHHHEEEE
YFSGEPVTRSEAREVAANWEPWRTVATWYMWRSLDPLPVDY
EECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MHAPVAKRAKAPRAKSNGALPAELAGDVRELARVTGEGHEGEVVRKTRASAAAGGEGASA
CCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCC
SEVAVPVQIGGLTPEVTRPAYWDKACADLVKRDRILKKLIPKFGPVHLLSRGDPFVTLAR
CCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHH
SVVGQQISVASAQAAWAKVEAACPKLVPQQFIKLGLEKLTTCGLSKRKAEYVLDLAQHFV
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
SGALHVGKWTSMEDEAVIAELTQIRGIGRWTAEMFLIFNLSRPDVLPLDDLGLIRAISVN
HCCHHCCCCCCCCHHHHHHHHHHHHCCHHHHEEEEEEEECCCCCCCCCCCCCHHHHEEEE
YFSGEPVTRSEAREVAANWEPWRTVATWYMWRSLDPLPVDY
EECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]