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The map label for this gene is fabZ [H]

Identifier: 91784108

GI number: 91784108

Start: 3034664

End: 3035128

Strand: Reverse

Name: fabZ [H]

Synonym: Bxe_A1693

Alternate gene names: 91784108

Gene position: 3035128-3034664 (Counterclockwise)

Preceding gene: 91784109

Following gene: 91784107

Centisome position: 61.99

GC content: 58.28

Gene sequence:

>465_bases
ATGAGCACCGAAAAAATCAATCTCGACATTCATAAGATTCTCACGCTGCTGCCACATCGTTACCCGATCCTGCTGGTGGA
CCGGGTGCTCGAACTCGAGCCGCACAAGAACATCAAAGCGTTGAAGAACGTGTCGATCAACGAACCGTATTTCCAGGGCC
ACTTTCCGACCCGTCCGGTCATGCCGGGCGTGCTGATTCTCGAAGCGCTCGCGCAAACGGCGGCTTTGCTGACGTTTTCG
GAAGAGCCGAGCGACCCGTCGAACACGCTGTATCTGTTCGTCGGCATCGACAATGCACGCTTCAAGCGCGTGGTGGAACC
GGGCGATCAGCTGATCCTGAACTGCACGTTCGAGCGTCATATGCGCGGCATCTGGAAGTTCAAGGCGCGCGCCGAAGTGG
ATGGCGTAGTAGCGGCGGAAGCCGACCTGATGTGCGCGGTGCGGCACACGGACAAGGACGCTTGA

Upstream 100 bases:

>100_bases
GCCGCCGGGTTATGGCGAGCGCCGGCAGCATGCGTTATCAACCCACCTGCACCAGCATCCGCAGTCATCATCGCGCAGTC
AATGCGTGAGTAGAAACACC

Downstream 100 bases:

>100_bases
GCTAGCGTCCCGGCGCTCAGCGGCGCGACGCGTGCGCTGAGCGCCCCGCCAGATGCCCACCCAGACAACGCAACAGAATC
AGAAGCGAGGACGCATGAGC

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: trans-Delta2-enoyl-acyl-ACP; H2O [C]

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 154; Mature: 153

Protein sequence:

>154_residues
MSTEKINLDIHKILTLLPHRYPILLVDRVLELEPHKNIKALKNVSINEPYFQGHFPTRPVMPGVLILEALAQTAALLTFS
EEPSDPSNTLYLFVGIDNARFKRVVEPGDQLILNCTFERHMRGIWKFKARAEVDGVVAAEADLMCAVRHTDKDA

Sequences:

>Translated_154_residues
MSTEKINLDIHKILTLLPHRYPILLVDRVLELEPHKNIKALKNVSINEPYFQGHFPTRPVMPGVLILEALAQTAALLTFS
EEPSDPSNTLYLFVGIDNARFKRVVEPGDQLILNCTFERHMRGIWKFKARAEVDGVVAAEADLMCAVRHTDKDA
>Mature_153_residues
STEKINLDIHKILTLLPHRYPILLVDRVLELEPHKNIKALKNVSINEPYFQGHFPTRPVMPGVLILEALAQTAALLTFSE
EPSDPSNTLYLFVGIDNARFKRVVEPGDQLILNCTFERHMRGIWKFKARAEVDGVVAAEADLMCAVRHTDKDA

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=146, Percent_Identity=55.4794520547945, Blast_Score=171, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.- [C]

Molecular weight: Translated: 17430; Mature: 17298

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTEKINLDIHKILTLLPHRYPILLVDRVLELEPHKNIKALKNVSINEPYFQGHFPTRPV
CCCCEECCHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHCCCCCCCEECCCCCCCCC
MPGVLILEALAQTAALLTFSEEPSDPSNTLYLFVGIDNARFKRVVEPGDQLILNCTFERH
CCHHHHHHHHHHHHHEEEECCCCCCCCCEEEEEEECCCHHHHHHCCCCCEEEEEEEHHHH
MRGIWKFKARAEVDGVVAAEADLMCAVRHTDKDA
HHHHHHHHCCCCCCEEEEECCCEEEEEECCCCCC
>Mature Secondary Structure 
STEKINLDIHKILTLLPHRYPILLVDRVLELEPHKNIKALKNVSINEPYFQGHFPTRPV
CCCEECCHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHCCCCCCCEECCCCCCCCC
MPGVLILEALAQTAALLTFSEEPSDPSNTLYLFVGIDNARFKRVVEPGDQLILNCTFERH
CCHHHHHHHHHHHHHEEEECCCCCCCCCEEEEEEECCCHHHHHHCCCCCEEEEEEEHHHH
MRGIWKFKARAEVDGVVAAEADLMCAVRHTDKDA
HHHHHHHHCCCCCCEEEEECCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-3-hydroxy-acyl-ACP [C]

Specific reaction: D-3-hydroxy-acyl-ACP = trans-Delta2-enoyl-acyl-ACP + H2O [C]

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA