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The map label for this gene is lpxA [H]

Identifier: 91784107

GI number: 91784107

Start: 3033781

End: 3034569

Strand: Reverse

Name: lpxA [H]

Synonym: Bxe_A1694

Alternate gene names: 91784107

Gene position: 3034569-3033781 (Counterclockwise)

Preceding gene: 91784108

Following gene: 91784106

Centisome position: 61.98

GC content: 65.15

Gene sequence:

>789_bases
ATGAGCAGGATTCATCCCACTGCGATCGTCGAACCGGGCGCGCAACTCGACGAATCCGTCGAAGTCGGACCGTATGCCGT
GATCGGCGCGCATGTAACGATCGGCGCGCGCACCACGGTCGGTTCGCACAGCGTGATCGAAGGTCACACCACGCTCGGCG
AAGACAATCGGATCGGCCACTACGCATCGGTCGGCGGCCGTCCGCAGGACATGAAGTACAAGGACGAGCCGACCCGGCTC
GTGATCGGCAGCCGCAACACGATCCGCGAGTTCACCACGATCCACACCGGCACGGTGCAGGACTCGGGCGTCACCACACT
CGGCGACGACAACTGGATCATGGCGTACGTGCACATCGGGCACGATTGCCACGTCGGCAACAACGTCATTCTGTCGAGCA
ATGCGCAGATGGCCGGCCACGTCATCATCGGCGACCACGCGATCGTCGGCGGCATGTCGGGCGTCCATCAGTTCGTGCGT
ATCGGCGCGCATTCCATGCTGGGCGGCGCGTCGGCGCTGGTGCAGGACATTCCGCCGTTCGTGATCGCCGCCGGCAACAA
GGCCGAACCGCACGGCATCAACGTGGAAGGTCTGCGCCGCCGCGGCTTCTCGCCGGACGCGATCTCGGCGTTGCGCGCGG
CTTATCGCGTGCTGTACAAGAACGGCCTGTCGCTGGAAGAGGCGAAGGTGCAGCTGCGTGAACTCGCGTCCGCCGGCGGC
GACGGTGACGAACCGGTGCAGACACTGCTCGCGTTCGTCGAAGCGTCGCAACGCGGCATCATCCGCTAA

Upstream 100 bases:

>100_bases
GCTTGAGCTAGCGTCCCGGCGCTCAGCGGCGCGACGCGTGCGCTGAGCGCCCCGCCAGATGCCCACCCAGACAACGCAAC
AGAATCAGAAGCGAGGACGC

Downstream 100 bases:

>100_bases
CCGATGGCATTGCAACCTAGTCCACTGCGAGTGGCGATGGTGGCCGGCGAGCCGTCCGGCGACCTGCTGGCGGCGTCGCT
GCTCGACGGCCTCGCGAGCC

Product: UDP-N-acetylglucosamine acyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine acyltransferase [H]

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MSRIHPTAIVEPGAQLDESVEVGPYAVIGAHVTIGARTTVGSHSVIEGHTTLGEDNRIGHYASVGGRPQDMKYKDEPTRL
VIGSRNTIREFTTIHTGTVQDSGVTTLGDDNWIMAYVHIGHDCHVGNNVILSSNAQMAGHVIIGDHAIVGGMSGVHQFVR
IGAHSMLGGASALVQDIPPFVIAAGNKAEPHGINVEGLRRRGFSPDAISALRAAYRVLYKNGLSLEEAKVQLRELASAGG
DGDEPVQTLLAFVEASQRGIIR

Sequences:

>Translated_262_residues
MSRIHPTAIVEPGAQLDESVEVGPYAVIGAHVTIGARTTVGSHSVIEGHTTLGEDNRIGHYASVGGRPQDMKYKDEPTRL
VIGSRNTIREFTTIHTGTVQDSGVTTLGDDNWIMAYVHIGHDCHVGNNVILSSNAQMAGHVIIGDHAIVGGMSGVHQFVR
IGAHSMLGGASALVQDIPPFVIAAGNKAEPHGINVEGLRRRGFSPDAISALRAAYRVLYKNGLSLEEAKVQLRELASAGG
DGDEPVQTLLAFVEASQRGIIR
>Mature_261_residues
SRIHPTAIVEPGAQLDESVEVGPYAVIGAHVTIGARTTVGSHSVIEGHTTLGEDNRIGHYASVGGRPQDMKYKDEPTRLV
IGSRNTIREFTTIHTGTVQDSGVTTLGDDNWIMAYVHIGHDCHVGNNVILSSNAQMAGHVIIGDHAIVGGMSGVHQFVRI
GAHSMLGGASALVQDIPPFVIAAGNKAEPHGINVEGLRRRGFSPDAISALRAAYRVLYKNGLSLEEAKVQLRELASAGGD
GDEPVQTLLAFVEASQRGIIR

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG1043

COG function: function code M; Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786378, Length=259, Percent_Identity=51.7374517374517, Blast_Score=278, Evalue=3e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR010137
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.129 [H]

Molecular weight: Translated: 27760; Mature: 27629

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRIHPTAIVEPGAQLDESVEVGPYAVIGAHVTIGARTTVGSHSVIEGHTTLGEDNRIGH
CCCCCCCEEECCCCCCCCCCCCCCEEEEEEEEEECCEEECCCCCEEECCCCCCCCCCCCC
YASVGGRPQDMKYKDEPTRLVIGSRNTIREFTTIHTGTVQDSGVTTLGDDNWIMAYVHIG
CCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHEEECCCCCCCCCEEECCCCEEEEEEEEC
HDCHVGNNVILSSNAQMAGHVIIGDHAIVGGMSGVHQFVRIGAHSMLGGASALVQDIPPF
CEEECCCEEEEECCCCEEEEEEECCCCEECCHHHHHHHHHHHHHHHHCHHHHHHHHCCCE
VIAAGNKAEPHGINVEGLRRRGFSPDAISALRAAYRVLYKNGLSLEEAKVQLRELASAGG
EEECCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
DGDEPVQTLLAFVEASQRGIIR
CCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SRIHPTAIVEPGAQLDESVEVGPYAVIGAHVTIGARTTVGSHSVIEGHTTLGEDNRIGH
CCCCCCEEECCCCCCCCCCCCCCEEEEEEEEEECCEEECCCCCEEECCCCCCCCCCCCC
YASVGGRPQDMKYKDEPTRLVIGSRNTIREFTTIHTGTVQDSGVTTLGDDNWIMAYVHIG
CCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHEEECCCCCCCCCEEECCCCEEEEEEEEC
HDCHVGNNVILSSNAQMAGHVIIGDHAIVGGMSGVHQFVRIGAHSMLGGASALVQDIPPF
CEEECCCEEEEECCCCEEEEEEECCCCEECCHHHHHHHHHHHHHHHHCHHHHHHHHCCCE
VIAAGNKAEPHGINVEGLRRRGFSPDAISALRAAYRVLYKNGLSLEEAKVQLRELASAGG
EEECCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
DGDEPVQTLLAFVEASQRGIIR
CCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA