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The map label for this gene is lpxB [H]

Identifier: 91784106

GI number: 91784106

Start: 3032608

End: 3033777

Strand: Reverse

Name: lpxB [H]

Synonym: Bxe_A1695

Alternate gene names: 91784106

Gene position: 3033777-3032608 (Counterclockwise)

Preceding gene: 91784107

Following gene: 91784105

Centisome position: 61.97

GC content: 66.07

Gene sequence:

>1170_bases
ATGGCATTGCAACCTAGTCCACTGCGAGTGGCGATGGTGGCCGGCGAGCCGTCCGGCGACCTGCTGGCGGCGTCGCTGCT
CGACGGCCTCGCGAGCCGTTTGCCGGCCGGCACCCAATACTATGGGATCGGCGGTCCGCGCATGATCGCCACGGGCTTCG
ACGCCCACTTTCCGATGGAAAAGCTCACGGTGCGCGGCTATGTCGAAGCGCTGAAGCACATTCCTGAAATCCTTGGCATC
CGCACCGAACTGAAGCGCCAGTTGCTGGCCGAGCCGCCCTCGGTGTTCGTGGGCGTGGATGCGCCCGATTTCAACTTCGG
GCTCGAGCATCCGTTGCGCGACGCGGGGATTCCGACCGTTCACTTCGTGTGCCCGTCCATCTGGGCGTGGCGCGGCGGGC
GCATCAAGAAGATCGCCAAGGCGGTCGACCACATGCTGTGCGTGTTCCCGTTCGAAACGGCGCTGCTGGAAAAGGCGGGC
GTCGCGGCATCGTACGTCGGCCATCCGCTTGCCGATGAGATTCCGCTCGTACCGGACACGCTCGGCGCGCGCCGGGCGCT
GGGTCTCGCGGAAGAGGGCCCGATCATCGCGGTGCTGCCGGGCAGCCGGCGCTCGGAAATCGATCTGATCGGCCCGACGT
TCTTCGCCGCGATCGAGATGATGCAGCACCAGGAGCCCGCTCTGCGCTTCGTAATGCCGGCGGCCACGCCGGCACTGCGC
GAGATGCTGCGGCCGCTGGTGGATTCGCACCCCGGTCTCGCGCTGACGATTACCGACGGTCAGTCGCAACTCGCCATGAC
CGCGGCCGACGCGATCCTCGTAAAGAGCGGCACCGTGACGCTGGAAGCCGCACTGCTGAAAAAGCCGATGGTGATCTCGT
ACAAGGTGCCGTGGCTGACCGGCCAGATCATGCGCCGCCAGGGCTATCTGCCCTATGTCGGGTTGCCGAATATCCTGGCG
GGGCGCTTCGTGGTGCCCGAGATCCTGCAGCACTTCGCCACGCCCCAGGCGCTGGCCGAAGCCACGCTGAAACAGTTGCG
CGACGAGAACAACCGGCGCACGCTGACGGAAATCTTCACGGAGATGCATCACGTGCTGAAGCAGAACACCGCGCAGCGCG
CGGCGGAAGTCGTGGCGAGCGTCATCGAAAAGCGGAAGGCGCGGCCGTGA

Upstream 100 bases:

>100_bases
GCTGCGTGAACTCGCGTCCGCCGGCGGCGACGGTGACGAACCGGTGCAGACACTGCTCGCGTTCGTCGAAGCGTCGCAAC
GCGGCATCATCCGCTAACCG

Downstream 100 bases:

>100_bases
CCAGCGCACGCACGCCTCGCCGCAAGACCGTTGCAGGAGCGTCGGCGCAGCAGGTCGGCCTGAACTTCGAGACGCCGGAC
GACATTGTCTGCGGCGTCGA

Product: lipid-A-disaccharide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MALQPSPLRVAMVAGEPSGDLLAASLLDGLASRLPAGTQYYGIGGPRMIATGFDAHFPMEKLTVRGYVEALKHIPEILGI
RTELKRQLLAEPPSVFVGVDAPDFNFGLEHPLRDAGIPTVHFVCPSIWAWRGGRIKKIAKAVDHMLCVFPFETALLEKAG
VAASYVGHPLADEIPLVPDTLGARRALGLAEEGPIIAVLPGSRRSEIDLIGPTFFAAIEMMQHQEPALRFVMPAATPALR
EMLRPLVDSHPGLALTITDGQSQLAMTAADAILVKSGTVTLEAALLKKPMVISYKVPWLTGQIMRRQGYLPYVGLPNILA
GRFVVPEILQHFATPQALAEATLKQLRDENNRRTLTEIFTEMHHVLKQNTAQRAAEVVASVIEKRKARP

Sequences:

>Translated_389_residues
MALQPSPLRVAMVAGEPSGDLLAASLLDGLASRLPAGTQYYGIGGPRMIATGFDAHFPMEKLTVRGYVEALKHIPEILGI
RTELKRQLLAEPPSVFVGVDAPDFNFGLEHPLRDAGIPTVHFVCPSIWAWRGGRIKKIAKAVDHMLCVFPFETALLEKAG
VAASYVGHPLADEIPLVPDTLGARRALGLAEEGPIIAVLPGSRRSEIDLIGPTFFAAIEMMQHQEPALRFVMPAATPALR
EMLRPLVDSHPGLALTITDGQSQLAMTAADAILVKSGTVTLEAALLKKPMVISYKVPWLTGQIMRRQGYLPYVGLPNILA
GRFVVPEILQHFATPQALAEATLKQLRDENNRRTLTEIFTEMHHVLKQNTAQRAAEVVASVIEKRKARP
>Mature_388_residues
ALQPSPLRVAMVAGEPSGDLLAASLLDGLASRLPAGTQYYGIGGPRMIATGFDAHFPMEKLTVRGYVEALKHIPEILGIR
TELKRQLLAEPPSVFVGVDAPDFNFGLEHPLRDAGIPTVHFVCPSIWAWRGGRIKKIAKAVDHMLCVFPFETALLEKAGV
AASYVGHPLADEIPLVPDTLGARRALGLAEEGPIIAVLPGSRRSEIDLIGPTFFAAIEMMQHQEPALRFVMPAATPALRE
MLRPLVDSHPGLALTITDGQSQLAMTAADAILVKSGTVTLEAALLKKPMVISYKVPWLTGQIMRRQGYLPYVGLPNILAG
RFVVPEILQHFATPQALAEATLKQLRDENNRRTLTEIFTEMHHVLKQNTAQRAAEVVASVIEKRKARP

Specific function: Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG0763

COG function: function code M; Lipid A disaccharide synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxB family [H]

Homologues:

Organism=Escherichia coli, GI1786379, Length=376, Percent_Identity=39.6276595744681, Blast_Score=276, Evalue=2e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003835 [H]

Pfam domain/function: PF02684 LpxB [H]

EC number: =2.4.1.182 [H]

Molecular weight: Translated: 42315; Mature: 42184

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALQPSPLRVAMVAGEPSGDLLAASLLDGLASRLPAGTQYYGIGGPRMIATGFDAHFPME
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEECCCCCCCHH
KLTVRGYVEALKHIPEILGIRTELKRQLLAEPPSVFVGVDAPDFNFGLEHPLRDAGIPTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHCCCCEE
HFVCPSIWAWRGGRIKKIAKAVDHMLCVFPFETALLEKAGVAASYVGHPLADEIPLVPDT
EECCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCC
LGARRALGLAEEGPIIAVLPGSRRSEIDLIGPTFFAAIEMMQHQEPALRFVMPAATPALR
CCHHHHCCCCCCCCEEEEECCCCCCCEEEECHHHHHHHHHHHCCCCHHEEEECCCCHHHH
EMLRPLVDSHPGLALTITDGQSQLAMTAADAILVKSGTVTLEAALLKKPMVISYKVPWLT
HHHHHHHCCCCCEEEEEECCCCHHHHHHHHEEEEECCCEEEEHHHHCCCEEEEEECCHHH
GQIMRRQGYLPYVGLPNILAGRFVVPEILQHFATPQALAEATLKQLRDENNRRTLTEIFT
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHH
EMHHVLKQNTAQRAAEVVASVIEKRKARP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ALQPSPLRVAMVAGEPSGDLLAASLLDGLASRLPAGTQYYGIGGPRMIATGFDAHFPME
CCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEECCCCCCCHH
KLTVRGYVEALKHIPEILGIRTELKRQLLAEPPSVFVGVDAPDFNFGLEHPLRDAGIPTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHCCCCEE
HFVCPSIWAWRGGRIKKIAKAVDHMLCVFPFETALLEKAGVAASYVGHPLADEIPLVPDT
EECCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCC
LGARRALGLAEEGPIIAVLPGSRRSEIDLIGPTFFAAIEMMQHQEPALRFVMPAATPALR
CCHHHHCCCCCCCCEEEEECCCCCCCEEEECHHHHHHHHHHHCCCCHHEEEECCCCHHHH
EMLRPLVDSHPGLALTITDGQSQLAMTAADAILVKSGTVTLEAALLKKPMVISYKVPWLT
HHHHHHHCCCCCEEEEEECCCCHHHHHHHHEEEEECCCEEEEHHHHCCCEEEEEECCHHH
GQIMRRQGYLPYVGLPNILAGRFVVPEILQHFATPQALAEATLKQLRDENNRRTLTEIFT
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHH
EMHHVLKQNTAQRAAEVVASVIEKRKARP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA