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The map label for this gene is pcoR [H]

Identifier: 91784077

GI number: 91784077

Start: 3001666

End: 3002379

Strand: Reverse

Name: pcoR [H]

Synonym: Bxe_A1725

Alternate gene names: 91784077

Gene position: 3002379-3001666 (Counterclockwise)

Preceding gene: 91784078

Following gene: 91784076

Centisome position: 61.33

GC content: 63.17

Gene sequence:

>714_bases
ATGTCACGGGTTGCAATTGTCGAAGATCACGAACGCCTTGCCGACATGGTGGGCCAGGCCCTCGCCGGGGTGGGAGTCGA
GGCGGACGTTTTCCGCAATATCTCGGAGGCGACCTATGGCGTGAGCCGGGCCGACTACGCGGTGTTGATTGTCGATCGTG
GTCTTCCTGATGGCGATGGGCTGACTTTCCTGCGTGAGTTGCGTGCGGCGGGCCGGATGACGCCATGCTTGATGCTCACG
GCCCGCGATGCCTTGCACGATCGAGTCGACGGCTTGGAAAGCGGCGCGGACGACTACGTGACCAAGCCGTTTGCAATGAG
CGAGCTGGTCGCGCGGGTGCGCACCCTGATGCGCCGCCCGGTGACGCTGACAACGTTGGTTGCGTCATACGCGGATGTGG
TCGTGGATCCCCGCCAACGCGAGATGCGCTGCGGCGTGCTATCGGTTCTGCTTGCCCCGGCCGAACTACAGATCATGCTT
TGCCTTGTCGAGGCGGGTGGCCGAACTGTTCGGCATTTGGCACTCGAGCATGCCGCGTGGGGGCTTGGCGAAGCAGTAAC
ACCGAATGCGCTGGATGTGACCGTGCACCGGTTGCGGAAGAAACTTCTCGCGATCAACGCAAGGGCGCGACTGACGAATC
TTCGCGGCGCAGGATTTGCCCTGGAGGACGCTACGGCGCAACGGCAGCAGCCTTCGCGACCCGAAGGCACATGA

Upstream 100 bases:

>100_bases
CATTTTGGCGGCGGCATCACGGACAGTCCGCTTGTCGGGAAGAGATACGTCCCGGATATAAGGATCGGTTACACCTATCA
GTTCAAGTGAGCATAGTGTC

Downstream 100 bases:

>100_bases
GGGACCCGTTCTGCGGCCATCGGACCGCAAGAGCGACCGATTCGTGTCGCCCGCGGATCCACCCGATATGAGTATTCCGA
CGCCCAGCAATTCCGCTCCC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MSRVAIVEDHERLADMVGQALAGVGVEADVFRNISEATYGVSRADYAVLIVDRGLPDGDGLTFLRELRAAGRMTPCLMLT
ARDALHDRVDGLESGADDYVTKPFAMSELVARVRTLMRRPVTLTTLVASYADVVVDPRQREMRCGVLSVLLAPAELQIML
CLVEAGGRTVRHLALEHAAWGLGEAVTPNALDVTVHRLRKKLLAINARARLTNLRGAGFALEDATAQRQQPSRPEGT

Sequences:

>Translated_237_residues
MSRVAIVEDHERLADMVGQALAGVGVEADVFRNISEATYGVSRADYAVLIVDRGLPDGDGLTFLRELRAAGRMTPCLMLT
ARDALHDRVDGLESGADDYVTKPFAMSELVARVRTLMRRPVTLTTLVASYADVVVDPRQREMRCGVLSVLLAPAELQIML
CLVEAGGRTVRHLALEHAAWGLGEAVTPNALDVTVHRLRKKLLAINARARLTNLRGAGFALEDATAQRQQPSRPEGT
>Mature_236_residues
SRVAIVEDHERLADMVGQALAGVGVEADVFRNISEATYGVSRADYAVLIVDRGLPDGDGLTFLRELRAAGRMTPCLMLTA
RDALHDRVDGLESGADDYVTKPFAMSELVARVRTLMRRPVTLTTLVASYADVVVDPRQREMRCGVLSVLLAPAELQIMLC
LVEAGGRTVRHLALEHAAWGLGEAVTPNALDVTVHRLRKKLLAINARARLTNLRGAGFALEDATAQRQQPSRPEGT

Specific function: Probable member of a two-component regulatory system pcoS/pcoR. May be involved in the activation of copper resistance gene operon pcoABCD by binding to a specific site on the cop operon promoter (copper box) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=200, Percent_Identity=36.5, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=35.4545454545455, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI87082012, Length=219, Percent_Identity=31.9634703196347, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=32.3008849557522, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI1790552, Length=219, Percent_Identity=32.4200913242009, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1786911, Length=212, Percent_Identity=32.0754716981132, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1786599, Length=221, Percent_Identity=30.316742081448, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=32.579185520362, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=29.3333333333333, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=26.431718061674, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI2367329, Length=186, Percent_Identity=32.7956989247312, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790863, Length=221, Percent_Identity=30.7692307692308, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=25.4310344827586, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1790299, Length=110, Percent_Identity=32.7272727272727, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=32.1100917431193, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR006291
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25751; Mature: 25620

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRVAIVEDHERLADMVGQALAGVGVEADVFRNISEATYGVSRADYAVLIVDRGLPDGDG
CCCEEEECHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCH
LTFLRELRAAGRMTPCLMLTARDALHDRVDGLESGADDYVTKPFAMSELVARVRTLMRRP
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHCC
VTLTTLVASYADVVVDPRQREMRCGVLSVLLAPAELQIMLCLVEAGGRTVRHLALEHAAW
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHEEECCCCHHHHHHHHHHHHH
GLGEAVTPNALDVTVHRLRKKLLAINARARLTNLRGAGFALEDATAQRQQPSRPEGT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHCCCCCCCCC
>Mature Secondary Structure 
SRVAIVEDHERLADMVGQALAGVGVEADVFRNISEATYGVSRADYAVLIVDRGLPDGDG
CCEEEECHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCH
LTFLRELRAAGRMTPCLMLTARDALHDRVDGLESGADDYVTKPFAMSELVARVRTLMRRP
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHCC
VTLTTLVASYADVVVDPRQREMRCGVLSVLLAPAELQIMLCLVEAGGRTVRHLALEHAAW
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHEEECCCCHHHHHHHHHHHHH
GLGEAVTPNALDVTVHRLRKKLLAINARARLTNLRGAGFALEDATAQRQQPSRPEGT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8594334; 9141682 [H]