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The map label for this gene is adhA [H]

Identifier: 91783940

GI number: 91783940

Start: 2852864

End: 2853889

Strand: Direct

Name: adhA [H]

Synonym: Bxe_A1872

Alternate gene names: 91783940

Gene position: 2852864-2853889 (Clockwise)

Preceding gene: 91783937

Following gene: 91783944

Centisome position: 58.27

GC content: 63.65

Gene sequence:

>1026_bases
ATGGCCCAACTAATGAAAGCTGCTGTCGTTCACGAATTCGGCGCTCCGCTGCGTATCGAAGAGGTTCCCGTCCCGCAGGT
GGGGCGCGGCCAGATTCTGGTGAACATCAAGGCGTCCGGCGTCTGTCACACGGACCTGCACGCGGCCGACGGCGACTGGC
CGGTCAAGCCCACCCTGCCCTTCATTCCCGGTCACGAAGGCGTGGGCTATGTCGCTGCCGTCGGCGAAGGTGTCAAGCAT
GTCAAGGAAGGCGATCGCGTCGGCGTGCCGTGGCTTTATACCGCCTGCGGTCACTGCGAGCATTGCCTGGGCGGTTGGGA
AACGCTGTGCCAGGAACAGCAGAATACGGGCTACTCGGTCAACGGCGCTTACGCCGAATACGTGGTGGCCGACCCGAACT
TCGTCGGTCATCTGCCCGCGGCCGTCTCGTTCGAAGATATCGCCCCGATTCTGTGCGCGGGCGTGACGGTGTACAAAGGC
ATCCGCATGACGGACGCGCGGCCGGGTCAATGGATCACGATTTCGGGGATCGGCGGCCTCGGCCATGTCGCGGTTCAATA
TGCCATTGCGATGGGCCTGCGCGTGGTGGCCGTCGATATCTCGGAGGACAAGCTGGCTCTTGCCCGCGAACTCGGCGCAA
CGCTTGCGTTCAACGCTTCGGAGTGCGACCCCGCGGCGGCGATCCAGAAGGAAATCGGCGGAACGCACGGCGTGCTCGTC
ACCGCCGTATCGCGCAGCGCCTTCGCTCAGGCGCTGGGCATGGTGCGCCGCGGCGGCACCGTTGCGCTGAACGGTCTGCC
GCCGGGCGACTTTCCGCTGCCGATCTTCTCGACCGTGCTCAACGGCATTACCGTGCGCGGCTCCATTGTCGGCACGCGCC
AGGACTTGCAGGAATCACTCGAATTCGCCGCACAGGGCCGTGTGCGTGCCCGAATCCATCTCGACCGGCTGGACAATATC
AACCATGTTCTCGCCGAATTGAAGAGCGGGAAAGTGGATGGACGCATCGTTCTGAATCTCGATTGA

Upstream 100 bases:

>100_bases
AATGAAGAAGCGCGCATGGGTCCTGGATGACCCAGGTCAACCGCCCCGTATCGGTGAAGGAGATACTGGTCGCCACGTCA
TCAACGTCCGGAGAAAAGTT

Downstream 100 bases:

>100_bases
GCAAGCGGGCGAGCGGCAGAGTCGACGAAAGAGAAAGCGGCGCGAGCGCCTGAGCGGCTCGCGCCTTTTTCGTTTGAGGC
CTCTTCCCATGACGTTCTGG

Product: zinc-containing alcohol dehydrogenase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MAQLMKAAVVHEFGAPLRIEEVPVPQVGRGQILVNIKASGVCHTDLHAADGDWPVKPTLPFIPGHEGVGYVAAVGEGVKH
VKEGDRVGVPWLYTACGHCEHCLGGWETLCQEQQNTGYSVNGAYAEYVVADPNFVGHLPAAVSFEDIAPILCAGVTVYKG
IRMTDARPGQWITISGIGGLGHVAVQYAIAMGLRVVAVDISEDKLALARELGATLAFNASECDPAAAIQKEIGGTHGVLV
TAVSRSAFAQALGMVRRGGTVALNGLPPGDFPLPIFSTVLNGITVRGSIVGTRQDLQESLEFAAQGRVRARIHLDRLDNI
NHVLAELKSGKVDGRIVLNLD

Sequences:

>Translated_341_residues
MAQLMKAAVVHEFGAPLRIEEVPVPQVGRGQILVNIKASGVCHTDLHAADGDWPVKPTLPFIPGHEGVGYVAAVGEGVKH
VKEGDRVGVPWLYTACGHCEHCLGGWETLCQEQQNTGYSVNGAYAEYVVADPNFVGHLPAAVSFEDIAPILCAGVTVYKG
IRMTDARPGQWITISGIGGLGHVAVQYAIAMGLRVVAVDISEDKLALARELGATLAFNASECDPAAAIQKEIGGTHGVLV
TAVSRSAFAQALGMVRRGGTVALNGLPPGDFPLPIFSTVLNGITVRGSIVGTRQDLQESLEFAAQGRVRARIHLDRLDNI
NHVLAELKSGKVDGRIVLNLD
>Mature_340_residues
AQLMKAAVVHEFGAPLRIEEVPVPQVGRGQILVNIKASGVCHTDLHAADGDWPVKPTLPFIPGHEGVGYVAAVGEGVKHV
KEGDRVGVPWLYTACGHCEHCLGGWETLCQEQQNTGYSVNGAYAEYVVADPNFVGHLPAAVSFEDIAPILCAGVTVYKGI
RMTDARPGQWITISGIGGLGHVAVQYAIAMGLRVVAVDISEDKLALARELGATLAFNASECDPAAAIQKEIGGTHGVLVT
AVSRSAFAQALGMVRRGGTVALNGLPPGDFPLPIFSTVLNGITVRGSIVGTRQDLQESLEFAAQGRVRARIHLDRLDNIN
HVLAELKSGKVDGRIVLNLD

Specific function: Preferred Specificity Is Towards 1-Propanol. [C]

COG id: COG1064

COG function: function code R; Zn-dependent alcohol dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501933, Length=361, Percent_Identity=30.7479224376731, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI34577061, Length=347, Percent_Identity=31.4121037463977, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI4501929, Length=347, Percent_Identity=31.4121037463977, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI71565154, Length=239, Percent_Identity=32.2175732217573, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI156523966, Length=369, Percent_Identity=27.3712737127371, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI4501939, Length=362, Percent_Identity=27.3480662983425, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI71743840, Length=350, Percent_Identity=28.2857142857143, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI262073058, Length=350, Percent_Identity=28.2857142857143, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI71565152, Length=367, Percent_Identity=26.9754768392371, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI194239674, Length=271, Percent_Identity=27.3062730627306, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI13236495, Length=271, Percent_Identity=27.3062730627306, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI194239676, Length=228, Percent_Identity=28.9473684210526, Blast_Score=83, Evalue=4e-16,
Organism=Escherichia coli, GI87081918, Length=337, Percent_Identity=43.9169139465875, Blast_Score=252, Evalue=3e-68,
Organism=Escherichia coli, GI1786518, Length=345, Percent_Identity=32.1739130434783, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1790045, Length=335, Percent_Identity=30.1492537313433, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI87082401, Length=341, Percent_Identity=29.3255131964809, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI87082125, Length=204, Percent_Identity=35.7843137254902, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1788073, Length=269, Percent_Identity=33.0855018587361, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1788407, Length=217, Percent_Identity=34.1013824884793, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788075, Length=275, Percent_Identity=32, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1786552, Length=243, Percent_Identity=35.8024691358025, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI226510992, Length=299, Percent_Identity=28.0936454849498, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1790485, Length=292, Percent_Identity=28.4246575342466, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1787863, Length=281, Percent_Identity=27.7580071174377, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1786825, Length=304, Percent_Identity=26.6447368421053, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1790718, Length=318, Percent_Identity=22.9559748427673, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562584, Length=339, Percent_Identity=39.5280235988201, Blast_Score=223, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI71988145, Length=340, Percent_Identity=34.1176470588235, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI17562582, Length=340, Percent_Identity=38.8235294117647, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI17562876, Length=318, Percent_Identity=31.4465408805031, Blast_Score=121, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17562878, Length=225, Percent_Identity=36.4444444444444, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17507255, Length=265, Percent_Identity=30.5660377358491, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI25146526, Length=237, Percent_Identity=32.0675105485232, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71997431, Length=239, Percent_Identity=31.7991631799163, Blast_Score=88, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17565904, Length=210, Percent_Identity=30.4761904761905, Blast_Score=75, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6319621, Length=342, Percent_Identity=40.0584795321637, Blast_Score=258, Evalue=8e-70,
Organism=Saccharomyces cerevisiae, GI6323961, Length=343, Percent_Identity=39.3586005830904, Blast_Score=249, Evalue=4e-67,
Organism=Saccharomyces cerevisiae, GI6323729, Length=343, Percent_Identity=38.1924198250729, Blast_Score=248, Evalue=9e-67,
Organism=Saccharomyces cerevisiae, GI6324486, Length=341, Percent_Identity=39.0029325513196, Blast_Score=247, Evalue=2e-66,
Organism=Saccharomyces cerevisiae, GI6319949, Length=349, Percent_Identity=27.5071633237822, Blast_Score=102, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6322619, Length=330, Percent_Identity=28.1818181818182, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6319955, Length=330, Percent_Identity=28.1818181818182, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6320033, Length=242, Percent_Identity=31.8181818181818, Blast_Score=89, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6323099, Length=322, Percent_Identity=25.776397515528, Blast_Score=87, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6323980, Length=306, Percent_Identity=25.8169934640523, Blast_Score=83, Evalue=7e-17,
Organism=Drosophila melanogaster, GI17137530, Length=328, Percent_Identity=28.9634146341463, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI17737897, Length=310, Percent_Identity=28.0645161290323, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17737895, Length=248, Percent_Identity=28.6290322580645, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 36011; Mature: 35880

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQLMKAAVVHEFGAPLRIEEVPVPQVGRGQILVNIKASGVCHTDLHAADGDWPVKPTLP
CHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEEECCCEEECCCCCCCCCCCCCCCCC
FIPGHEGVGYVAAVGEGVKHVKEGDRVGVPWLYTACGHCEHCLGGWETLCQEQQNTGYSV
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCEE
NGAYAEYVVADPNFVGHLPAAVSFEDIAPILCAGVTVYKGIRMTDARPGQWITISGIGGL
CCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEECCCCCCCEEEEECCCCH
GHVAVQYAIAMGLRVVAVDISEDKLALARELGATLAFNASECDPAAAIQKEIGGTHGVLV
HHHHHHHHHHHCEEEEEEECCCCHHHHHHHHCCEEEECCCCCCHHHHHHHHHCCCCCEEE
TAVSRSAFAQALGMVRRGGTVALNGLPPGDFPLPIFSTVLNGITVRGSIVGTRQDLQESL
EEHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHCCEEEEEEEECCHHHHHHHH
EFAAQGRVRARIHLDRLDNINHVLAELKSGKVDGRIVLNLD
HHHHCCCEEEEEEECHHCCHHHHHHHHHCCCCCCEEEEEEC
>Mature Secondary Structure 
AQLMKAAVVHEFGAPLRIEEVPVPQVGRGQILVNIKASGVCHTDLHAADGDWPVKPTLP
HHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEEECCCEEECCCCCCCCCCCCCCCCC
FIPGHEGVGYVAAVGEGVKHVKEGDRVGVPWLYTACGHCEHCLGGWETLCQEQQNTGYSV
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCEE
NGAYAEYVVADPNFVGHLPAAVSFEDIAPILCAGVTVYKGIRMTDARPGQWITISGIGGL
CCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEECCCCCCCEEEEECCCCH
GHVAVQYAIAMGLRVVAVDISEDKLALARELGATLAFNASECDPAAAIQKEIGGTHGVLV
HHHHHHHHHHHCEEEEEEECCCCHHHHHHHHCCEEEECCCCCCHHHHHHHHHCCCCCEEE
TAVSRSAFAQALGMVRRGGTVALNGLPPGDFPLPIFSTVLNGITVRGSIVGTRQDLQESL
EEHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHCCEEEEEEEECCHHHHHHHH
EFAAQGRVRARIHLDRLDNINHVLAELKSGKVDGRIVLNLD
HHHHCCCEEEEEEECHHCCHHHHHHHHHCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9659380; 11481432 [H]