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The map label for this gene is lrhA [H]

Identifier: 91783790

GI number: 91783790

Start: 2692323

End: 2693183

Strand: Reverse

Name: lrhA [H]

Synonym: Bxe_A2022

Alternate gene names: 91783790

Gene position: 2693183-2692323 (Counterclockwise)

Preceding gene: 91783792

Following gene: 91783789

Centisome position: 55.01

GC content: 69.22

Gene sequence:

>861_bases
ATGCTCAATCCCATCTGGCTCAAGACCTTCTCGACCGTCGCGGCCTGCCACAGTTTCACCGAGGCAGGGCGGCGGCTCGG
CCTGACGCAATCGAGCGTCAGCGAACACATCCGGCGGCTCGAAGAAAGCGTGGGCCGCCGCCTCTTCGTGCGCGACACCC
ATTCGCTTGCCATGACGCCCGACGGCGAAGCCATGCTCGCGCATGCCAGCGTGATTCTGCAGGCGCTCGCGCGAGCCGAG
TCGCAGTTTCGCGCGCCGCGCCTGAAGGGCCGCGTGCGGCTCGGTTCCTCGGACGACGTCGCGCTCGGCCCGCTGCCCAC
CGTACTGGCCGCGTTTCGCAACGCGCATCCCGATGTCGAACTGGAAATCACCATCGGCATGACCGGCAAGCTGTATGAAC
TGCTCGACGCGGGCGCGATCGATCTGCTGGTCGGCAAGCGGCGTCTTGGCGACCGGCGCGGCGTGCCGCTTTTCACCGGG
CGGCTGGAGTGGCTCGCGCGCGCCGGCACACTGGTCGATCTGAGCCAGCCATTGCCGCTGATTCTCGTCGCCGAGCCGAG
CGTGACGCGGGCCGTCGTGCTCGACGCGCTCGCCGAGGCGGGTTTCCGCTGGCAGGTGGTGTGCACGAGCAGCAGTCACG
CCGGCTGCATCGCGGCGGCGCGCGGCGGGCTCGGCATCATGGTTCGTCCGCAGTATCTGGCCGCTCGGGGTCTGGCGGCG
CCGCTGAACGCGGCGAGTCTGCCGGCGTTGCCGTCGGTGGAATTCATCGCGCTGGCGGCGAAGCGGCTCAGCCGGCCGGC
GGGCACGCTGTTGAAGTTGCTGCATGACAGCGATCTGCGTGGGTCGTGGATCGGGGAGTGA

Upstream 100 bases:

>100_bases
GGGGAATTGCGTCATGATATTGACATCCTCGTCAATCGGGAACCCCACTAGGGGCGCTGATTGTCATCGACATTGCCGAT
AAGCAGCGCGAGAATAGCCG

Downstream 100 bases:

>100_bases
GCCAGCACACGTGAGCGTACGCAGCTAACAGAGCGCGGTAGGGCGCGGTCGGCATGGGGAACACCGCGCCGCGCTTCAGT
CACGCCACACGTGACGGCTT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MLNPIWLKTFSTVAACHSFTEAGRRLGLTQSSVSEHIRRLEESVGRRLFVRDTHSLAMTPDGEAMLAHASVILQALARAE
SQFRAPRLKGRVRLGSSDDVALGPLPTVLAAFRNAHPDVELEITIGMTGKLYELLDAGAIDLLVGKRRLGDRRGVPLFTG
RLEWLARAGTLVDLSQPLPLILVAEPSVTRAVVLDALAEAGFRWQVVCTSSSHAGCIAAARGGLGIMVRPQYLAARGLAA
PLNAASLPALPSVEFIALAAKRLSRPAGTLLKLLHDSDLRGSWIGE

Sequences:

>Translated_286_residues
MLNPIWLKTFSTVAACHSFTEAGRRLGLTQSSVSEHIRRLEESVGRRLFVRDTHSLAMTPDGEAMLAHASVILQALARAE
SQFRAPRLKGRVRLGSSDDVALGPLPTVLAAFRNAHPDVELEITIGMTGKLYELLDAGAIDLLVGKRRLGDRRGVPLFTG
RLEWLARAGTLVDLSQPLPLILVAEPSVTRAVVLDALAEAGFRWQVVCTSSSHAGCIAAARGGLGIMVRPQYLAARGLAA
PLNAASLPALPSVEFIALAAKRLSRPAGTLLKLLHDSDLRGSWIGE
>Mature_286_residues
MLNPIWLKTFSTVAACHSFTEAGRRLGLTQSSVSEHIRRLEESVGRRLFVRDTHSLAMTPDGEAMLAHASVILQALARAE
SQFRAPRLKGRVRLGSSDDVALGPLPTVLAAFRNAHPDVELEITIGMTGKLYELLDAGAIDLLVGKRRLGDRRGVPLFTG
RLEWLARAGTLVDLSQPLPLILVAEPSVTRAVVLDALAEAGFRWQVVCTSSSHAGCIAAARGGLGIMVRPQYLAARGLAA
PLNAASLPALPSVEFIALAAKRLSRPAGTLLKLLHDSDLRGSWIGE

Specific function: Not known, does not seem to act on the proton translocating NADH dehydrogenase genes (nuoA-N) which are part of the lrhA operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=250, Percent_Identity=30, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1790208, Length=143, Percent_Identity=31.4685314685315, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787601, Length=146, Percent_Identity=28.7671232876712, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1788748, Length=289, Percent_Identity=25.2595155709343, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787589, Length=136, Percent_Identity=33.0882352941176, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790262, Length=138, Percent_Identity=31.1594202898551, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788887, Length=160, Percent_Identity=31.875, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788296, Length=227, Percent_Identity=28.1938325991189, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787806, Length=161, Percent_Identity=26.0869565217391, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1786401, Length=187, Percent_Identity=29.4117647058824, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87081904, Length=142, Percent_Identity=31.6901408450704, Blast_Score=61, Evalue=9e-11,
Organism=Escherichia coli, GI1789173, Length=158, Percent_Identity=28.4810126582279, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 30640; Mature: 30640

Theoretical pI: Translated: 10.35; Mature: 10.35

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNPIWLKTFSTVAACHSFTEAGRRLGLTQSSVSEHIRRLEESVGRRLFVRDTHSLAMTP
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEEEECCCEEECC
DGEAMLAHASVILQALARAESQFRAPRLKGRVRLGSSDDVALGPLPTVLAAFRNAHPDVE
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEECCCHHHHHHHHHCCCCCEE
LEITIGMTGKLYELLDAGAIDLLVGKRRLGDRRGVPLFTGRLEWLARAGTLVDLSQPLPL
EEEEECCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEHHHHHHHHHCCCEEECCCCCCE
ILVAEPSVTRAVVLDALAEAGFRWQVVCTSSSHAGCIAAARGGLGIMVRPQYLAARGLAA
EEEECCCHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEECCCCEEEEECCHHHHHCCCCC
PLNAASLPALPSVEFIALAAKRLSRPAGTLLKLLHDSDLRGSWIGE
CCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MLNPIWLKTFSTVAACHSFTEAGRRLGLTQSSVSEHIRRLEESVGRRLFVRDTHSLAMTP
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEEEECCCEEECC
DGEAMLAHASVILQALARAESQFRAPRLKGRVRLGSSDDVALGPLPTVLAAFRNAHPDVE
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEECCCHHHHHHHHHCCCCCEE
LEITIGMTGKLYELLDAGAIDLLVGKRRLGDRRGVPLFTGRLEWLARAGTLVDLSQPLPL
EEEEECCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEHHHHHHHHHCCCEEECCCCCCE
ILVAEPSVTRAVVLDALAEAGFRWQVVCTSSSHAGCIAAARGGLGIMVRPQYLAARGLAA
EEEECCCHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEECCCCEEEEECCHHHHHCCCCC
PLNAASLPALPSVEFIALAAKRLSRPAGTLLKLLHDSDLRGSWIGE
CCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]