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The map label for this gene is nac [H]

Identifier: 91783744

GI number: 91783744

Start: 2643979

End: 2644965

Strand: Direct

Name: nac [H]

Synonym: Bxe_A2070

Alternate gene names: 91783744

Gene position: 2643979-2644965 (Clockwise)

Preceding gene: 91783735

Following gene: 91783748

Centisome position: 54.0

GC content: 65.45

Gene sequence:

>987_bases
ATGGACCTCAGGCAAATCCAGTATTTCATCGCGCTTTTCGAAGACGGTTCGGTCACGCGGGCAGCGAAACGCCTGAACAT
CGTGCAACCCGCGCTCAGCATGCAGATCGCCAAACTCGAGGACGAACTGCACCAGCAGCTATTCGAGCGCAACGCTCACG
GCATGGCGCCGACGGCGGCCGGCCGGCTCATGTACCGGCTCTTTCTGCCGATCATGCGCGACCTCGCGCACGCGCGCCAG
CAACTCGTGCAGCGCGACGAAGTGGTGACCGGCCATGTGTCGATCGGGCTGATTGCCTCGGTAACGGAGAGCGTGCTGGC
CGATGCGCTGTCACGCTTTCACGCGCGCTATCCGCATGTGGAGGTGACCGTGGCGGACGGCTACAGCGCGACATTCATCG
ACTGGGTGGCGGGCGGGCAACTCGACGCGGCCCTGATCAACAAGCCGCGCGCGCGCCTTTCGCTCGACTCGCAGCCCCTG
CTCGACGAGGAAATGGTGCTGGTGACGAGCGCCACGCACGGCCCGGAACTGCCGCATGCCATCGAACTCGCGCAACTGCC
CGAACTGGAACTGGTGCTGCCGACCAAGCGCCACGGCTTGCGCGGCGTGCTCGATACGGCTGCGCAGCATGAAGACGTGC
TGCTCGCGCCGCGCTTCGAGATCGACGTGTTGAGCACGATCGTGAAACTGGTGGAAAGCACGCACTTTGCGACCATCCTG
CCGCGCATCGCCGTGCAGCGCGCGGTGCGCCAGGGCACCCTGCGTGCCTATCCGATTCTCGCGCCGCGCATTGTGCGGCA
TATCGTGTGCGTGAGCCATCCGCGGCGCCCGTTGAGCGCGGCGGCGGATGCACTGGTGTCGATCATCGCCGACGAATTGC
GGCAGGTGTCGAGCGAGTCGGAGCTGGATGCGACCGTGACGGGCTCATCCGCCGATGCGCCGGGTGAATCGCGCTCAGCG
GCTGTTTCCAGAGAACGTTCTGCGTGA

Upstream 100 bases:

>100_bases
CGGCGCGCCGCGCCGAAGCGTTCGTGACGTGCGGTTCAGGCCTTCATCTGATACGGCGCGGCATGCTCATTACGTTTGCT
GATGTTTTATTGATTCCCAC

Downstream 100 bases:

>100_bases
ACGGCGGGTGTTTACGATCGCAAAGAAGATGGGCCAAAACTTTTCATATCATTCGGATACCCAGGCAGTTCTTGGCCGGT
CGGGTTCCTCTTCAGGGAGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Nitrogen assimilation control protein [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MDLRQIQYFIALFEDGSVTRAAKRLNIVQPALSMQIAKLEDELHQQLFERNAHGMAPTAAGRLMYRLFLPIMRDLAHARQ
QLVQRDEVVTGHVSIGLIASVTESVLADALSRFHARYPHVEVTVADGYSATFIDWVAGGQLDAALINKPRARLSLDSQPL
LDEEMVLVTSATHGPELPHAIELAQLPELELVLPTKRHGLRGVLDTAAQHEDVLLAPRFEIDVLSTIVKLVESTHFATIL
PRIAVQRAVRQGTLRAYPILAPRIVRHIVCVSHPRRPLSAAADALVSIIADELRQVSSESELDATVTGSSADAPGESRSA
AVSRERSA

Sequences:

>Translated_328_residues
MDLRQIQYFIALFEDGSVTRAAKRLNIVQPALSMQIAKLEDELHQQLFERNAHGMAPTAAGRLMYRLFLPIMRDLAHARQ
QLVQRDEVVTGHVSIGLIASVTESVLADALSRFHARYPHVEVTVADGYSATFIDWVAGGQLDAALINKPRARLSLDSQPL
LDEEMVLVTSATHGPELPHAIELAQLPELELVLPTKRHGLRGVLDTAAQHEDVLLAPRFEIDVLSTIVKLVESTHFATIL
PRIAVQRAVRQGTLRAYPILAPRIVRHIVCVSHPRRPLSAAADALVSIIADELRQVSSESELDATVTGSSADAPGESRSA
AVSRERSA
>Mature_328_residues
MDLRQIQYFIALFEDGSVTRAAKRLNIVQPALSMQIAKLEDELHQQLFERNAHGMAPTAAGRLMYRLFLPIMRDLAHARQ
QLVQRDEVVTGHVSIGLIASVTESVLADALSRFHARYPHVEVTVADGYSATFIDWVAGGQLDAALINKPRARLSLDSQPL
LDEEMVLVTSATHGPELPHAIELAQLPELELVLPTKRHGLRGVLDTAAQHEDVLLAPRFEIDVLSTIVKLVESTHFATIL
PRIAVQRAVRQGTLRAYPILAPRIVRHIVCVSHPRRPLSAAADALVSIIADELRQVSSESELDATVTGSSADAPGESRSA
AVSRERSA

Specific function: Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation. Negative regulator of its own expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788297, Length=246, Percent_Identity=28.8617886178862, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1790399, Length=293, Percent_Identity=27.3037542662116, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI157672245, Length=293, Percent_Identity=26.6211604095563, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1787601, Length=248, Percent_Identity=29.0322580645161, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI145693105, Length=300, Percent_Identity=25.6666666666667, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1787806, Length=175, Percent_Identity=32.5714285714286, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789506, Length=236, Percent_Identity=25.8474576271186, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788481, Length=287, Percent_Identity=25.4355400696864, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788887, Length=176, Percent_Identity=29.5454545454545, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788748, Length=308, Percent_Identity=21.4285714285714, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081904, Length=261, Percent_Identity=24.1379310344828, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790208, Length=149, Percent_Identity=29.5302013422819, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789639, Length=137, Percent_Identity=28.4671532846715, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI2367136, Length=148, Percent_Identity=30.4054054054054, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1787589, Length=263, Percent_Identity=23.574144486692, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787879, Length=265, Percent_Identity=28.3018867924528, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789204, Length=149, Percent_Identity=30.2013422818792, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35939; Mature: 35939

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLRQIQYFIALFEDGSVTRAAKRLNIVQPALSMQIAKLEDELHQQLFERNAHGMAPTAA
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
GRLMYRLFLPIMRDLAHARQQLVQRDEVVTGHVSIGLIASVTESVLADALSRFHARYPHV
HHHHHHHHHHHHHHHHHHHHHHHHHHCEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
EVTVADGYSATFIDWVAGGQLDAALINKPRARLSLDSQPLLDEEMVLVTSATHGPELPHA
EEEEECCCCCHHHHHHCCCCCCHHHHCCCCHHCCCCCCCCCCCCEEEEEECCCCCCCCCH
IELAQLPELELVLPTKRHGLRGVLDTAAQHEDVLLAPRFEIDVLSTIVKLVESTHFATIL
HHHHCCCCCEEECCCHHCCHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHCCHHHHHH
PRIAVQRAVRQGTLRAYPILAPRIVRHIVCVSHPRRPLSAAADALVSIIADELRQVSSES
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
ELDATVTGSSADAPGESRSAAVSRERSA
CCCEEEECCCCCCCCCCHHHHHHHCCCC
>Mature Secondary Structure
MDLRQIQYFIALFEDGSVTRAAKRLNIVQPALSMQIAKLEDELHQQLFERNAHGMAPTAA
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
GRLMYRLFLPIMRDLAHARQQLVQRDEVVTGHVSIGLIASVTESVLADALSRFHARYPHV
HHHHHHHHHHHHHHHHHHHHHHHHHHCEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
EVTVADGYSATFIDWVAGGQLDAALINKPRARLSLDSQPLLDEEMVLVTSATHGPELPHA
EEEEECCCCCHHHHHHCCCCCCHHHHCCCCHHCCCCCCCCCCCCEEEEEECCCCCCCCCH
IELAQLPELELVLPTKRHGLRGVLDTAAQHEDVLLAPRFEIDVLSTIVKLVESTHFATIL
HHHHCCCCCEEECCCHHCCHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHCCHHHHHH
PRIAVQRAVRQGTLRAYPILAPRIVRHIVCVSHPRRPLSAAADALVSIIADELRQVSSES
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
ELDATVTGSSADAPGESRSAAVSRERSA
CCCEEEECCCCCCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8458853 [H]