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The map label for this gene is tauD [C]

Identifier: 91783660

GI number: 91783660

Start: 2539000

End: 2539947

Strand: Direct

Name: tauD [C]

Synonym: Bxe_A2155

Alternate gene names: 91783660

Gene position: 2539000-2539947 (Clockwise)

Preceding gene: 91783659

Following gene: 91783661

Centisome position: 51.86

GC content: 65.72

Gene sequence:

>948_bases
ATGAGTGCAGCCGCAGTGCAGGAAATACAGTCGATCGAGGTCACGCCGCTTTCCGCGCATATCGGTGCGGAGATTCACGG
CGTCGATCTTACGCAGAAGCTGGAGGCGCGCCAGATCGCGGAGATTCGCGCGGCGCTTCTGAAGTGGCGCGTCGTATTCT
TTCGCGAGCAGTTCCTGACGCACGAGCAGCACGTCGCGTTCTCGGCGCAGTTCGGCGAACTGACCTTGGGGCACCCCGTG
TTCGGCCATGTGGAAGGGCATCCGGAGGTCTATTCGATCTCGAAGTACCGCAAGGCCACGCGCTTCGAGGGGCAAACGCT
GCAACGCCCGTGGACCGGCTGGCATACGGACGTCACGGCGGCGGTCAATCCGCCGTGGGCGTCGATCCTGCGCGGCGTGA
CGATTCCGCCGTACGGCGGCGACACGCAGTGGACCAACCTGGTGGCCGCGTATCAGAAGCTGTCGGCGCCGCTGCGTTCG
TTCGTCGACGGGCTGCGCGGGATTCACCGCTTTACGCCGCCGGCCGGCGCGAGCGGAACGCAGGCGTTTGTCGAAGCCGT
CGAGCAGCGCATTCTCGTCACCGAGCATCCCCTTGTCAGGGTTCATCCGGAAACGGGCGAGCGGGCGCTCTATGTGAGCC
CGAGCTTCCTGAAGTCGATCGTCGGCGTGAGTCCGCGCGAAAGCCAGGTGCTGCTCGAACTGCTGTGGGAACACGTGACG
CGGCCGGAGTTCACCGTGCGCTTCAAATGGCAGGCCGGCAGCGTCGCGTTCTGGGACAACCGGGCAACGGCGCACCTCGC
GCCCACGGATATTTTCGATCTCGACTTCGACCGGCAACTGTATCGCACCACGCTGGTCGGCGACGTGCCCGTCGGCCCGG
ACGGCACGCAATCGGTGGCGATCGAAGGCTCGCCGGTGAGCGCCGCCGCGGCCGTCGCATTGAACTGA

Upstream 100 bases:

>100_bases
CGCGACTGGAGCGCCACTAAAAGGCCGCTGAACGGCCAGTAAAGCGACGGCGTTCGCGCCGTCGGCCCCACCCGTTCTCT
TCGTCAGGAGCTTTTCATTC

Downstream 100 bases:

>100_bases
GCTGGGCACGCCCGCGTCCGGCATGAGCGCGCCAGGCTGACCAGACCATCCGTGTTCACTCGACTCGCCCCCCCGTCTGC
GGCTATCTTACGGACTGGGC

Product: putative alpha-ketoglutarate-dependent taurine dioxygenase

Products: Aminoacetaldehyde; CO2; H+; Sulfite; Succinate [C]

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MSAAAVQEIQSIEVTPLSAHIGAEIHGVDLTQKLEARQIAEIRAALLKWRVVFFREQFLTHEQHVAFSAQFGELTLGHPV
FGHVEGHPEVYSISKYRKATRFEGQTLQRPWTGWHTDVTAAVNPPWASILRGVTIPPYGGDTQWTNLVAAYQKLSAPLRS
FVDGLRGIHRFTPPAGASGTQAFVEAVEQRILVTEHPLVRVHPETGERALYVSPSFLKSIVGVSPRESQVLLELLWEHVT
RPEFTVRFKWQAGSVAFWDNRATAHLAPTDIFDLDFDRQLYRTTLVGDVPVGPDGTQSVAIEGSPVSAAAAVALN

Sequences:

>Translated_315_residues
MSAAAVQEIQSIEVTPLSAHIGAEIHGVDLTQKLEARQIAEIRAALLKWRVVFFREQFLTHEQHVAFSAQFGELTLGHPV
FGHVEGHPEVYSISKYRKATRFEGQTLQRPWTGWHTDVTAAVNPPWASILRGVTIPPYGGDTQWTNLVAAYQKLSAPLRS
FVDGLRGIHRFTPPAGASGTQAFVEAVEQRILVTEHPLVRVHPETGERALYVSPSFLKSIVGVSPRESQVLLELLWEHVT
RPEFTVRFKWQAGSVAFWDNRATAHLAPTDIFDLDFDRQLYRTTLVGDVPVGPDGTQSVAIEGSPVSAAAAVALN
>Mature_314_residues
SAAAVQEIQSIEVTPLSAHIGAEIHGVDLTQKLEARQIAEIRAALLKWRVVFFREQFLTHEQHVAFSAQFGELTLGHPVF
GHVEGHPEVYSISKYRKATRFEGQTLQRPWTGWHTDVTAAVNPPWASILRGVTIPPYGGDTQWTNLVAAYQKLSAPLRSF
VDGLRGIHRFTPPAGASGTQAFVEAVEQRILVTEHPLVRVHPETGERALYVSPSFLKSIVGVSPRESQVLLELLWEHVTR
PEFTVRFKWQAGSVAFWDNRATAHLAPTDIFDLDFDRQLYRTTLVGDVPVGPDGTQSVAIEGSPVSAAAAVALN

Specific function: Catalyzes The Conversion Of Taurine And Alpha Ketoglutarate To Sulfite, Aminoacetaldehyde And Succinate. Required For The Utilization Of Taurine (2-Aminoethanesulfonic Acid) As An Alternative Sulfur Source. Pentane-Sulfonic Acid, 3- (N-Morpholino)Propanes

COG id: COG2175

COG function: function code Q; Probable taurine catabolism dioxygenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tfdA dioxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786565, Length=288, Percent_Identity=39.5833333333333, Blast_Score=196, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6322971, Length=294, Percent_Identity=31.6326530612245, Blast_Score=124, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003819 [H]

Pfam domain/function: PF02668 TauD [H]

EC number: 1.14.11.17 [C]

Molecular weight: Translated: 34795; Mature: 34664

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAAAVQEIQSIEVTPLSAHIGAEIHGVDLTQKLEARQIAEIRAALLKWRVVFFREQFLT
CCHHHHHHHHHCCCEEEHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
HEQHVAFSAQFGELTLGHPVFGHVEGHPEVYSISKYRKATRFEGQTLQRPWTGWHTDVTA
HHHHEEEEECCCCEEECCCEEEEECCCCCEEEHHHHHHHHHCCCCCCCCCCCCCCCCEEE
AVNPPWASILRGVTIPPYGGDTQWTNLVAAYQKLSAPLRSFVDGLRGIHRFTPPAGASGT
ECCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
QAFVEAVEQRILVTEHPLVRVHPETGERALYVSPSFLKSIVGVSPRESQVLLELLWEHVT
HHHHHHHHHHEEEECCCEEEECCCCCCEEEEECHHHHHHHHCCCCCHHHHHHHHHHHHCC
RPEFTVRFKWQAGSVAFWDNRATAHLAPTDIFDLDFDRQLYRTTLVGDVPVGPDGTQSVA
CCCEEEEEEECCCCEEEECCCCEEEECCCCEEECCCCHHHHHHHEECCCCCCCCCCCEEE
IEGSPVSAAAAVALN
EECCCCCCEEEEECC
>Mature Secondary Structure 
SAAAVQEIQSIEVTPLSAHIGAEIHGVDLTQKLEARQIAEIRAALLKWRVVFFREQFLT
CHHHHHHHHHCCCEEEHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
HEQHVAFSAQFGELTLGHPVFGHVEGHPEVYSISKYRKATRFEGQTLQRPWTGWHTDVTA
HHHHEEEEECCCCEEECCCEEEEECCCCCEEEHHHHHHHHHCCCCCCCCCCCCCCCCEEE
AVNPPWASILRGVTIPPYGGDTQWTNLVAAYQKLSAPLRSFVDGLRGIHRFTPPAGASGT
ECCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
QAFVEAVEQRILVTEHPLVRVHPETGERALYVSPSFLKSIVGVSPRESQVLLELLWEHVT
HHHHHHHHHHEEEECCCEEEECCCCCCEEEEECHHHHHHHHCCCCCHHHHHHHHHHHHCC
RPEFTVRFKWQAGSVAFWDNRATAHLAPTDIFDLDFDRQLYRTTLVGDVPVGPDGTQSVA
CCCEEEEEEECCCCEEEECCCCEEEECCCCEEECCCCHHHHHHHEECCCCCCCCCCCEEE
IEGSPVSAAAAVALN
EECCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Ascorbate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; O2; Taurine [C]

Specific reaction: 2-Oxoglutarate + O2 + Taurine --> Aminoacetaldehyde + CO2 + H+ + Sulfite + Succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]