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The map label for this gene is tmk [H]

Identifier: 91783552

GI number: 91783552

Start: 2414075

End: 2414695

Strand: Direct

Name: tmk [H]

Synonym: Bxe_A2263

Alternate gene names: 91783552

Gene position: 2414075-2414695 (Clockwise)

Preceding gene: 91783551

Following gene: 91783553

Centisome position: 49.31

GC content: 64.9

Gene sequence:

>621_bases
ATGGCGCGGGGCAAATTCATCACGTTTGAGGGCATCGACGGGGCGGGCAAGACAACCCACCTCAGCTGGTTTCGGGAGCG
CCTCGAACAGAAAGTCGCGAGCACCGGGCGCTCGGTCGTCATGACGCGCGAACCGGGCGGCACGCCGCTCGGCGAGCAGA
TTCGCGAAATCGTGCTGCATCAGAAAATGGACCTCGAAACCGAGGCGCTGCTGATGTTCGCGCTGCGCCGCCAGCATCTG
GCCGAAGTGATCGAGCCGGCGCTCGCGCGCGGCGACTGGGTGCTGTCGGACCGTTTCACCGACGCGACCTTCGCCTATCA
GGGCGGCGGCCGCGGACTGCCGCGCGACAAGCTGGAAACCCTGGAGCGCTGGGTGCAGGGCGGCTTTCAACCGGACCTGA
CGGTGCTGTTCGACCTCGATCCCGAGGTCGCCAGCGAGCGGCGCAGCGCGGCGCGCGACCCGGATCGTTTCGAGAGCGAA
TCGGAGGCGTTCTTCAGCCGTACCCGCGCCGAATATCTGCGCCGTGCCGAAGAAGCGCCGTACCGGTTCGCTATCATTGA
CTCCGCGCAGAGCATCGCGCAGATTCAGAGGCGACTTGAAGAATTGATTGCAATTCTTTGA

Upstream 100 bases:

>100_bases
CCGCGCTGTACTTCGTTTCGCGCGGCGACGGCAGCAGTATCTTTTCCGACACCCTCGGCGATCACAACAAGGCCGTGGAC
AAATACATTCGAGGGCAATG

Downstream 100 bases:

>100_bases
TTTTAAAAGAATATAATTCTGGTTTATAACGGTTTGAAGAGTTCTTGCTATATCTCGGATAACGTCTTCAACCGATTGAT
TTTAAAGAGAAACGATGATT

Product: thymidylate kinase

Products: NA

Alternate protein names: dTMP kinase [H]

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MARGKFITFEGIDGAGKTTHLSWFRERLEQKVASTGRSVVMTREPGGTPLGEQIREIVLHQKMDLETEALLMFALRRQHL
AEVIEPALARGDWVLSDRFTDATFAYQGGGRGLPRDKLETLERWVQGGFQPDLTVLFDLDPEVASERRSAARDPDRFESE
SEAFFSRTRAEYLRRAEEAPYRFAIIDSAQSIAQIQRRLEELIAIL

Sequences:

>Translated_206_residues
MARGKFITFEGIDGAGKTTHLSWFRERLEQKVASTGRSVVMTREPGGTPLGEQIREIVLHQKMDLETEALLMFALRRQHL
AEVIEPALARGDWVLSDRFTDATFAYQGGGRGLPRDKLETLERWVQGGFQPDLTVLFDLDPEVASERRSAARDPDRFESE
SEAFFSRTRAEYLRRAEEAPYRFAIIDSAQSIAQIQRRLEELIAIL
>Mature_205_residues
ARGKFITFEGIDGAGKTTHLSWFRERLEQKVASTGRSVVMTREPGGTPLGEQIREIVLHQKMDLETEALLMFALRRQHLA
EVIEPALARGDWVLSDRFTDATFAYQGGGRGLPRDKLETLERWVQGGFQPDLTVLFDLDPEVASERRSAARDPDRFESES
EAFFSRTRAEYLRRAEEAPYRFAIIDSAQSIAQIQRRLEELIAIL

Specific function: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis [H]

COG id: COG0125

COG function: function code F; Thymidylate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidylate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1787340, Length=199, Percent_Identity=44.2211055276382, Blast_Score=144, Evalue=5e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018094 [H]

Pfam domain/function: PF02223 Thymidylate_kin [H]

EC number: =2.7.4.9 [H]

Molecular weight: Translated: 23471; Mature: 23340

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARGKFITFEGIDGAGKTTHLSWFRERLEQKVASTGRSVVMTREPGGTPLGEQIREIVLH
CCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHH
QKMDLETEALLMFALRRQHLAEVIEPALARGDWVLSDRFTDATFAYQGGGRGLPRDKLET
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCEEECCCCCCCCHHHHHH
LERWVQGGFQPDLTVLFDLDPEVASERRSAARDPDRFESESEAFFSRTRAEYLRRAEEAP
HHHHHHCCCCCCEEEEEECCHHHHHHHHHHCCCCHHHCHHHHHHHHHHHHHHHHHHHCCC
YRFAIIDSAQSIAQIQRRLEELIAIL
EEEEEHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ARGKFITFEGIDGAGKTTHLSWFRERLEQKVASTGRSVVMTREPGGTPLGEQIREIVLH
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHH
QKMDLETEALLMFALRRQHLAEVIEPALARGDWVLSDRFTDATFAYQGGGRGLPRDKLET
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCEEECCCCCCCCHHHHHH
LERWVQGGFQPDLTVLFDLDPEVASERRSAARDPDRFESESEAFFSRTRAEYLRRAEEAP
HHHHHHCCCCCCEEEEEECCHHHHHHHHHHCCCCHHHCHHHHHHHHHHHHHHHHHHHCCC
YRFAIIDSAQSIAQIQRRLEELIAIL
EEEEEHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA