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The map label for this gene is tig [H]

Identifier: 91783519

GI number: 91783519

Start: 2371868

End: 2373214

Strand: Direct

Name: tig [H]

Synonym: Bxe_A2296

Alternate gene names: 91783519

Gene position: 2371868-2373214 (Clockwise)

Preceding gene: 91783518

Following gene: 91783520

Centisome position: 48.45

GC content: 60.65

Gene sequence:

>1347_bases
ATGGCTAACGTTGTTGAAAACCTCGGCAAGCTCGAACGCCGCGTCACGATTTCCCTGCCGAAGGACGCCGTGCAGAAGGA
AGTGGATTCGCGTATCCGTCAACTCGCGAAGAACGTGCGCATGCCGGGTTTCCGCCCGGGCAAGGTGCCGCTCAAGATGG
TGACGCAACAGTATTCGGGTCAGGTGGAAGCCGAAGTGCTGAGCGACAAGGTCGGCAAGGAATTCTTCGACATCAGCCGC
GCCGAAAACCTGCGCGTCGCCGGTCAGCCGAGCTTCGCGCCGAAGACCGATGCCACTGAAGGCGACTACGCGTTCGACGC
AACGTTCGAGGTGTATCCGGAAGTGAAGCTGGGCGACGTCGCCACGGCAGAGATCGAGCGCACCACGACCACCATCAGCG
AAGCGGAAATCGACCGTACGCTGGACATCCTGCGCAAGCAGCGCGTGCACTTCCATGCTCGCGGCGAAGCCGGCGAGCAC
GGTGACGGCGGCGGCGACACGGCAGCGAAAGAAGGCGATCGCGTGACGGTCGACTTCGTCGGCAAGATCGAAGGTGAAGT
GTTCCAGGGCGGCAGCGCAGACGACTTCGCGTTCGTGCTGGGCGAGGGCCGCATGTTGCCGGAATTCGAGAAGGCGGCCA
CGGGCCTGAAGGTCGGCGAGTCGAAGGAATTCGATCTGGCATTCCCCGAGGACTACCACGGCAAGGAAGTCGCCGGCAAG
ACCGCGCAATTCACGATCACGATGAAGAAGATCGAGTGGCCGCACCTGCCGGAAATCGACGCGGAATTCGCGAAGTCGCT
CGGCATCGAAGACGGTGATCTGACCAAGATGCGCGCTGAGATCAAAGACAATCTCGAACGCGAAGCCAAGCGCCGCACGC
AGGCCATCGTCAAGAACCAGGTGATGGACGCGCTCCTGAAGATTTCCGAACTGGACGTGCCGAATGCGCTGATCGAACAG
GACCAGGAACGCCTCGTTGCGATGGCGCGTCAGGATCTGGAGCAGCGCGGCGTGCCGAACGCCAAAGACGCACCGATCCC
GGCCGCCATGTTCAAGGAACAGGCTGAGCGCCGCGTCAAGCTGGGCCTCGTGCTGGCCGAACTGGTAAAGGCCAATGAGT
TGCAGGCGAAGCCGGAGCAGATTCGTGCCGAAGTGGACGAATTCGCGAAAAGCTATGAAGACCCGAAGGAAGTCGTCCGC
TGGTATTATTCCAATCAGCAGCGCCTTGCCGAAATGGAAGCCTACGTCGTTGAAGCCAACGTCGTCGAATTCGTGCTCAG
CAAGGCCAAGGTGACGGACAAGGAAGTAAGCTTCGAAGAACTGGCAAGCGCAACGGCGCAAGCATAA

Upstream 100 bases:

>100_bases
CGCAATCGATGCTAAAGACGTGGTCGCGACATCGCGCAACATCGAAGCGGCACGGAGAAGATAACTGATTCGCTCGAATA
ATTTTAGGACGATTGAAGCC

Downstream 100 bases:

>100_bases
GCGTTGCTGCAACGGCGTGCCGGCTGTCGGAGCGACGGCCCGCACGCCGTTTTTTCGTGCTGTGAAAGTGTGTCGCATGT
GCATGGTGTTGCGCACACGC

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF [H]

Number of amino acids: Translated: 448; Mature: 447

Protein sequence:

>448_residues
MANVVENLGKLERRVTISLPKDAVQKEVDSRIRQLAKNVRMPGFRPGKVPLKMVTQQYSGQVEAEVLSDKVGKEFFDISR
AENLRVAGQPSFAPKTDATEGDYAFDATFEVYPEVKLGDVATAEIERTTTTISEAEIDRTLDILRKQRVHFHARGEAGEH
GDGGGDTAAKEGDRVTVDFVGKIEGEVFQGGSADDFAFVLGEGRMLPEFEKAATGLKVGESKEFDLAFPEDYHGKEVAGK
TAQFTITMKKIEWPHLPEIDAEFAKSLGIEDGDLTKMRAEIKDNLEREAKRRTQAIVKNQVMDALLKISELDVPNALIEQ
DQERLVAMARQDLEQRGVPNAKDAPIPAAMFKEQAERRVKLGLVLAELVKANELQAKPEQIRAEVDEFAKSYEDPKEVVR
WYYSNQQRLAEMEAYVVEANVVEFVLSKAKVTDKEVSFEELASATAQA

Sequences:

>Translated_448_residues
MANVVENLGKLERRVTISLPKDAVQKEVDSRIRQLAKNVRMPGFRPGKVPLKMVTQQYSGQVEAEVLSDKVGKEFFDISR
AENLRVAGQPSFAPKTDATEGDYAFDATFEVYPEVKLGDVATAEIERTTTTISEAEIDRTLDILRKQRVHFHARGEAGEH
GDGGGDTAAKEGDRVTVDFVGKIEGEVFQGGSADDFAFVLGEGRMLPEFEKAATGLKVGESKEFDLAFPEDYHGKEVAGK
TAQFTITMKKIEWPHLPEIDAEFAKSLGIEDGDLTKMRAEIKDNLEREAKRRTQAIVKNQVMDALLKISELDVPNALIEQ
DQERLVAMARQDLEQRGVPNAKDAPIPAAMFKEQAERRVKLGLVLAELVKANELQAKPEQIRAEVDEFAKSYEDPKEVVR
WYYSNQQRLAEMEAYVVEANVVEFVLSKAKVTDKEVSFEELASATAQA
>Mature_447_residues
ANVVENLGKLERRVTISLPKDAVQKEVDSRIRQLAKNVRMPGFRPGKVPLKMVTQQYSGQVEAEVLSDKVGKEFFDISRA
ENLRVAGQPSFAPKTDATEGDYAFDATFEVYPEVKLGDVATAEIERTTTTISEAEIDRTLDILRKQRVHFHARGEAGEHG
DGGGDTAAKEGDRVTVDFVGKIEGEVFQGGSADDFAFVLGEGRMLPEFEKAATGLKVGESKEFDLAFPEDYHGKEVAGKT
AQFTITMKKIEWPHLPEIDAEFAKSLGIEDGDLTKMRAEIKDNLEREAKRRTQAIVKNQVMDALLKISELDVPNALIEQD
QERLVAMARQDLEQRGVPNAKDAPIPAAMFKEQAERRVKLGLVLAELVKANELQAKPEQIRAEVDEFAKSYEDPKEVVRW
YYSNQQRLAEMEAYVVEANVVEFVLSKAKVTDKEVSFEELASATAQA

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation [H]

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786640, Length=443, Percent_Identity=40.1805869074492, Blast_Score=339, Evalue=3e-94,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881 [H]

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N [H]

EC number: NA

Molecular weight: Translated: 49880; Mature: 49749

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANVVENLGKLERRVTISLPKDAVQKEVDSRIRQLAKNVRMPGFRPGKVPLKMVTQQYSG
CCHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCC
QVEAEVLSDKVGKEFFDISRAENLRVAGQPSFAPKTDATEGDYAFDATFEVYPEVKLGDV
CHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCEEEECEEEECCCCEECCC
ATAEIERTTTTISEAEIDRTLDILRKQRVHFHARGEAGEHGDGGGDTAAKEGDRVTVDFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCEEEEEEE
GKIEGEVFQGGSADDFAFVLGEGRMLPEFEKAATGLKVGESKEFDLAFPEDYHGKEVAGK
ECCCCCEECCCCCCCEEEEECCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCHHCCC
TAQFTITMKKIEWPHLPEIDAEFAKSLGIEDGDLTKMRAEIKDNLEREAKRRTQAIVKNQ
CEEEEEEEEECCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VMDALLKISELDVPNALIEQDQERLVAMARQDLEQRGVPNAKDAPIPAAMFKEQAERRVK
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
LGLVLAELVKANELQAKPEQIRAEVDEFAKSYEDPKEVVRWYYSNQQRLAEMEAYVVEAN
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHH
VVEFVLSKAKVTDKEVSFEELASATAQA
HHHHHHHHHHCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure 
ANVVENLGKLERRVTISLPKDAVQKEVDSRIRQLAKNVRMPGFRPGKVPLKMVTQQYSG
CHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCC
QVEAEVLSDKVGKEFFDISRAENLRVAGQPSFAPKTDATEGDYAFDATFEVYPEVKLGDV
CHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCEEEECEEEECCCCEECCC
ATAEIERTTTTISEAEIDRTLDILRKQRVHFHARGEAGEHGDGGGDTAAKEGDRVTVDFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCEEEEEEE
GKIEGEVFQGGSADDFAFVLGEGRMLPEFEKAATGLKVGESKEFDLAFPEDYHGKEVAGK
ECCCCCEECCCCCCCEEEEECCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCHHCCC
TAQFTITMKKIEWPHLPEIDAEFAKSLGIEDGDLTKMRAEIKDNLEREAKRRTQAIVKNQ
CEEEEEEEEECCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VMDALLKISELDVPNALIEQDQERLVAMARQDLEQRGVPNAKDAPIPAAMFKEQAERRVK
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
LGLVLAELVKANELQAKPEQIRAEVDEFAKSYEDPKEVVRWYYSNQQRLAEMEAYVVEAN
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHH
VVEFVLSKAKVTDKEVSFEELASATAQA
HHHHHHHHHHCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA