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The map label for this gene is fabG [C]

Identifier: 91783111

GI number: 91783111

Start: 1961554

End: 1962324

Strand: Direct

Name: fabG [C]

Synonym: Bxe_A2696

Alternate gene names: 91783111

Gene position: 1961554-1962324 (Clockwise)

Preceding gene: 91783110

Following gene: 91783112

Centisome position: 40.07

GC content: 61.35

Gene sequence:

>771_bases
ATGCGTCCCGACTGTTTCACAAATGGAAACCCTATGAACATCAAAGGTTGTACGGCACTCGTCACAGGTGCCAATCGAGG
CTTGGGGAAGGTTATCGTCGACCAGCTGGCGCAGGCCGGTGCTGCCAGAATCTACGCCGGTATGCGTAATCCAGCTGTGA
TCGGGCACGACGTCGTTACGCCAGTCGCGCTCGATGTCACGGACGCGGATTCCGTGGCGCGCACGGCAGAGAAGTGCAGC
GATGTCGACCTGGTCATCAACAACGCAGGCATCATGCTCGCAACGCCAATGCTTGCTGACGATTCGGAACAGGCGCTGCG
CCGCGAACTGGATGTGAATGCGTTTGGCCCATTGCGCATCGCCAAGGCGTTTGCTCCGATCCTGGCGCGCAACGGCGGTG
GTGCGATTGTCAACATGCTGTCGGTGGTGAGCTGGTATGTCTATCCGTTCAACGCCACCTATTGCGCTTCGAAGTTCACG
GCACTGGCGATGACCGACGCCATGCGCGTGGAACTGAAGGCGCAGGGAACGCACGTGATGGGCGTCTATGCCGGCTTTAT
CGACACGGATATGGCCGCTCGCGTGACGGGCGAAAAGACCTCACCGGTTCAGGTTGCCGAGCGAATGCTGGCGGGCCTCC
GGGCAGGAAAGGATCACGTGCTTGCAGACGCCGCGGCCGAGGAGCTTTGGCGTGCGGTCAGGTTCGAGCCGGAGCGTGTT
GCCGCCTGGGCTCAATCGCTTTGGGACGCGGGTCGAGCGTGGGCCGTCTAG

Upstream 100 bases:

>100_bases
CGAATCCCGCAACGCGAGATCACAGCACGCAGGACAGGCTGATTGATCTGTGCGAGTCGTTCTCCGGTATCCGGCTGCCC
GATTGAGCACGCGGCCAAAG

Downstream 100 bases:

>100_bases
TATGACGAGCCGTTGCTCGCGTACCGGCTGGGGTTTCGTTCGTACAGGCCGGTTGGGACGCGCGGTGTGGCTGGCCCGTC
GGCGCGGGCGCAACGTAGCT

Product: putative short-chain oxidoreductase

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MRPDCFTNGNPMNIKGCTALVTGANRGLGKVIVDQLAQAGAARIYAGMRNPAVIGHDVVTPVALDVTDADSVARTAEKCS
DVDLVINNAGIMLATPMLADDSEQALRRELDVNAFGPLRIAKAFAPILARNGGGAIVNMLSVVSWYVYPFNATYCASKFT
ALAMTDAMRVELKAQGTHVMGVYAGFIDTDMAARVTGEKTSPVQVAERMLAGLRAGKDHVLADAAAEELWRAVRFEPERV
AAWAQSLWDAGRAWAV

Sequences:

>Translated_256_residues
MRPDCFTNGNPMNIKGCTALVTGANRGLGKVIVDQLAQAGAARIYAGMRNPAVIGHDVVTPVALDVTDADSVARTAEKCS
DVDLVINNAGIMLATPMLADDSEQALRRELDVNAFGPLRIAKAFAPILARNGGGAIVNMLSVVSWYVYPFNATYCASKFT
ALAMTDAMRVELKAQGTHVMGVYAGFIDTDMAARVTGEKTSPVQVAERMLAGLRAGKDHVLADAAAEELWRAVRFEPERV
AAWAQSLWDAGRAWAV
>Mature_256_residues
MRPDCFTNGNPMNIKGCTALVTGANRGLGKVIVDQLAQAGAARIYAGMRNPAVIGHDVVTPVALDVTDADSVARTAEKCS
DVDLVINNAGIMLATPMLADDSEQALRRELDVNAFGPLRIAKAFAPILARNGGGAIVNMLSVVSWYVYPFNATYCASKFT
ALAMTDAMRVELKAQGTHVMGVYAGFIDTDMAARVTGEKTSPVQVAERMLAGLRAGKDHVLADAAAEELWRAVRFEPERV
AAWAQSLWDAGRAWAV

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI223718074, Length=238, Percent_Identity=29.4117647058824, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI20149619, Length=244, Percent_Identity=29.0983606557377, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI142976729, Length=249, Percent_Identity=24.4979919678715, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI210032110, Length=255, Percent_Identity=24.3137254901961, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI7705925, Length=214, Percent_Identity=28.5046728971963, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI150247226, Length=193, Percent_Identity=30.5699481865285, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI40807363, Length=195, Percent_Identity=29.2307692307692, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI7657478, Length=194, Percent_Identity=29.3814432989691, Blast_Score=64, Evalue=1e-10,
Organism=Escherichia coli, GI1787335, Length=241, Percent_Identity=29.4605809128631, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87082100, Length=197, Percent_Identity=30.9644670050761, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1786701, Length=243, Percent_Identity=28.3950617283951, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17567345, Length=203, Percent_Identity=27.5862068965517, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17561402, Length=197, Percent_Identity=26.9035532994924, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17570069, Length=200, Percent_Identity=26.5, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=192, Percent_Identity=28.125, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322067, Length=201, Percent_Identity=27.363184079602, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21358495, Length=249, Percent_Identity=28.1124497991968, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24649181, Length=260, Percent_Identity=26.5384615384615, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24643142, Length=187, Percent_Identity=29.4117647058824, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 27297; Mature: 27297

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPDCFTNGNPMNIKGCTALVTGANRGLGKVIVDQLAQAGAARIYAGMRNPAVIGHDVVT
CCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCHHHHHHCCCCCCEECCCCCC
PVALDVTDADSVARTAEKCSDVDLVINNAGIMLATPMLADDSEQALRRELDVNAFGPLRI
CEEEECCCHHHHHHHHHHCCCCEEEEECCCEEEEECCCCCCHHHHHHHHCCCCCCCHHHH
AKAFAPILARNGGGAIVNMLSVVSWYVYPFNATYCASKFTALAMTDAMRVELKAQGTHVM
HHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEEEEEECCCEEE
GVYAGFIDTDMAARVTGEKTSPVQVAERMLAGLRAGKDHVLADAAAEELWRAVRFEPERV
EEEHHHHCCCHHHEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHH
AAWAQSLWDAGRAWAV
HHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRPDCFTNGNPMNIKGCTALVTGANRGLGKVIVDQLAQAGAARIYAGMRNPAVIGHDVVT
CCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCHHHHHHCCCCCCEECCCCCC
PVALDVTDADSVARTAEKCSDVDLVINNAGIMLATPMLADDSEQALRRELDVNAFGPLRI
CEEEECCCHHHHHHHHHHCCCCEEEEECCCEEEEECCCCCCHHHHHHHHCCCCCCCHHHH
AKAFAPILARNGGGAIVNMLSVVSWYVYPFNATYCASKFTALAMTDAMRVELKAQGTHVM
HHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEEEEEECCCEEE
GVYAGFIDTDMAARVTGEKTSPVQVAERMLAGLRAGKDHVLADAAAEELWRAVRFEPERV
EEEHHHHCCCHHHEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHH
AAWAQSLWDAGRAWAV
HHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA