Click here to switch to the map view.

The map label for this gene is hutH [H]

Identifier: 91782876

GI number: 91782876

Start: 1664927

End: 1666450

Strand: Direct

Name: hutH [H]

Synonym: Bxe_A2947

Alternate gene names: 91782876

Gene position: 1664927-1666450 (Clockwise)

Preceding gene: 91782875

Following gene: 91782877

Centisome position: 34.01

GC content: 65.62

Gene sequence:

>1524_bases
ATGATGAATCTGAAGCCCGGCCACCTGACTCTCCCGCAACTGCGCCAGATCGCGCGCGAACATGTCGCATTGCAACTCGA
TCCCGCCAGCCATGCCGCGATCGACGCCTGCGCGCAAGCCGTCGCCGATATCGCCGCGAAGGGCGAGCCGGCCTACGGCA
TCAACACGGGCTTTGGGCGCCTCGCCAGCACGCATATTCCGCACGACCAACTCGAACTGTTGCAGCGCAATCTGGTGCTC
TCTCACGCGGTCGGCGTGGGTGAGCCGATGTCGCGTCCGGTCGTGCGTCTGCTGATCGCGCTGAAACTCTCGAGCCTCGG
CCGCGGCCATTCGGGCATTCGCCGTGAAGTGATGGACGCGCTGATCACGCTGTACAACGCCGACGTGCTGCCGGTGATTC
CGGTCAAGGGTTCGGTCGGTGCATCGGGCGACCTCGCGCCGCTCGCGCATATGTCGGCGGCGCTGCTCGGCGTCGGCGAA
GTGTTCGCGAAGGGCGAGCGCATGCCGGCCACCGAGGGTCTCGCGCTCGTCGGCCTCAAGCCGCTCACGCTGCAAGCCAA
AGAGGGGCTGGCGCTCCTGAACGGCACGCAGGCTTCGACGGCGCTCGCGCTGTACAACATGTTCGCCATCGAAGACCTGT
ACCGCACCGCGCTGGTGTCGGGCGCATTGTCGGTAGATGCCGCAATGGGCTCGGTCAAGCCGTTCGACGCGCGCATTCAC
GAGTTGCGCGGCCATCAAGGTCAGATCGACGCGGCGGCGGCATACCGCTCGCTGCTGGAAGGTTCGGCAATCAACGTTTC
GCACGCCGATTGCGACAAGGTGCAGGACCCGTACAGCCTGCGCTGCCAGCCGCAAGTCATGGGCGCGTGTCTGGATCAGA
TGCGCCACGCGGCCAACGTGCTGCTGCTCGAAGCGAACGCGGTCTCCGACAATCCGCTGATTTTCCCCGACACCGGCGAA
GTGCTGTCGGGCGGTAACTTCCACGCAGAGCCGGTCGCCTTCGCGGCCGATAACCTCGCGCTCGCCGCCGCCGAAATCGG
CGCGCTGGCCGAACGCCGCATCGCGCTGCTGATCGACGCGACGCTGTCGGGCCTGCCGCCGTTCCTCGTGCGCGATGGCG
GCGTGAATTCGGGCTTCATGATCGCGCACGTCACGGCTGCGGCGCTCGCCTCGGAAAACAAGACGCTCGCGCATCCGGCT
TCGGTCGATTCGCTGCCCACTTCGGCAAACCAGGAAGACCACGTGTCGATGGCGACGTTCGCCGCGCGCAAGCTCGGCGA
CATTGCTGAAAACACCGCGAACATTCTGTCGATCGAACTGCTCGCCGCCGCGCAAGGCGTCGATCTGCGCGCGCCGCACA
AGACCAGCCCGAGCCTGCAGAAAGCGATGGACACAGTGCGCAAGGACGTCGCGCATTACGAGCTCGACCATTATTTCGCA
CCGGATATCGCGGCTGTCACGCGCCTCGTGCAGAACGGCACGATCGCGAAGCTGAGCCCGTTCTCCTTCGCGTCCGAACA
GTAA

Upstream 100 bases:

>100_bases
CCCTAATGGAAACTCCCAGGCCGAATCCTTGAAAAACAAGTTGTATATACAAGAAGGCGCCGCTAAACTTCTCTCGAATT
GTATAGACAGGACGACAACC

Downstream 100 bases:

>100_bases
GTTTCAAGCACGCATATCAAGCCAATGAACGCACCGGCCTATCAGGGCATCAAGGACTTCATCCTCGCGCGCATCCATGC
GGGCGAATGGGGTGAAGGCG

Product: histidine ammonia-lyase

Products: NA

Alternate protein names: Histidase [H]

Number of amino acids: Translated: 507; Mature: 507

Protein sequence:

>507_residues
MMNLKPGHLTLPQLRQIAREHVALQLDPASHAAIDACAQAVADIAAKGEPAYGINTGFGRLASTHIPHDQLELLQRNLVL
SHAVGVGEPMSRPVVRLLIALKLSSLGRGHSGIRREVMDALITLYNADVLPVIPVKGSVGASGDLAPLAHMSAALLGVGE
VFAKGERMPATEGLALVGLKPLTLQAKEGLALLNGTQASTALALYNMFAIEDLYRTALVSGALSVDAAMGSVKPFDARIH
ELRGHQGQIDAAAAYRSLLEGSAINVSHADCDKVQDPYSLRCQPQVMGACLDQMRHAANVLLLEANAVSDNPLIFPDTGE
VLSGGNFHAEPVAFAADNLALAAAEIGALAERRIALLIDATLSGLPPFLVRDGGVNSGFMIAHVTAAALASENKTLAHPA
SVDSLPTSANQEDHVSMATFAARKLGDIAENTANILSIELLAAAQGVDLRAPHKTSPSLQKAMDTVRKDVAHYELDHYFA
PDIAAVTRLVQNGTIAKLSPFSFASEQ

Sequences:

>Translated_507_residues
MMNLKPGHLTLPQLRQIAREHVALQLDPASHAAIDACAQAVADIAAKGEPAYGINTGFGRLASTHIPHDQLELLQRNLVL
SHAVGVGEPMSRPVVRLLIALKLSSLGRGHSGIRREVMDALITLYNADVLPVIPVKGSVGASGDLAPLAHMSAALLGVGE
VFAKGERMPATEGLALVGLKPLTLQAKEGLALLNGTQASTALALYNMFAIEDLYRTALVSGALSVDAAMGSVKPFDARIH
ELRGHQGQIDAAAAYRSLLEGSAINVSHADCDKVQDPYSLRCQPQVMGACLDQMRHAANVLLLEANAVSDNPLIFPDTGE
VLSGGNFHAEPVAFAADNLALAAAEIGALAERRIALLIDATLSGLPPFLVRDGGVNSGFMIAHVTAAALASENKTLAHPA
SVDSLPTSANQEDHVSMATFAARKLGDIAENTANILSIELLAAAQGVDLRAPHKTSPSLQKAMDTVRKDVAHYELDHYFA
PDIAAVTRLVQNGTIAKLSPFSFASEQ
>Mature_507_residues
MMNLKPGHLTLPQLRQIAREHVALQLDPASHAAIDACAQAVADIAAKGEPAYGINTGFGRLASTHIPHDQLELLQRNLVL
SHAVGVGEPMSRPVVRLLIALKLSSLGRGHSGIRREVMDALITLYNADVLPVIPVKGSVGASGDLAPLAHMSAALLGVGE
VFAKGERMPATEGLALVGLKPLTLQAKEGLALLNGTQASTALALYNMFAIEDLYRTALVSGALSVDAAMGSVKPFDARIH
ELRGHQGQIDAAAAYRSLLEGSAINVSHADCDKVQDPYSLRCQPQVMGACLDQMRHAANVLLLEANAVSDNPLIFPDTGE
VLSGGNFHAEPVAFAADNLALAAAEIGALAERRIALLIDATLSGLPPFLVRDGGVNSGFMIAHVTAAALASENKTLAHPA
SVDSLPTSANQEDHVSMATFAARKLGDIAENTANILSIELLAAAQGVDLRAPHKTSPSLQKAMDTVRKDVAHYELDHYFA
PDIAAVTRLVQNGTIAKLSPFSFASEQ

Specific function: Unknown

COG id: COG2986

COG function: function code E; Histidine ammonia-lyase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAL/histidase family [H]

Homologues:

Organism=Homo sapiens, GI4504333, Length=494, Percent_Identity=45.3441295546559, Blast_Score=417, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI17567831, Length=497, Percent_Identity=42.4547283702213, Blast_Score=368, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005921
- InterPro:   IPR008948
- InterPro:   IPR001106
- InterPro:   IPR022313 [H]

Pfam domain/function: PF00221 PAL [H]

EC number: =4.3.1.3 [H]

Molecular weight: Translated: 53242; Mature: 53242

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS00488 PAL_HISTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNLKPGHLTLPQLRQIAREHVALQLDPASHAAIDACAQAVADIAAKGEPAYGINTGFGR
CCCCCCCCCCHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
LASTHIPHDQLELLQRNLVLSHAVGVGEPMSRPVVRLLIALKLSSLGRGHSGIRREVMDA
HHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LITLYNADVLPVIPVKGSVGASGDLAPLAHMSAALLGVGEVFAKGERMPATEGLALVGLK
HHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCC
PLTLQAKEGLALLNGTQASTALALYNMFAIEDLYRTALVSGALSVDAAMGSVKPFDARIH
CEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
ELRGHQGQIDAAAAYRSLLEGSAINVSHADCDKVQDPYSLRCQPQVMGACLDQMRHAANV
HHCCCCCCCHHHHHHHHHHCCCCEECCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHCE
LLLEANAVSDNPLIFPDTGEVLSGGNFHAEPVAFAADNLALAAAEIGALAERRIALLIDA
EEEEECCCCCCCEEECCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHEEEEEEC
TLSGLPPFLVRDGGVNSGFMIAHVTAAALASENKTLAHPASVDSLPTSANQEDHVSMATF
HHCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
AARKLGDIAENTANILSIELLAAAQGVDLRAPHKTSPSLQKAMDTVRKDVAHYELDHYFA
HHHHHHHHHHHHHHHEEEEEHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
PDIAAVTRLVQNGTIAKLSPFSFASEQ
CCHHHHHHHHHCCCEEEECCCCCCCCC
>Mature Secondary Structure
MMNLKPGHLTLPQLRQIAREHVALQLDPASHAAIDACAQAVADIAAKGEPAYGINTGFGR
CCCCCCCCCCHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
LASTHIPHDQLELLQRNLVLSHAVGVGEPMSRPVVRLLIALKLSSLGRGHSGIRREVMDA
HHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LITLYNADVLPVIPVKGSVGASGDLAPLAHMSAALLGVGEVFAKGERMPATEGLALVGLK
HHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCC
PLTLQAKEGLALLNGTQASTALALYNMFAIEDLYRTALVSGALSVDAAMGSVKPFDARIH
CEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
ELRGHQGQIDAAAAYRSLLEGSAINVSHADCDKVQDPYSLRCQPQVMGACLDQMRHAANV
HHCCCCCCCHHHHHHHHHHCCCCEECCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHCE
LLLEANAVSDNPLIFPDTGEVLSGGNFHAEPVAFAADNLALAAAEIGALAERRIALLIDA
EEEEECCCCCCCEEECCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHEEEEEEC
TLSGLPPFLVRDGGVNSGFMIAHVTAAALASENKTLAHPASVDSLPTSANQEDHVSMATF
HHCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
AARKLGDIAENTANILSIELLAAAQGVDLRAPHKTSPSLQKAMDTVRKDVAHYELDHYFA
HHHHHHHHHHHHHHHEEEEEHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
PDIAAVTRLVQNGTIAKLSPFSFASEQ
CCHHHHHHHHHCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA