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The map label for this gene is lcrD [H]

Identifier: 91782706

GI number: 91782706

Start: 1482444

End: 1484522

Strand: Direct

Name: lcrD [H]

Synonym: Bxe_A3119

Alternate gene names: 91782706

Gene position: 1482444-1484522 (Clockwise)

Preceding gene: 91782705

Following gene: 91782707

Centisome position: 30.28

GC content: 66.33

Gene sequence:

>2079_bases
ATGTCGAACCGTTCCATTCTCAGCCGCTACGATCTGTCGGCTTTTTTTGCGCGTCATGCGGACCTCGCCGTCGGCATCGG
CATTCTGGCGGTTCTTGCCTTGCTGATCGTGCCGGTGCCGCCGTTCGTGCTCGATCTGTTCATCTGCGTGAGCTTCGCCG
CCGGGCTGACGATGCTCACCACCACGCTGTATGTGTCGAAAGCCGCGGATCTCGCGAGCTTTCCGTCGCTGCTGCTGATC
ACGACGTTGCTGCGCCTCGCGCTGGCCATCGCCTCCACCAAGATGATCCTGCTTCATGCGCACGCCGGCCAGATCATCGG
CGCGTTCGGTGAAATGGTGGTGGGCGGCAATGTGGCGGTCGGCCTCGTGGTTTTCGTGGTGCTGGCGGCGATCCAGTTCA
TCGTCGTGGCGAAAGGCGCGGACCGTGTCGCGGAAGTGGCGGCGCGCTTCACGCTCGACGGCATTCCGGGGCGGCAGATG
AGTATCGACGCCGATATGCGCAACGGTGTGGTCACGCCCGCCCAGGCGAGCCGTCTGCGCGCGTCGCTCGAACGCGAAAC
CTATTTCTACGGCTCGCTCGACGGCGCGATGAAGTTCGTCAAGGGCGATGCGGTGGCGGGCCTCGTGGTGGCGCTGGTGA
ATATCGTCGGCGGACTGGCGGTCGGTATCGCGCAGCGCGGCATGTCGTTCGGCGACGCGCTGCGCACGTACACGATTCTG
ACGGTCGGCGACGGCCTCGTGTCGCAGATTCCGTCGCTGATCGTCTCGGTGGCCGCGGGTATTCTGGTCACCCGGGTGAG
CGCGGCCGACGGCGCCGACGCCCATCTCGGCAGTGACATTTACAGGCAACTGGCGGCGCATCCGAAAGCGATCGGCATGG
CCGGCGTGGCGTGTCTTTCTCTGGGTGTGATTCCAGGTTTTCCGCATGTCCAGTTCCTGGTGGCCGGCGGCTTGCTGCTC
GCGCTCGCGATCACGCTGATGCGCAACGCCGCGCTCGCGACCAACTCGCAGCGCGCGCTGATGCCCGGCTTGACGCGCGA
CGGCGGCAACTACGTGCCGCGTATTCTCGACGACGTCGAGTTGGGTACAAGCGCGGCGTTGCGCTTGCGGCTCGGTCTGG
AGGCGTTCGACGCGTTGCGGCCCGAGGCGCTGAACCGCCAGCTCGGTCAATTGCGCCGCAAGCTGATGGTCGAGCTGGGC
GTGCCGTTTCCGGGTCTCGCGTTGCTGCGTGATGCGCGGCTCGCGCCCGAGCGCTACGTCGTGGATATCGAAGACGTGCC
GTTTGCGAGCGGCACGCTGGTCGACGCGCACACGCTGGTGAGCGGTGACGAGAGCCGCGTCGTGTTCGACGGCGTGGCGG
GCTACCGGCCGCGCGCGGCGAAATCGGTCTGGGTGCCGAGCGCGACGGCGGCCTCGCTCGACGATCCTGAGCTCCACAAG
GCGAGTGTCGACGAGGCGCTGTGCGATCACCTCGCGGAAGTCTGCGAGCGTTCGGCGGCCGATTTTCTCGGCGTCCAGGA
GACGCGCTTTCTGCTCGATCAGCTGTCGATCGAATTTCGCGAGCTGGTCGCTCAAGTGGGGCAGACCGTGAACACGGTGC
AGCTCGCCGGTGTGCTGCGCCAGTTGCTGCAGCAGCGCGTGCCGATCCGCAATCTGCGCGCGATTCTCGAAGCCGTCGTC
CGCGTGCCGGCGGCCGAGCGCACCACCGACCGGATGGTGCGGCAGGCGCGCATCCAGCTGGGGCCGCAGATCGCGCGCGG
CTATGCCGACCTGGAGTCATGGACGATCTTCGCGGCGGTGCTGGAGCCCTCCTGGGAAGCCGAGCTCGAAGCGCAGATCA
GAAGCGGGGTCGACGGTGAACCGCAATGCGTGCTTTCGGTGGAGGAACTGGAGCGTGCGCAACGGGTTTTCGCCATCGAC
ATGAACGGGGTCGCGCTGATCGTGACGAATGCGGTTTTGCGTCCGCATCTGGCGAGGCTGCTGCACGACTTCGGGCGGCG
CGTCGACGTATTGGCCATCGAAGAGATTCCGCTCGACGTGTACCGTGTCGAGGCCGTTGCGACGCTGGGCGACGCATGA

Upstream 100 bases:

>100_bases
ATGGACAAAAACGAAATCAAACGCGAATTCCGCGACGACGAAGGCGACCCTTACGTAAAAAGCCGTCGCCGCGCGCTTCA
TCGGGAGCTTGGCCAATAAC

Downstream 100 bases:

>100_bases
AGGAGAACCTGATGCCCTCTATGGGGAAAACCGCGCCGGTGTTTCTGTCCGCGCCCGCGTTGCGCGGCCGGGTGGTGGAA
GCGCGCGGCGTGATCGCACG

Product: putative membrane low calcium response protein, LcrD, Type III secretion

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 692; Mature: 691

Protein sequence:

>692_residues
MSNRSILSRYDLSAFFARHADLAVGIGILAVLALLIVPVPPFVLDLFICVSFAAGLTMLTTTLYVSKAADLASFPSLLLI
TTLLRLALAIASTKMILLHAHAGQIIGAFGEMVVGGNVAVGLVVFVVLAAIQFIVVAKGADRVAEVAARFTLDGIPGRQM
SIDADMRNGVVTPAQASRLRASLERETYFYGSLDGAMKFVKGDAVAGLVVALVNIVGGLAVGIAQRGMSFGDALRTYTIL
TVGDGLVSQIPSLIVSVAAGILVTRVSAADGADAHLGSDIYRQLAAHPKAIGMAGVACLSLGVIPGFPHVQFLVAGGLLL
ALAITLMRNAALATNSQRALMPGLTRDGGNYVPRILDDVELGTSAALRLRLGLEAFDALRPEALNRQLGQLRRKLMVELG
VPFPGLALLRDARLAPERYVVDIEDVPFASGTLVDAHTLVSGDESRVVFDGVAGYRPRAAKSVWVPSATAASLDDPELHK
ASVDEALCDHLAEVCERSAADFLGVQETRFLLDQLSIEFRELVAQVGQTVNTVQLAGVLRQLLQQRVPIRNLRAILEAVV
RVPAAERTTDRMVRQARIQLGPQIARGYADLESWTIFAAVLEPSWEAELEAQIRSGVDGEPQCVLSVEELERAQRVFAID
MNGVALIVTNAVLRPHLARLLHDFGRRVDVLAIEEIPLDVYRVEAVATLGDA

Sequences:

>Translated_692_residues
MSNRSILSRYDLSAFFARHADLAVGIGILAVLALLIVPVPPFVLDLFICVSFAAGLTMLTTTLYVSKAADLASFPSLLLI
TTLLRLALAIASTKMILLHAHAGQIIGAFGEMVVGGNVAVGLVVFVVLAAIQFIVVAKGADRVAEVAARFTLDGIPGRQM
SIDADMRNGVVTPAQASRLRASLERETYFYGSLDGAMKFVKGDAVAGLVVALVNIVGGLAVGIAQRGMSFGDALRTYTIL
TVGDGLVSQIPSLIVSVAAGILVTRVSAADGADAHLGSDIYRQLAAHPKAIGMAGVACLSLGVIPGFPHVQFLVAGGLLL
ALAITLMRNAALATNSQRALMPGLTRDGGNYVPRILDDVELGTSAALRLRLGLEAFDALRPEALNRQLGQLRRKLMVELG
VPFPGLALLRDARLAPERYVVDIEDVPFASGTLVDAHTLVSGDESRVVFDGVAGYRPRAAKSVWVPSATAASLDDPELHK
ASVDEALCDHLAEVCERSAADFLGVQETRFLLDQLSIEFRELVAQVGQTVNTVQLAGVLRQLLQQRVPIRNLRAILEAVV
RVPAAERTTDRMVRQARIQLGPQIARGYADLESWTIFAAVLEPSWEAELEAQIRSGVDGEPQCVLSVEELERAQRVFAID
MNGVALIVTNAVLRPHLARLLHDFGRRVDVLAIEEIPLDVYRVEAVATLGDA
>Mature_691_residues
SNRSILSRYDLSAFFARHADLAVGIGILAVLALLIVPVPPFVLDLFICVSFAAGLTMLTTTLYVSKAADLASFPSLLLIT
TLLRLALAIASTKMILLHAHAGQIIGAFGEMVVGGNVAVGLVVFVVLAAIQFIVVAKGADRVAEVAARFTLDGIPGRQMS
IDADMRNGVVTPAQASRLRASLERETYFYGSLDGAMKFVKGDAVAGLVVALVNIVGGLAVGIAQRGMSFGDALRTYTILT
VGDGLVSQIPSLIVSVAAGILVTRVSAADGADAHLGSDIYRQLAAHPKAIGMAGVACLSLGVIPGFPHVQFLVAGGLLLA
LAITLMRNAALATNSQRALMPGLTRDGGNYVPRILDDVELGTSAALRLRLGLEAFDALRPEALNRQLGQLRRKLMVELGV
PFPGLALLRDARLAPERYVVDIEDVPFASGTLVDAHTLVSGDESRVVFDGVAGYRPRAAKSVWVPSATAASLDDPELHKA
SVDEALCDHLAEVCERSAADFLGVQETRFLLDQLSIEFRELVAQVGQTVNTVQLAGVLRQLLQQRVPIRNLRAILEAVVR
VPAAERTTDRMVRQARIQLGPQIARGYADLESWTIFAAVLEPSWEAELEAQIRSGVDGEPQCVLSVEELERAQRVFAIDM
NGVALIVTNAVLRPHLARLLHDFGRRVDVLAIEEIPLDVYRVEAVATLGDA

Specific function: Could be involved in the secretion of the yop virulence proteins [H]

COG id: COG4789

COG function: function code U; Type III secretory pathway, component EscV

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=718, Percent_Identity=33.7047353760446, Blast_Score=323, Evalue=3e-89,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001712
- InterPro:   IPR006302 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 73798; Mature: 73667

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNRSILSRYDLSAFFARHADLAVGIGILAVLALLIVPVPPFVLDLFICVSFAAGLTMLT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
TTLYVSKAADLASFPSLLLITTLLRLALAIASTKMILLHAHAGQIIGAFGEMVVGGNVAV
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHCCCCHHH
GLVVFVVLAAIQFIVVAKGADRVAEVAARFTLDGIPGRQMSIDADMRNGVVTPAQASRLR
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEECCHHHCCCCCCHHHHHHH
ASLERETYFYGSLDGAMKFVKGDAVAGLVVALVNIVGGLAVGIAQRGMSFGDALRTYTIL
HHHHHHHEEEECHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHEEEE
TVGDGLVSQIPSLIVSVAAGILVTRVSAADGADAHLGSDIYRQLAAHPKAIGMAGVACLS
EECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCHHHHHHHHCCCHHHHHHHHHHHH
LGVIPGFPHVQFLVAGGLLLALAITLMRNAALATNSQRALMPGLTRDGGNYVPRILDDVE
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCHHHHHHHHH
LGTSAALRLRLGLEAFDALRPEALNRQLGQLRRKLMVELGVPFPGLALLRDARLAPERYV
CCCHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCEE
VDIEDVPFASGTLVDAHTLVSGDESRVVFDGVAGYRPRAAKSVWVPSATAASLDDPELHK
EEECCCCCCCCCEEEHHHHCCCCCCEEEEECCCCCCCCCCCEEECCCCCCCCCCCCHHHH
ASVDEALCDHLAEVCERSAADFLGVQETRFLLDQLSIEFRELVAQVGQTVNTVQLAGVLR
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
QLLQQRVPIRNLRAILEAVVRVPAAERTTDRMVRQARIQLGPQIARGYADLESWTIFAAV
HHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHEEEEEE
LEPSWEAELEAQIRSGVDGEPQCVLSVEELERAQRVFAIDMNGVALIVTNAVLRPHLARL
CCCCCHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHEEEEECCCEEEEEHHHHHHHHHHHH
LHDFGRRVDVLAIEEIPLDVYRVEAVATLGDA
HHHHCCCEEEEEEECCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
SNRSILSRYDLSAFFARHADLAVGIGILAVLALLIVPVPPFVLDLFICVSFAAGLTMLT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
TTLYVSKAADLASFPSLLLITTLLRLALAIASTKMILLHAHAGQIIGAFGEMVVGGNVAV
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHCCCCHHH
GLVVFVVLAAIQFIVVAKGADRVAEVAARFTLDGIPGRQMSIDADMRNGVVTPAQASRLR
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEECCHHHCCCCCCHHHHHHH
ASLERETYFYGSLDGAMKFVKGDAVAGLVVALVNIVGGLAVGIAQRGMSFGDALRTYTIL
HHHHHHHEEEECHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHEEEE
TVGDGLVSQIPSLIVSVAAGILVTRVSAADGADAHLGSDIYRQLAAHPKAIGMAGVACLS
EECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCHHHHHHHHCCCHHHHHHHHHHHH
LGVIPGFPHVQFLVAGGLLLALAITLMRNAALATNSQRALMPGLTRDGGNYVPRILDDVE
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCHHHHHHHHH
LGTSAALRLRLGLEAFDALRPEALNRQLGQLRRKLMVELGVPFPGLALLRDARLAPERYV
CCCHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCEE
VDIEDVPFASGTLVDAHTLVSGDESRVVFDGVAGYRPRAAKSVWVPSATAASLDDPELHK
EEECCCCCCCCCEEEHHHHCCCCCCEEEEECCCCCCCCCCCEEECCCCCCCCCCCCHHHH
ASVDEALCDHLAEVCERSAADFLGVQETRFLLDQLSIEFRELVAQVGQTVNTVQLAGVLR
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
QLLQQRVPIRNLRAILEAVVRVPAAERTTDRMVRQARIQLGPQIARGYADLESWTIFAAV
HHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHEEEEEE
LEPSWEAELEAQIRSGVDGEPQCVLSVEELERAQRVFAIDMNGVALIVTNAVLRPHLARL
CCCCCHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHEEEEECCCEEEEEHHHHHHHHHHHH
LHDFGRRVDVLAIEEIPLDVYRVEAVATLGDA
HHHHCCCEEEEEEECCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11402007 [H]