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The map label for this gene is nuoN [H]

Identifier: 91782625

GI number: 91782625

Start: 1395934

End: 1397406

Strand: Direct

Name: nuoN [H]

Synonym: Bxe_A3201

Alternate gene names: 91782625

Gene position: 1395934-1397406 (Clockwise)

Preceding gene: 91782624

Following gene: 91782626

Centisome position: 28.51

GC content: 62.53

Gene sequence:

>1473_bases
ATGCAAAACGCCCCTATGACTGCTCTGTTGCCCGACGCGCTGGTGATGCTCGCCGTTGTCGTCGCGTGGCTCAACGACAC
GTTCGTCGGCCAGGCCGGTCGCCGTACCACGTATTTCATCGCGTTCTTCTCGACGCTGGTCGCCGGCATCTGGTTCGCGA
TGAATGCGTTCGACCCGCAAGTGCGCTACTACTTCGGCCACATGTACGTGGTGGATTCGTTCGCCAACGTGATGAAAGCG
GTGGTGACGCTCGGCTACGCCGTGTCGATCGTCTACTCGCGCCGCTACCTCGAGGATCGCGGGCTGTTCCGCGGCGAGTT
CTTCCTGCTGGGTATGTTCTCGTTGCTCGGCCAGCTCGTCATGATCTCCGGCAACAACTTCCTGACGCTGTATCTCGGCC
TGGAGCTGATGTCGCTGTCGCTGTACGCGGCGATCGCCCTGCGTCGTGATGCGGCGCAGTCGAACGAGGCGGCCATGAAG
TACTACGTGCTCGGCGCGCTGGCTTCCGGCTTCCTGCTGTACGGTATCTCGATGCTGTACGGCGCGACCGGTTCGCTCGA
CCTGAACGAAGTGTTCAAGGCGATCGGCACGAGCCACTACGACCCGAGCGTGCTGCTGTTCGGCGTGATCTTCATCGTGG
CGGGCGTGGCGTTCAAGATGGGGGCGGTGCCGTTCCACATGTGGGTGCCCGACGTGTATCAGGGCGCTCCGACGGCCATG
ACGCTGATGGTCGGCGGCGGTCCGAAAGTGGCCGCGTTCGCGTGGGGCTTGCGCTTCCTGGTGATGGGTCTGCTGCCGCT
GGCGGTGGAATGGCAGCAGATGCTGGTGATTCTCGCGGCGCTTTCGCTGATCGTCGGCAACATTACCGGTATCGTGCAGC
GCAACGTCAAGCGGATGCTCGCTTACTCGGCGATCTCGAACATGGGCTTCGTGCTGCTGGGCCTGCTGGCCGGCGTGGTC
GACAGCAAGACCACGGGCGCCGCCAATGCGTATGGCTCGGCCATGTACTACAGCATCGTCTACCTGATCACGACGATGGG
TACGTTCGGCGTCGTCATGCTGTTGGCTCGCCGCGATTTCGAAGCCGACACGCTCGAGGACTTCAAGGGTCTGAACCAGC
GCAGCCCGGTTTTCGCGTTCGTGATGATGATCATGATGTTCTCGCTCGCCGGCATTCCGCCCGCGGTCGGTTTCTACGCG
AAGCTCGCGGTGCTGCAGGCCACCATGAACGCCGGCTTGACCTGGCTGACGGTGCTGGCCGTGATCACCTCGCTGTTCGG
CGCGTTCTACTACCTGCGTATCGTCAAGCTGATGTATTTCGACGATCCGCAAGACAAGTCGCCCATTCTCGCCGACACCA
GCACGCGTGCGTTGCTCGCCTTCAACGGCGTGGCCGTGCTGGTGCTCGGCATCGTGCCGGATCCGTTGTTGAAGGCCTGC
CTGCAGGCTATCCAGCACACGCTGCTGCTCTGA

Upstream 100 bases:

>100_bases
ACCGATGTGATGCACGTATCCGTGGAAAACCTCCTCTCCCACGTTGCGCAATCAAAGCTGCCGTTGCCTCAGTAACGCAG
AGCGGAGGAATTTAAAGACC

Downstream 100 bases:

>100_bases
TGTCGGCGGCGGGTTGGTTTATCGTGCTGTTGGCGCTGGCGGGCGCCAACCTGCCGTTCCTGAATCAGCGCCTCTTCGCC
GCCGTGCCGTTGAAAGCGGC

Product: NADH dehydrogenase subunit N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MQNAPMTALLPDALVMLAVVVAWLNDTFVGQAGRRTTYFIAFFSTLVAGIWFAMNAFDPQVRYYFGHMYVVDSFANVMKA
VVTLGYAVSIVYSRRYLEDRGLFRGEFFLLGMFSLLGQLVMISGNNFLTLYLGLELMSLSLYAAIALRRDAAQSNEAAMK
YYVLGALASGFLLYGISMLYGATGSLDLNEVFKAIGTSHYDPSVLLFGVIFIVAGVAFKMGAVPFHMWVPDVYQGAPTAM
TLMVGGGPKVAAFAWGLRFLVMGLLPLAVEWQQMLVILAALSLIVGNITGIVQRNVKRMLAYSAISNMGFVLLGLLAGVV
DSKTTGAANAYGSAMYYSIVYLITTMGTFGVVMLLARRDFEADTLEDFKGLNQRSPVFAFVMMIMMFSLAGIPPAVGFYA
KLAVLQATMNAGLTWLTVLAVITSLFGAFYYLRIVKLMYFDDPQDKSPILADTSTRALLAFNGVAVLVLGIVPDPLLKAC
LQAIQHTLLL

Sequences:

>Translated_490_residues
MQNAPMTALLPDALVMLAVVVAWLNDTFVGQAGRRTTYFIAFFSTLVAGIWFAMNAFDPQVRYYFGHMYVVDSFANVMKA
VVTLGYAVSIVYSRRYLEDRGLFRGEFFLLGMFSLLGQLVMISGNNFLTLYLGLELMSLSLYAAIALRRDAAQSNEAAMK
YYVLGALASGFLLYGISMLYGATGSLDLNEVFKAIGTSHYDPSVLLFGVIFIVAGVAFKMGAVPFHMWVPDVYQGAPTAM
TLMVGGGPKVAAFAWGLRFLVMGLLPLAVEWQQMLVILAALSLIVGNITGIVQRNVKRMLAYSAISNMGFVLLGLLAGVV
DSKTTGAANAYGSAMYYSIVYLITTMGTFGVVMLLARRDFEADTLEDFKGLNQRSPVFAFVMMIMMFSLAGIPPAVGFYA
KLAVLQATMNAGLTWLTVLAVITSLFGAFYYLRIVKLMYFDDPQDKSPILADTSTRALLAFNGVAVLVLGIVPDPLLKAC
LQAIQHTLLL
>Mature_490_residues
MQNAPMTALLPDALVMLAVVVAWLNDTFVGQAGRRTTYFIAFFSTLVAGIWFAMNAFDPQVRYYFGHMYVVDSFANVMKA
VVTLGYAVSIVYSRRYLEDRGLFRGEFFLLGMFSLLGQLVMISGNNFLTLYLGLELMSLSLYAAIALRRDAAQSNEAAMK
YYVLGALASGFLLYGISMLYGATGSLDLNEVFKAIGTSHYDPSVLLFGVIFIVAGVAFKMGAVPFHMWVPDVYQGAPTAM
TLMVGGGPKVAAFAWGLRFLVMGLLPLAVEWQQMLVILAALSLIVGNITGIVQRNVKRMLAYSAISNMGFVLLGLLAGVV
DSKTTGAANAYGSAMYYSIVYLITTMGTFGVVMLLARRDFEADTLEDFKGLNQRSPVFAFVMMIMMFSLAGIPPAVGFYA
KLAVLQATMNAGLTWLTVLAVITSLFGAFYYLRIVKLMYFDDPQDKSPILADTSTRALLAFNGVAVLVLGIVPDPLLKAC
LQAIQHTLLL

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831108, Length=327, Percent_Identity=23.5474006116208, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI145693160, Length=492, Percent_Identity=32.9268292682927, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI1788614, Length=399, Percent_Identity=22.8070175438596, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788831, Length=369, Percent_Identity=24.1192411924119, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788827, Length=333, Percent_Identity=26.7267267267267, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1788613, Length=432, Percent_Identity=25.6944444444444, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI2367154, Length=268, Percent_Identity=24.6268656716418, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 53380; Mature: 53380

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA