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The map label for this gene is kdpE [H]

Identifier: 91782580

GI number: 91782580

Start: 1348615

End: 1349313

Strand: Direct

Name: kdpE [H]

Synonym: Bxe_A3248

Alternate gene names: 91782580

Gene position: 1348615-1349313 (Clockwise)

Preceding gene: 91782579

Following gene: 91782581

Centisome position: 27.55

GC content: 66.81

Gene sequence:

>699_bases
ATGACTGACCCCAGCATCACCGTCGTCCTGATCGAGGACGAAAAGCAGATTCGCCGCTTTGTGCGAACGGCGCTGGAAGG
CGAGGGCATCGTCGTGCACGACGCCGAAACCGGCAAGCAGGGTCTCGTCGAAGCCGCGACGCGCAAGCCCGATCTGGTGA
TCGTCGATCTCGGCCTGCCCGACACGGACGGTCTGGACGTCATCCGCGAACTGCGCGGCTGGAGCGAGCTGCCGGTAATC
GTGCTGTCGGCGCGCACCCAGGAAACCGAAAAAGTCGCGGCGCTCGATGCCGGCGCGGACGACTACCTCACCAAGCCGTT
CGGCGTGTCCGAACTGCTGGCGCGAATCCGCGCGCATATGCGGCGGCGCAATCAGGGCGGCGCGAACGAATCGCCGCAGG
TGCGCTTCGGCACGGTGACCGTCGATCTGGCGTTGCGCCAGGTGAGCCGCGACGGCGCGGCCGTCCATCTGACGCCGATC
GAATACCGGCTGCTCGCCACGCTGGTGCGCCATGCAGGCCGCGTGCTGACACACCGCCAGTTGCTGCGCGAGGTGTGGGG
GCCGTCGCATGTCGAGAGCCATCACTATCTGCGCATCTATATGGCGCATCTACGCGGCAAGCTGGAGCGCGACCCGGCGC
AGCCGGAACATATCATCACGGAAACCGGGGTCGGCTACCGGCTGGTCGGCGCGGTCTGA

Upstream 100 bases:

>100_bases
CCCGAGGCACCGGATGCACTGGAAGACGAAGGCGCCGATGCCTTGACGCATGTCGATACCGACAGCGAATCAACTCCTAA
CCCGTTTGCCAAGCCCAGCC

Downstream 100 bases:

>100_bases
CGCTGGGTGGGGAATTTGCCACGGCCGGCGTGCTCCTGTTGCAGCGAGCCGTCGGCCGCGGCTCTACGGCGATGTGGGTA
TAATTTACGGTTCGTAAGGA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MTDPSITVVLIEDEKQIRRFVRTALEGEGIVVHDAETGKQGLVEAATRKPDLVIVDLGLPDTDGLDVIRELRGWSELPVI
VLSARTQETEKVAALDAGADDYLTKPFGVSELLARIRAHMRRRNQGGANESPQVRFGTVTVDLALRQVSRDGAAVHLTPI
EYRLLATLVRHAGRVLTHRQLLREVWGPSHVESHHYLRIYMAHLRGKLERDPAQPEHIITETGVGYRLVGAV

Sequences:

>Translated_232_residues
MTDPSITVVLIEDEKQIRRFVRTALEGEGIVVHDAETGKQGLVEAATRKPDLVIVDLGLPDTDGLDVIRELRGWSELPVI
VLSARTQETEKVAALDAGADDYLTKPFGVSELLARIRAHMRRRNQGGANESPQVRFGTVTVDLALRQVSRDGAAVHLTPI
EYRLLATLVRHAGRVLTHRQLLREVWGPSHVESHHYLRIYMAHLRGKLERDPAQPEHIITETGVGYRLVGAV
>Mature_231_residues
TDPSITVVLIEDEKQIRRFVRTALEGEGIVVHDAETGKQGLVEAATRKPDLVIVDLGLPDTDGLDVIRELRGWSELPVIV
LSARTQETEKVAALDAGADDYLTKPFGVSELLARIRAHMRRRNQGGANESPQVRFGTVTVDLALRQVSRDGAAVHLTPIE
YRLLATLVRHAGRVLTHRQLLREVWGPSHVESHHYLRIYMAHLRGKLERDPAQPEHIITETGVGYRLVGAV

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=63.677130044843, Blast_Score=293, Evalue=6e-81,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=37.2727272727273, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=35.7142857142857, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI87082012, Length=226, Percent_Identity=33.6283185840708, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=35.1111111111111, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=32.7510917030568, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=37.219730941704, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1790552, Length=226, Percent_Identity=34.9557522123894, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1789809, Length=235, Percent_Identity=31.9148936170213, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI2367329, Length=233, Percent_Identity=33.0472103004292, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=32.4444444444444, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=29.6943231441048, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=29.3103448275862, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=28.82096069869, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=34.9056603773585, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1790299, Length=122, Percent_Identity=31.9672131147541, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788191, Length=116, Percent_Identity=31.8965517241379, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI48994928, Length=117, Percent_Identity=37.6068376068376, Blast_Score=61, Evalue=5e-11,
Organism=Escherichia coli, GI1790437, Length=143, Percent_Identity=28.6713286713287, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25802; Mature: 25671

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDPSITVVLIEDEKQIRRFVRTALEGEGIVVHDAETGKQGLVEAATRKPDLVIVDLGLP
CCCCCEEEEEECCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHCCCCCEEEEECCCC
DTDGLDVIRELRGWSELPVIVLSARTQETEKVAALDAGADDYLTKPFGVSELLARIRAHM
CCCHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHHH
RRRNQGGANESPQVRFGTVTVDLALRQVSRDGAAVHLTPIEYRLLATLVRHAGRVLTHRQ
HHHCCCCCCCCCCEEEEEEEHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHH
LLREVWGPSHVESHHYLRIYMAHLRGKLERDPAQPEHIITETGVGYRLVGAV
HHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCEEEECCC
>Mature Secondary Structure 
TDPSITVVLIEDEKQIRRFVRTALEGEGIVVHDAETGKQGLVEAATRKPDLVIVDLGLP
CCCCEEEEEECCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHCCCCCEEEEECCCC
DTDGLDVIRELRGWSELPVIVLSARTQETEKVAALDAGADDYLTKPFGVSELLARIRAHM
CCCHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHHH
RRRNQGGANESPQVRFGTVTVDLALRQVSRDGAAVHLTPIEYRLLATLVRHAGRVLTHRQ
HHHCCCCCCCCCCEEEEEEEHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHH
LLREVWGPSHVESHHYLRIYMAHLRGKLERDPAQPEHIITETGVGYRLVGAV
HHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]