BacMap

Definition	Burkholderia xenovorans LB400 chromosome 1, complete sequence.
Accession	NC_007951
Length	4,895,836

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The map label for this gene is fhuC [H]

Identifier: 91782331

GI number: 91782331

Start: 1062095

End: 1062934

Strand: Direct

Name: fhuC [H]

Synonym: Bxe_A3500

Alternate gene names: 91782331

Gene position: 1062095-1062934 (Clockwise)

Preceding gene: 91782330

Following gene: 91782332

Centisome position: 21.69

GC content: 68.57

Gene sequence:

>840_bases
ATGATGCCGAGCTTCGAACCTTCCCGGGCTGTCCTCAGCGCGCAACGTCTGACTTTGCGTGCCGGCGCGCGCACCTTGCT
CGATGCATTCACGCATACGTTCTACGCAGGCGAGATCTGGTGCGTGGCCGGCCCGAACGGCGCGGGCAAGACCACCTTGC
TCTCCACGCTGGCGGGTCTGTTGCAACCGTCGGCGGGCCATGTCGAACTCGACGGCGTGCGCGTGGCCGACTGGCCGCCG
CTCGCGCTCGCGCAGCGCCGCGCGTTGATGCCGCAAAGCGCGCCGGACGCATTCAGCGCGAGCGTGTTCGATATCGTGAT
GCTGAACCGCTTTCCGCATCTCGGCGGCTGGGGCTGGGAGCGTGAGGCCGATCGCGAGGCGGCGCATGCGGCCCTGGACC
AGCTGGGCCTCGCCGCATTTGCCGCGCGCGATGTGCTGTCGCTCTCCGGCGGCGAGCGTCAGCGCGTGGCGCTCGCGGCG
GCGCTATGCCAGGACGCGCCGTTGCTGCTGCTCGACGAACCGTTGTCGCATCTCGATCTGCATCATCAGATCGACTGTCT
CGAAGCGCTCGCCGCGTGGACGCGCGAGCCTCGGCGTACCGTGATGTTTTCGTGCCACGACCTGAACCTCGCGCGCCGCT
TTGCGACGCATGCGCTGCTGCTCGACGGCGCGGGCGGCGCCTACGCCGGACCCGTCCACGACGTGCTGACGCCCACGCTC
GCCAGCCGGGCTTTTGGCTACCCTTTGATCCTGATTCGCGACGGCGAACACGAGGCACTGATTCCCGCGCCGCGTACGCG
TCACGAATCTGCTGCCGGTCATGACACGCCGGCAGGCTGA

Upstream 100 bases:

>100_bases
TCGCGCGCACCGTGATCGCGCCGGCGCAGTTGCCGGTCGGCGTGATCACGTCGATCATCGGCGTGCCGGTGTTTCTGTGG
ATGCTCTTGCGCAGACGCCG

Downstream 100 bases:

>100_bases
TCGTTTCATCTCAACACTCTCTTTGCAGACACCTTTATGACTTCATCGCCACGCTTGCCCGGACTGCCCGAAGTCGAACC
GCTCGATCAAACGCTGCGTG

Product: ABC Fe3+-hydroxamate/cobalamin transporter, ATPase subunit

Products: NA

Alternate protein names: Ferric hydroxamate uptake protein C; Ferrichrome transport ATP-binding protein FhuC; Iron(III)-hydroxamate import ATP-binding protein FhuC [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MMPSFEPSRAVLSAQRLTLRAGARTLLDAFTHTFYAGEIWCVAGPNGAGKTTLLSTLAGLLQPSAGHVELDGVRVADWPP
LALAQRRALMPQSAPDAFSASVFDIVMLNRFPHLGGWGWEREADREAAHAALDQLGLAAFAARDVLSLSGGERQRVALAA
ALCQDAPLLLLDEPLSHLDLHHQIDCLEALAAWTREPRRTVMFSCHDLNLARRFATHALLLDGAGGAYAGPVHDVLTPTL
ASRAFGYPLILIRDGEHEALIPAPRTRHESAAGHDTPAG

Sequences:

>Translated_279_residues
MMPSFEPSRAVLSAQRLTLRAGARTLLDAFTHTFYAGEIWCVAGPNGAGKTTLLSTLAGLLQPSAGHVELDGVRVADWPP
LALAQRRALMPQSAPDAFSASVFDIVMLNRFPHLGGWGWEREADREAAHAALDQLGLAAFAARDVLSLSGGERQRVALAA
ALCQDAPLLLLDEPLSHLDLHHQIDCLEALAAWTREPRRTVMFSCHDLNLARRFATHALLLDGAGGAYAGPVHDVLTPTL
ASRAFGYPLILIRDGEHEALIPAPRTRHESAAGHDTPAG
>Mature_279_residues
MMPSFEPSRAVLSAQRLTLRAGARTLLDAFTHTFYAGEIWCVAGPNGAGKTTLLSTLAGLLQPSAGHVELDGVRVADWPP
LALAQRRALMPQSAPDAFSASVFDIVMLNRFPHLGGWGWEREADREAAHAALDQLGLAAFAARDVLSLSGGERQRVALAA
ALCQDAPLLLLDEPLSHLDLHHQIDCLEALAAWTREPRRTVMFSCHDLNLARRFATHALLLDGAGGAYAGPVHDVLTPTL
ASRAFGYPLILIRDGEHEALIPAPRTRHESAAGHDTPAG

Specific function: Part of the ABC transporter complex FhuBGCD involved in iron(3+)-hydroxamate import. Responsible for energy coupling to the transport system [H]

COG id: COG1120

COG function: function code PH; ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI9665248, Length=222, Percent_Identity=30.1801801801802, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI73747915, Length=210, Percent_Identity=29.0476190476191, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI46592956, Length=165, Percent_Identity=32.7272727272727, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI46592971, Length=165, Percent_Identity=32.7272727272727, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI46592978, Length=165, Percent_Identity=32.7272727272727, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI46592915, Length=165, Percent_Identity=32.7272727272727, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI46592898, Length=165, Percent_Identity=32.7272727272727, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI46592964, Length=165, Percent_Identity=32.1212121212121, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI105990541, Length=229, Percent_Identity=31.0043668122271, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI171184400, Length=207, Percent_Identity=28.5024154589372, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI27881501, Length=259, Percent_Identity=24.7104247104247, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI30795238, Length=259, Percent_Identity=24.7104247104247, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI156105685, Length=221, Percent_Identity=31.2217194570136, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI31657092, Length=233, Percent_Identity=25.3218884120172, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1786803, Length=247, Percent_Identity=36.4372469635627, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI1786345, Length=242, Percent_Identity=35.5371900826446, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1790739, Length=254, Percent_Identity=32.2834645669291, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1786253, Length=210, Percent_Identity=33.3333333333333, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788002, Length=244, Percent_Identity=34.8360655737705, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI87081709, Length=225, Percent_Identity=29.7777777777778, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI87081791, Length=177, Percent_Identity=36.7231638418079, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1789032, Length=226, Percent_Identity=29.2035398230088, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786563, Length=211, Percent_Identity=32.2274881516588, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1786872, Length=181, Percent_Identity=33.1491712707182, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1786698, Length=201, Percent_Identity=29.3532338308458, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1788225, Length=222, Percent_Identity=29.2792792792793, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790544, Length=241, Percent_Identity=27.3858921161826, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI87082267, Length=208, Percent_Identity=29.3269230769231, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787712, Length=186, Percent_Identity=32.258064516129, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1789873, Length=207, Percent_Identity=31.8840579710145, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1787112, Length=197, Percent_Identity=32.994923857868, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1790467, Length=231, Percent_Identity=28.5714285714286, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1787029, Length=208, Percent_Identity=30.2884615384615, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788450, Length=241, Percent_Identity=28.2157676348548, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787370, Length=185, Percent_Identity=32.4324324324324, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1788761, Length=210, Percent_Identity=30.952380952381, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1788165, Length=214, Percent_Identity=27.5700934579439, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787041, Length=188, Percent_Identity=30.3191489361702, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1786703, Length=199, Percent_Identity=33.1658291457286, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87081834, Length=205, Percent_Identity=31.7073170731707, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788506, Length=253, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787164, Length=188, Percent_Identity=38.2978723404255, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789593, Length=204, Percent_Identity=30.8823529411765, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081782, Length=173, Percent_Identity=31.2138728323699, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788210, Length=233, Percent_Identity=27.8969957081545, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787143, Length=196, Percent_Identity=27.0408163265306, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87082268, Length=222, Percent_Identity=27.027027027027, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787182, Length=240, Percent_Identity=28.75, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1789864, Length=216, Percent_Identity=25, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786319, Length=146, Percent_Identity=30.1369863013699, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789962, Length=198, Percent_Identity=25.2525252525253, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1789751, Length=209, Percent_Identity=28.2296650717703, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788053, Length=174, Percent_Identity=34.4827586206897, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788644, Length=255, Percent_Identity=27.4509803921569, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1786653, Length=248, Percent_Identity=27.8225806451613, Blast_Score=61, Evalue=7e-11,
Organism=Escherichia coli, GI1787105, Length=196, Percent_Identity=29.5918367346939, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17565938, Length=231, Percent_Identity=26.8398268398268, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI115533592, Length=195, Percent_Identity=30.7692307692308, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71992290, Length=224, Percent_Identity=26.7857142857143, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17558664, Length=178, Percent_Identity=30.3370786516854, Blast_Score=67, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6320296, Length=198, Percent_Identity=27.7777777777778, Blast_Score=76, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24641565, Length=227, Percent_Identity=28.1938325991189, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281362751, Length=206, Percent_Identity=29.126213592233, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24650853, Length=206, Percent_Identity=29.126213592233, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24650855, Length=206, Percent_Identity=29.126213592233, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648314, Length=168, Percent_Identity=29.7619047619048, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI85726357, Length=200, Percent_Identity=28, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: =3.6.3.34 [H]

Molecular weight: Translated: 29928; Mature: 29928

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMPSFEPSRAVLSAQRLTLRAGARTLLDAFTHTFYAGEIWCVAGPNGAGKTTLLSTLAGL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCEEEEEECCCCCCHHHHHHHHHHH
LQPSAGHVELDGVRVADWPPLALAQRRALMPQSAPDAFSASVFDIVMLNRFPHLGGWGWE
HCCCCCCEEECCEEECCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
READREAAHAALDQLGLAAFAARDVLSLSGGERQRVALAAALCQDAPLLLLDEPLSHLDL
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEECCCHHHHHH
HHQIDCLEALAAWTREPRRTVMFSCHDLNLARRFATHALLLDGAGGAYAGPVHDVLTPTL
HHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHH
ASRAFGYPLILIRDGEHEALIPAPRTRHESAAGHDTPAG
HHHHCCCEEEEEECCCCCEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MMPSFEPSRAVLSAQRLTLRAGARTLLDAFTHTFYAGEIWCVAGPNGAGKTTLLSTLAGL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCEEEEEECCCCCCHHHHHHHHHHH
LQPSAGHVELDGVRVADWPPLALAQRRALMPQSAPDAFSASVFDIVMLNRFPHLGGWGWE
HCCCCCCEEECCEEECCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
READREAAHAALDQLGLAAFAARDVLSLSGGERQRVALAAALCQDAPLLLLDEPLSHLDL
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEECCCHHHHHH
HHQIDCLEALAAWTREPRRTVMFSCHDLNLARRFATHALLLDGAGGAYAGPVHDVLTPTL
HHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHH
ASRAFGYPLILIRDGEHEALIPAPRTRHESAAGHDTPAG
HHHHCCCEEEEEECCCCCEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]