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The map label for this gene is btuC [H]

Identifier: 91782330

GI number: 91782330

Start: 1061088

End: 1062098

Strand: Direct

Name: btuC [H]

Synonym: Bxe_A3501

Alternate gene names: 91782330

Gene position: 1061088-1062098 (Clockwise)

Preceding gene: 91782329

Following gene: 91782331

Centisome position: 21.67

GC content: 72.8

Gene sequence:

>1011_bases
ATGAGCGCGAAGCGCGCGGCCGCGATCTGGCTCGCGCTCGCTGTCATCGCGCTGGCCGTGCTGATGGCGTCGCTCGCGCT
GGGCAGCGTATCGCTCGCGCCGCTGCGCGTGCTGGCGGCGCTGGTGCCAGCGCATGGGCCGTCTGCCGGCTCCTCTGATC
TGACTGCCGAGATCGTGCGCACGCTGCGTTTGCCGCGCGCGGTGGCCGGCTTTGCGTGCGGCGCGTTGCTCGCATTGGCG
GGCGCGCTGCTGCAGGTGCTGTTGCGCAATCCGCTCGCCGAACCCTACGTGCTGGGTGTGTCGGGCGGCGCGGCCAGCTT
CGCGCTCGTCGCGATGATCGCCGGCTGCGCCTGGTGGATGGTCGACGCGAGCGCCTTCGCCGGCGCCTTCGCGTCGATCC
TGCTGGTGCTCGGCCTCGCGCGCCGCGAGTTGTGGCGCGGCGAGCCGCAGGACACGTCGCCACGTCTGCTGCTGACGGGC
GCGGTGATCGCCGCGGGCTGGGGCGCGCTCATCACCTTGCTGCTCAACCTCGCGCCGGACAACCGTCTGCGCGGCATGCT
GTTCTGGCTGACCGGCGACCTCAACGGCGGCGCGATGCCGTGGACGGCGCTCGCCGCGCTGGTCGTCGCGCTGGCGGCGA
TCGTGCCGGCCGCGCCGCGTCTGAACGTGCTGCTGCGTGGCGACGCCGCCGCGCAGGCGTTGGGCGTGGCGGTGATGCCG
TTGCGCTTGCGCGTGTATCTGGTGGCTTCGCTGGCGGCGGCCGCGGCGGTGACGACGGCGGGCACCATCGGCTTTGTCGG
GCTGGTCGTGCCGCATATGCTGCGGCTCGCGTTCGGCAACGATCAGCGCATGCTGCTGCCGGCCGCCGCGCTCGGCGGCG
GCGTCGCCGTGATGGGCGCGGACCTGATCGCGCGCACCGTGATCGCGCCGGCGCAGTTGCCGGTCGGCGTGATCACGTCG
ATCATCGGCGTGCCGGTGTTTCTGTGGATGCTCTTGCGCAGACGCCGATGA

Upstream 100 bases:

>100_bases
GAGCCGACTTATGAGCCAACCCGCGAGCCAACCCACGAGCCCACAAGCGAGCCCACAAGCGACCCGCCACCCCGGCCCGA
TACCCGCGACGCTGCGCGTG

Downstream 100 bases:

>100_bases
TGCCGAGCTTCGAACCTTCCCGGGCTGTCCTCAGCGCGCAACGTCTGACTTTGCGTGCCGGCGCGCGCACCTTGCTCGAT
GCATTCACGCATACGTTCTA

Product: ABC Fe3+-hydroxamate/cobalamin transporter, inner membrane subunit

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MSAKRAAAIWLALAVIALAVLMASLALGSVSLAPLRVLAALVPAHGPSAGSSDLTAEIVRTLRLPRAVAGFACGALLALA
GALLQVLLRNPLAEPYVLGVSGGAASFALVAMIAGCAWWMVDASAFAGAFASILLVLGLARRELWRGEPQDTSPRLLLTG
AVIAAGWGALITLLLNLAPDNRLRGMLFWLTGDLNGGAMPWTALAALVVALAAIVPAAPRLNVLLRGDAAAQALGVAVMP
LRLRVYLVASLAAAAAVTTAGTIGFVGLVVPHMLRLAFGNDQRMLLPAAALGGGVAVMGADLIARTVIAPAQLPVGVITS
IIGVPVFLWMLLRRRR

Sequences:

>Translated_336_residues
MSAKRAAAIWLALAVIALAVLMASLALGSVSLAPLRVLAALVPAHGPSAGSSDLTAEIVRTLRLPRAVAGFACGALLALA
GALLQVLLRNPLAEPYVLGVSGGAASFALVAMIAGCAWWMVDASAFAGAFASILLVLGLARRELWRGEPQDTSPRLLLTG
AVIAAGWGALITLLLNLAPDNRLRGMLFWLTGDLNGGAMPWTALAALVVALAAIVPAAPRLNVLLRGDAAAQALGVAVMP
LRLRVYLVASLAAAAAVTTAGTIGFVGLVVPHMLRLAFGNDQRMLLPAAALGGGVAVMGADLIARTVIAPAQLPVGVITS
IIGVPVFLWMLLRRRR
>Mature_335_residues
SAKRAAAIWLALAVIALAVLMASLALGSVSLAPLRVLAALVPAHGPSAGSSDLTAEIVRTLRLPRAVAGFACGALLALAG
ALLQVLLRNPLAEPYVLGVSGGAASFALVAMIAGCAWWMVDASAFAGAFASILLVLGLARRELWRGEPQDTSPRLLLTGA
VIAAGWGALITLLLNLAPDNRLRGMLFWLTGDLNGGAMPWTALAALVVALAAIVPAAPRLNVLLRGDAAAQALGVAVMPL
RLRVYLVASLAAAAAVTTAGTIGFVGLVVPHMLRLAFGNDQRMLLPAAALGGGVAVMGADLIARTVIAPAQLPVGVITSI
IGVPVFLWMLLRRRR

Specific function: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=282, Percent_Identity=37.2340425531915, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1788004, Length=284, Percent_Identity=37.6760563380282, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI1790741, Length=302, Percent_Identity=35.7615894039735, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1786347, Length=300, Percent_Identity=31.6666666666667, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1786805, Length=320, Percent_Identity=36.25, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1786804, Length=313, Percent_Identity=37.6996805111821, Blast_Score=82, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 34343; Mature: 34212

Theoretical pI: Translated: 12.05; Mature: 12.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAKRAAAIWLALAVIALAVLMASLALGSVSLAPLRVLAALVPAHGPSAGSSDLTAEIVR
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
TLRLPRAVAGFACGALLALAGALLQVLLRNPLAEPYVLGVSGGAASFALVAMIAGCAWWM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
VDASAFAGAFASILLVLGLARRELWRGEPQDTSPRLLLTGAVIAAGWGALITLLLNLAPD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCC
NRLRGMLFWLTGDLNGGAMPWTALAALVVALAAIVPAAPRLNVLLRGDAAAQALGVAVMP
CCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHH
LRLRVYLVASLAAAAAVTTAGTIGFVGLVVPHMLRLAFGNDQRMLLPAAALGGGVAVMGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHCCCHHHHHH
DLIARTVIAPAQLPVGVITSIIGVPVFLWMLLRRRR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SAKRAAAIWLALAVIALAVLMASLALGSVSLAPLRVLAALVPAHGPSAGSSDLTAEIVR
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
TLRLPRAVAGFACGALLALAGALLQVLLRNPLAEPYVLGVSGGAASFALVAMIAGCAWWM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
VDASAFAGAFASILLVLGLARRELWRGEPQDTSPRLLLTGAVIAAGWGALITLLLNLAPD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCC
NRLRGMLFWLTGDLNGGAMPWTALAALVVALAAIVPAAPRLNVLLRGDAAAQALGVAVMP
CCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHH
LRLRVYLVASLAAAAAVTTAGTIGFVGLVVPHMLRLAFGNDQRMLLPAAALGGGVAVMGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHCCCHHHHHH
DLIARTVIAPAQLPVGVITSIIGVPVFLWMLLRRRR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA