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The map label for this gene is pamO [H]

Identifier: 91782247

GI number: 91782247

Start: 969173

End: 970795

Strand: Direct

Name: pamO [H]

Synonym: Bxe_A3588

Alternate gene names: 91782247

Gene position: 969173-970795 (Clockwise)

Preceding gene: 91782246

Following gene: 91782248

Centisome position: 19.8

GC content: 56.69

Gene sequence:

>1623_bases
ATGAATAACGTTTCGCAATCGCACTTCGATGCAGTGATCATTGGCGCCGGATTCGGCGGAATGTATGCGATTTTCAAGCT
TCGCGCAACAGGCATGTCCGTTCGCGCGTTCGAAGCGGGAACCGACGTAGGCGGCACCTGGTACTGGAATCGCTATCCTG
GCGCGCGTTGCGACGTGGAGAGCATCGAGTATTCGTATTCATTTTCCGAGGAGCTGCAACAGGAATGGTCTTGGAGCGAG
CGCTATGCATCACAGCCGGAAATTCTTCGCTACGCTGGGCATGTTGCAGACCGCTTCGGCCTGCGCGAGGACATCCGTTT
CAACCAGCGCGTTCTCACTGCGGAATTCGATCCCGCGGTAAATCTCTGGACAGTGAGAACGGACAAAGGAGAGGTGGCGA
CCGCCCAGTTCCTAATTACCGCTGCGGGTTGTCTTTCGGTTCCACGCATGCCGGACATTCCGGGACGCGACGACTTCGGG
GGCAATCTTTATCACACGGGCGCATGGCCACATGAAGGTGTCGACTTTACGGGGCGTCGCGTTGGCGTGATTGGCACGGG
CTCGTCGGGCATCCAGGTGATTCCGCAGATTGCCAAAGCAGCCGCGCATTGCACAGTTTTCCAGCGCACTCCGAACTTCA
GCCTCGCTGCTTATAACAAGCCCATGGATCCGGACCTAGCGCGCGAATACAAACAGAACTACGCGACGCATCGTGCGAAA
GCGCGTCACGCAGCCGCCGGCATTGCGAGCCATCCGACGCCGGAAAAGGGCGCATTCGACGATTCACCGTCAGAGCGGGA
AAAGCTCTATGAAATCGGGTGGAACTGGGGCAACACGGGCTTCACTCGCATTTACAAGGATATTCTTTCGAACCTTGAAG
CGAATGACACTATGGCGGACTTCGTGCGGAGAAAGATCCGCGACATGGTGAAGAATCCCGATGTCGCAGCAATGCTGACG
CCGAATGACCATCCAATCGGAACCAAGCGAATCTGTCTTGATACCGACTACTTCGAAACATACAACCGTGACAACGTTTC
TCTCGTCGACGTCCGCAAGCATCCAATCACGAGCATTTCGCGTGAAGGTATTCATACCGACAATGAAGCGTATCCACTCG
ATGCCATCGTGTTCGCGACCGGCTACGACGCGGTAACGGGCGCTATTCTCGGCATCGATATTCGCGTGAAGGGGCGGCAG
GAATCACTGGCGGAAAAGTGGAGCGCGGGACCGCGAACGTATCTGGGTCTGATGACAGCGGGATTCCCCAATCTGTTTTT
CATCACCGGGCCGGGCAGTCCGTCGGTGTTGACCAACATGATTTCGTCGATCGAGCAACACGTCGAATGGATCGCGGAAT
GTTTGCAGTACCTTCGTTCCAGCAGTGTGCATCGCATGGAGGCCCAACTGAACTCTGAGGATGCATGGGTCACCCACGTC
AATGAAGTCGCGGATACGACGTTGTTCCCGCGCGCTGCTTCGTGGTATATAGGGGCGAACATTCCGGGCAAGCCGAGGGT
GTTTCTCCCGTATGTGGGCGGGCTGGGCCGATACCGTGCTAGGTGTGACGAGGTGGCGCGCCGCGGTTACGAAGGTTTCT
CGCTGGATGAAACGGCTGCATAA

Upstream 100 bases:

>100_bases
TTCCTGTCCGCGGAGCCAGTTAGGAACAGATCAAACGGGTAGAACGACACGATCGGGCAACTGCTCAATCCATCGAACTC
ATCGTCAACGGAAACCTGTC

Downstream 100 bases:

>100_bases
CGCACAAACAGATAACCGACAGAAGGATAGCGATGCAAAAACGTCTGCTTGTTACAATTGGATTGGTTCTCGTCACACCC
GCGCTTTGCGTCTTCAGTCC

Product: cyclohexanone monooxygenase

Products: NA

Alternate protein names: PAMO; Baeyer-Villiger monooxygenase; BVMO [H]

Number of amino acids: Translated: 540; Mature: 540

Protein sequence:

>540_residues
MNNVSQSHFDAVIIGAGFGGMYAIFKLRATGMSVRAFEAGTDVGGTWYWNRYPGARCDVESIEYSYSFSEELQQEWSWSE
RYASQPEILRYAGHVADRFGLREDIRFNQRVLTAEFDPAVNLWTVRTDKGEVATAQFLITAAGCLSVPRMPDIPGRDDFG
GNLYHTGAWPHEGVDFTGRRVGVIGTGSSGIQVIPQIAKAAAHCTVFQRTPNFSLAAYNKPMDPDLAREYKQNYATHRAK
ARHAAAGIASHPTPEKGAFDDSPSEREKLYEIGWNWGNTGFTRIYKDILSNLEANDTMADFVRRKIRDMVKNPDVAAMLT
PNDHPIGTKRICLDTDYFETYNRDNVSLVDVRKHPITSISREGIHTDNEAYPLDAIVFATGYDAVTGAILGIDIRVKGRQ
ESLAEKWSAGPRTYLGLMTAGFPNLFFITGPGSPSVLTNMISSIEQHVEWIAECLQYLRSSSVHRMEAQLNSEDAWVTHV
NEVADTTLFPRAASWYIGANIPGKPRVFLPYVGGLGRYRARCDEVARRGYEGFSLDETAA

Sequences:

>Translated_540_residues
MNNVSQSHFDAVIIGAGFGGMYAIFKLRATGMSVRAFEAGTDVGGTWYWNRYPGARCDVESIEYSYSFSEELQQEWSWSE
RYASQPEILRYAGHVADRFGLREDIRFNQRVLTAEFDPAVNLWTVRTDKGEVATAQFLITAAGCLSVPRMPDIPGRDDFG
GNLYHTGAWPHEGVDFTGRRVGVIGTGSSGIQVIPQIAKAAAHCTVFQRTPNFSLAAYNKPMDPDLAREYKQNYATHRAK
ARHAAAGIASHPTPEKGAFDDSPSEREKLYEIGWNWGNTGFTRIYKDILSNLEANDTMADFVRRKIRDMVKNPDVAAMLT
PNDHPIGTKRICLDTDYFETYNRDNVSLVDVRKHPITSISREGIHTDNEAYPLDAIVFATGYDAVTGAILGIDIRVKGRQ
ESLAEKWSAGPRTYLGLMTAGFPNLFFITGPGSPSVLTNMISSIEQHVEWIAECLQYLRSSSVHRMEAQLNSEDAWVTHV
NEVADTTLFPRAASWYIGANIPGKPRVFLPYVGGLGRYRARCDEVARRGYEGFSLDETAA
>Mature_540_residues
MNNVSQSHFDAVIIGAGFGGMYAIFKLRATGMSVRAFEAGTDVGGTWYWNRYPGARCDVESIEYSYSFSEELQQEWSWSE
RYASQPEILRYAGHVADRFGLREDIRFNQRVLTAEFDPAVNLWTVRTDKGEVATAQFLITAAGCLSVPRMPDIPGRDDFG
GNLYHTGAWPHEGVDFTGRRVGVIGTGSSGIQVIPQIAKAAAHCTVFQRTPNFSLAAYNKPMDPDLAREYKQNYATHRAK
ARHAAAGIASHPTPEKGAFDDSPSEREKLYEIGWNWGNTGFTRIYKDILSNLEANDTMADFVRRKIRDMVKNPDVAAMLT
PNDHPIGTKRICLDTDYFETYNRDNVSLVDVRKHPITSISREGIHTDNEAYPLDAIVFATGYDAVTGAILGIDIRVKGRQ
ESLAEKWSAGPRTYLGLMTAGFPNLFFITGPGSPSVLTNMISSIEQHVEWIAECLQYLRSSSVHRMEAQLNSEDAWVTHV
NEVADTTLFPRAASWYIGANIPGKPRVFLPYVGGLGRYRARCDEVARRGYEGFSLDETAA

Specific function: Catalyzes a Baeyer-Villiger oxidation reaction, i.e., the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters. Is most efficient with phenylacetone as substrate, leading to the formation of benzyl

COG id: COG2072

COG function: function code P; Predicted flavoprotein involved in K+ transport

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-binding monooxygenase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI25145785, Length=244, Percent_Identity=24.1803278688525, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19921694, Length=241, Percent_Identity=25.3112033195021, Blast_Score=78, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020946 [H]

Pfam domain/function: PF00743 FMO-like [H]

EC number: =1.14.13.92 [H]

Molecular weight: Translated: 60133; Mature: 60133

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNVSQSHFDAVIIGAGFGGMYAIFKLRATGMSVRAFEAGTDVGGTWYWNRYPGARCDVE
CCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCEEEEEECCCCCCCEEEECCCCCCCCCHH
SIEYSYSFSEELQQEWSWSERYASQPEILRYAGHVADRFGLREDIRFNQRVLTAEFDPAV
HHEECCCHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHCCHHHCCCCCEEEEEECCCCE
NLWTVRTDKGEVATAQFLITAAGCLSVPRMPDIPGRDDFGGNLYHTGAWPHEGVDFTGRR
EEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCE
VGVIGTGSSGIQVIPQIAKAAAHCTVFQRTPNFSLAAYNKPMDPDLAREYKQNYATHRAK
EEEEECCCCCHHHHHHHHHHHHHEEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHH
ARHAAAGIASHPTPEKGAFDDSPSEREKLYEIGWNWGNTGFTRIYKDILSNLEANDTMAD
HHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHH
FVRRKIRDMVKNPDVAAMLTPNDHPIGTKRICLDTDYFETYNRDNVSLVDVRKHPITSIS
HHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEECHHHHHCCCCCEEEEEECCCCCCHHH
REGIHTDNEAYPLDAIVFATGYDAVTGAILGIDIRVKGRQESLAEKWSAGPRTYLGLMTA
HCCCCCCCCCCCCEEEEEECCCHHHHCEEEEEEEEECCCHHHHHHHHCCCCHHHHHHHHC
GFPNLFFITGPGSPSVLTNMISSIEQHVEWIAECLQYLRSSSVHRMEAQLNSEDAWVTHV
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHCCCCCHHHHHH
NEVADTTLFPRAASWYIGANIPGKPRVFLPYVGGLGRYRARCDEVARRGYEGFSLDETAA
HHHHHHHCCCCCCCEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MNNVSQSHFDAVIIGAGFGGMYAIFKLRATGMSVRAFEAGTDVGGTWYWNRYPGARCDVE
CCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCEEEEEECCCCCCCEEEECCCCCCCCCHH
SIEYSYSFSEELQQEWSWSERYASQPEILRYAGHVADRFGLREDIRFNQRVLTAEFDPAV
HHEECCCHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHCCHHHCCCCCEEEEEECCCCE
NLWTVRTDKGEVATAQFLITAAGCLSVPRMPDIPGRDDFGGNLYHTGAWPHEGVDFTGRR
EEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCE
VGVIGTGSSGIQVIPQIAKAAAHCTVFQRTPNFSLAAYNKPMDPDLAREYKQNYATHRAK
EEEEECCCCCHHHHHHHHHHHHHEEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHH
ARHAAAGIASHPTPEKGAFDDSPSEREKLYEIGWNWGNTGFTRIYKDILSNLEANDTMAD
HHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHH
FVRRKIRDMVKNPDVAAMLTPNDHPIGTKRICLDTDYFETYNRDNVSLVDVRKHPITSIS
HHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEECHHHHHCCCCCEEEEEECCCCCCHHH
REGIHTDNEAYPLDAIVFATGYDAVTGAILGIDIRVKGRQESLAEKWSAGPRTYLGLMTA
HCCCCCCCCCCCCEEEEEECCCHHHHCEEEEEEEEECCCHHHHHHHHCCCCHHHHHHHHC
GFPNLFFITGPGSPSVLTNMISSIEQHVEWIAECLQYLRSSSVHRMEAQLNSEDAWVTHV
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHCCCCCHHHHHH
NEVADTTLFPRAASWYIGANIPGKPRVFLPYVGGLGRYRARCDEVARRGYEGFSLDETAA
HHHHHHHCCCCCCCEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA