BacMap

Definition	Burkholderia xenovorans LB400 chromosome 1, complete sequence.
Accession	NC_007951
Length	4,895,836

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The map label for this gene is fabG [H]

Identifier: 91782246

GI number: 91782246

Start: 968355

End: 969095

Strand: Direct

Name: fabG [H]

Synonym: Bxe_A3589

Alternate gene names: 91782246

Gene position: 968355-969095 (Clockwise)

Preceding gene: 91782239

Following gene: 91782247

Centisome position: 19.78

GC content: 59.38

Gene sequence:

>741_bases
ATGATCGTGACGGAAGAAAAGGGCGCGTTGCCGCCGGACTTATCGCGCGCCAGAACGGTAATCGTCACGGGAGCGGCTGG
TACGCTGGGCCGGGCCGTTGCCAAAGCATTCGGCGGTGTGGGCGCGAATCTGGTGCTGATCGATCGCGAGGAAAGCGCGT
TGCGCAGCGCGTTCGATAACGCAGGCGAGAACATGCTGTTATGCGCAGCGCGGCTGGATGAGCCCGCTGCGGCGATACCT
GTCGTTGAGCAGGCGGTCGAACGATTCGGCGCGATAGACGTGCTATGCAACGTCGCAGGCGGATTTTACGCAGGCGATTG
CGTGCACGAAATGCGCGATGAAACCTGGGATCTATTGACGAATACGAATGCTCGCACCGTATTGCATATGGCACAGGCTG
TCATTCCAAAGATGATCGCCGCCCGGTACGGCAAAGTCATAAACGTTGCTGCTATGGCCGCGCAGGCCGGAATGGCGCAT
ATGGGCGCCTATTGCGCATCGAAAAGCGCCGTGCTTCGGCTGACTGAGGCTATGTCGGCAGAGCTTCGCGGTCATGGCAT
CAACGTGAACTCGGTCATGCCGAGCATCATCGACACTGCGCAGAATCGCAAAGACATGCCGGACGCCGATTTCGCAACCT
GGGTCAGGCCGGTGGATCTCGCCTGCATCATTCTGTTTCTTGCATCCGATGACGCACGCGCAATTCACGGCGCAGGAATT
CCTGTCCGCGGAGCCAGTTAG

Upstream 100 bases:

>100_bases
AAAAACCCTTATGGTCAATTGGTCTTACCGTAACGATAATCGTACTTGGAATTTGCATCGTGTCAACCAAGGATTTCACC
GAAATGCTGAGGAGAGGCAA

Downstream 100 bases:

>100_bases
GAACAGATCAAACGGGTAGAACGACACGATCGGGCAACTGCTCAATCCATCGAACTCATCGTCAACGGAAACCTGTCATG
AATAACGTTTCGCAATCGCA

Product: putative short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MIVTEEKGALPPDLSRARTVIVTGAAGTLGRAVAKAFGGVGANLVLIDREESALRSAFDNAGENMLLCAARLDEPAAAIP
VVEQAVERFGAIDVLCNVAGGFYAGDCVHEMRDETWDLLTNTNARTVLHMAQAVIPKMIAARYGKVINVAAMAAQAGMAH
MGAYCASKSAVLRLTEAMSAELRGHGINVNSVMPSIIDTAQNRKDMPDADFATWVRPVDLACIILFLASDDARAIHGAGI
PVRGAS

Sequences:

>Translated_246_residues
MIVTEEKGALPPDLSRARTVIVTGAAGTLGRAVAKAFGGVGANLVLIDREESALRSAFDNAGENMLLCAARLDEPAAAIP
VVEQAVERFGAIDVLCNVAGGFYAGDCVHEMRDETWDLLTNTNARTVLHMAQAVIPKMIAARYGKVINVAAMAAQAGMAH
MGAYCASKSAVLRLTEAMSAELRGHGINVNSVMPSIIDTAQNRKDMPDADFATWVRPVDLACIILFLASDDARAIHGAGI
PVRGAS
>Mature_246_residues
MIVTEEKGALPPDLSRARTVIVTGAAGTLGRAVAKAFGGVGANLVLIDREESALRSAFDNAGENMLLCAARLDEPAAAIP
VVEQAVERFGAIDVLCNVAGGFYAGDCVHEMRDETWDLLTNTNARTVLHMAQAVIPKMIAARYGKVINVAAMAAQAGMAH
MGAYCASKSAVLRLTEAMSAELRGHGINVNSVMPSIIDTAQNRKDMPDADFATWVRPVDLACIILFLASDDARAIHGAGI
PVRGAS

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI66933014, Length=243, Percent_Identity=28.3950617283951, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI7705925, Length=238, Percent_Identity=28.9915966386555, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI19923817, Length=257, Percent_Identity=24.9027237354086, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI15277342, Length=249, Percent_Identity=27.3092369477912, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI32483357, Length=243, Percent_Identity=26.7489711934156, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI4503817, Length=188, Percent_Identity=27.6595744680851, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI4504505, Length=228, Percent_Identity=27.1929824561404, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI5031737, Length=244, Percent_Identity=27.8688524590164, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI20149619, Length=196, Percent_Identity=28.0612244897959, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI33667109, Length=204, Percent_Identity=28.4313725490196, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI40807363, Length=190, Percent_Identity=27.8947368421053, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787335, Length=236, Percent_Identity=27.9661016949153, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789208, Length=241, Percent_Identity=30.2904564315353, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI87082100, Length=251, Percent_Identity=27.0916334661355, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1790717, Length=246, Percent_Identity=28.4552845528455, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1787820, Length=178, Percent_Identity=24.7191011235955, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI87082160, Length=241, Percent_Identity=24.896265560166, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1789378, Length=235, Percent_Identity=23.4042553191489, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1787526, Length=241, Percent_Identity=23.2365145228216, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786812, Length=247, Percent_Identity=28.7449392712551, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788459, Length=172, Percent_Identity=29.0697674418605, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1787905, Length=239, Percent_Identity=25.5230125523013, Blast_Score=61, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=245, Percent_Identity=30.2040816326531, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71994604, Length=244, Percent_Identity=30.7377049180328, Blast_Score=89, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17560676, Length=246, Percent_Identity=26.4227642276423, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17551412, Length=200, Percent_Identity=28.5, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=250, Percent_Identity=27.6, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=241, Percent_Identity=27.3858921161826, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=201, Percent_Identity=27.8606965174129, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=241, Percent_Identity=28.6307053941909, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=193, Percent_Identity=28.4974093264249, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17561402, Length=255, Percent_Identity=25.8823529411765, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=247, Percent_Identity=27.5303643724696, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=245, Percent_Identity=27.7551020408163, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=239, Percent_Identity=24.2677824267782, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71982365, Length=190, Percent_Identity=28.4210526315789, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=192, Percent_Identity=26.5625, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI193203115, Length=189, Percent_Identity=26.984126984127, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17555706, Length=239, Percent_Identity=26.7782426778243, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=241, Percent_Identity=26.5560165975104, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=209, Percent_Identity=24.8803827751196, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193203117, Length=187, Percent_Identity=26.7379679144385, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=245, Percent_Identity=26.9387755102041, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=240, Percent_Identity=26.6666666666667, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=241, Percent_Identity=27.8008298755187, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=242, Percent_Identity=26.4462809917355, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=238, Percent_Identity=23.9495798319328, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17559104, Length=238, Percent_Identity=23.9495798319328, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=190, Percent_Identity=27.8947368421053, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322861, Length=209, Percent_Identity=28.7081339712919, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28571526, Length=247, Percent_Identity=29.9595141700405, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI23397609, Length=242, Percent_Identity=30.5785123966942, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI21357041, Length=247, Percent_Identity=27.9352226720648, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24644339, Length=245, Percent_Identity=26.9387755102041, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI28574402, Length=190, Percent_Identity=31.0526315789474, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24584744, Length=190, Percent_Identity=31.0526315789474, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI21355319, Length=238, Percent_Identity=24.7899159663866, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24584748, Length=186, Percent_Identity=27.9569892473118, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI161076933, Length=186, Percent_Identity=27.9569892473118, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24639444, Length=240, Percent_Identity=24.5833333333333, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24644337, Length=258, Percent_Identity=27.906976744186, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24643142, Length=193, Percent_Identity=25.3886010362694, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25830; Mature: 25830

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVTEEKGALPPDLSRARTVIVTGAAGTLGRAVAKAFGGVGANLVLIDREESALRSAFDN
CEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHC
AGENMLLCAARLDEPAAAIPVVEQAVERFGAIDVLCNVAGGFYAGDCVHEMRDETWDLLT
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHC
NTNARTVLHMAQAVIPKMIAARYGKVINVAAMAAQAGMAHMGAYCASKSAVLRLTEAMSA
CCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ELRGHGINVNSVMPSIIDTAQNRKDMPDADFATWVRPVDLACIILFLASDDARAIHGAGI
HHCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCC
PVRGAS
CCCCCC
>Mature Secondary Structure
MIVTEEKGALPPDLSRARTVIVTGAAGTLGRAVAKAFGGVGANLVLIDREESALRSAFDN
CEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHC
AGENMLLCAARLDEPAAAIPVVEQAVERFGAIDVLCNVAGGFYAGDCVHEMRDETWDLLT
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHC
NTNARTVLHMAQAVIPKMIAARYGKVINVAAMAAQAGMAHMGAYCASKSAVLRLTEAMSA
CCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ELRGHGINVNSVMPSIIDTAQNRKDMPDADFATWVRPVDLACIILFLASDDARAIHGAGI
HHCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCC
PVRGAS
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]