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The map label for this gene is 91782234

Identifier: 91782234

GI number: 91782234

Start: 953953

End: 955146

Strand: Direct

Name: 91782234

Synonym: Bxe_A3601

Alternate gene names: NA

Gene position: 953953-955146 (Clockwise)

Preceding gene: 91782233

Following gene: 91782235

Centisome position: 19.48

GC content: 62.81

Gene sequence:

>1194_bases
GTGAACGGCAACGTGGCTGTCATGGGGGCGAGCGCGATCCCGATCGGGCGACACCAGTCGGATCCGAACGGGCCGTTACA
GACGCTCGAACACGAGATCCTCGCGAAGCTGGTGGTTCAGGCTGCGCGCGATGCACACATCGAGAAGGATGACATCGGCG
GTCTCGTGTTCACCTCGCCGAGGACCTACACGCGGCAAAAATATCTGCATACATTCATGGCCAATTACTTGCGGTTGCCG
TGCGACGGCACCGTCATGGAAGTGATGGGGAACGGCATGACGGCCGCGCTCGCGTTCGACGAAGCGGCGAACCAGATCAG
GCTCGGGCGGGCGAAAGTCGTGCTGGCGCTCGGGATCAACATGGAGTCGGCGATCTCGTCTACCGAGCATGCAATGAGCA
GCATGCGTGCGACGGGCGACATCGATTTTCACGCCACCGCCGGATTCATTCCTATCTCCTGGTATGCGATGGATGCCACG
CGGTACATGTATCAATACGGCGCGACGCGTGAGCAGATTGCGTCTGTGGCCGTCAAGAACCGGTATCACGCTTCGCTCAA
TCCGCTCGCGCAATACCGTAAGCCCATTTCTCTCGAAGACGTGCTCGCGCAGCGTCCGATCGTTGAGCCGCTCGGGCTCT
ACGAAGTTCCTCCACGGGGGGACGGCGCGGCCTGCATCGTACTAGCTTCGGAAGAGGTGGCGAGGAGCACGGGTCGGCCC
TACGCGCTGCTGCGCGGCCGCGGCTTCCATCACGAGGGGGCGCATCAGATCAGCGAGGTGCCGAACGACATGATCGAGTT
CAACGCGGCCGTGCGAGCCGGCGCTGCAGCCTATCGCGAGGCGGGCATCGAGGCGCGCGATATCGACATCGCCGAGGTCT
ACGCGCCGTGCACGATCGTCGAGGTGATCGTGAGCGAAGCGCTCGGTTTCTTCGCTCGCGGCGAAGGCGCGGCGGCCGCG
GCGGCGAAAGAAACGACGCTTGGCGGTCGTATTCCGATTTCGACCTCGGGCGGTCTCACATCGCGCGGACATCCCGCTCT
GGTGACCTCACTCTATAACGTTGTCGAACTGGTCGATCAGTTGCTGAACCGTGCAGGCGAACGGCAAGTCACAGACGCCC
GCTGGGGACTGACAACTGGCGAACTCGGCAACTACAACGCGGCGCTCGTTCACGTGCTGGAGGCGATCCGATGA

Upstream 100 bases:

>100_bases
CCGGTTCCGCCGCGCTATCAGGCGACGCAGGCGCAAACCGGTCTCACGCAATGACGCCGGCGACAACGCCGAAATATTCA
TCCGGAACAGGAGTCGATTT

Downstream 100 bases:

>100_bases
ACCTCACTACCATTTTGATGCCGCGCGAGCGGGCATATCCGCCGCGTGTCTCGGCATTTACGGAGCCGTACTGGAAGGCT
CTGTCGGACGGTCGTCTGAT

Product: hypothetical protein

Products: CoA; 3-oxoacyl-CoA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MNGNVAVMGASAIPIGRHQSDPNGPLQTLEHEILAKLVVQAARDAHIEKDDIGGLVFTSPRTYTRQKYLHTFMANYLRLP
CDGTVMEVMGNGMTAALAFDEAANQIRLGRAKVVLALGINMESAISSTEHAMSSMRATGDIDFHATAGFIPISWYAMDAT
RYMYQYGATREQIASVAVKNRYHASLNPLAQYRKPISLEDVLAQRPIVEPLGLYEVPPRGDGAACIVLASEEVARSTGRP
YALLRGRGFHHEGAHQISEVPNDMIEFNAAVRAGAAAYREAGIEARDIDIAEVYAPCTIVEVIVSEALGFFARGEGAAAA
AAKETTLGGRIPISTSGGLTSRGHPALVTSLYNVVELVDQLLNRAGERQVTDARWGLTTGELGNYNAALVHVLEAIR

Sequences:

>Translated_397_residues
MNGNVAVMGASAIPIGRHQSDPNGPLQTLEHEILAKLVVQAARDAHIEKDDIGGLVFTSPRTYTRQKYLHTFMANYLRLP
CDGTVMEVMGNGMTAALAFDEAANQIRLGRAKVVLALGINMESAISSTEHAMSSMRATGDIDFHATAGFIPISWYAMDAT
RYMYQYGATREQIASVAVKNRYHASLNPLAQYRKPISLEDVLAQRPIVEPLGLYEVPPRGDGAACIVLASEEVARSTGRP
YALLRGRGFHHEGAHQISEVPNDMIEFNAAVRAGAAAYREAGIEARDIDIAEVYAPCTIVEVIVSEALGFFARGEGAAAA
AAKETTLGGRIPISTSGGLTSRGHPALVTSLYNVVELVDQLLNRAGERQVTDARWGLTTGELGNYNAALVHVLEAIR
>Mature_397_residues
MNGNVAVMGASAIPIGRHQSDPNGPLQTLEHEILAKLVVQAARDAHIEKDDIGGLVFTSPRTYTRQKYLHTFMANYLRLP
CDGTVMEVMGNGMTAALAFDEAANQIRLGRAKVVLALGINMESAISSTEHAMSSMRATGDIDFHATAGFIPISWYAMDAT
RYMYQYGATREQIASVAVKNRYHASLNPLAQYRKPISLEDVLAQRPIVEPLGLYEVPPRGDGAACIVLASEEVARSTGRP
YALLRGRGFHHEGAHQISEVPNDMIEFNAAVRAGAAAYREAGIEARDIDIAEVYAPCTIVEVIVSEALGFFARGEGAAAA
AAKETTLGGRIPISTSGGLTSRGHPALVTSLYNVVELVDQLLNRAGERQVTDARWGLTTGELGNYNAALVHVLEAIR

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI302344767, Length=307, Percent_Identity=28.0130293159609, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI302344760, Length=307, Percent_Identity=28.0130293159609, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI19923233, Length=307, Percent_Identity=28.0130293159609, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI302344762, Length=294, Percent_Identity=28.2312925170068, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI55956775, Length=262, Percent_Identity=26.7175572519084, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17537653, Length=224, Percent_Identity=31.6964285714286, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24585051, Length=312, Percent_Identity=28.2051282051282, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI19921506, Length=312, Percent_Identity=27.5641025641026, Blast_Score=98, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: 2.3.1.16

Molecular weight: Translated: 42714; Mature: 42714

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGNVAVMGASAIPIGRHQSDPNGPLQTLEHEILAKLVVQAARDAHIEKDDIGGLVFTSP
CCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCCEEEEECC
RTYTRQKYLHTFMANYLRLPCDGTVMEVMGNGMTAALAFDEAANQIRLGRAKVVLALGIN
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEEHHHHHHHEECCCEEEEEEECCC
MESAISSTEHAMSSMRATGDIDFHATAGFIPISWYAMDATRYMYQYGATREQIASVAVKN
HHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEEEHHHHHHHHHHCCCHHHHHHHHHHC
RYHASLNPLAQYRKPISLEDVLAQRPIVEPLGLYEVPPRGDGAACIVLASEEVARSTGRP
CCCCCCCHHHHHCCCCCHHHHHHHCCCCCCCCCEECCCCCCCCEEEEEECHHHHHHCCCC
YALLRGRGFHHEGAHQISEVPNDMIEFNAAVRAGAAAYREAGIEARDIDIAEVYAPCTIV
EEEEECCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
EVIVSEALGFFARGEGAAAAAAKETTLGGRIPISTSGGLTSRGHPALVTSLYNVVELVDQ
HHHHHHHHHHHCCCCCCHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
LLNRAGERQVTDARWGLTTGELGNYNAALVHVLEAIR
HHHHCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHC
>Mature Secondary Structure
MNGNVAVMGASAIPIGRHQSDPNGPLQTLEHEILAKLVVQAARDAHIEKDDIGGLVFTSP
CCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCCEEEEECC
RTYTRQKYLHTFMANYLRLPCDGTVMEVMGNGMTAALAFDEAANQIRLGRAKVVLALGIN
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEEHHHHHHHEECCCEEEEEEECCC
MESAISSTEHAMSSMRATGDIDFHATAGFIPISWYAMDATRYMYQYGATREQIASVAVKN
HHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEEEHHHHHHHHHHCCCHHHHHHHHHHC
RYHASLNPLAQYRKPISLEDVLAQRPIVEPLGLYEVPPRGDGAACIVLASEEVARSTGRP
CCCCCCCHHHHHCCCCCHHHHHHHCCCCCCCCCEECCCCCCCCEEEEEECHHHHHHCCCC
YALLRGRGFHHEGAHQISEVPNDMIEFNAAVRAGAAAYREAGIEARDIDIAEVYAPCTIV
EEEEECCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
EVIVSEALGFFARGEGAAAAAAKETTLGGRIPISTSGGLTSRGHPALVTSLYNVVELVDQ
HHHHHHHHHHHCCCCCCHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
LLNRAGERQVTDARWGLTTGELGNYNAALVHVLEAIR
HHHHCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acetyl-CoA

Specific reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]