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The map label for this gene is xdhA [H]

Identifier: 91781959

GI number: 91781959

Start: 645525

End: 647891

Strand: Direct

Name: xdhA [H]

Synonym: Bxe_A3885

Alternate gene names: 91781959

Gene position: 645525-647891 (Clockwise)

Preceding gene: 91781958

Following gene: 91781960

Centisome position: 13.19

GC content: 64.81

Gene sequence:

>2367_bases
ATGAATCAGCAAGCCGAACCGTTCCTGAAAAACCTTCAGGATCCCGACGACTTCACCCAGGTCCACATCTCGCGTCCGCA
CGAGTCCGCGCATCTGCACGTGAGCGGCCGCGCCACCTACACCGACGATATTCCGACGCTCGCCGGCACGCTGCACGCGG
CGCTCGGCCTTTCGTCGAAAGCGCATGCGAAGATCGTCTCGATCTCGCTCGACAAGGTGCGCGCCACGCCGGGCGTGGTC
GCGATCTTCACCGCCGACGATATCCCGGGCGTCAACGACGTCGGCCCGATCATCCACGGCGACGATCCGATTCTCGCCGA
CGGCCTCGTGCAATACATCGGGCAGCCGATCTTCATCGTGGTCGCGACGTCGCATGAAACCGCGCGTCTGGCTGCGCGCC
GCGCGGAAATCGTCTACGAGGAACTGCCCGCGATTCTCACCGCGCAGCAGGCCCGCGCCGCGAACCAGCACGTGCTGCCG
CCGATGAAACTCGCGCGCGGAGAAGCCGGCACGAAGATCGCCCGCGCCGCGCATCGCGAAGCCGGCGAGATGCTGCTCGG
CGGCCAGGAGCAGTTCTACCTGGAAGGCCAGATTTCGTACGCGGTGCCGAAAGACGACGACGGCATGCACGTCTACTGCT
CGACGCAGCATCCGACCGAGATGCAGCACCTGGTCGCGCATGCGTTGGGCGTGGCGTCGCACAACGTGCTGATCGAATGC
CGCCGTATGGGCGGCGGCTTCGGCGGCAAGGAATCGCAATCGGGTCTGTTCGCGTGCTGCGCGGCGCTCGCCGCATGGAA
GCTGCTGTGCCCGGTGAAACTGCGTCCGGACCGTGACGACGACATGATGGTCACGGGCAAGCGCCACGATTTCCACTACA
CGTATGAAGTCGGCTACGACGACAAGGGCGTGATCGACGGCGTGACGGTCGACATGACCTCGCGCTGCGGCTTTTCCGCC
GACCTGTCCGGTCCGGTGATGACACGCGCGCTGTGCCACTTCGACAACGCGTACTGGCTCCCGGATGTCACGATCGACGG
CTTCTGCGGCAAGACCAATACGCAGTCGAACACGGCGTTCCGCGGCTTCGGCGGTCCGCAAGGCGCGTTCGCGATCGAAT
ACATCATGGACAACGTGGCGCGCTCGGTGGGCGAGGATTCGCTCGACGTGCGCCGCCGCAATCTGTACGGCAAGACCGAG
CGCAACCAGACGCCGTACGGCCAGATCGTCGAAGACAACGTGATCCACGAGTTGATCGACGAACTCGAAGCGACCAGCGA
ATACCGCGCGCGGCGCGCGGCGATCAACGAGTTCAACGCGAACAACGCAATCCTGAAGAAGGGCATGGCGCTGACGCCGG
TCAAGTTCGGTATCGCGTTCAACGTGACCCACTTCAATCAGGCCGGCGCGCTGGTGCATATCTACACCGACGGTTCGGTG
CTGGTGAACCACGGCGGCACCGAAATGGGCCAGGGTTTGAACACCAAGGTCGCGCAGGTCGTCGCGCATGAACTGGGCAT
TGGCTTTAACCGCATTCGCGTGACGGCAACCGACACCAGCAAGATCGCCAATACGTCGGCGACGGCGGCCTCGACGGGCT
CCGATCTGAACGGCAAGGCCGCGCAGGACGCTGCGCGCCAGTTGCGCGAACGTCTGTCCGCGTTTGCCGCTGAGCGCTTC
GGCGCGGGACAGGTGAGCGCGTCGGAAGTGCGCTTCGCGCATGACCGGGTGGTGGTGGGCGATTCAGTCGTGCCGTTCGA
GGAAGTGATCGCGAAGGCTTATCTGGCGCGTATCCAGCTCTGGTCGGACGGCTTCTATGCGACGCCCAAGCTCTACTGGG
ATCAATCGAAGCTGCAAGGCCGGCCGTTCTACTACTACTCGTACGGCGCGGCCGTGTCGGAAGTGGTGATCGACACGTTG
ACCGGCGAAATGCGCGTGCTTCGTGCGGACGCGTTGCACGACGTGGGCGCCTCGTTGAACCCGGCACTCGACGTCGGCCA
GGTGGAAGGCGCCTTCATTCAGGGCATGGGCTGGCTCACGACCGAAGAACTGTGGTGGAACGCGGGCGGCAAGCTGATGA
CGCACGCGCCGTCCACCTACAAGATTCCGACCGTCAACGATACGCCGCCGGACTTCCGCGTGCGCCTCTTCAAGAACCGC
AACGCCGAGGACAGCATCCATCGTTCGAAGGCGACCGGCGAGCCGCCGCTGCTGCTGCCGTTCTCGGTGTTCTTCGCCGT
GCGCGATGCGGTGTCGGCAGTCGGCGGCCATAAGGTTAATCCGCCGCTGAACGCACCCGCGACCAGCGAGGAAATCCTCA
AGGCGGTCGGCGCGGTGCGGGCTGCCACCGCGGCGCCGCGCCGTTAA

Upstream 100 bases:

>100_bases
ACAATCCGCTGCCGAAGAGCGCGCTGGACGTGCGCGCGGTCGCCGCGGCCTGCGCGCCGGCCGGCGTCTGAAAAGCCCAA
AGGATACGGAGAACACAACA

Downstream 100 bases:

>100_bases
GTGTGGCCGAAGCGCAGTAACGAACGAGCCGGGAAACCAGCGCATGGACAACACGCTCACTGGAATTGGAACGATCGCCA
TGAACGATTTTTCGTCCGTT

Product: xanthine dehydrogenase, molybdenum binding subunit apoprotein / xanthine oxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 788; Mature: 788

Protein sequence:

>788_residues
MNQQAEPFLKNLQDPDDFTQVHISRPHESAHLHVSGRATYTDDIPTLAGTLHAALGLSSKAHAKIVSISLDKVRATPGVV
AIFTADDIPGVNDVGPIIHGDDPILADGLVQYIGQPIFIVVATSHETARLAARRAEIVYEELPAILTAQQARAANQHVLP
PMKLARGEAGTKIARAAHREAGEMLLGGQEQFYLEGQISYAVPKDDDGMHVYCSTQHPTEMQHLVAHALGVASHNVLIEC
RRMGGGFGGKESQSGLFACCAALAAWKLLCPVKLRPDRDDDMMVTGKRHDFHYTYEVGYDDKGVIDGVTVDMTSRCGFSA
DLSGPVMTRALCHFDNAYWLPDVTIDGFCGKTNTQSNTAFRGFGGPQGAFAIEYIMDNVARSVGEDSLDVRRRNLYGKTE
RNQTPYGQIVEDNVIHELIDELEATSEYRARRAAINEFNANNAILKKGMALTPVKFGIAFNVTHFNQAGALVHIYTDGSV
LVNHGGTEMGQGLNTKVAQVVAHELGIGFNRIRVTATDTSKIANTSATAASTGSDLNGKAAQDAARQLRERLSAFAAERF
GAGQVSASEVRFAHDRVVVGDSVVPFEEVIAKAYLARIQLWSDGFYATPKLYWDQSKLQGRPFYYYSYGAAVSEVVIDTL
TGEMRVLRADALHDVGASLNPALDVGQVEGAFIQGMGWLTTEELWWNAGGKLMTHAPSTYKIPTVNDTPPDFRVRLFKNR
NAEDSIHRSKATGEPPLLLPFSVFFAVRDAVSAVGGHKVNPPLNAPATSEEILKAVGAVRAATAAPRR

Sequences:

>Translated_788_residues
MNQQAEPFLKNLQDPDDFTQVHISRPHESAHLHVSGRATYTDDIPTLAGTLHAALGLSSKAHAKIVSISLDKVRATPGVV
AIFTADDIPGVNDVGPIIHGDDPILADGLVQYIGQPIFIVVATSHETARLAARRAEIVYEELPAILTAQQARAANQHVLP
PMKLARGEAGTKIARAAHREAGEMLLGGQEQFYLEGQISYAVPKDDDGMHVYCSTQHPTEMQHLVAHALGVASHNVLIEC
RRMGGGFGGKESQSGLFACCAALAAWKLLCPVKLRPDRDDDMMVTGKRHDFHYTYEVGYDDKGVIDGVTVDMTSRCGFSA
DLSGPVMTRALCHFDNAYWLPDVTIDGFCGKTNTQSNTAFRGFGGPQGAFAIEYIMDNVARSVGEDSLDVRRRNLYGKTE
RNQTPYGQIVEDNVIHELIDELEATSEYRARRAAINEFNANNAILKKGMALTPVKFGIAFNVTHFNQAGALVHIYTDGSV
LVNHGGTEMGQGLNTKVAQVVAHELGIGFNRIRVTATDTSKIANTSATAASTGSDLNGKAAQDAARQLRERLSAFAAERF
GAGQVSASEVRFAHDRVVVGDSVVPFEEVIAKAYLARIQLWSDGFYATPKLYWDQSKLQGRPFYYYSYGAAVSEVVIDTL
TGEMRVLRADALHDVGASLNPALDVGQVEGAFIQGMGWLTTEELWWNAGGKLMTHAPSTYKIPTVNDTPPDFRVRLFKNR
NAEDSIHRSKATGEPPLLLPFSVFFAVRDAVSAVGGHKVNPPLNAPATSEEILKAVGAVRAATAAPRR
>Mature_788_residues
MNQQAEPFLKNLQDPDDFTQVHISRPHESAHLHVSGRATYTDDIPTLAGTLHAALGLSSKAHAKIVSISLDKVRATPGVV
AIFTADDIPGVNDVGPIIHGDDPILADGLVQYIGQPIFIVVATSHETARLAARRAEIVYEELPAILTAQQARAANQHVLP
PMKLARGEAGTKIARAAHREAGEMLLGGQEQFYLEGQISYAVPKDDDGMHVYCSTQHPTEMQHLVAHALGVASHNVLIEC
RRMGGGFGGKESQSGLFACCAALAAWKLLCPVKLRPDRDDDMMVTGKRHDFHYTYEVGYDDKGVIDGVTVDMTSRCGFSA
DLSGPVMTRALCHFDNAYWLPDVTIDGFCGKTNTQSNTAFRGFGGPQGAFAIEYIMDNVARSVGEDSLDVRRRNLYGKTE
RNQTPYGQIVEDNVIHELIDELEATSEYRARRAAINEFNANNAILKKGMALTPVKFGIAFNVTHFNQAGALVHIYTDGSV
LVNHGGTEMGQGLNTKVAQVVAHELGIGFNRIRVTATDTSKIANTSATAASTGSDLNGKAAQDAARQLRERLSAFAAERF
GAGQVSASEVRFAHDRVVVGDSVVPFEEVIAKAYLARIQLWSDGFYATPKLYWDQSKLQGRPFYYYSYGAAVSEVVIDTL
TGEMRVLRADALHDVGASLNPALDVGQVEGAFIQGMGWLTTEELWWNAGGKLMTHAPSTYKIPTVNDTPPDFRVRLFKNR
NAEDSIHRSKATGEPPLLLPFSVFFAVRDAVSAVGGHKVNPPLNAPATSEEILKAVGAVRAATAAPRR

Specific function: Presumed to be a dehydrogenase, but possibly an oxidase. Participates in limited purine salvage (requires aspartate) but does not support aerobic growth on purines as the sole carbon source (purine catabolism) [H]

COG id: COG4631

COG function: function code F; Xanthine dehydrogenase, molybdopterin-binding subunit B

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=758, Percent_Identity=42.8759894459103, Blast_Score=593, Evalue=1e-169,
Organism=Homo sapiens, GI71773480, Length=771, Percent_Identity=38.0025940337224, Blast_Score=473, Evalue=1e-133,
Organism=Escherichia coli, GI1789230, Length=766, Percent_Identity=28.7206266318538, Blast_Score=209, Evalue=5e-55,
Organism=Escherichia coli, GI1789246, Length=774, Percent_Identity=25.8397932816537, Blast_Score=187, Evalue=3e-48,
Organism=Escherichia coli, GI1786478, Length=779, Percent_Identity=23.7483953786906, Blast_Score=84, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17540638, Length=766, Percent_Identity=39.9477806788512, Blast_Score=496, Evalue=1e-140,
Organism=Caenorhabditis elegans, GI32566215, Length=709, Percent_Identity=31.4527503526093, Blast_Score=337, Evalue=1e-92,
Organism=Caenorhabditis elegans, GI17539860, Length=723, Percent_Identity=32.5034578146611, Blast_Score=327, Evalue=2e-89,
Organism=Drosophila melanogaster, GI17737937, Length=760, Percent_Identity=42.2368421052632, Blast_Score=571, Evalue=1e-163,
Organism=Drosophila melanogaster, GI24647193, Length=770, Percent_Identity=32.4675324675325, Blast_Score=330, Evalue=3e-90,
Organism=Drosophila melanogaster, GI24647199, Length=770, Percent_Identity=31.9480519480519, Blast_Score=328, Evalue=8e-90,
Organism=Drosophila melanogaster, GI24647195, Length=774, Percent_Identity=30.6201550387597, Blast_Score=300, Evalue=3e-81,
Organism=Drosophila melanogaster, GI24647197, Length=774, Percent_Identity=30.6201550387597, Blast_Score=299, Evalue=5e-81,
Organism=Drosophila melanogaster, GI24647201, Length=764, Percent_Identity=31.282722513089, Blast_Score=297, Evalue=2e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 85415; Mature: 85415

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQQAEPFLKNLQDPDDFTQVHISRPHESAHLHVSGRATYTDDIPTLAGTLHAALGLSSK
CCCCCCHHHHCCCCCCCCEEEEEECCCCCEEEEEECCEEECCCCHHHHHHHHHHHCCCCC
AHAKIVSISLDKVRATPGVVAIFTADDIPGVNDVGPIIHGDDPILADGLVQYIGQPIFIV
CCEEEEEEEHHHHCCCCCEEEEEECCCCCCCCCCCCEEECCCCHHHHHHHHHCCCCEEEE
VATSHETARLAARRAEIVYEELPAILTAQQARAANQHVLPPMKLARGEAGTKIARAAHRE
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCHHHHHHHHHH
AGEMLLGGQEQFYLEGQISYAVPKDDDGMHVYCSTQHPTEMQHLVAHALGVASHNVLIEC
HCHHHCCCCCEEEEEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEE
RRMGGGFGGKESQSGLFACCAALAAWKLLCPVKLRPDRDDDMMVTGKRHDFHYTYEVGYD
EECCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEECCCCCCCEEEECCCCCEEEEEEECCC
DKGVIDGVTVDMTSRCGFSADLSGPVMTRALCHFDNAYWLPDVTIDGFCGKTNTQSNTAF
CCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCEECCCCEECCCCCCCCCCCCCEE
RGFGGPQGAFAIEYIMDNVARSVGEDSLDVRRRNLYGKTERNQTPYGQIVEDNVIHELID
ECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
ELEATSEYRARRAAINEFNANNAILKKGMALTPVKFGIAFNVTHFNQAGALVHIYTDGSV
HHHHHHHHHHHHHHHHHCCCCCHHHHCCCEECEEEEEEEEEEEEECCCCCEEEEEECCEE
LVNHGGTEMGQGLNTKVAQVVAHELGIGFNRIRVTATDTSKIANTSATAASTGSDLNGKA
EEECCCHHHCCCCCHHHHHHHHHHHCCCEEEEEEEECCCHHHCCCCCCCCCCCCCCCCHH
AQDAARQLRERLSAFAAERFGAGQVSASEVRFAHDRVVVGDSVVPFEEVIAKAYLARIQL
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEECCEEEECCCCCCHHHHHHHHHHHHHEE
WSDGFYATPKLYWDQSKLQGRPFYYYSYGAAVSEVVIDTLTGEMRVLRADALHDVGASLN
ECCCCEECCEEEECHHHCCCCCEEEEECCHHHHHHHHHHHCCCCEEHHHHHHHHCCCCCC
PALDVGQVEGAFIQGMGWLTTEELWWNAGGKLMTHAPSTYKIPTVNDTPPDFRVRLFKNR
CCCCCCCCCCHHEECCCCCCHHHHHHCCCCCEEEECCCCEECCCCCCCCCCCEEEEEECC
NAEDSIHRSKATGEPPLLLPFSVFFAVRDAVSAVGGHKVNPPLNAPATSEEILKAVGAVR
CCHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
AATAAPRR
HHHCCCCC
>Mature Secondary Structure
MNQQAEPFLKNLQDPDDFTQVHISRPHESAHLHVSGRATYTDDIPTLAGTLHAALGLSSK
CCCCCCHHHHCCCCCCCCEEEEEECCCCCEEEEEECCEEECCCCHHHHHHHHHHHCCCCC
AHAKIVSISLDKVRATPGVVAIFTADDIPGVNDVGPIIHGDDPILADGLVQYIGQPIFIV
CCEEEEEEEHHHHCCCCCEEEEEECCCCCCCCCCCCEEECCCCHHHHHHHHHCCCCEEEE
VATSHETARLAARRAEIVYEELPAILTAQQARAANQHVLPPMKLARGEAGTKIARAAHRE
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCHHHHHHHHHH
AGEMLLGGQEQFYLEGQISYAVPKDDDGMHVYCSTQHPTEMQHLVAHALGVASHNVLIEC
HCHHHCCCCCEEEEEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEE
RRMGGGFGGKESQSGLFACCAALAAWKLLCPVKLRPDRDDDMMVTGKRHDFHYTYEVGYD
EECCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEECCCCCCCEEEECCCCCEEEEEEECCC
DKGVIDGVTVDMTSRCGFSADLSGPVMTRALCHFDNAYWLPDVTIDGFCGKTNTQSNTAF
CCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCEECCCCEECCCCCCCCCCCCCEE
RGFGGPQGAFAIEYIMDNVARSVGEDSLDVRRRNLYGKTERNQTPYGQIVEDNVIHELID
ECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
ELEATSEYRARRAAINEFNANNAILKKGMALTPVKFGIAFNVTHFNQAGALVHIYTDGSV
HHHHHHHHHHHHHHHHHCCCCCHHHHCCCEECEEEEEEEEEEEEECCCCCEEEEEECCEE
LVNHGGTEMGQGLNTKVAQVVAHELGIGFNRIRVTATDTSKIANTSATAASTGSDLNGKA
EEECCCHHHCCCCCHHHHHHHHHHHCCCEEEEEEEECCCHHHCCCCCCCCCCCCCCCCHH
AQDAARQLRERLSAFAAERFGAGQVSASEVRFAHDRVVVGDSVVPFEEVIAKAYLARIQL
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEECCEEEECCCCCCHHHHHHHHHHHHHEE
WSDGFYATPKLYWDQSKLQGRPFYYYSYGAAVSEVVIDTLTGEMRVLRADALHDVGASLN
ECCCCEECCEEEECHHHCCCCCEEEEECCHHHHHHHHHHHCCCCEEHHHHHHHHCCCCCC
PALDVGQVEGAFIQGMGWLTTEELWWNAGGKLMTHAPSTYKIPTVNDTPPDFRVRLFKNR
CCCCCCCCCCHHEECCCCCCHHHHHHCCCCCEEEECCCCEECCCCCCCCCCCEEEEEECC
NAEDSIHRSKATGEPPLLLPFSVFFAVRDAVSAVGGHKVNPPLNAPATSEEILKAVGAVR
CCHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
AATAAPRR
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]