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The map label for this gene is hcrC [H]

Identifier: 91781958

GI number: 91781958

Start: 643972

End: 645495

Strand: Direct

Name: hcrC [H]

Synonym: Bxe_A3886

Alternate gene names: 91781958

Gene position: 643972-645495 (Clockwise)

Preceding gene: 91781957

Following gene: 91781959

Centisome position: 13.15

GC content: 65.03

Gene sequence:

>1524_bases
ATGACTGAGCCGATTCGCTTCTATCACCGCAACGCGATCCGCGAGATCAAGGACGCGCCCGTCACCCGCACGGTCCTGCA
ATATCTGCGCGAAGACGCGCATTGCACGGGCACCAAGGAAGGCTGCGCCGAAGGCGACTGCGGCGCATGCACGGTCGTGA
TCGGCGAGCGCAACGAGGCGGGCGGCGTCGACTTCAAGGCGGTGAATGCCTGCATCCAGTTCGTGCCGACGCTCGACGGC
AAAGCGCTCTTCACCGTCGAAGACCTGCGCCAGCCGGACGGCTCGCTGCATCCGGTACAGGAAGCGATGGTCGAATGTCA
CGGCTCGCAGTGCGGTTTCTGCACGCCGGGCTTCGTCATGTCGATGTGGTCGCTCTACGAAAAGCACGGCCACGAGCACA
GTTGCGCCAACAGGACGGTGCCGTCGCGTGAAGCGATCAGCAACGCGTTGACGGGCAATCTGTGCCGCTGCACGGGCTAC
CGTCCGATCGTCGACGCGGCGGTACGCATGTTCGAAGCGCCCGCGCCGAAAGCGCCGGTGAACGTCGAAGCGCTCGTCCG
CGCGCTCGGCACGCTCGAACGCACGGACACATTCCACTATGAGCACGCGGGCCAGCAGTTCGACGCGCCGCGCACGGTCG
AGGCGCTCGCCAGGATCAAGGAAGCCGAACCGGCCACGCGCATTCTTGCCGGCAGCACGGACATTGGCCTGTGGGTCACC
AAGCAGATGCGCGAGCTCGGCAACATCGTCTATGTGGGGCAGATCGCCGGGTTGCAGAAGCTCGAAACCAATGGCGAATG
GATCGAGATCGGCGCGGGTGTCAGCGTCGAAAAGGCTTATGCGGAGATCGCGAAGCAATATCCCGAACTGAACGAAATGT
GGCAACGCTTCGCGTCCCTGCCGATTCGCAATGCCGGCACGCTCGGCGGCAACATCGCCAACGGCTCGCCGATCGGCGAT
TCGATGCCGGGTCTGATTGCACTCGGCGCGCGCGTGATCGTGCGCGGCGGCGAGATCGAGCGCGAAATGCCGCTCGAAGA
TCTGTACCTCGCGTATCAGAAGAAGGACATGGCGGAGCACGAGTTCGTCGTCGGGCTGAAAGTGCCGACGCGCAGCGGCG
TGCGTCAGAACCTGCAATTCCGCACCTACAAACTTTCGAAGCGTTTCGATTCGGACATCTCGGCGGTGTGCGCCGCTTTC
GCTTTTATCGCCGACGGCAACCTGATCCGCGAGCCGCGCATCGCATTCGGCGGCATGGCCGCTACGTCCAAACGGGCGAC
GCACGCGGAAGCCGTGCTGCGCGACGCCGAATGGCACGAAGCGACGGCGCAGGCGGCGATGCTCGCGCTCGGCAACGACT
ACGCGCCGTTGTCCGACATGCGCGCGACCAGCAACTATCGCCTCGAATCGGCGAAGAACACGCTGTACCGCTTCTGGCTC
GAAACGCGGCCGGACAATCCGCTGCCGAAGAGCGCGCTGGACGTGCGCGCGGTCGCCGCGGCCTGCGCGCCGGCCGGCGT
CTGA

Upstream 100 bases:

>100_bases
TGCGATCGGAGCTATGGGTTGTGTTTATTGACGGTGATAGTTTTCAAACCATCCCTGCTGCACGTCCCCGCGGACACAGA
ACATTCGAGAGTAACGAGAC

Downstream 100 bases:

>100_bases
AAAGCCCAAAGGATACGGAGAACACAACAATGAATCAGCAAGCCGAACCGTTCCTGAAAAACCTTCAGGATCCCGACGAC
TTCACCCAGGTCCACATCTC

Product: putative xanthine dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 507; Mature: 506

Protein sequence:

>507_residues
MTEPIRFYHRNAIREIKDAPVTRTVLQYLREDAHCTGTKEGCAEGDCGACTVVIGERNEAGGVDFKAVNACIQFVPTLDG
KALFTVEDLRQPDGSLHPVQEAMVECHGSQCGFCTPGFVMSMWSLYEKHGHEHSCANRTVPSREAISNALTGNLCRCTGY
RPIVDAAVRMFEAPAPKAPVNVEALVRALGTLERTDTFHYEHAGQQFDAPRTVEALARIKEAEPATRILAGSTDIGLWVT
KQMRELGNIVYVGQIAGLQKLETNGEWIEIGAGVSVEKAYAEIAKQYPELNEMWQRFASLPIRNAGTLGGNIANGSPIGD
SMPGLIALGARVIVRGGEIEREMPLEDLYLAYQKKDMAEHEFVVGLKVPTRSGVRQNLQFRTYKLSKRFDSDISAVCAAF
AFIADGNLIREPRIAFGGMAATSKRATHAEAVLRDAEWHEATAQAAMLALGNDYAPLSDMRATSNYRLESAKNTLYRFWL
ETRPDNPLPKSALDVRAVAAACAPAGV

Sequences:

>Translated_507_residues
MTEPIRFYHRNAIREIKDAPVTRTVLQYLREDAHCTGTKEGCAEGDCGACTVVIGERNEAGGVDFKAVNACIQFVPTLDG
KALFTVEDLRQPDGSLHPVQEAMVECHGSQCGFCTPGFVMSMWSLYEKHGHEHSCANRTVPSREAISNALTGNLCRCTGY
RPIVDAAVRMFEAPAPKAPVNVEALVRALGTLERTDTFHYEHAGQQFDAPRTVEALARIKEAEPATRILAGSTDIGLWVT
KQMRELGNIVYVGQIAGLQKLETNGEWIEIGAGVSVEKAYAEIAKQYPELNEMWQRFASLPIRNAGTLGGNIANGSPIGD
SMPGLIALGARVIVRGGEIEREMPLEDLYLAYQKKDMAEHEFVVGLKVPTRSGVRQNLQFRTYKLSKRFDSDISAVCAAF
AFIADGNLIREPRIAFGGMAATSKRATHAEAVLRDAEWHEATAQAAMLALGNDYAPLSDMRATSNYRLESAKNTLYRFWL
ETRPDNPLPKSALDVRAVAAACAPAGV
>Mature_506_residues
TEPIRFYHRNAIREIKDAPVTRTVLQYLREDAHCTGTKEGCAEGDCGACTVVIGERNEAGGVDFKAVNACIQFVPTLDGK
ALFTVEDLRQPDGSLHPVQEAMVECHGSQCGFCTPGFVMSMWSLYEKHGHEHSCANRTVPSREAISNALTGNLCRCTGYR
PIVDAAVRMFEAPAPKAPVNVEALVRALGTLERTDTFHYEHAGQQFDAPRTVEALARIKEAEPATRILAGSTDIGLWVTK
QMRELGNIVYVGQIAGLQKLETNGEWIEIGAGVSVEKAYAEIAKQYPELNEMWQRFASLPIRNAGTLGGNIANGSPIGDS
MPGLIALGARVIVRGGEIEREMPLEDLYLAYQKKDMAEHEFVVGLKVPTRSGVRQNLQFRTYKLSKRFDSDISAVCAAFA
FIADGNLIREPRIAFGGMAATSKRATHAEAVLRDAEWHEATAQAAMLALGNDYAPLSDMRATSNYRLESAKNTLYRFWLE
TRPDNPLPKSALDVRAVAAACAPAGV

Specific function: Catalyzes reductive dehydroxylation of 4-hydroxybenzoyl- CoA. Reaction is not reversible [H]

COG id: COG4630

COG function: function code F; Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=519, Percent_Identity=27.7456647398844, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI71773480, Length=473, Percent_Identity=25.5813953488372, Blast_Score=138, Evalue=1e-32,
Organism=Escherichia coli, GI1786480, Length=156, Percent_Identity=33.3333333333333, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1789231, Length=252, Percent_Identity=26.984126984127, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789232, Length=143, Percent_Identity=35.6643356643357, Blast_Score=79, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17540638, Length=161, Percent_Identity=45.3416149068323, Blast_Score=132, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI17539860, Length=163, Percent_Identity=40.4907975460123, Blast_Score=118, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI32566215, Length=144, Percent_Identity=41.6666666666667, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI17737937, Length=489, Percent_Identity=31.2883435582822, Blast_Score=203, Evalue=2e-52,
Organism=Drosophila melanogaster, GI24647201, Length=505, Percent_Identity=28.1188118811881, Blast_Score=167, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24647199, Length=501, Percent_Identity=27.3453093812375, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24647197, Length=503, Percent_Identity=27.8330019880716, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24647195, Length=321, Percent_Identity=31.4641744548287, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24647193, Length=501, Percent_Identity=27.5449101796407, Blast_Score=147, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR017606
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.20 [H]

Molecular weight: Translated: 55419; Mature: 55287

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS00197 2FE2S_FER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPIRFYHRNAIREIKDAPVTRTVLQYLREDAHCTGTKEGCAEGDCGACTVVIGERNEA
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCC
GGVDFKAVNACIQFVPTLDGKALFTVEDLRQPDGSLHPVQEAMVECHGSQCGFCTPGFVM
CCCCHHHHHHHHHHHCCCCCCEEEEHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHH
SMWSLYEKHGHEHSCANRTVPSREAISNALTGNLCRCTGYRPIVDAAVRMFEAPAPKAPV
HHHHHHHHCCCCCHHHCCCCCCHHHHHHHHCCCCEEECCCCHHHHHHHHHHCCCCCCCCC
NVEALVRALGTLERTDTFHYEHAGQQFDAPRTVEALARIKEAEPATRILAGSTDIGLWVT
CHHHHHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHCCCHHHEEECCCCCHHHHH
KQMRELGNIVYVGQIAGLQKLETNGEWIEIGAGVSVEKAYAEIAKQYPELNEMWQRFASL
HHHHHHCCEEEEEECCCCHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHCC
PIRNAGTLGGNIANGSPIGDSMPGLIALGARVIVRGGEIEREMPLEDLYLAYQKKDMAEH
CCCCCCCCCCCCCCCCCCCCCCCHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCC
EFVVGLKVPTRSGVRQNLQFRTYKLSKRFDSDISAVCAAFAFIADGNLIREPRIAFGGMA
EEEEEEECCCCHHHHHCCHHHEEEHHHHHCCHHHHHHHHHHHHHCCCEECCCCHHHCCCC
ATSKRATHAEAVLRDAEWHEATAQAAMLALGNDYAPLSDMRATSNYRLESAKNTLYRFWL
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCHHHHHHHHEEEHH
ETRPDNPLPKSALDVRAVAAACAPAGV
HCCCCCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TEPIRFYHRNAIREIKDAPVTRTVLQYLREDAHCTGTKEGCAEGDCGACTVVIGERNEA
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCC
GGVDFKAVNACIQFVPTLDGKALFTVEDLRQPDGSLHPVQEAMVECHGSQCGFCTPGFVM
CCCCHHHHHHHHHHHCCCCCCEEEEHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHH
SMWSLYEKHGHEHSCANRTVPSREAISNALTGNLCRCTGYRPIVDAAVRMFEAPAPKAPV
HHHHHHHHCCCCCHHHCCCCCCHHHHHHHHCCCCEEECCCCHHHHHHHHHHCCCCCCCCC
NVEALVRALGTLERTDTFHYEHAGQQFDAPRTVEALARIKEAEPATRILAGSTDIGLWVT
CHHHHHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHCCCHHHEEECCCCCHHHHH
KQMRELGNIVYVGQIAGLQKLETNGEWIEIGAGVSVEKAYAEIAKQYPELNEMWQRFASL
HHHHHHCCEEEEEECCCCHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHCC
PIRNAGTLGGNIANGSPIGDSMPGLIALGARVIVRGGEIEREMPLEDLYLAYQKKDMAEH
CCCCCCCCCCCCCCCCCCCCCCCHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCC
EFVVGLKVPTRSGVRQNLQFRTYKLSKRFDSDISAVCAAFAFIADGNLIREPRIAFGGMA
EEEEEEECCCCHHHHHCCHHHEEEHHHHHCCHHHHHHHHHHHHHCCCEECCCCHHHCCCC
ATSKRATHAEAVLRDAEWHEATAQAAMLALGNDYAPLSDMRATSNYRLESAKNTLYRFWL
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCHHHHHHHHEEEHH
ETRPDNPLPKSALDVRAVAAACAPAGV
HCCCCCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9490068 [H]