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The map label for this gene is mmgC [H]

Identifier: 91781939

GI number: 91781939

Start: 621191

End: 622381

Strand: Reverse

Name: mmgC [H]

Synonym: Bxe_A3904

Alternate gene names: 91781939

Gene position: 622381-621191 (Counterclockwise)

Preceding gene: 91781941

Following gene: 91781937

Centisome position: 12.71

GC content: 62.97

Gene sequence:

>1191_bases
ATGGCCGAGGCCGCGCAGTTTCACTGGGAAGACCCGTTGCTGCTGGATCAGCAACTCACCGAAGACGAACGCATGGTGCG
CGACGCCGCCGCGGCTTACGCGCAGGACAAGCTCCAGCCGCGCGTGCTCGAAGCATTCCGTCACGAGAAGACCGACATCG
AGATCTTTCGCGAGATGGGCGAGCTCGGGCTGCTCGGCCCGACCATTCCCGAACAATACGGTGGTCCCGGCCTGAACTAC
GTCGCTTACGGCCTGATTGCGCGCGAGGTGGAGCGCGTCGATTCCGGCTACCGGTCGATGATGTCAGTGCAGTCGTCGCT
CGTCATGGTGCCGATCCACGCATTCGGCTCCGAAGCGCAAAAGCAGAAATACCTGCCGAAGCTCGCCACCGGCGAGTGGA
TCGGCTGCTTCGGCCTGACCGAGCCGAACCACGGCTCCGATCCGGGCAGCATGGTCACGCGGGCCAAAAAGGTCGACGGC
GGCTATTCGCTGTCGGGCTCGAAAATGTGGATCACCAACTCGCCGATCGCCGACGTGTTCGTGGTGTGGGCAAAGCTCGA
AGAAAACGGCAAGGACGCGATTCGCGGCTTCATTCTGGAGAAGGGCTGGAGAGGGCTGTCGGCGCCGACCATCCACAGCA
AGGTGGGTTTGCGCGCCTCGATCACCGGTGAGATCGTGCTCGACGAAGTGTTCGTGCCGGAAGAGAACCGTTTCCCGGAA
GTCAGCGGTTTGCGCGGTCCGTTCACCTGTCTGAACTCGGCGCGCTACGGCATTGCCTGGGGCGCGCTCGGCGCGGCCGA
AGCATGCTGGCACACCGCGCGCCAGTACGTGCTGGATCGCAAGCAGTTCGGCCGGCCGCTCGCCGCGAACCAGCTGATCC
AGAAGAAGCTCGCCGACATGCAGACCGAGATCACGCTCGGACTGCAAGGCGTGCTGCGTCTCGGCCGCATGAAGGACGAA
GGCACCGCGGCTGTCGAGATCACCTCGATCATGAAGCGCAATTCATGCGGCAAGGCGCTGGATATTGCGCGGCTTGCACG
CGACATGCTCGGCGGCAACGGCATCTCGGACGAGTTCGGCGTCGCGCGGCATCTGGTGAATCTGGAAGTGGTGAACACCT
ATGAAGGCACGCACGACATTCACGCGCTGATTCTGGGGCGCGCACAAACAGGTATTCAGGCTTTCTTCTGA

Upstream 100 bases:

>100_bases
GGTGGTACACTCGGACGTGTTTGCAAAACATTGTTTCGCATAGCGGAACTTAAGTCAAGCTCACGCACGTTTCGTCAAGC
AAGAAATCAGGAGATAAGTC

Downstream 100 bases:

>100_bases
ACGCTGGGATACGCTGATTCCGCCGGCCGTGGCGGGTTTGCGCAGTACGAAAAAAAGCCAGTCCACTTGCGGACTGGCTT
TTCTGTTTTCCTTCGACGCG

Product: putative glutaryl-CoA dehydrogenase

Products: crotonoyl-CoA; CO2; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MAEAAQFHWEDPLLLDQQLTEDERMVRDAAAAYAQDKLQPRVLEAFRHEKTDIEIFREMGELGLLGPTIPEQYGGPGLNY
VAYGLIAREVERVDSGYRSMMSVQSSLVMVPIHAFGSEAQKQKYLPKLATGEWIGCFGLTEPNHGSDPGSMVTRAKKVDG
GYSLSGSKMWITNSPIADVFVVWAKLEENGKDAIRGFILEKGWRGLSAPTIHSKVGLRASITGEIVLDEVFVPEENRFPE
VSGLRGPFTCLNSARYGIAWGALGAAEACWHTARQYVLDRKQFGRPLAANQLIQKKLADMQTEITLGLQGVLRLGRMKDE
GTAAVEITSIMKRNSCGKALDIARLARDMLGGNGISDEFGVARHLVNLEVVNTYEGTHDIHALILGRAQTGIQAFF

Sequences:

>Translated_396_residues
MAEAAQFHWEDPLLLDQQLTEDERMVRDAAAAYAQDKLQPRVLEAFRHEKTDIEIFREMGELGLLGPTIPEQYGGPGLNY
VAYGLIAREVERVDSGYRSMMSVQSSLVMVPIHAFGSEAQKQKYLPKLATGEWIGCFGLTEPNHGSDPGSMVTRAKKVDG
GYSLSGSKMWITNSPIADVFVVWAKLEENGKDAIRGFILEKGWRGLSAPTIHSKVGLRASITGEIVLDEVFVPEENRFPE
VSGLRGPFTCLNSARYGIAWGALGAAEACWHTARQYVLDRKQFGRPLAANQLIQKKLADMQTEITLGLQGVLRLGRMKDE
GTAAVEITSIMKRNSCGKALDIARLARDMLGGNGISDEFGVARHLVNLEVVNTYEGTHDIHALILGRAQTGIQAFF
>Mature_395_residues
AEAAQFHWEDPLLLDQQLTEDERMVRDAAAAYAQDKLQPRVLEAFRHEKTDIEIFREMGELGLLGPTIPEQYGGPGLNYV
AYGLIAREVERVDSGYRSMMSVQSSLVMVPIHAFGSEAQKQKYLPKLATGEWIGCFGLTEPNHGSDPGSMVTRAKKVDGG
YSLSGSKMWITNSPIADVFVVWAKLEENGKDAIRGFILEKGWRGLSAPTIHSKVGLRASITGEIVLDEVFVPEENRFPEV
SGLRGPFTCLNSARYGIAWGALGAAEACWHTARQYVLDRKQFGRPLAANQLIQKKLADMQTEITLGLQGVLRLGRMKDEG
TAAVEITSIMKRNSCGKALDIARLARDMLGGNGISDEFGVARHLVNLEVVNTYEGTHDIHALILGRAQTGIQAFF

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4503943, Length=392, Percent_Identity=67.8571428571429, Blast_Score=536, Evalue=1e-152,
Organism=Homo sapiens, GI7669494, Length=372, Percent_Identity=66.3978494623656, Blast_Score=497, Evalue=1e-141,
Organism=Homo sapiens, GI226958412, Length=376, Percent_Identity=34.8404255319149, Blast_Score=208, Evalue=6e-54,
Organism=Homo sapiens, GI226958414, Length=344, Percent_Identity=35.1744186046512, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI4557233, Length=371, Percent_Identity=31.5363881401617, Blast_Score=185, Evalue=5e-47,
Organism=Homo sapiens, GI4501859, Length=367, Percent_Identity=29.1553133514986, Blast_Score=172, Evalue=4e-43,
Organism=Homo sapiens, GI76496475, Length=384, Percent_Identity=31.7708333333333, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI4557235, Length=384, Percent_Identity=31.7708333333333, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI7656849, Length=372, Percent_Identity=29.8387096774194, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI187960098, Length=399, Percent_Identity=29.8245614035088, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI4557231, Length=399, Percent_Identity=29.8245614035088, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI21361497, Length=350, Percent_Identity=33.1428571428571, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI4501857, Length=384, Percent_Identity=28.6458333333333, Blast_Score=130, Evalue=3e-30,
Organism=Escherichia coli, GI1786223, Length=337, Percent_Identity=26.4094955489614, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI87081958, Length=340, Percent_Identity=27.3529411764706, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17534353, Length=390, Percent_Identity=63.3333333333333, Blast_Score=502, Evalue=1e-142,
Organism=Caenorhabditis elegans, GI17508101, Length=376, Percent_Identity=33.5106382978723, Blast_Score=188, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI17538396, Length=378, Percent_Identity=31.7460317460317, Blast_Score=177, Evalue=7e-45,
Organism=Caenorhabditis elegans, GI17506239, Length=365, Percent_Identity=31.2328767123288, Blast_Score=176, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI17569725, Length=374, Percent_Identity=31.0160427807487, Blast_Score=172, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI71985184, Length=356, Percent_Identity=32.8651685393258, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI71990804, Length=274, Percent_Identity=35.4014598540146, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17534899, Length=375, Percent_Identity=29.6, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI71985192, Length=283, Percent_Identity=34.2756183745583, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI71982178, Length=273, Percent_Identity=32.2344322344322, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17570075, Length=378, Percent_Identity=28.042328042328, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI32563615, Length=231, Percent_Identity=33.7662337662338, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17533517, Length=381, Percent_Identity=25.4593175853018, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17551932, Length=392, Percent_Identity=24.7448979591837, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17505929, Length=347, Percent_Identity=25.6484149855908, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17531909, Length=233, Percent_Identity=28.755364806867, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19920834, Length=398, Percent_Identity=62.5628140703518, Blast_Score=485, Evalue=1e-137,
Organism=Drosophila melanogaster, GI21356377, Length=369, Percent_Identity=32.520325203252, Blast_Score=203, Evalue=1e-52,
Organism=Drosophila melanogaster, GI24666513, Length=365, Percent_Identity=33.1506849315069, Blast_Score=195, Evalue=4e-50,
Organism=Drosophila melanogaster, GI24646207, Length=372, Percent_Identity=33.3333333333333, Blast_Score=190, Evalue=1e-48,
Organism=Drosophila melanogaster, GI21355753, Length=375, Percent_Identity=32, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI281363737, Length=356, Percent_Identity=32.8651685393258, Blast_Score=166, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24660351, Length=378, Percent_Identity=31.2169312169312, Blast_Score=164, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.7

Molecular weight: Translated: 43564; Mature: 43433

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEAAQFHWEDPLLLDQQLTEDERMVRDAAAAYAQDKLQPRVLEAFRHEKTDIEIFREMG
CCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHH
ELGLLGPTIPEQYGGPGLNYVAYGLIAREVERVDSGYRSMMSVQSSLVMVPIHAFGSEAQ
HCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEHHHHCCHHH
KQKYLPKLATGEWIGCFGLTEPNHGSDPGSMVTRAKKVDGGYSLSGSKMWITNSPIADVF
HHHCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCEEECCCEEEEECCCHHHHH
VVWAKLEENGKDAIRGFILEKGWRGLSAPTIHSKVGLRASITGEIVLDEVFVPEENRFPE
HHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHCCCEEECCCEEEEEEEECCCCCCCCC
VSGLRGPFTCLNSARYGIAWGALGAAEACWHTARQYVLDRKQFGRPLAANQLIQKKLADM
CCCCCCCHHHHCCCCCCEEHHCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
QTEITLGLQGVLRLGRMKDEGTAAVEITSIMKRNSCGKALDIARLARDMLGGNGISDEFG
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHH
VARHLVNLEVVNTYEGTHDIHALILGRAQTGIQAFF
HHHHHHEEEEEECCCCCHHHHHHEEHHHHCCHHHCC
>Mature Secondary Structure 
AEAAQFHWEDPLLLDQQLTEDERMVRDAAAAYAQDKLQPRVLEAFRHEKTDIEIFREMG
CCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHH
ELGLLGPTIPEQYGGPGLNYVAYGLIAREVERVDSGYRSMMSVQSSLVMVPIHAFGSEAQ
HCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEHHHHCCHHH
KQKYLPKLATGEWIGCFGLTEPNHGSDPGSMVTRAKKVDGGYSLSGSKMWITNSPIADVF
HHHCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCEEECCCEEEEECCCHHHHH
VVWAKLEENGKDAIRGFILEKGWRGLSAPTIHSKVGLRASITGEIVLDEVFVPEENRFPE
HHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHCCCEEECCCEEEEEEEECCCCCCCCC
VSGLRGPFTCLNSARYGIAWGALGAAEACWHTARQYVLDRKQFGRPLAANQLIQKKLADM
CCCCCCCHHHHCCCCCCEEHHCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
QTEITLGLQGVLRLGRMKDEGTAAVEITSIMKRNSCGKALDIARLARDMLGGNGISDEFG
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHH
VARHLVNLEVVNTYEGTHDIHALILGRAQTGIQAFF
HHHHHHEEEEEECCCCCHHHHHHEEHHHHCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glutaryl-CoA; acceptor

Specific reaction: glutaryl-CoA + acceptor = crotonoyl-CoA + CO2 + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]