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The map label for this gene is lptD

Identifier: 91781821

GI number: 91781821

Start: 489314

End: 491683

Strand: Direct

Name: lptD

Synonym: Bxe_A4024

Alternate gene names: 91781821

Gene position: 489314-491683 (Clockwise)

Preceding gene: 91781818

Following gene: 91781822

Centisome position: 9.99

GC content: 63.63

Gene sequence:

>2370_bases
ATGCCGCCTAGACAGCTTTCCCAAACGACTCCCTCTTGTGCCGTAGTGCCGCGCAAAAGGCGGCTCGTCGCGGCGTTGAT
CGCCGTTCCGGGCCTGATGCCCGCGCTTGCGCACGCCCAGCTGGTGGGGGAAGCTGCGCAGCCGCAACCGATCGACGCGC
CCTGGGGTATGCAGCTCGCTCCGCAGCTCGAAGAACGTCCGCTGCAGCCCGGCCAGAAGCCGGCCACGTTCGTGCTCGGC
GACACCACGAGCGGCACCACCGACCAGGACATGGCCGCCAAGGGCTCGGCCGAAGTGCGCCGCAATACGGTCGTCATCAA
GGCCGACGCGCTGCATTACGACCAGGACACGGACATGGCCGACGCGTACGGCTCGGTCCACGTGGTCAACAACGGCAATT
CGTTCGTCGGGCCCGAAGCGCATATGCGCGTGGATTCGAGCGAAGGCTTCATGACCGCGCCGAAGTACCACTTCAACGTG
ACGGGCGGCTCGGGCAGCGCGGAGCGCGTCGACCTGCTCGACAACGAACGCTCGGTCTTCACCAAAGGCACCTACACGGC
GTGCGCGTGCGCGGACGATCCGGCCTGGTACATCAAGGGCAGCGAGTTCGATTTCGACACCGGCGCGGACGAAGGCGTCG
CCCATAACGGCGTGCTGTTCTTCCAGGGCTTTCCGGTGTTCGCTTCGCCCTGGCTGTCGTTCCCGCTCTCGGGCGAACGG
CGCAGCGGGGTGCTGCCGCCCACGTTCTCGCTGAGTTCGTCGAACGGCTTCGAACTGTCGGTGCCGTATTACTTCAACAT
CGCGCCGAATCGCGATCTGACGCTCACGCCGCGTCTGATCTCCAAGCGCGGTGTGCAGTTGCAGTCCACGTTCCGCTATC
TGTCGCCCACGTATTCCGGCTCGATCACCGGCGAATTCCTGCCGGACGATCACCTGACCAAGACCAACCGCTACGCGCTG
TATATCCAGCACAACCAGAACTTCGGCAACGGGTTCGGCGGCTACATCTACTACAACAAGGTCTCGGACAACACGTATCC
GGAAGACCTGTCGTCGTCGGTCAACCAGTTCATGAACGGCACCCAGCTCCTGTATCAGCAGGAAGCCGGGTTGACCTACA
ACAACGGTCCGTGGTCGGTGCTCGCGCGTGAACAGCACTGGCAGACGCTCACGCCGTCCGTGGCGCCGTACGGCCGCGAG
CCGCAGTTGAACGTGAAGTACGCGAAGTACAACGTCGGCGGCTTCGACTACGGCGCGGAAGCCGACTACTCGAATTTCCG
CATCACCACCGCGGACATGACCCAGGGTCAGCGGGTGATGTTCAACCCGTACCTGTCGTATTCGGTGGTCGGGCCGGGTT
ACTTCGTCACGCCGAAGGTGCAATGGCACTTTGCGTCGTACAACCTGAACCACCTGAGCGACGCCGACGTCGCGGCCGGC
ACGCCGAAAAACTTTACCGAATCGATCCCCACCCTCACGTTCGATACGGGACTGGTCTTCGACCGCTCGGTACGGATCTT
CGGTCAGGATTACATCCAGACGCTCGAGCCGCGCCTGTACTACGTGTACACGCCGTATCGCAACCAGCAGTCGGCACCGC
TGTTCGACACCGCCGATTCGGATTTCGGGCTGGCGGAGATCTTCACGCCGAACACCTTCGTCGGCAATGACCGGATCGCC
GACGCGAACCGCCTGACGGCCGCCCTCACCACGCGTTTCATCGACGCGGCCACGGGCGACGAACGGGCGCGTTTCGTGAT
CGCGCAGCAGTATTACTTTCAGGATCAGCGGGTCACGCTGCAGTCGACTCAAACCAGCGCGCAGGCCACCCATTCGGACC
TGATCGCGGGTGCGTCCCTCAAGCTCGGCGCCGGTTTCGCTTCGGAAACGGCGTTCCAATATAATGCCGACAACAACCAG
TTGGTGAAGACGAGCGTCGGCTTCGGGTTCAGTCCGGCCACCGGCAAGGTGATCAACGTCGCGTACCGCTACACCCGCGC
GAACACCACGCTGGACAACACGCCGATCAATCAGGTGCTGATTTCGGGCCAATGGCCGCTCGCGCACCGCGTGTACGGGG
TCGGCCGTTTCAATTACGACCTGGGCGGGCACCGGATCGTCGACGGCCTGGTCGGCCTGCAATACGACGCCGACTGCTGG
ACGCTCGGCGCCGGGATCCAGCGCTATGCGAACGGCCTGAACACCTCCGGGCAGAATCAGTCGAGCACGCGGTTTCTCGC
GCAGTTGACGTTCAAGGGCTTGTCGAGCGTCGACAACGGGCTGATGACCGCGTTCCGCAGCAGCGTGGCGGGCTACACGC
CGTTGCCGCCGCCGCCGCCGCCGGAATCGCGTTTCACCAATTACGAATGA

Upstream 100 bases:

>100_bases
TTGTAAATATTGATGTGCAGCCGACTGTCACGGTCGGGGTGTGCAGGCGGTGGACCGTGACTGCAGAAGCTGACGGACTG
GCCGATTCGCCAAACGATAC

Downstream 100 bases:

>100_bases
CGCTCGCCCGATCATTTATAAAGTGCGAAAAGACGGGCCAGGCGCGCCCGACATCATTGGAGTATCTGTGGCAATCATGA
AAAAGCTTCGCTTGGCAACG

Product: putative organic solvent tolerance protein

Products: NA

Alternate protein names: Organic solvent tolerance protein

Number of amino acids: Translated: 789; Mature: 788

Protein sequence:

>789_residues
MPPRQLSQTTPSCAVVPRKRRLVAALIAVPGLMPALAHAQLVGEAAQPQPIDAPWGMQLAPQLEERPLQPGQKPATFVLG
DTTSGTTDQDMAAKGSAEVRRNTVVIKADALHYDQDTDMADAYGSVHVVNNGNSFVGPEAHMRVDSSEGFMTAPKYHFNV
TGGSGSAERVDLLDNERSVFTKGTYTACACADDPAWYIKGSEFDFDTGADEGVAHNGVLFFQGFPVFASPWLSFPLSGER
RSGVLPPTFSLSSSNGFELSVPYYFNIAPNRDLTLTPRLISKRGVQLQSTFRYLSPTYSGSITGEFLPDDHLTKTNRYAL
YIQHNQNFGNGFGGYIYYNKVSDNTYPEDLSSSVNQFMNGTQLLYQQEAGLTYNNGPWSVLAREQHWQTLTPSVAPYGRE
PQLNVKYAKYNVGGFDYGAEADYSNFRITTADMTQGQRVMFNPYLSYSVVGPGYFVTPKVQWHFASYNLNHLSDADVAAG
TPKNFTESIPTLTFDTGLVFDRSVRIFGQDYIQTLEPRLYYVYTPYRNQQSAPLFDTADSDFGLAEIFTPNTFVGNDRIA
DANRLTAALTTRFIDAATGDERARFVIAQQYYFQDQRVTLQSTQTSAQATHSDLIAGASLKLGAGFASETAFQYNADNNQ
LVKTSVGFGFSPATGKVINVAYRYTRANTTLDNTPINQVLISGQWPLAHRVYGVGRFNYDLGGHRIVDGLVGLQYDADCW
TLGAGIQRYANGLNTSGQNQSSTRFLAQLTFKGLSSVDNGLMTAFRSSVAGYTPLPPPPPPESRFTNYE

Sequences:

>Translated_789_residues
MPPRQLSQTTPSCAVVPRKRRLVAALIAVPGLMPALAHAQLVGEAAQPQPIDAPWGMQLAPQLEERPLQPGQKPATFVLG
DTTSGTTDQDMAAKGSAEVRRNTVVIKADALHYDQDTDMADAYGSVHVVNNGNSFVGPEAHMRVDSSEGFMTAPKYHFNV
TGGSGSAERVDLLDNERSVFTKGTYTACACADDPAWYIKGSEFDFDTGADEGVAHNGVLFFQGFPVFASPWLSFPLSGER
RSGVLPPTFSLSSSNGFELSVPYYFNIAPNRDLTLTPRLISKRGVQLQSTFRYLSPTYSGSITGEFLPDDHLTKTNRYAL
YIQHNQNFGNGFGGYIYYNKVSDNTYPEDLSSSVNQFMNGTQLLYQQEAGLTYNNGPWSVLAREQHWQTLTPSVAPYGRE
PQLNVKYAKYNVGGFDYGAEADYSNFRITTADMTQGQRVMFNPYLSYSVVGPGYFVTPKVQWHFASYNLNHLSDADVAAG
TPKNFTESIPTLTFDTGLVFDRSVRIFGQDYIQTLEPRLYYVYTPYRNQQSAPLFDTADSDFGLAEIFTPNTFVGNDRIA
DANRLTAALTTRFIDAATGDERARFVIAQQYYFQDQRVTLQSTQTSAQATHSDLIAGASLKLGAGFASETAFQYNADNNQ
LVKTSVGFGFSPATGKVINVAYRYTRANTTLDNTPINQVLISGQWPLAHRVYGVGRFNYDLGGHRIVDGLVGLQYDADCW
TLGAGIQRYANGLNTSGQNQSSTRFLAQLTFKGLSSVDNGLMTAFRSSVAGYTPLPPPPPPESRFTNYE
>Mature_788_residues
PPRQLSQTTPSCAVVPRKRRLVAALIAVPGLMPALAHAQLVGEAAQPQPIDAPWGMQLAPQLEERPLQPGQKPATFVLGD
TTSGTTDQDMAAKGSAEVRRNTVVIKADALHYDQDTDMADAYGSVHVVNNGNSFVGPEAHMRVDSSEGFMTAPKYHFNVT
GGSGSAERVDLLDNERSVFTKGTYTACACADDPAWYIKGSEFDFDTGADEGVAHNGVLFFQGFPVFASPWLSFPLSGERR
SGVLPPTFSLSSSNGFELSVPYYFNIAPNRDLTLTPRLISKRGVQLQSTFRYLSPTYSGSITGEFLPDDHLTKTNRYALY
IQHNQNFGNGFGGYIYYNKVSDNTYPEDLSSSVNQFMNGTQLLYQQEAGLTYNNGPWSVLAREQHWQTLTPSVAPYGREP
QLNVKYAKYNVGGFDYGAEADYSNFRITTADMTQGQRVMFNPYLSYSVVGPGYFVTPKVQWHFASYNLNHLSDADVAAGT
PKNFTESIPTLTFDTGLVFDRSVRIFGQDYIQTLEPRLYYVYTPYRNQQSAPLFDTADSDFGLAEIFTPNTFVGNDRIAD
ANRLTAALTTRFIDAATGDERARFVIAQQYYFQDQRVTLQSTQTSAQATHSDLIAGASLKLGAGFASETAFQYNADNNQL
VKTSVGFGFSPATGKVINVAYRYTRANTTLDNTPINQVLISGQWPLAHRVYGVGRFNYDLGGHRIVDGLVGLQYDADCWT
LGAGIQRYANGLNTSGQNQSSTRFLAQLTFKGLSSVDNGLMTAFRSSVAGYTPLPPPPPPESRFTNYE

Specific function: Involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis

COG id: COG1452

COG function: function code M; Organic solvent tolerance protein OstA

Gene ontology:

Cell location: Cell outer membrane

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptD family

Homologues:

Organism=Escherichia coli, GI1786239, Length=750, Percent_Identity=25.7333333333333, Blast_Score=235, Evalue=9e-63,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): LPTD_BURXL (Q145L4)

Other databases:

- EMBL:   CP000270
- RefSeq:   YP_557027.1
- GeneID:   4004338
- GenomeReviews:   CP000270_GR
- KEGG:   bxe:Bxe_A4024
- HOGENOM:   HBG701380
- OMA:   INGYKIG
- ProtClustDB:   CLSK896578
- HAMAP:   MF_01411
- InterPro:   IPR020889
- InterPro:   IPR007543

Pfam domain/function: PF04453 OstA_C

EC number: NA

Molecular weight: Translated: 86740; Mature: 86609

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPRQLSQTTPSCAVVPRKRRLVAALIAVPGLMPALAHAQLVGEAAQPQPIDAPWGMQLA
CCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
PQLEERPLQPGQKPATFVLGDTTSGTTDQDMAAKGSAEVRRNTVVIKADALHYDQDTDMA
CCHHHCCCCCCCCCCEEEEECCCCCCCCHHHHCCCCCCEEECEEEEEECCEECCCCCCHH
DAYGSVHVVNNGNSFVGPEAHMRVDSSEGFMTAPKYHFNVTGGSGSAERVDLLDNERSVF
HCCCEEEEEECCCCEECCCCEEEEECCCCEEECCEEEEEEECCCCCCEEEEECCCCCCEE
TKGTYTACACADDPAWYIKGSEFDFDTGADEGVAHNGVLFFQGFPVFASPWLSFPLSGER
ECCCEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCEEEEECCCHHCCCHHCCCCCCCC
RSGVLPPTFSLSSSNGFELSVPYYFNIAPNRDLTLTPRLISKRGVQLQSTFRYLSPTYSG
CCCCCCCCEECCCCCCEEEECCEEEEECCCCCEEECHHHHHHCCCCHHHHHHHHCCCCCC
SITGEFLPDDHLTKTNRYALYIQHNQNFGNGFGGYIYYNKVSDNTYPEDLSSSVNQFMNG
CEEECCCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCC
TQLLYQQEAGLTYNNGPWSVLAREQHWQTLTPSVAPYGREPQLNVKYAKYNVGGFDYGAE
CEEEEECCCCCEECCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCC
ADYSNFRITTADMTQGQRVMFNPYLSYSVVGPGYFVTPKVQWHFASYNLNHLSDADVAAG
CCCCCEEEEEECCCCCCEEEECCCEEEEEECCCEEECCEEEEEEEEECCCCCCCCCCCCC
TPKNFTESIPTLTFDTGLVFDRSVRIFGQDYIQTLEPRLYYVYTPYRNQQSAPLFDTADS
CCCCHHHCCCEEEECCCEEEECEEEEECHHHHHHCCCEEEEEECCCCCCCCCCCEECCCC
DFGLAEIFTPNTFVGNDRIADANRLTAALTTRFIDAATGDERARFVIAQQYYFQDQRVTL
CCCEEEEECCCEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCEEEE
QSTQTSAQATHSDLIAGASLKLGAGFASETAFQYNADNNQLVKTSVGFGFSPATGKVINV
ECCCCHHHHHHHHHHCCCCEEECCCCCCCCEEEECCCCCEEEEEECCCCCCCCCCCEEEE
AYRYTRANTTLDNTPINQVLISGQWPLAHRVYGVGRFNYDLGGHRIVDGLVGLQYDADCW
EEEEEECCCCCCCCCCCEEEEECCCCHHHHEEEEEEEEECCCCHHHHHHHHCCEECCCCE
TLGAGIQRYANGLNTSGQNQSSTRFLAQLTFKGLSSVDNGLMTAFRSSVAGYTPLPPPPP
EHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
PESRFTNYE
CCCCCCCCC
>Mature Secondary Structure 
PPRQLSQTTPSCAVVPRKRRLVAALIAVPGLMPALAHAQLVGEAAQPQPIDAPWGMQLA
CCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
PQLEERPLQPGQKPATFVLGDTTSGTTDQDMAAKGSAEVRRNTVVIKADALHYDQDTDMA
CCHHHCCCCCCCCCCEEEEECCCCCCCCHHHHCCCCCCEEECEEEEEECCEECCCCCCHH
DAYGSVHVVNNGNSFVGPEAHMRVDSSEGFMTAPKYHFNVTGGSGSAERVDLLDNERSVF
HCCCEEEEEECCCCEECCCCEEEEECCCCEEECCEEEEEEECCCCCCEEEEECCCCCCEE
TKGTYTACACADDPAWYIKGSEFDFDTGADEGVAHNGVLFFQGFPVFASPWLSFPLSGER
ECCCEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCEEEEECCCHHCCCHHCCCCCCCC
RSGVLPPTFSLSSSNGFELSVPYYFNIAPNRDLTLTPRLISKRGVQLQSTFRYLSPTYSG
CCCCCCCCEECCCCCCEEEECCEEEEECCCCCEEECHHHHHHCCCCHHHHHHHHCCCCCC
SITGEFLPDDHLTKTNRYALYIQHNQNFGNGFGGYIYYNKVSDNTYPEDLSSSVNQFMNG
CEEECCCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCC
TQLLYQQEAGLTYNNGPWSVLAREQHWQTLTPSVAPYGREPQLNVKYAKYNVGGFDYGAE
CEEEEECCCCCEECCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCC
ADYSNFRITTADMTQGQRVMFNPYLSYSVVGPGYFVTPKVQWHFASYNLNHLSDADVAAG
CCCCCEEEEEECCCCCCEEEECCCEEEEEECCCEEECCEEEEEEEEECCCCCCCCCCCCC
TPKNFTESIPTLTFDTGLVFDRSVRIFGQDYIQTLEPRLYYVYTPYRNQQSAPLFDTADS
CCCCHHHCCCEEEECCCEEEECEEEEECHHHHHHCCCEEEEEECCCCCCCCCCCEECCCC
DFGLAEIFTPNTFVGNDRIADANRLTAALTTRFIDAATGDERARFVIAQQYYFQDQRVTL
CCCEEEEECCCEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCEEEE
QSTQTSAQATHSDLIAGASLKLGAGFASETAFQYNADNNQLVKTSVGFGFSPATGKVINV
ECCCCHHHHHHHHHHCCCCEEECCCCCCCCEEEECCCCCEEEEEECCCCCCCCCCCEEEE
AYRYTRANTTLDNTPINQVLISGQWPLAHRVYGVGRFNYDLGGHRIVDGLVGLQYDADCW
EEEEEECCCCCCCCCCCEEEEECCCCHHHHEEEEEEEEECCCCHHHHHHHHCCEECCCCE
TLGAGIQRYANGLNTSGQNQSSTRFLAQLTFKGLSSVDNGLMTAFRSSVAGYTPLPPPPP
EHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
PESRFTNYE
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA