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The map label for this gene is glmS [H]

Identifier: 91781692

GI number: 91781692

Start: 341606

End: 342613

Strand: Direct

Name: glmS [H]

Synonym: Bxe_A4154

Alternate gene names: 91781692

Gene position: 341606-342613 (Clockwise)

Preceding gene: 91781691

Following gene: 91781693

Centisome position: 6.98

GC content: 66.57

Gene sequence:

>1008_bases
ATGCTTAAAGAGGCGCTGGCGTCCGCTGAAACGGTCGCCGCGCAACTCATGGATACCTCGCGCGTCGAGGCATTGGCGGC
GAAGCTTGCGCAGCAGCCGCGTCATGTCGCGCTGACGGTCGCGCGCGGCAGCTCCGACCATGCTGCGAGTTACTTCGCCA
GCCTGACGATGAGCCGCCTCGGCGTGCCGGTCGCCTCGCTGCCGATGTCGGTCGCCACGCTCCAGCAAGCGCCGCTGCAG
GTGTGCGATCAGCTCGCGCTGGCCTTCTCGCAATCGGGCAAGAGCCCGGATCTGGTCGGCACGATGGAAGCGCTGCGCAA
AGCGGGCGCCTTGACGGTAGCCGCTGTCAACGTGTCGGGCTCACCCCTGGCCGACGCGTGCGAATTCGAGTTGCCGCTCG
TCGCCGGTCCGGAACTGAGCGTCGCGGCCACCAAGAGCTATATCGCGATGCTGTCGATTTCCGCGCAACTCGTCGCGCAT
TGGCAGAAAGACGCCGAACTGCTCGCGGCGTTGAAGACGCTGCCCGAAGCACTGCGTGCGGCAGGCAAGCTCGACTGGTC
GAATGCCGTGGAGGAATTGCGCGGCGTGGAGCGCATGATCGTGATCGGTCGCGGTCTGGGTCTTGCAATCGCGCAGGAAG
CCGCGTTGAAACTGAAGGAAACCTCCGGCATTCAGGCCGAAGCGTTTTCGAGCGCGGAAGTGCGTCACGGTCCGATGGAA
CTGATCGACCGCGACTACCCGCTGCTGGTCTTCGCACCGCGCGGTCCGGAACAGGCCGGCTTGCTGCAACTCGCGCGCGA
CATGCAGGCGCGCGGCGCCCGTGTTCTGCTCGCGGCGCCGGCCGACGTGCCGGAAGCCACGCTGCCGCTCGCCATCACCG
CTCATGCGGCGCTCGATCCGATCGCCGCCATCCTGTCCTTTTACGTGATGGCAGCCGGCCTTGCCGCCGCGCGCGGGCGC
AATCCCGATGCGCCGCGCCATCTCAACAAAGTCACCGAAACTCACTGA

Upstream 100 bases:

>100_bases
CGCGGCCGCATCGCGCGCGGTGCATGGGCCGACGTGGTCGTGTTCGATCGTGAACTGGCGTTGAGCGCGACTTACGTCGA
AGGAGAAGCAATTGTCGAAT

Downstream 100 bases:

>100_bases
CGAGAAATCAGATGCGACGTGTCGAGGAGTCCCGCTTGATGAGCCATTCTGAAGGCCATATCGTTTTACTCGCGCCCATG
ACCGGTCCGGTCGTGCCGCT

Product: glutamine-fructose-6-phosphate transaminase(isomerizing)

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MLKEALASAETVAAQLMDTSRVEALAAKLAQQPRHVALTVARGSSDHAASYFASLTMSRLGVPVASLPMSVATLQQAPLQ
VCDQLALAFSQSGKSPDLVGTMEALRKAGALTVAAVNVSGSPLADACEFELPLVAGPELSVAATKSYIAMLSISAQLVAH
WQKDAELLAALKTLPEALRAAGKLDWSNAVEELRGVERMIVIGRGLGLAIAQEAALKLKETSGIQAEAFSSAEVRHGPME
LIDRDYPLLVFAPRGPEQAGLLQLARDMQARGARVLLAAPADVPEATLPLAITAHAALDPIAAILSFYVMAAGLAAARGR
NPDAPRHLNKVTETH

Sequences:

>Translated_335_residues
MLKEALASAETVAAQLMDTSRVEALAAKLAQQPRHVALTVARGSSDHAASYFASLTMSRLGVPVASLPMSVATLQQAPLQ
VCDQLALAFSQSGKSPDLVGTMEALRKAGALTVAAVNVSGSPLADACEFELPLVAGPELSVAATKSYIAMLSISAQLVAH
WQKDAELLAALKTLPEALRAAGKLDWSNAVEELRGVERMIVIGRGLGLAIAQEAALKLKETSGIQAEAFSSAEVRHGPME
LIDRDYPLLVFAPRGPEQAGLLQLARDMQARGARVLLAAPADVPEATLPLAITAHAALDPIAAILSFYVMAAGLAAARGR
NPDAPRHLNKVTETH
>Mature_335_residues
MLKEALASAETVAAQLMDTSRVEALAAKLAQQPRHVALTVARGSSDHAASYFASLTMSRLGVPVASLPMSVATLQQAPLQ
VCDQLALAFSQSGKSPDLVGTMEALRKAGALTVAAVNVSGSPLADACEFELPLVAGPELSVAATKSYIAMLSISAQLVAH
WQKDAELLAALKTLPEALRAAGKLDWSNAVEELRGVERMIVIGRGLGLAIAQEAALKLKETSGIQAEAFSSAEVRHGPME
LIDRDYPLLVFAPRGPEQAGLLQLARDMQARGARVLLAAPADVPEATLPLAITAHAALDPIAAILSFYVMAAGLAAARGR
NPDAPRHLNKVTETH

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG2222

COG function: function code M; Predicted phosphosugar isomerases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=264, Percent_Identity=28.030303030303, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI205277386, Length=263, Percent_Identity=26.9961977186312, Blast_Score=103, Evalue=2e-22,
Organism=Escherichia coli, GI1790167, Length=264, Percent_Identity=29.5454545454545, Blast_Score=101, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17539970, Length=266, Percent_Identity=27.8195488721804, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17532899, Length=264, Percent_Identity=27.2727272727273, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17532897, Length=264, Percent_Identity=27.2727272727273, Blast_Score=105, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6322745, Length=308, Percent_Identity=26.6233766233766, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6323731, Length=183, Percent_Identity=26.775956284153, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21357745, Length=353, Percent_Identity=25.2124645892351, Blast_Score=110, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 35022; Mature: 35022

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKEALASAETVAAQLMDTSRVEALAAKLAQQPRHVALTVARGSSDHAASYFASLTMSRL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHH
GVPVASLPMSVATLQQAPLQVCDQLALAFSQSGKSPDLVGTMEALRKAGALTVAAVNVSG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEEEECCC
SPLADACEFELPLVAGPELSVAATKSYIAMLSISAQLVAHWQKDAELLAALKTLPEALRA
CCCCCHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGKLDWSNAVEELRGVERMIVIGRGLGLAIAQEAALKLKETSGIQAEAFSSAEVRHGPME
HCCCCHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHCCCCCHHHCCCCHHCCCCHH
LIDRDYPLLVFAPRGPEQAGLLQLARDMQARGARVLLAAPADVPEATLPLAITAHAALDP
HHCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEHHHHHHH
IAAILSFYVMAAGLAAARGRNPDAPRHLNKVTETH
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MLKEALASAETVAAQLMDTSRVEALAAKLAQQPRHVALTVARGSSDHAASYFASLTMSRL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHH
GVPVASLPMSVATLQQAPLQVCDQLALAFSQSGKSPDLVGTMEALRKAGALTVAAVNVSG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEEEECCC
SPLADACEFELPLVAGPELSVAATKSYIAMLSISAQLVAHWQKDAELLAALKTLPEALRA
CCCCCHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGKLDWSNAVEELRGVERMIVIGRGLGLAIAQEAALKLKETSGIQAEAFSSAEVRHGPME
HCCCCHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHCCCCCHHHCCCCHHCCCCHH
LIDRDYPLLVFAPRGPEQAGLLQLARDMQARGARVLLAAPADVPEATLPLAITAHAALDP
HHCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEHHHHHHH
IAAILSFYVMAAGLAAARGRNPDAPRHLNKVTETH
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10382966 [H]